NO2480669T3 - - Google Patents

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Publication number
NO2480669T3
NO2480669T3 NO10819521A NO10819521A NO2480669T3 NO 2480669 T3 NO2480669 T3 NO 2480669T3 NO 10819521 A NO10819521 A NO 10819521A NO 10819521 A NO10819521 A NO 10819521A NO 2480669 T3 NO2480669 T3 NO 2480669T3
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Norway
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NO10819521A
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
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    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
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    • C12N2310/3231Chemical structure of the sugar modified ring structure having an additional ring, e.g. LNA, ENA

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  • Immunology (AREA)
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  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
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NO10819521A 2009-09-25 2010-09-24 NO2480669T3 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24608009P 2009-09-25 2009-09-25
US30765410P 2010-02-24 2010-02-24
PCT/US2010/050173 WO2011038210A2 (en) 2009-09-25 2010-09-24 Treatment of filaggrin (flg) related diseases by modulation of flg expression and activity

Publications (1)

Publication Number Publication Date
NO2480669T3 true NO2480669T3 (no) 2018-04-07

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NO10819521A NO2480669T3 (no) 2009-09-25 2010-09-24

Country Status (10)

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US (3) US20120295952A1 (no)
EP (1) EP2480669B1 (no)
JP (3) JP6175236B2 (no)
KR (1) KR101802540B1 (no)
CN (1) CN102791861B (no)
CA (1) CA2775111C (no)
DK (1) DK2480669T3 (no)
ES (1) ES2664591T3 (no)
NO (1) NO2480669T3 (no)
WO (1) WO2011038210A2 (no)

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AU2013262700A1 (en) 2012-05-16 2015-01-22 Rana Therapeutics, Inc. Compositions and methods for modulating hemoglobin gene family expression
US10059941B2 (en) 2012-05-16 2018-08-28 Translate Bio Ma, Inc. Compositions and methods for modulating SMN gene family expression
US10174323B2 (en) 2012-05-16 2019-01-08 The General Hospital Corporation Compositions and methods for modulating ATP2A2 expression
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US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
EP3033422A4 (en) 2013-08-16 2017-08-02 Rana Therapeutics Inc. Oligonucleotides targeting euchromatin regions of genes
CA2979079A1 (en) 2014-05-30 2015-12-03 Azitra, Inc. Therapeutic treatment of skin disease with recombinant commensal skin microorganisms
AU2015287299A1 (en) * 2014-07-09 2017-02-02 Sun Pharmaceutical Industries Limited Capsule dosage form of metoprolol succinate
WO2016010988A1 (en) 2014-07-14 2016-01-21 Novan, Inc. Nitric oxide releasing nail coating compositions, nitric oxide releasing nail coatings, and methods of using the same
US10858650B2 (en) 2014-10-30 2020-12-08 The General Hospital Corporation Methods for modulating ATRX-dependent gene repression
EP3256591A4 (en) 2015-02-13 2018-08-08 Translate Bio Ma, Inc. Hybrid oligonucleotides and uses thereof
US10900036B2 (en) 2015-03-17 2021-01-26 The General Hospital Corporation RNA interactome of polycomb repressive complex 1 (PRC1)
WO2017019614A1 (en) 2015-07-28 2017-02-02 Novan, Inc. Combinations and methods for the treatment and/or prevention of fungal infections
CN106728555A (zh) * 2016-12-07 2017-05-31 郑州仁宏医药科技有限公司 一种用于修复疤痕的西药组合及其制备方法
CN111278447A (zh) * 2017-09-05 2020-06-12 阿兹特拉公司 用重组微生物治疗炎性皮肤疾病的方法和组合物
CN116874576B (zh) * 2023-06-28 2024-03-12 胡荣洋 一种重组人源化丝聚蛋白及其制备方法和应用

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US20190024084A1 (en) 2019-01-24
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EP2480669A4 (en) 2013-07-31
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KR20120091074A (ko) 2012-08-17
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