ES2182832T3 - Procedimiento para la produccion de una proteina recombinante de antigeno chmii en microorganismos. - Google Patents
Procedimiento para la produccion de una proteina recombinante de antigeno chmii en microorganismos.Info
- Publication number
- ES2182832T3 ES2182832T3 ES93922634T ES93922634T ES2182832T3 ES 2182832 T3 ES2182832 T3 ES 2182832T3 ES 93922634 T ES93922634 T ES 93922634T ES 93922634 T ES93922634 T ES 93922634T ES 2182832 T3 ES2182832 T3 ES 2182832T3
- Authority
- ES
- Spain
- Prior art keywords
- mhc class
- chmii
- microorganisms
- procedure
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Abstract
UN PROCESO PARA PRODUCIR UNA PROTEINA DE CLASE II ANTIGENA DE MAS HISTOCOMPATIBILIDAD (MHC CLASE II) ENCONTRADA, POR EJEMPLO, SOBRE LA SUPERFICIE DE UNA CELULA QUE PRESENTA ANTIGENO; UN MATERIAL QUE TIENE EL MHC CLASE II INMOVILIZADO ENCIMA, PREPARADO MEDIANTE UNION DEL MHC CLASE II, LAS SUBUNIDADES Y/O (BETA) DEL MHC CLASE II, O UNA PARTE DE LAS MISMAS A UN MATERIAL TAL COMO PERLA, FIBRA O HILO HUECO, A TRAVES DE ENLACE COVALENTE; Y UN MODULO DE EXTRACCION SUPERANTIGENO, PREPARADO DEL MATERIAL. LA INVENCION TAMBIEN PROPORCIONA UN METODO PARA DETECTAR O ENSAYAR UN SUPERANTIGENO, USANDO EL MHC CLASE II, O ESA PARTE DEL MHC CLASE II QUE TIENE UNA AFINIDAD PARA UN SUPERANTIGENO, Y UN EQUIPO DE ENSAYO PARA ELLO.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP27743092 | 1992-10-15 | ||
JP34591792 | 1992-12-25 | ||
JP34591592 | 1992-12-25 | ||
JP34591892 | 1992-12-25 | ||
JP34591692 | 1992-12-25 | ||
PCT/JP1993/001480 WO1994009148A1 (en) | 1992-10-15 | 1993-10-15 | Process for producing major histocompatibility antigen class ii protein and material having the same immobilized thereon |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2182832T3 true ES2182832T3 (es) | 2003-03-16 |
Family
ID=27530641
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93922634T Expired - Lifetime ES2182832T3 (es) | 1992-10-15 | 1993-10-15 | Procedimiento para la produccion de una proteina recombinante de antigeno chmii en microorganismos. |
Country Status (10)
Country | Link |
---|---|
US (1) | US6630315B1 (es) |
EP (2) | EP0636696B1 (es) |
JP (3) | JP2003130872A (es) |
KR (1) | KR0169751B1 (es) |
AT (1) | ATE223485T1 (es) |
AU (1) | AU674891B2 (es) |
CA (1) | CA2125871A1 (es) |
DE (1) | DE69332268T2 (es) |
ES (1) | ES2182832T3 (es) |
WO (1) | WO1994009148A1 (es) |
Families Citing this family (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL320922A1 (en) * | 1994-12-23 | 1997-11-10 | Om Lab Sa | Application of mhc-ii bonding and/or somulating molecules in prevention and/or treatment of diseases involving inflammatory processes |
US6620382B1 (en) | 1998-05-22 | 2003-09-16 | Biopheresis Technologies, Llc. | Method and compositions for treatment of cancers |
US8197430B1 (en) | 1998-05-22 | 2012-06-12 | Biopheresis Technologies, Inc. | Method and system to remove cytokine inhibitor in patients |
US6379708B1 (en) * | 1999-11-20 | 2002-04-30 | Cytologic, Llc | Method for enhancing immune responses in mammals |
CA2440773A1 (en) * | 2001-03-14 | 2002-09-19 | Dakocytomation Denmark A/S | Novel mhc molecule constructs, and methods of employing these constructs for diagnosis and therapy, and uses of mhc molecules |
US20040072262A1 (en) | 2002-10-11 | 2004-04-15 | Montero-Julian Felix A. | Methods and systems for detecting MHC class I binding peptides |
US20040248205A1 (en) * | 2003-04-16 | 2004-12-09 | Stern Lawrence J. | Major histocompatibility complex (MHC)-peptide arrays |
WO2005111616A1 (ja) * | 2004-05-14 | 2005-11-24 | Toray Industries, Inc. | 標的物質を迅速簡便に検出する方法およびそのための酵素免疫学的キット |
JP4839674B2 (ja) * | 2004-05-14 | 2011-12-21 | 東レ株式会社 | 標的物質を迅速簡便に検出する方法およびそのための酵素免疫学的キット |
EP1781313A4 (en) | 2004-06-17 | 2009-08-26 | Beckman Coulter Inc | MYCOBACTERIUM TUBERCULOSIS EPITOPES AND METHODS OF USE |
WO2007008488A2 (en) * | 2005-07-06 | 2007-01-18 | Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Stable quantitation and detection of immune response levels with non-zero background peptides |
US20070065514A1 (en) * | 2005-09-22 | 2007-03-22 | Howell Mark D | Method for enhancing immune responses in mammals |
EP1976567B1 (en) | 2005-12-28 | 2020-05-13 | The Scripps Research Institute | Natural antisense and non-coding rna transcripts as drug targets |
US20080075690A1 (en) * | 2006-09-22 | 2008-03-27 | Mark Douglas Howell | Method for enhancing immune responses in mammals |
EP2361930A3 (en) | 2007-03-26 | 2011-10-26 | Dako Denmark A/S | Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases |
EP3023436A1 (en) | 2007-07-03 | 2016-05-25 | Dako Denmark A/S | Improved methods for generation, labeling and use of mhc multimers |
WO2009039854A2 (en) | 2007-09-27 | 2009-04-02 | Dako Denmark A/S | Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics |
US10968269B1 (en) | 2008-02-28 | 2021-04-06 | Agilent Technologies, Inc. | MHC multimers in borrelia diagnostics and disease |
WO2010009735A2 (en) | 2008-07-23 | 2010-01-28 | Dako Denmark A/S | Combinatorial analysis and repair |
GB0817244D0 (en) | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
US10369204B2 (en) | 2008-10-02 | 2019-08-06 | Dako Denmark A/S | Molecular vaccines for infectious disease |
US8153606B2 (en) | 2008-10-03 | 2012-04-10 | Opko Curna, Llc | Treatment of apolipoprotein-A1 related diseases by inhibition of natural antisense transcript to apolipoprotein-A1 |
EP2370582B1 (en) | 2008-12-04 | 2017-05-10 | CuRNA, Inc. | Treatment of tumor suppressor gene related diseases by inhibition of natural antisense transcript to the gene |
US8927511B2 (en) | 2008-12-04 | 2015-01-06 | Curna, Inc. | Treatment of vascular endothelial growth factor (VEGF) related diseases by inhibition of natural antisense transcript to VEGF |
ES2629630T3 (es) | 2008-12-04 | 2017-08-11 | Curna, Inc. | Tratamiento de enfermedades relacionadas con eritropoyetina (EPO) mediante inhibición del transcrito antisentido natural a EPO |
ES2560107T3 (es) | 2009-02-12 | 2016-02-17 | Curna, Inc. | Tratamiento de enfermedades relacionadas con el factor neurotrófico derivado de cerebro (BDNF) por inhibición de transcrito antisentido natural para BDNF |
CA2755409C (en) | 2009-03-16 | 2019-04-30 | Joseph Collard | Treatment of nuclear factor (erythroid-derived 2)-like 2 (nrf2) related diseases by inhibition of natural antisense transcript to nrf2 |
JP5904935B2 (ja) | 2009-03-17 | 2016-04-20 | クルナ・インコーポレーテッド | デルタ様1ホモログ(dlk1)に対する天然アンチセンス転写物の抑制によるdlk1関連疾患の治療 |
KR101722541B1 (ko) | 2009-05-06 | 2017-04-04 | 큐알엔에이, 인크. | Ttp에 대한 천연 안티센스 전사체의 억제에 의한 트리스테트라프롤린 관련된 질환의 치료 |
CN102459596B (zh) | 2009-05-06 | 2016-09-07 | 库尔纳公司 | 通过针对脂质转运和代谢基因的天然反义转录物的抑制治疗脂质转运和代谢基因相关疾病 |
CA2761248C (en) | 2009-05-08 | 2023-03-14 | Joseph Collard | Treatment of dystrophin family related diseases by inhibition of natural antisense transcript to dmd family |
ES2664590T3 (es) | 2009-05-18 | 2018-04-20 | Curna, Inc. | Tratamiento de enfermedades relacionadas con factores de reprogramación por inhibición del tránscrito antisentido natural a un factor de reprogramación |
US8895527B2 (en) | 2009-05-22 | 2014-11-25 | Curna, Inc. | Treatment of transcription factor E3 (TFE3) and insulin receptor substrate 2(IRS2) related diseases by inhibition of natural antisense transcript to TFE3 |
WO2010138806A2 (en) | 2009-05-28 | 2010-12-02 | Curna, Inc. | Treatment of antiviral gene related diseases by inhibition of natural antisense transcript to an antiviral gene |
US8951981B2 (en) | 2009-06-16 | 2015-02-10 | Curna, Inc. | Treatment of paraoxonase 1 (PON1) related diseases by inhibition of natural antisense transcript to PON1 |
JP5944311B2 (ja) | 2009-06-16 | 2016-07-05 | クルナ・インコーポレーテッド | コラーゲン遺伝子に対する天然アンチセンス転写物の抑制によるコラーゲン遺伝子関連疾患の治療 |
JP6073133B2 (ja) | 2009-06-24 | 2017-02-01 | クルナ・インコーポレーテッド | 腫瘍壊死因子受容体2(tnfr2)に対する天然アンチセンス転写物の抑制によるtnfr2関連疾患の治療 |
EP2446037B1 (en) | 2009-06-26 | 2016-04-20 | CuRNA, Inc. | Treatment of down syndrome gene related diseases by inhibition of natural antisense transcript to a down syndrome gene |
US20120252869A1 (en) | 2009-07-24 | 2012-10-04 | Opko Curna, Llc | Treatment of sirtuin (sirt) related diseases by inhibition of natural antisense transcript to a sirtuin (sirt) |
CN102762731B (zh) | 2009-08-05 | 2018-06-22 | 库尔纳公司 | 通过抑制针对胰岛素基因(ins)的天然反义转录物来治疗胰岛素基因(ins)相关的疾病 |
CN104313027B (zh) | 2009-08-11 | 2018-11-20 | 库尔纳公司 | 通过抑制脂连蛋白(adipoq)的天然反义转录物治疗脂连蛋白(adipoq)相关疾病 |
KR101805213B1 (ko) | 2009-08-21 | 2017-12-06 | 큐알엔에이, 인크. | Chip에 대한 천연 안티센스 전사체의 억제에 의한 “hsp70-상호작용 단백질(chip)의 c-말단” 관련된 질환의 치료 |
WO2011031482A2 (en) | 2009-08-25 | 2011-03-17 | Curna, Inc. | Treatment of 'iq motif containing gtpase activating protein' (iqgap) related diseases by inhibition of natural antisense transcript to iqgap |
CN102791861B (zh) | 2009-09-25 | 2018-08-07 | 库尔纳公司 | 通过调节聚丝蛋白(flg)的表达和活性而治疗flg相关疾病 |
ES2661813T3 (es) | 2009-12-16 | 2018-04-04 | Curna, Inc. | Tratamiento de enfermedades relacionadas con la peptidasa del factor de transcripción de membrana, sitio 1 (mbtps1) mediante inhibición del transcrito antisentido natural al gen mbtps1 |
JP5934106B2 (ja) | 2009-12-23 | 2016-06-15 | カッパーアールエヌエー,インコーポレイテッド | 肝細胞増殖因子(hgf)に対する天然アンチセンス転写物の阻害によるhgf関連性疾患の治療 |
CA2782375C (en) | 2009-12-23 | 2023-10-31 | Opko Curna, Llc | Treatment of uncoupling protein 2 (ucp2) related diseases by inhibition of natural antisense transcript to ucp2 |
EP2519634B1 (en) | 2009-12-29 | 2016-06-01 | CuRNA, Inc. | TREATMENT OF TUMOR PROTEIN 63 (p63) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO p63 |
US8921334B2 (en) | 2009-12-29 | 2014-12-30 | Curna, Inc. | Treatment of nuclear respiratory factor 1 (NRF1) related diseases by inhibition of natural antisense transcript to NRF1 |
WO2011082281A2 (en) | 2009-12-31 | 2011-07-07 | Curna, Inc. | Treatment of insulin receptor substrate 2 (irs2) related diseases by inhibition of natural antisense transcript to irs2 and transcription factor e3 (tfe3) |
KR101878501B1 (ko) | 2010-01-04 | 2018-08-07 | 큐알엔에이, 인크. | 인터페론 조절 인자 8 (irf8)에 대한 자연 안티센스 전사체의 저해에 의한 인터페론 조절 인자 8 (irf8) 관련된 질환의 치료 |
KR101853509B1 (ko) | 2010-01-06 | 2018-04-30 | 큐알엔에이, 인크. | 췌장 발달 유전자에 대한 천연 안티센스 전사체의 억제에 의한 췌장 발달 유전자와 관련된 질환의 치료 |
ES2664866T3 (es) | 2010-01-11 | 2018-04-23 | Curna, Inc. | Tratamiento de enfermedades relacionadas con la globulina fijadora de hormonas sexuales (shbg) mediante inhibición del transcrito antisentido natural a shbg |
CN102782135A (zh) | 2010-01-25 | 2012-11-14 | 库尔纳公司 | 通过抑制rna酶h1的天然反义转录物而治疗rna酶h1相关疾病 |
US8962586B2 (en) | 2010-02-22 | 2015-02-24 | Curna, Inc. | Treatment of pyrroline-5-carboxylate reductase 1 (PYCR1) related diseases by inhibition of natural antisense transcript to PYCR1 |
KR101877065B1 (ko) | 2010-04-02 | 2018-07-10 | 큐알엔에이, 인크. | 집락 자극 인자 3 (csf3)에 대한 자연 안티센스 전사체의 저해에 의한 집락 자극 인자 3 (csf3) 관련된 질환의 치료 |
CN102858979B (zh) | 2010-04-09 | 2018-01-26 | 库尔纳公司 | 通过抑制成纤维细胞生长因子21(fgf21)的天然反义转录物而治疗fgf21相关疾病 |
WO2011139387A1 (en) | 2010-05-03 | 2011-11-10 | Opko Curna, Llc | Treatment of sirtuin (sirt) related diseases by inhibition of natural antisense transcript to a sirtuin (sirt) |
TWI586356B (zh) | 2010-05-14 | 2017-06-11 | 可娜公司 | 藉由抑制par4天然反股轉錄本治療par4相關疾病 |
NO2576783T3 (es) | 2010-05-26 | 2018-04-28 | ||
RU2620978C2 (ru) | 2010-05-26 | 2017-05-30 | Курна, Инк. | Лечение заболеваний, связанных с метионинсульфоксидредуктазой а (msra), путем ингибирования природного антисмыслового транскрипта гена msra |
JP6023705B2 (ja) | 2010-06-23 | 2016-11-09 | カッパーアールエヌエー,インコーポレイテッド | ナトリウムチャネル、電位依存性、αサブユニット(SCNA)に対する天然アンチセンス転写物の阻害によるSCNA関連疾患の治療 |
US8980860B2 (en) | 2010-07-14 | 2015-03-17 | Curna, Inc. | Treatment of discs large homolog (DLG) related diseases by inhibition of natural antisense transcript to DLG |
US8993533B2 (en) | 2010-10-06 | 2015-03-31 | Curna, Inc. | Treatment of sialidase 4 (NEU4) related diseases by inhibition of natural antisense transcript to NEU4 |
CA2815212A1 (en) | 2010-10-22 | 2012-04-26 | Curna, Inc. | Treatment of alpha-l-iduronidase (idua) related diseases by inhibition of natural antisense transcript to idua |
US10000752B2 (en) | 2010-11-18 | 2018-06-19 | Curna, Inc. | Antagonat compositions and methods of use |
KR102010598B1 (ko) | 2010-11-23 | 2019-08-13 | 큐알엔에이, 인크. | Nanog에 대한 자연 안티센스 전사체의 저해에 의한 nanog 관련된 질환의 치료 |
JP6188686B2 (ja) | 2011-06-09 | 2017-08-30 | カッパーアールエヌエー,インコーポレイテッド | フラタキシン(fxn)への天然アンチセンス転写物の阻害によるfxn関連疾患の治療 |
CN108272782B (zh) | 2011-09-06 | 2021-04-23 | 库尔纳公司 | 小分子在制备治疗Dravet综合征或全面性癫痫伴热性惊厥附加症的药物中的用途 |
CN110438125A (zh) | 2012-03-15 | 2019-11-12 | 科纳公司 | 通过抑制脑源神经营养因子(bdnf)的天然反义转录物治疗bdnf相关疾病 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3382137D1 (de) * | 1982-07-30 | 1991-02-28 | Bernard Francois Mach | Dns-sequenzenkodieren fuer den dr-beta-kettenlocus des menschlichen lymphocytantigenkomplexes und polypeptiden, diagnostische typierungsverfahren und produkte die darauf bezug haben. |
US5194425A (en) * | 1988-06-23 | 1993-03-16 | Anergen, Inc. | Mhc-mediated toxic conjugates useful in ameliorating autoimmunity |
US5130297A (en) * | 1988-06-23 | 1992-07-14 | Anergen, Inc. | Conjugates useful in ameliorating autoimmunity MHC-II-peptide |
US5260422A (en) * | 1988-06-23 | 1993-11-09 | Anergen, Inc. | MHC conjugates useful in ameliorating autoimmunity |
CA2031507A1 (en) * | 1989-04-18 | 1990-10-19 | Bernard Mach | Proteins which regulate the expression of vertebrate mhc class ii genes, dna sequences encoding them and pharmaceutical compositions |
IL92629A0 (en) * | 1989-12-10 | 1990-08-31 | Yeda Res & Dev | Direct binding of t-cell epitopes to mhc gene products on intact living antigen presenting cells and the use thereof for identifying epitopes causing autoimmune diseases and pharmaceutical compositions for treating such diseases |
US5364762A (en) * | 1990-03-21 | 1994-11-15 | Board Of Trustees Of The Leland Stanford Junior University | Major histocompatibility complex (MHC) molecules |
CA2095323A1 (en) * | 1990-10-30 | 1992-05-01 | Jonathan B. Rothbard | Peptide binding assays with mhc antigens |
WO1993009810A1 (en) * | 1991-11-19 | 1993-05-27 | Anergen, Inc. | Mhc subunit conjugates useful in ameliorating deleterious immune responses |
US5292641A (en) * | 1991-12-13 | 1994-03-08 | Sangstat Medical Corporation | Alloantigen testing by binding assay |
US5583031A (en) * | 1992-02-06 | 1996-12-10 | President And Fellows Of Harvard College | Empty major histocompatibility class II heterodimers |
WO1994006813A1 (en) * | 1992-09-15 | 1994-03-31 | The Rockefeller University | Major histocompatibility complex molecules and modifications thereof |
-
1993
- 1993-10-15 AT AT93922634T patent/ATE223485T1/de not_active IP Right Cessation
- 1993-10-15 EP EP93922634A patent/EP0636696B1/en not_active Expired - Lifetime
- 1993-10-15 EP EP01114291A patent/EP1138766A3/en not_active Withdrawn
- 1993-10-15 DE DE69332268T patent/DE69332268T2/de not_active Expired - Fee Related
- 1993-10-15 KR KR1019940702037A patent/KR0169751B1/ko not_active IP Right Cessation
- 1993-10-15 CA CA002125871A patent/CA2125871A1/en not_active Abandoned
- 1993-10-15 AU AU51613/93A patent/AU674891B2/en not_active Ceased
- 1993-10-15 ES ES93922634T patent/ES2182832T3/es not_active Expired - Lifetime
- 1993-10-15 WO PCT/JP1993/001480 patent/WO1994009148A1/ja active IP Right Grant
-
1997
- 1997-09-11 US US08/929,157 patent/US6630315B1/en not_active Expired - Fee Related
-
2002
- 2002-08-07 JP JP2002229843A patent/JP2003130872A/ja active Pending
- 2002-08-07 JP JP2002229842A patent/JP2003070470A/ja active Pending
-
2003
- 2003-08-21 JP JP2003208174A patent/JP2004049238A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE69332268T2 (de) | 2003-08-14 |
KR0169751B1 (ko) | 1999-01-15 |
EP0636696B1 (en) | 2002-09-04 |
JP2003070470A (ja) | 2003-03-11 |
JP2003130872A (ja) | 2003-05-08 |
US6630315B1 (en) | 2003-10-07 |
AU5161393A (en) | 1994-05-09 |
WO1994009148A1 (en) | 1994-04-28 |
AU674891B2 (en) | 1997-01-16 |
EP0636696A1 (en) | 1995-02-01 |
DE69332268D1 (de) | 2002-10-10 |
EP1138766A3 (en) | 2003-05-02 |
EP0636696A4 (en) | 1998-01-07 |
JP2004049238A (ja) | 2004-02-19 |
EP1138766A2 (en) | 2001-10-04 |
KR940703925A (ko) | 1994-12-12 |
ATE223485T1 (de) | 2002-09-15 |
CA2125871A1 (en) | 1994-04-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2182832T3 (es) | Procedimiento para la produccion de una proteina recombinante de antigeno chmii en microorganismos. | |
AU4055697A (en) | Mammalian cell surface antigens; related reagents | |
BR9811039A (pt) | Citocina de mamìferos: interleucina-b30 e reagentes relacionados | |
PT733069E (pt) | Antigenios ctla-8 de primata purificados e reagentes relacionados | |
LU91756I2 (fr) | Denosumab | |
DK0894498T3 (da) | Fremgangsmåde til bestemmelse af kön af pattedyr-afkom | |
ES2063790T3 (es) | Matriz de soporte impregnada de manera desprendible con reactivos. | |
DK0886644T3 (da) | Lang bölgelængde-modificerede fluorescerende proteiner | |
AR022236A1 (es) | Citoquinas mamiferas purificadas; reactivos y metodos relacionados | |
WO1998001557A3 (en) | Mammalian chemokine reagents | |
WO1998011226A3 (en) | Mammalian chemokines, related reagents | |
AR022237A1 (es) | Citoquinas mamiferas purificadas; reactivos y metodos relacionados | |
WO1998032858A3 (en) | Mammalian chemokines; receptors; reagents; uses | |
ATE265533T1 (de) | Saeugetierchemokine | |
FR2599149B1 (fr) | Reactif pour la transparisation de milieux biologiques et ses applications analytiques. | |
DE69534178D1 (en) | S?ugetier thymokingene | |
BR9713632A (pt) | Citocina de mamìfero relacionada com a il-10 | |
WO1998031810A3 (en) | Mammalian chemokines; receptors; reagents; uses | |
ES2165358T3 (es) | Utilizaciones de la proteinquinasa de neurofilamento/tau pk40. | |
AR002004A1 (es) | Proteina slam, anticuerpo o un fragmento del mismo que se fija a dicha proteina, metodo de purificacion, acido nucleico que codifica dicha proteina,vector de expresion, equipo que la contiene, metodo de deteccion, metodo de modulacion y metodo para preparar una composicion farmaceutica. | |
AR016145A1 (es) | Citoquinas de mamifero; reactivos relacionados |