NO20092715L - 5,6,7,8-tetrahydro-imidazo[1,5-A]pyrazinderivater - Google Patents

5,6,7,8-tetrahydro-imidazo[1,5-A]pyrazinderivater

Info

Publication number
NO20092715L
NO20092715L NO20092715A NO20092715A NO20092715L NO 20092715 L NO20092715 L NO 20092715L NO 20092715 A NO20092715 A NO 20092715A NO 20092715 A NO20092715 A NO 20092715A NO 20092715 L NO20092715 L NO 20092715L
Authority
NO
Norway
Prior art keywords
alkyl
imidazo
tetrahydro
alkoxy
halogen
Prior art date
Application number
NO20092715A
Other languages
English (en)
Norwegian (no)
Inventor
Hamed Aissaoui
Christoph Boss
Markus Gude
Ralf Koberstein
Thierry Sifferlen
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of NO20092715L publication Critical patent/NO20092715L/no

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    • C—CHEMISTRY; METALLURGY
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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Addiction (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Otolaryngology (AREA)
NO20092715A 2006-12-22 2009-07-20 5,6,7,8-tetrahydro-imidazo[1,5-A]pyrazinderivater NO20092715L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2006055019 2006-12-22
PCT/IB2007/055245 WO2008078291A1 (en) 2006-12-22 2007-12-20 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives

Publications (1)

Publication Number Publication Date
NO20092715L true NO20092715L (no) 2009-07-20

Family

ID=39273168

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092715A NO20092715L (no) 2006-12-22 2009-07-20 5,6,7,8-tetrahydro-imidazo[1,5-A]pyrazinderivater

Country Status (15)

Country Link
US (1) US8188082B2 (de)
EP (1) EP2125823B1 (de)
JP (1) JP2010513466A (de)
KR (1) KR20090106538A (de)
CN (1) CN101568542B (de)
AT (1) ATE545647T1 (de)
AU (1) AU2007337659A1 (de)
BR (1) BRPI0720522A2 (de)
CA (1) CA2669561A1 (de)
ES (1) ES2380391T3 (de)
MA (1) MA31002B1 (de)
MX (1) MX2009006553A (de)
NO (1) NO20092715L (de)
RU (1) RU2009127842A (de)
WO (1) WO2008078291A1 (de)

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EP2307417A2 (de) * 2008-06-25 2011-04-13 Actelion Pharmaceuticals Ltd. 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazinverbindungen
MX2012004753A (es) 2009-10-23 2012-09-07 Janssen Pharmaceutica Nv Octahidropirrolo[3,4-c]pirrolos disustituidos como moduladores del receptor de orexina.
CN102258508A (zh) * 2011-04-14 2011-11-30 威海迪素制药有限公司 芳基丙烯酸衍生物抗癫痫的用途
WO2013119639A1 (en) 2012-02-07 2013-08-15 Eolas Therapeutics, Inc. Substituted prolines / piperidines as orexin receptor antagonists
US9440982B2 (en) 2012-02-07 2016-09-13 Eolas Therapeutics, Inc. Substituted prolines/piperidines as orexin receptor antagonists
CN103980281B (zh) * 2014-05-27 2016-06-08 天津市斯芬克司药物研发有限公司 一种咪唑吡嗪化合物及其制备方法
ES2901418T3 (es) 2014-08-13 2022-03-22 Eolas Therapeutics Inc Difluoropirrolidinas como moduladores del receptor de orexina
WO2017139603A1 (en) 2016-02-12 2017-08-17 Astrazeneca Ab Halo-substituted piperidines as orexin receptor modulators
HUE058759T2 (hu) 2016-03-10 2022-09-28 Janssen Pharmaceutica Nv Módszerek depresszió kezelésére orexin-2 receptor antagonisták alkalmazásával
CN105753788A (zh) * 2016-04-08 2016-07-13 西南科技大学 一种1-取代-2-苯基-4-碘咪唑的制备方法
EP3454857A1 (de) 2016-05-10 2019-03-20 INSERM (Institut National de la Santé et de la Recherche Médicale) Verfahren und pharmazeutische zusammensetzungen zur behandlung entzündlicher augenkrankheiten
EP3682881A4 (de) 2017-09-14 2021-08-11 Daiichi Sankyo Company, Limited Verbindung mit zyklischer struktur
CN108101930B (zh) * 2017-12-22 2020-10-30 武汉大学 一类含有苯并噻二唑并噻吩单元的小分子受体材料及其制备方法与应用
KR20210003764A (ko) * 2018-03-29 2021-01-12 보드 오브 리전츠 더 유니버시티 오브 텍사스 시스템 전사 활성화 단백질의 이미다조피페라진 억제제
US10899769B2 (en) 2018-04-06 2021-01-26 Board Of Regents, The University Of Texas System Imidazopiperazinone inhibitors of transcription activating proteins
GB201908511D0 (en) 2019-06-13 2019-07-31 Adorx Therapeutics Ltd Hydroxamate compounds
WO2022072647A1 (en) * 2020-10-02 2022-04-07 Board Of Regents, The University Of Texas System Imidazopiperazine inhibitors of transcription activating proteins
IL301707A (en) * 2020-10-02 2023-05-01 Univ Texas Imidazopiperazine inhibitors of transcription-activating proteins
US20240228501A1 (en) * 2021-04-21 2024-07-11 Changchun Genescience Pharmaceutical Co., Ltd. Imidazole-containing condensed ring derivative, preparation method therefor, and application thereof in medicine

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JP4498922B2 (ja) 2002-07-09 2010-07-07 アクテリオン ファーマシューティカルズ リミテッド ７，８，９，１０−テトラヒドロ−６Ｈ−アゼピノ、６，７，８，９−テトラヒドロ−ピリドおよび２，３−ジヒドロ−２Ｈ−ピロロ［２，１−ｂ］−キナゾリノン誘導体
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CN101568542A (zh) 2009-10-28
KR20090106538A (ko) 2009-10-09
US8188082B2 (en) 2012-05-29
MA31002B1 (fr) 2009-12-01
EP2125823A1 (de) 2009-12-02
AU2007337659A1 (en) 2008-07-03
EP2125823B1 (de) 2012-02-15
ATE545647T1 (de) 2012-03-15
RU2009127842A (ru) 2011-01-27
CN101568542B (zh) 2013-03-27
CA2669561A1 (en) 2008-07-03
WO2008078291A1 (en) 2008-07-03
ES2380391T3 (es) 2012-05-11
BRPI0720522A2 (pt) 2014-01-07
JP2010513466A (ja) 2010-04-30
MX2009006553A (es) 2009-06-26
US20100093740A1 (en) 2010-04-15

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