NO20092181L - Azaadamantan-derivater og deres anvendelse som ligander for nikotin-acetylkolinreseptorer - Google Patents

Azaadamantan-derivater og deres anvendelse som ligander for nikotin-acetylkolinreseptorer

Info

Publication number
NO20092181L
NO20092181L NO20092181A NO20092181A NO20092181L NO 20092181 L NO20092181 L NO 20092181L NO 20092181 A NO20092181 A NO 20092181A NO 20092181 A NO20092181 A NO 20092181A NO 20092181 L NO20092181 L NO 20092181L
Authority
NO
Norway
Prior art keywords
nicotine
ligands
acetylcholine receptors
azaadamantane derivatives
compounds
Prior art date
Application number
NO20092181A
Other languages
English (en)
Inventor
Michael R Schrimpf
Kevin B Sippy
Geoff G Z Zhang
Rodger F Henry
Chih-Hung Lee
Diana L Nersesian
Jianguo Ji
Tao Li
Marc Scanio
Lei Shi
William H Bunnelle
Paul J Brackemeyer
Shuang Chen
Original Assignee
Abbvie Bahamas Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39594848&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20092181(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Bahamas Ltd filed Critical Abbvie Bahamas Ltd
Publication of NO20092181L publication Critical patent/NO20092181L/no

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
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  • Veterinary Medicine (AREA)
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  • Epidemiology (AREA)
  • Neurology (AREA)
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  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
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  • Gynecology & Obstetrics (AREA)
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Abstract

Oppfinnelsen relaterer seg ti forbindelser som er azaadamantanderivater, særlig eter- eller aminsubstituerte azaadamantanderivater og salter og prodmg derav, sammensetninger omfattende slike forbindelser, fremgangsmåter for å anvende slike forbindelser og sammensetninger, prosesser for å fremstille slike forbindelser, og intermediater oppnådd i løpet av slik prosess.
NO20092181A 2006-11-06 2009-06-08 Azaadamantan-derivater og deres anvendelse som ligander for nikotin-acetylkolinreseptorer NO20092181L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85699206P 2006-11-06 2006-11-06
US90814307P 2007-03-26 2007-03-26
US11/935,157 US8314119B2 (en) 2006-11-06 2007-11-05 Azaadamantane derivatives and methods of use
PCT/US2007/083687 WO2008058096A2 (en) 2006-11-06 2007-11-06 Azaadamantane derivatives and their uses as nicotinic acetylcholine receptors ligands

Publications (1)

Publication Number Publication Date
NO20092181L true NO20092181L (no) 2009-07-21

Family

ID=39594848

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NO20092181A NO20092181L (no) 2006-11-06 2009-06-08 Azaadamantan-derivater og deres anvendelse som ligander for nikotin-acetylkolinreseptorer

Country Status (29)

Country Link
US (3) US8314119B2 (no)
EP (1) EP2099795B1 (no)
JP (4) JP5275246B2 (no)
KR (4) KR20140054300A (no)
CN (1) CN103554107B (no)
AU (1) AU2007316480B2 (no)
BR (1) BRPI0718028A2 (no)
CA (1) CA2668962C (no)
CO (1) CO6210720A2 (no)
CR (2) CR10743A (no)
DK (1) DK2099795T3 (no)
DO (3) DOP2011000301A (no)
EC (1) ECSP099388A (no)
ES (1) ES2551117T3 (no)
HK (1) HK1133645A1 (no)
IL (2) IL198587A (no)
MX (2) MX340064B (no)
MY (1) MY148253A (no)
NO (1) NO20092181L (no)
NZ (4) NZ618134A (no)
PH (1) PH12013500745A1 (no)
PL (1) PL2099795T3 (no)
PT (1) PT2099795E (no)
RU (2) RU2450002C2 (no)
SG (1) SG176473A1 (no)
TW (1) TWI511729B (no)
UA (1) UA96961C2 (no)
WO (1) WO2008058096A2 (no)
ZA (3) ZA200903944B (no)

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US8383657B2 (en) 2007-12-21 2013-02-26 Abbott Laboratories Thiazolylidine urea and amide derivatives and methods of use thereof
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US8802693B1 (en) * 2011-03-09 2014-08-12 Abbvie Inc. Azaadamantane derivatives and methods of use
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BR112014007485B1 (pt) 2011-10-20 2022-05-31 Novartis Ag Métodos para prever responsividade terapêutica de um indivíduo a tratamento com um ativador do receptor de acetilcolina nicotínico alfa 7, e usos do referido ativador
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CA2894384C (en) 2012-12-11 2018-03-06 Novartis Ag Biomarker predictive of responsiveness to alpha 7 nicotinic acetylcholine receptor activator treatment
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