NO20092066L - Pyrrolderivater, fremgangsmate for fremstilling og terapeutisk anvendelse derav - Google Patents
Pyrrolderivater, fremgangsmate for fremstilling og terapeutisk anvendelse deravInfo
- Publication number
- NO20092066L NO20092066L NO20092066A NO20092066A NO20092066L NO 20092066 L NO20092066 L NO 20092066L NO 20092066 A NO20092066 A NO 20092066A NO 20092066 A NO20092066 A NO 20092066A NO 20092066 L NO20092066 L NO 20092066L
- Authority
- NO
- Norway
- Prior art keywords
- group
- preparation
- therapeutic use
- pyrrole derivatives
- optionally substituted
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000003233 pyrroles Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000006526 (C1-C2) alkyl group Chemical group 0.000 abstract 1
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
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- C07D317/58—Radicals substituted by nitrogen atoms
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Abstract
Det beskrives forbindelser med formel (I) der A representerer en eventuell substituert (Ci-Cå) alkylengruppe; en formel (II) gruppe der m = 0,1 eller 2 og p = 0 eller 1; Ri er hydrogen eller (C1-C2) alkyl; R2 er en eventuelt substituert (C3-C10) alkylgruppe, en eventuelt substituert, ikke-aromatisk (C3-C12) karbosyklisk rest, en heterosyklisk substituert eller ikke-substituert rest, en alkylen (C1-C3) substituert gruppe, en NR10R11 gruppe; R9 er en funksjonell gruppe eller en heterosyklisk rest. Videre beskrives fremstillingsmetoder og forbindelsenes anvendelse i terapi.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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FR0610202A FR2908766B1 (fr) | 2006-11-20 | 2006-11-20 | Derives de pyrrole,leur preparation et leur utilisation en therapeutique. |
PCT/FR2007/001888 WO2008068423A2 (fr) | 2006-11-20 | 2007-11-19 | Derives de pyrrole, leur preparation et leur utilisation en therapeutique. |
Publications (1)
Publication Number | Publication Date |
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NO20092066L true NO20092066L (no) | 2009-08-11 |
Family
ID=38521242
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20092066A NO20092066L (no) | 2006-11-20 | 2009-05-27 | Pyrrolderivater, fremgangsmate for fremstilling og terapeutisk anvendelse derav |
Country Status (27)
Country | Link |
---|---|
US (1) | US8044072B2 (no) |
EP (1) | EP2094656B1 (no) |
JP (1) | JP5210320B2 (no) |
KR (1) | KR20090080992A (no) |
CN (1) | CN101535250A (no) |
AR (1) | AR064596A1 (no) |
AT (1) | ATE520654T1 (no) |
AU (1) | AU2007330651A1 (no) |
BR (1) | BRPI0718962A2 (no) |
CA (1) | CA2669996A1 (no) |
CL (1) | CL2007003318A1 (no) |
CR (1) | CR10772A (no) |
DO (1) | DOP2009000105A (no) |
EA (1) | EA200970497A1 (no) |
EC (1) | ECSP099339A (no) |
FR (1) | FR2908766B1 (no) |
IL (1) | IL198481A0 (no) |
MA (1) | MA30996B1 (no) |
MX (1) | MX2009005366A (no) |
NO (1) | NO20092066L (no) |
PE (1) | PE20081495A1 (no) |
SV (1) | SV2009003265A (no) |
TN (1) | TN2009000166A1 (no) |
TW (1) | TW200829565A (no) |
UY (1) | UY30729A1 (no) |
WO (1) | WO2008068423A2 (no) |
ZA (1) | ZA200903865B (no) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2930939B1 (fr) * | 2008-05-09 | 2010-07-30 | Sanofi Aventis | Derives de pyrrole, leur preparation et leur application en therapeutique |
FR2930940B1 (fr) * | 2008-05-09 | 2011-02-11 | Sanofi Aventis | Derives de pyrrole, leur preparation et leur application en therapeutique |
CN102964304B (zh) * | 2012-09-28 | 2015-06-17 | 苏州大学 | 含吡唑烷酮结构的手性氨基氰化物的制备方法 |
AU2017297550B2 (en) | 2016-07-12 | 2019-07-11 | Guangdong Raynovent Biotech Co., Ltd. | Pyrrolidine derivative serving as PPAR agonist |
JP6969001B2 (ja) | 2017-12-21 | 2021-11-24 | 広東衆生睿創生物科技有限公司Guangdong Raynovent Biotech Co., Ltd. | Pparアゴニストとして用いられるピロリジン誘導体の非晶質及びその製造方法 |
EP3886854A4 (en) | 2018-11-30 | 2022-07-06 | Nuvation Bio Inc. | PYRROLE AND PYRAZOLE COMPOUNDS AND METHODS OF USE THERE |
Family Cites Families (6)
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AU2002319627A1 (en) * | 2001-07-20 | 2003-03-03 | Merck And Co., Inc. | Substituted imidazoles as cannabinoid receptor modulators |
FR2856683A1 (fr) * | 2003-06-25 | 2004-12-31 | Sanofi Synthelabo | Derives de 4-cyanopyrazole-3-carboxamide, leur preparation et leur application en therapeutique |
DK1756066T3 (da) * | 2004-05-28 | 2008-12-15 | Solvay Pharm Bv | Tetrasubstituerede imidazolderivater som canabinoid-CB1-receptormodulatorer med höj CB1/CB2-receptorundertypeselektivitet |
FR2874012B1 (fr) * | 2004-08-09 | 2008-08-22 | Sanofi Synthelabo | Derives de pyrrole, leur preparation et leur utlisation en therapeutique |
FR2881744B1 (fr) * | 2005-02-09 | 2007-04-27 | Sanofi Aventis Sa | Derives de n-[(4,5-diphenyl-2-thienyl)methyl]amine, leur preparation et leur application en therapeutique |
JP2008530179A (ja) * | 2005-02-16 | 2008-08-07 | ソルベイ・フアーマシユーチカルズ・ベー・ブイ | カンナビノイドcb2受容体モジュレーターとしての1h−イミダゾール誘導体 |
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- 2007-11-19 CN CNA2007800429161A patent/CN101535250A/zh active Pending
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Also Published As
Publication number | Publication date |
---|---|
DOP2009000105A (es) | 2009-05-31 |
CN101535250A (zh) | 2009-09-16 |
SV2009003265A (es) | 2010-02-05 |
MA30996B1 (fr) | 2009-12-01 |
CA2669996A1 (fr) | 2008-06-12 |
CR10772A (es) | 2009-07-23 |
IL198481A0 (en) | 2010-02-17 |
EP2094656B1 (fr) | 2011-08-17 |
CL2007003318A1 (es) | 2008-07-04 |
FR2908766A1 (fr) | 2008-05-23 |
JP2010510198A (ja) | 2010-04-02 |
ZA200903865B (en) | 2010-08-25 |
WO2008068423A3 (fr) | 2008-07-31 |
JP5210320B2 (ja) | 2013-06-12 |
TW200829565A (en) | 2008-07-16 |
TN2009000166A1 (fr) | 2010-10-18 |
FR2908766B1 (fr) | 2009-01-09 |
PE20081495A1 (es) | 2008-12-31 |
ATE520654T1 (de) | 2011-09-15 |
US8044072B2 (en) | 2011-10-25 |
ECSP099339A (es) | 2009-06-30 |
BRPI0718962A2 (pt) | 2013-12-17 |
AU2007330651A1 (en) | 2008-06-12 |
EA200970497A1 (ru) | 2009-10-30 |
WO2008068423A2 (fr) | 2008-06-12 |
AR064596A1 (es) | 2009-04-15 |
KR20090080992A (ko) | 2009-07-27 |
MX2009005366A (es) | 2009-06-08 |
UY30729A1 (es) | 2008-07-03 |
EP2094656A2 (fr) | 2009-09-02 |
US20090281116A1 (en) | 2009-11-12 |
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