ECSP099339A - Derivados de pirrol, su preparación y su utilización en terapéutica - Google Patents

Derivados de pirrol, su preparación y su utilización en terapéutica

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Publication number
ECSP099339A
ECSP099339A EC2009009339A ECSP099339A ECSP099339A EC SP099339 A ECSP099339 A EC SP099339A EC 2009009339 A EC2009009339 A EC 2009009339A EC SP099339 A ECSP099339 A EC SP099339A EC SP099339 A ECSP099339 A EC SP099339A
Authority
EC
Ecuador
Prior art keywords
substituted
group
unsubstituted
therapeutics
preparation
Prior art date
Application number
EC2009009339A
Other languages
English (en)
Inventor
Francis Barth
Christian Congy
Murielle Rinaldi-Carmona
Laurent Hortala
Original Assignee
Sanofi Aventis
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38521242&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP099339(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of ECSP099339A publication Critical patent/ECSP099339A/es

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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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Abstract

La invención tiene por objeto compuestos que responden a la fórmula (I) en la que A representa: un grupo alquileno(C1-C6) no sustituido o sustituido; un grupo Fórmula (II) con m = 0, 1 o 2 y p = 0 o 1; R1 representa hidrógeno o un alquilo(C1-C4); R2 representa: un grupo alquilo(C3-C10) no sustituido o sustituido; un radical carbocíclico no aromático de C3-C12, no sustituido o sustituido; un radical heterocíclico no sustituido o sustituido; un grupo alquileno(C1-C3) sustituido; un grupo NR10R11; R9 representa un grupo funcional o un radical heterocíclico; Procedimiento de preparación y aplicación en terapéutica.
EC2009009339A 2006-11-20 2009-05-18 Derivados de pirrol, su preparación y su utilización en terapéutica ECSP099339A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0610202A FR2908766B1 (fr) 2006-11-20 2006-11-20 Derives de pyrrole,leur preparation et leur utilisation en therapeutique.
PCT/FR2007/001888 WO2008068423A2 (fr) 2006-11-20 2007-11-19 Derives de pyrrole, leur preparation et leur utilisation en therapeutique.

Publications (1)

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ECSP099339A true ECSP099339A (es) 2009-06-30

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EC2009009339A ECSP099339A (es) 2006-11-20 2009-05-18 Derivados de pirrol, su preparación y su utilización en terapéutica

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FR2930939B1 (fr) * 2008-05-09 2010-07-30 Sanofi Aventis Derives de pyrrole, leur preparation et leur application en therapeutique
FR2930940B1 (fr) * 2008-05-09 2011-02-11 Sanofi Aventis Derives de pyrrole, leur preparation et leur application en therapeutique
CN102964304B (zh) * 2012-09-28 2015-06-17 苏州大学 含吡唑烷酮结构的手性氨基氰化物的制备方法
RU2711991C1 (ru) * 2016-07-12 2020-01-23 Гуандун Рейновент Биотек Ко., Лтд. Производные пирролидина в качестве агонистов ppar
RU2749056C1 (ru) 2017-12-21 2021-06-03 Гуандун Рэйновент Байотек Ко., Лтд. Аморфное производное пирролидина в качестве агониста ppar и способ его получения
US11034669B2 (en) 2018-11-30 2021-06-15 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof

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JP5210320B2 (ja) 2013-06-12
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JP2010510198A (ja) 2010-04-02
EP2094656B1 (fr) 2011-08-17
US20090281116A1 (en) 2009-11-12
PE20081495A1 (es) 2008-12-31
CN101535250A (zh) 2009-09-16
EA200970497A1 (ru) 2009-10-30
FR2908766A1 (fr) 2008-05-23
CR10772A (es) 2009-07-23
WO2008068423A2 (fr) 2008-06-12
ZA200903865B (en) 2010-08-25
TN2009000166A1 (fr) 2010-10-18
DOP2009000105A (es) 2009-05-31
EP2094656A2 (fr) 2009-09-02
CA2669996A1 (fr) 2008-06-12
AU2007330651A1 (en) 2008-06-12
BRPI0718962A2 (pt) 2013-12-17
MA30996B1 (fr) 2009-12-01
FR2908766B1 (fr) 2009-01-09
CL2007003318A1 (es) 2008-07-04
UY30729A1 (es) 2008-07-03
NO20092066L (no) 2009-08-11
US8044072B2 (en) 2011-10-25
ATE520654T1 (de) 2011-09-15
MX2009005366A (es) 2009-06-08
KR20090080992A (ko) 2009-07-27
SV2009003265A (es) 2010-02-05
IL198481A0 (en) 2010-02-17

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