ECSP077400A - Derivados de piridina, su preparación y su aplicación en terapéutica - Google Patents

Derivados de piridina, su preparación y su aplicación en terapéutica

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Publication number
ECSP077400A
ECSP077400A EC2007007400A ECSP077400A ECSP077400A EC SP077400 A ECSP077400 A EC SP077400A EC 2007007400 A EC2007007400 A EC 2007007400A EC SP077400 A ECSP077400 A EC SP077400A EC SP077400 A ECSP077400 A EC SP077400A
Authority
EC
Ecuador
Prior art keywords
group
therapeutics
preparation
application
piridine
Prior art date
Application number
EC2007007400A
Other languages
English (en)
Inventor
Francis Barth
Christian Congy
Murielle Rinaldi-Carmona
Philippe Pointeau
Lionel Barre
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of ECSP077400A publication Critical patent/ECSP077400A/es

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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Abstract

La presente invención tiene como objetivo compuestos que responden a la fórmula: en la que: Z representa un grupo N(R1)XR2, N(R1)COOR'2 o OCON(R1)R'2; X representa un grupo -CO-, -SO2-, -CON(R10)- o -CSN(R10)-; R1 representa un átomo de hidrógeno o un grupo alquilo de (C1-C4); R2 representa: un grupo alquilo de (C3-C10); un radical carbocíclico no aromático de (C3-C12); un radical heterocíclico; un fenilo no sustituido o sustituido; un alquileno de (C1-C2) sustituido con uno o dos sustituyentes idénticos o diferentes; R'2 representa un fenilo no sustituido o sustituido; R3 representa un átomo de hidrógeno o un grupo alquilo de (C1-C4), ciano, alcoximetilo de (C1-C4) o hidroximetilo. Procedimiento de preparación y aplicación en terapéutica.
EC2007007400A 2004-10-18 2007-04-17 Derivados de piridina, su preparación y su aplicación en terapéutica ECSP077400A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0411030A FR2876691B1 (fr) 2004-10-18 2004-10-18 Derives de pyridine, leur preparation, leur application en therapeutique
PCT/FR2005/002566 WO2006042955A1 (fr) 2004-10-18 2005-10-17 Derives de pyridine, leur preparation, leur application en therapeutique

Publications (1)

Publication Number Publication Date
ECSP077400A true ECSP077400A (es) 2007-05-30

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FR2899899A1 (fr) * 2006-04-14 2007-10-19 Sanofi Aventis Sa Derives d'aminomethyl pyridine, leur preparation et leur application en therapeutique
TW200815438A (en) * 2006-06-13 2008-04-01 Bayer Schering Pharma Ag Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
US7781593B2 (en) 2006-09-14 2010-08-24 Hoffmann-La Roche Inc. 5-phenyl-nicotinamide derivatives
FR2922209B1 (fr) * 2007-10-12 2010-06-11 Sanofi Aventis 5,6-DIARYLES PYRIDINES SUBSTITUES EN POSITION 2 et 3, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE.
AU2010247414B2 (en) 2009-05-15 2013-08-01 Novartis Ag Aryl pyridine as aldosterone synthase inhibitors
CN109476599A (zh) * 2016-07-29 2019-03-15 东丽株式会社 胍衍生物和其医药用途
WO2018159650A1 (ja) * 2017-02-28 2018-09-07 東レ株式会社 グアニジン誘導体及びその医薬用途

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FR2198737B1 (es) * 1972-09-13 1975-11-28 Serdex
US5686470A (en) * 1995-02-10 1997-11-11 Weier; Richard M. 2, 3-substituted pyridines for the treatment of inflammation
JP2004517870A (ja) * 2001-01-02 2004-06-17 藤沢薬品工業株式会社 シクロオキシゲナーゼ阻害剤
CA2479744A1 (en) * 2002-03-28 2003-10-09 Paul E. Finke Substituted 2,3-diphenyl pyridines
FR2838438A1 (fr) * 2002-04-11 2003-10-17 Sanofi Synthelabo Derives de diphenylpyridine,leur preparation, les compositions pharmaceutiques en contenant
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PE20060584A1 (es) 2006-08-18
IL182385A0 (en) 2007-07-24
EA200700891A1 (ru) 2007-08-31
BRPI0516926A (pt) 2008-09-23
TW200628450A (en) 2006-08-16
MX2007004482A (es) 2007-06-13
JP2008516934A (ja) 2008-05-22
US20080021070A1 (en) 2008-01-24
NZ554952A (en) 2009-08-28
EP1805143A1 (fr) 2007-07-11
CA2582778A1 (fr) 2006-04-27
TNSN07114A1 (fr) 2008-06-02
CN101039912A (zh) 2007-09-19
KR20070063008A (ko) 2007-06-18
NO20072454L (no) 2007-05-14
AU2005296959A1 (en) 2006-04-27
FR2876691B1 (fr) 2006-12-29
MA29016B1 (fr) 2007-11-01
UY29163A1 (es) 2006-04-28
WO2006042955A1 (fr) 2006-04-27
AR051221A1 (es) 2006-12-27
FR2876691A1 (fr) 2006-04-21

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