BRPI0516926A - derivados de piridina, a respectiva preparação, a respectiva aplicação em terapêutica - Google Patents

derivados de piridina, a respectiva preparação, a respectiva aplicação em terapêutica

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Publication number
BRPI0516926A
BRPI0516926A BRPI0516926-7A BRPI0516926A BRPI0516926A BR PI0516926 A BRPI0516926 A BR PI0516926A BR PI0516926 A BRPI0516926 A BR PI0516926A BR PI0516926 A BRPI0516926 A BR PI0516926A
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Brazil
Prior art keywords
preparation
group
pyridine derivatives
therapeutic
application
Prior art date
Application number
BRPI0516926-7A
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English (en)
Inventor
Lionel Barre
Francis Barth
Christian Congy
Murielle Rinaldi-Carmona
Philippe Pointeau
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Sanofi Aventis
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Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of BRPI0516926A publication Critical patent/BRPI0516926A/pt

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Abstract

DERIVADOS DE PIRIDINA, A RESPECTIVA PREPARAçãO, A RESPECTIVA APLICAçãO EM TERAPêUTICA. A presente invenção refere-se a compostos correspondentes à fórmula (1), na qual: - Z representa um grupo N(R~ 1~)XR~ 2~, N(R~ 1~)COOR'~ 2~ ou OCON(R~ 1~)R'2; - X representa um grupo -CO-, -SO~ 2~, -CON(R~ 10~)- ou -CSN(R~ 10~)-; - R~ 1~ representa um átomo de hidrogênio ou um grupo (C~ 1~-C~ 4~)alquila; - R~ 2~ representa:um grupo (C~ 3~-C~ 10~)alquila; . um radical carbocíclico não-aromático em (C~ 3~- C~ 12~); um radical heterocíclico; . um fenila não-substituido ou substituído;-um (C~ 1~-C~ 2~) alquileno substituído por um ou dois substituintes idênticos ou diferentes; - R'~ 2~ representa um fenila não-substituído ou substituído; - R~ 3~ representa um átomo de hidrogênio ou um grupo (C~ 1~-C~ 4~alquila, ciano, (C~ 1~-C~ 4~)alcoximetila ou hidroximetila. Processo de preparação e aplicação em terapêutica.
BRPI0516926-7A 2004-10-18 2005-10-17 derivados de piridina, a respectiva preparação, a respectiva aplicação em terapêutica BRPI0516926A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0411030A FR2876691B1 (fr) 2004-10-18 2004-10-18 Derives de pyridine, leur preparation, leur application en therapeutique
PCT/FR2005/002566 WO2006042955A1 (fr) 2004-10-18 2005-10-17 Derives de pyridine, leur preparation, leur application en therapeutique

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US (1) US20080021070A1 (pt)
EP (1) EP1805143A1 (pt)
JP (1) JP2008516934A (pt)
KR (1) KR20070063008A (pt)
CN (1) CN101039912A (pt)
AR (1) AR051221A1 (pt)
AU (1) AU2005296959A1 (pt)
BR (1) BRPI0516926A (pt)
CA (1) CA2582778A1 (pt)
EA (1) EA200700891A1 (pt)
EC (1) ECSP077400A (pt)
FR (1) FR2876691B1 (pt)
IL (1) IL182385A0 (pt)
MA (1) MA29016B1 (pt)
MX (1) MX2007004482A (pt)
NO (1) NO20072454L (pt)
NZ (1) NZ554952A (pt)
PE (1) PE20060584A1 (pt)
TN (1) TNSN07114A1 (pt)
TW (1) TW200628450A (pt)
UY (1) UY29163A1 (pt)
WO (1) WO2006042955A1 (pt)

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FR2899899A1 (fr) * 2006-04-14 2007-10-19 Sanofi Aventis Sa Derives d'aminomethyl pyridine, leur preparation et leur application en therapeutique
TW200815438A (en) * 2006-06-13 2008-04-01 Bayer Schering Pharma Ag Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
US7781593B2 (en) 2006-09-14 2010-08-24 Hoffmann-La Roche Inc. 5-phenyl-nicotinamide derivatives
FR2922209B1 (fr) * 2007-10-12 2010-06-11 Sanofi Aventis 5,6-DIARYLES PYRIDINES SUBSTITUES EN POSITION 2 et 3, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE.
SI2429995T1 (sl) 2009-05-15 2014-05-30 Novartis Ag Arilpiridini kot inhibitorji aldosteron sintaze
US10662156B2 (en) 2016-07-29 2020-05-26 Toray Industries, Inc. Guanidine derivative and medical use thereof
WO2018159650A1 (ja) * 2017-02-28 2018-09-07 東レ株式会社 グアニジン誘導体及びその医薬用途

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FR2198737B1 (pt) * 1972-09-13 1975-11-28 Serdex
US5686470A (en) * 1995-02-10 1997-11-11 Weier; Richard M. 2, 3-substituted pyridines for the treatment of inflammation
CA2433623A1 (en) * 2001-01-02 2002-07-18 Fujisawa Pharmaceutical Co., Ltd. Pyridine derivatives useful as cyclooxygenase inhibitor
CA2479744A1 (en) * 2002-03-28 2003-10-09 Paul E. Finke Substituted 2,3-diphenyl pyridines
FR2838439B1 (fr) * 2002-04-11 2005-05-20 Sanofi Synthelabo Derives de terphenyle, leur preparation, les compositions pharmaceutqiues en contenant
FR2838438A1 (fr) * 2002-04-11 2003-10-17 Sanofi Synthelabo Derives de diphenylpyridine,leur preparation, les compositions pharmaceutiques en contenant

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FR2876691B1 (fr) 2006-12-29
EP1805143A1 (fr) 2007-07-11
NZ554952A (en) 2009-08-28
AU2005296959A1 (en) 2006-04-27
TNSN07114A1 (fr) 2008-06-02
CN101039912A (zh) 2007-09-19
KR20070063008A (ko) 2007-06-18
FR2876691A1 (fr) 2006-04-21
ECSP077400A (es) 2007-05-30
NO20072454L (no) 2007-05-14
JP2008516934A (ja) 2008-05-22
IL182385A0 (en) 2007-07-24
WO2006042955A1 (fr) 2006-04-27
PE20060584A1 (es) 2006-08-18
MA29016B1 (fr) 2007-11-01
UY29163A1 (es) 2006-04-28
MX2007004482A (es) 2007-06-13
US20080021070A1 (en) 2008-01-24
CA2582778A1 (fr) 2006-04-27
TW200628450A (en) 2006-08-16
EA200700891A1 (ru) 2007-08-31
AR051221A1 (es) 2006-12-27

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