NO20091625L - Polymorf B pa N-(2-fluoro-5-[3-(tiopen-2-karbonyl)-pyrazolo[1,5-A]pyrimidin-7-yl]-fenyl)-N-metylacetamid - Google Patents

Polymorf B pa N-(2-fluoro-5-[3-(tiopen-2-karbonyl)-pyrazolo[1,5-A]pyrimidin-7-yl]-fenyl)-N-metylacetamid

Info

Publication number
NO20091625L
NO20091625L NO20091625A NO20091625A NO20091625L NO 20091625 L NO20091625 L NO 20091625L NO 20091625 A NO20091625 A NO 20091625A NO 20091625 A NO20091625 A NO 20091625A NO 20091625 L NO20091625 L NO 20091625L
Authority
NO
Norway
Prior art keywords
polymorph
pyrazolo
pyrimidin
fluoro
carbonyl
Prior art date
Application number
NO20091625A
Other languages
English (en)
Other versions
NO342008B1 (no
Inventor
Antonio Guglietta
Luis Anglada
Albert Palomer
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37789824&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20091625(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of NO20091625L publication Critical patent/NO20091625L/no
Publication of NO342008B1 publication Critical patent/NO342008B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Det beskrives en ny polymorf av N-{2-f[uor-5-[3-(tiofen-2-karbonyl)-pyrazolo[l,5-a]pyrimidin-7-yl-fenyl}-N-metyl-acetarnid. Videre beskrives det fremgangsmåter for fremstilling av polymorfen, dens anvendelse som et medikament, dens bruk ved fremstilling av et medikament, og farmasøytiske preparater inneholdende den nye polymorf.
NO20091625A 2006-10-11 2009-04-23 Polymorf B av polymorf B av N-{2-fluor-5-[3-(tiofen-2-karbonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-fenyl)-N-metyl-acetamid NO342008B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85074306P 2006-10-11 2006-10-11
EP06122138A EP1918290A1 (en) 2006-10-11 2006-10-11 Polymorph B of N-{2-Fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a] pyrimidin-7-yl]-phenyl}-N-methyl-acetamide
PCT/EP2007/060797 WO2008043800A1 (en) 2006-10-11 2007-10-10 Polymorph b of n-{2-fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a] pyrimidin-7-yl]-phenyl}-n-methyl-acetamide

Publications (2)

Publication Number Publication Date
NO20091625L true NO20091625L (no) 2009-05-07
NO342008B1 NO342008B1 (no) 2018-03-12

Family

ID=37789824

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091625A NO342008B1 (no) 2006-10-11 2009-04-23 Polymorf B av polymorf B av N-{2-fluor-5-[3-(tiofen-2-karbonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-fenyl)-N-metyl-acetamid

Country Status (21)

Country Link
US (2) US8039476B2 (no)
EP (2) EP1918290A1 (no)
JP (1) JP5171831B2 (no)
KR (1) KR101418624B1 (no)
CN (1) CN101622257B (no)
AR (1) AR063231A1 (no)
AU (1) AU2007306319B2 (no)
BR (1) BRPI0717833A2 (no)
CA (1) CA2666653C (no)
CL (1) CL2007002928A1 (no)
DK (1) DK2081935T3 (no)
ES (1) ES2637137T3 (no)
MX (1) MX2009003571A (no)
NO (1) NO342008B1 (no)
PL (1) PL2081935T3 (no)
PT (1) PT2081935T (no)
RU (1) RU2413729C2 (no)
SI (1) SI2081935T1 (no)
TW (1) TWI391392B (no)
UY (1) UY30637A1 (no)
WO (1) WO2008043800A1 (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1921079A1 (en) * 2006-11-08 2008-05-14 Ferrer Internacional, S.A. Amorphous form of N-{2-Fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a] pyrimidin-7-yl]-phenyl}-N-methyl-acetamide
JP5149376B2 (ja) * 2008-03-31 2013-02-20 京セラ株式会社 太陽電池素子及び太陽電池モジュール
IT1391113B1 (it) * 2008-09-30 2011-11-18 Dipharma Francis Srl Procedimento per la preparazione di azelnidipina cristallina

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US399621A (en) * 1889-03-12 Canning-house truck
US6399621B1 (en) * 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
CZ2002783A3 (cs) * 1999-09-02 2004-01-14 Neurocrine Biosciences, Inc. Polymorfy N-methyl-N-[3-[3-(2-Thienylkarbonyl)pyrazol-[1,5-alfa]-pyrimidin-7-yl]fenyl]acetamid a prostředky a způsoby s tím související
DE60309332T2 (de) * 2002-08-26 2007-05-24 Neurocrine Biosciences, Inc., San Diego POLYMORPH VON N-METHYL-N-(3- 3-i2-THIENYLCARBONYLö-PYRAZOL-i1,5-ALPHAö-PYRIMIDIN-7-YL PHENYL)ACETAMID UND ZUSAMMENSETZUNGEN SOWIE VERFAHREN HIERZU
WO2006044903A1 (en) * 2004-10-18 2006-04-27 Neurocrine Biosciences, Inc. HYDRATE OF N-METHYL-N-(3-{3-[2-THIENYLCARBONYL]-PYRAZOL-[1,5-α]- PYRAMIDIN-7-YL}PHENYL)ACETAMIDE AND PROCESSES AND METHODS RELATED THERETO
EP1736475A1 (en) * 2005-06-21 2006-12-27 Ferrer Internacional, S.A. Halogenated pyrazolo[1,5-a]pyrimidines, processes, uses, compositions and intermediates

Also Published As

Publication number Publication date
WO2008043800A1 (en) 2008-04-17
JP5171831B2 (ja) 2013-03-27
ES2637137T3 (es) 2017-10-11
EP2081935B1 (en) 2017-05-24
US8273753B2 (en) 2012-09-25
TWI391392B (zh) 2013-04-01
AR063231A1 (es) 2009-01-14
JP2010505914A (ja) 2010-02-25
UY30637A1 (es) 2008-05-02
US20110224234A1 (en) 2011-09-15
EP2081935A1 (en) 2009-07-29
RU2009117716A (ru) 2010-11-20
BRPI0717833A2 (pt) 2014-06-10
KR101418624B1 (ko) 2014-07-15
RU2413729C2 (ru) 2011-03-10
AU2007306319A1 (en) 2008-04-17
SI2081935T1 (sl) 2017-12-29
MX2009003571A (es) 2009-04-14
US20100087451A1 (en) 2010-04-08
KR20090077796A (ko) 2009-07-15
CL2007002928A1 (es) 2008-05-09
CN101622257B (zh) 2013-03-27
TW200827360A (en) 2008-07-01
EP1918290A1 (en) 2008-05-07
AU2007306319B2 (en) 2012-12-06
NO342008B1 (no) 2018-03-12
PT2081935T (pt) 2017-08-29
PL2081935T3 (pl) 2018-04-30
CA2666653C (en) 2014-12-30
CA2666653A1 (en) 2008-04-17
US8039476B2 (en) 2011-10-18
DK2081935T3 (en) 2017-09-04
CN101622257A (zh) 2010-01-06

Similar Documents

Publication Publication Date Title
TW200745121A (en) Chemical compound
EA200801998A1 (ru) ПИРИДИН[3,4-b]ПИРАЗИНОНЫ
NZ599008A (en) 2-amino-5, 5-difluoro-5, 6-dihydro-4h-oxazines as bace 1 and/or bace 2 inhibitors
BRPI0408990A (pt) derivados de pirimidin-4-ona e sua utilização como moduladores da p38-cinase
MX2010006436A (es) Derivados peptidos mimeticos de eritropoyetina y sus sales farmaceuticas, su preparacion y usos.
ATE496021T1 (de) Kristalline formen von (-)-(1r,2r)-3-(3- dimethylamino-1-ethyl-2-methylpropyl)- phenolhydrochlorid zur verwendung als aktivstoff in pharmazeutischen zubereitungen
NZ593295A (en) Preparation method of dihydroindene amide compounds, their pharmaceutical compositions containing compounds thereof and use as protein kinase inhibitor
EA201170741A1 (ru) Производные n-{[(1r,4s,6r)-3-(2-пиридинилкарбонил)-3-азабицикло[4.1.0]гепт-4-ил]метил}-2-гетероариламина и их применения
UY30183A1 (es) Derivados de quinolina
TW200745111A (en) New compounds
NO20080186L (no) Heterosykliske aspartylproteaseinhibitorer, fremstilling og anvendelse derav
BR122013028012B8 (pt) composto de ciclopentano de pirimidila hidroxilado e metoxilado, sua composição farmacêutica e seu método de preparação
WO2007050587A3 (en) Therapeutic compositions and methods
BRPI0406762A (pt) Derivados de n-(1-benzil-2-oxo-2-(1-piperazinil)etil)-1-piperidincarb oxamida e compostos relacionados como antagonistas de cgrp, para tratamento de dores de cabeça
JO2770B1 (en) Organic compounds
TW200639156A (en) New compounds
NO20061575L (no) Fremgangsmate for fremstilling av renzapride og mellomprodukter derav
CY1109366T1 (el) Υποκατεστημενες ενωσεις 1,4,8-τριαζασπειρο[4.5]δεκαν-2-ονης
DK1869038T3 (da) Substituerede 5,6,7,8-tetrahydro-imidazol[1,2-a]pyridin-2-ylamin-forbindelser og deres anvendelse til fremstilling af lægemidler
NO20091625L (no) Polymorf B pa N-(2-fluoro-5-[3-(tiopen-2-karbonyl)-pyrazolo[1,5-A]pyrimidin-7-yl]-fenyl)-N-metylacetamid
TW200626581A (en) Compounds, compositions containing them, preparation thereof and uses thereof
NO20084177L (no) Substituerte Imidazo[2,1-B]thiazolforbindelser og deres anvendelse for produksjon av legemidler
DE602006009556D1 (de) Chinolin-derivate zur behandlung von mglur5-rezeptor-vermittelten erkrankungen
NO20070550L (no) Fremgangsmate for fremstilling av pyrrolotriazinforbindelser
TW200942529A (en) Pyrrolidinyl derivatives and uses thereof

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees