NO20084703L - Triazolopyrazinforbindelser nyttige for behandling av degenerative og inflammatoriske sykdommer - Google Patents
Triazolopyrazinforbindelser nyttige for behandling av degenerative og inflammatoriske sykdommerInfo
- Publication number
- NO20084703L NO20084703L NO20084703A NO20084703A NO20084703L NO 20084703 L NO20084703 L NO 20084703L NO 20084703 A NO20084703 A NO 20084703A NO 20084703 A NO20084703 A NO 20084703A NO 20084703 L NO20084703 L NO 20084703L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- degenerative
- inflammatory diseases
- compounds useful
- triazolopyrazine
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Nye [1,2,4]triazolo[1,5-a]pyrazin-forbindelser er beskrevet som har en formel representert ved den følgende (formel I). Forbindelsene kan fremstilles som farmasøytiske preparater og kan anvendes for forebygging og behandling av en rekke lidelser hos pattedyr omfattende mennesker, omfattende som ikke begrensende eksempler, artritt, inflammasjon og andre. (I)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80355206P | 2006-05-31 | 2006-05-31 | |
US93176307P | 2007-05-25 | 2007-05-25 | |
US93176407P | 2007-05-25 | 2007-05-25 | |
US93184407P | 2007-05-25 | 2007-05-25 | |
US93210007P | 2007-05-29 | 2007-05-29 | |
PCT/EP2007/055246 WO2007138072A2 (en) | 2006-05-31 | 2007-05-30 | Triazolopyrazine compounds useful for the treatment of degenerative & inflammatory diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20084703L true NO20084703L (no) | 2009-02-19 |
Family
ID=38618932
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20084703A NO20084703L (no) | 2006-05-31 | 2008-11-10 | Triazolopyrazinforbindelser nyttige for behandling av degenerative og inflammatoriske sykdommer |
Country Status (20)
Country | Link |
---|---|
US (3) | US7501411B2 (no) |
JP (1) | JP2009538877A (no) |
KR (1) | KR20090026288A (no) |
AT (1) | ATE465164T1 (no) |
AU (1) | AU2007267121A1 (no) |
BR (1) | BRPI0712531A2 (no) |
CA (1) | CA2653506A1 (no) |
CR (1) | CR10458A (no) |
DE (1) | DE602007006010D1 (no) |
DK (1) | DK2029602T3 (no) |
EA (1) | EA200870592A1 (no) |
EC (1) | ECSP088923A (no) |
HR (1) | HRP20100378T1 (no) |
IL (1) | IL195033A0 (no) |
MX (1) | MX2008015057A (no) |
NI (1) | NI200800299A (no) |
NO (1) | NO20084703L (no) |
NZ (1) | NZ573015A (no) |
PT (1) | PT2029602E (no) |
WO (1) | WO2007138072A2 (no) |
Families Citing this family (38)
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CN102924458B (zh) | 2004-04-02 | 2014-11-05 | Osi制药有限责任公司 | 6,6-双环取代的杂双环蛋白激酶抑制剂 |
US7893058B2 (en) * | 2006-05-15 | 2011-02-22 | Janssen Pharmaceutica Nv | Imidazolopyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
EA200870592A1 (ru) * | 2006-05-31 | 2009-08-28 | Галапагос Н.В. | Триазолопиразиновые соединения, пригодные для лечения дегенеративных и воспалительных заболеваний |
WO2008065198A1 (en) | 2006-12-01 | 2008-06-05 | Galapagos N.V. | Triazolopyridine compounds useful for the treatment of degenerative & inflammatory diseases |
WO2008138843A1 (en) | 2007-05-10 | 2008-11-20 | Galapagos N.V. | Imidazopyridines and triazolopyrimidines useful for the treatment of joint degenerative & inflammatory diseases |
US8148369B2 (en) | 2007-05-10 | 2012-04-03 | Janssen Pharmaceutica Nv | Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
DE102008035209A1 (de) | 2008-07-29 | 2010-02-04 | Bayer Schering Pharma Aktiengesellschaft | Triazolotriazine und Triazolopyrazine und ihre Verwendung |
DE102007060172A1 (de) | 2007-12-13 | 2009-06-25 | Bayer Healthcare Ag | Triazolotriazine und Triazolopyrazine und ihre Verwendung |
AR071619A1 (es) * | 2008-05-07 | 2010-06-30 | Galapagos Nv | Compuestos de pirazina fusionados utiles para el tratamiento de enfermedades degenerativas e inflamatorias y composiciones farmaceuticas que los contienen. |
DE102008023801A1 (de) | 2008-05-15 | 2009-11-19 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Imidazo- und Triazolopyrimidine, Imidazo- und Pyrazolopyrazine und Imidazotriazine |
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TW201120043A (en) * | 2009-11-05 | 2011-06-16 | Galapagos Nv | Fused pyrazine compounds as their salts, useful for the treatment of degenerative and inflammatory diseases |
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2007
- 2007-05-30 EA EA200870592A patent/EA200870592A1/ru unknown
- 2007-05-30 PT PT07729660T patent/PT2029602E/pt unknown
- 2007-05-30 KR KR1020087030751A patent/KR20090026288A/ko not_active Application Discontinuation
- 2007-05-30 AU AU2007267121A patent/AU2007267121A1/en not_active Abandoned
- 2007-05-30 JP JP2009512585A patent/JP2009538877A/ja not_active Abandoned
- 2007-05-30 MX MX2008015057A patent/MX2008015057A/es active IP Right Grant
- 2007-05-30 AT AT07729660T patent/ATE465164T1/de active
- 2007-05-30 CA CA002653506A patent/CA2653506A1/en not_active Abandoned
- 2007-05-30 DE DE602007006010T patent/DE602007006010D1/de active Active
- 2007-05-30 US US11/809,294 patent/US7501411B2/en not_active Expired - Fee Related
- 2007-05-30 BR BRPI0712531-3A patent/BRPI0712531A2/pt not_active IP Right Cessation
- 2007-05-30 WO PCT/EP2007/055246 patent/WO2007138072A2/en active Application Filing
- 2007-05-30 DK DK07729660.6T patent/DK2029602T3/da active
- 2007-05-30 NZ NZ573015A patent/NZ573015A/en not_active IP Right Cessation
-
2008
- 2008-10-30 IL IL195033A patent/IL195033A0/en unknown
- 2008-11-10 NO NO20084703A patent/NO20084703L/no not_active Application Discontinuation
- 2008-11-20 NI NI200800299A patent/NI200800299A/es unknown
- 2008-11-25 CR CR10458A patent/CR10458A/es unknown
- 2008-11-28 EC EC2008008923A patent/ECSP088923A/es unknown
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2009
- 2009-03-08 US US12/399,979 patent/US7915256B2/en not_active Expired - Fee Related
-
2010
- 2010-07-06 HR HR20100378T patent/HRP20100378T1/hr unknown
-
2011
- 2011-01-09 US US12/987,129 patent/US20110178067A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MX2008015057A (es) | 2008-12-10 |
DK2029602T3 (da) | 2010-08-09 |
ECSP088923A (es) | 2009-01-30 |
AU2007267121A1 (en) | 2007-12-06 |
NZ573015A (en) | 2010-11-26 |
CR10458A (es) | 2009-02-26 |
US20100298300A1 (en) | 2010-11-25 |
WO2007138072A2 (en) | 2007-12-06 |
US20080090818A1 (en) | 2008-04-17 |
KR20090026288A (ko) | 2009-03-12 |
IL195033A0 (en) | 2009-08-03 |
EA200870592A1 (ru) | 2009-08-28 |
HRP20100378T1 (hr) | 2010-08-31 |
DE602007006010D1 (de) | 2010-06-02 |
US20110178067A1 (en) | 2011-07-21 |
CA2653506A1 (en) | 2007-12-06 |
PT2029602E (pt) | 2010-07-08 |
ATE465164T1 (de) | 2010-05-15 |
WO2007138072A3 (en) | 2008-02-14 |
US7501411B2 (en) | 2009-03-10 |
BRPI0712531A2 (pt) | 2012-12-25 |
NI200800299A (es) | 2010-05-25 |
US7915256B2 (en) | 2011-03-29 |
JP2009538877A (ja) | 2009-11-12 |
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