NO20083582L - Pyridin-2-karboksamide derivater - Google Patents
Pyridin-2-karboksamide derivaterInfo
- Publication number
- NO20083582L NO20083582L NO20083582A NO20083582A NO20083582L NO 20083582 L NO20083582 L NO 20083582L NO 20083582 A NO20083582 A NO 20083582A NO 20083582 A NO20083582 A NO 20083582A NO 20083582 L NO20083582 L NO 20083582L
- Authority
- NO
- Norway
- Prior art keywords
- pyridine
- carboxamide derivatives
- derivatives
- useful
- general formula
- Prior art date
Links
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Abstract
Foreliggende oppfinnelse angår nye pyridin-2-karboksyamid-derivater med den generelle formel (I), som er anvendelige som metabotrope glutamatreseptor-antagonister: hvor Y, Z, R1, R2 og R3 er som definert i beskrivelsen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06110086 | 2006-02-17 | ||
PCT/EP2007/051165 WO2007093542A1 (en) | 2006-02-17 | 2007-02-07 | Pyridine-2-carboxamide derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20083582L true NO20083582L (no) | 2008-11-12 |
Family
ID=37930432
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20083582A NO20083582L (no) | 2006-02-17 | 2008-08-19 | Pyridin-2-karboksamide derivater |
Country Status (15)
Country | Link |
---|---|
US (1) | US7951824B2 (no) |
EP (1) | EP1987003A1 (no) |
JP (1) | JP4975763B2 (no) |
KR (1) | KR101069106B1 (no) |
CN (1) | CN101384554B (no) |
AR (1) | AR059512A1 (no) |
AU (1) | AU2007216565A1 (no) |
BR (1) | BRPI0707949A2 (no) |
CA (1) | CA2640582A1 (no) |
IL (1) | IL193175A0 (no) |
NO (1) | NO20083582L (no) |
RU (1) | RU2427580C2 (no) |
TW (1) | TWI360547B (no) |
WO (1) | WO2007093542A1 (no) |
ZA (1) | ZA200806809B (no) |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR063028A1 (es) | 2006-10-06 | 2008-12-23 | Banyu Pharma Co Ltd | Derivados heterociclicos de piridin-2-carboxamida activadores de glucoquinasas, utiles para el tratamiento de diabetes y obesidad y composiciones farmaceuticas que los contienen. |
CL2008001933A1 (es) | 2007-06-29 | 2009-09-25 | Millennium Pharm Inc | Compuestos derivados de pirimidina, inhibidores de la raf quinasa; compuestos intermediarios; procedimiento de preparacion; composicion farmaceutica; y su uso para tratar trastornos proliferativos, cardiacos, neurodegenerativos, inflamatorios, oseos, inmunologicos enfermedad viral, entre otros. |
BRPI0916576A2 (pt) * | 2008-08-04 | 2017-06-27 | Chdi Inc | pelo menos uma entidade química, composição farmacêutica, e, método para tratar uma condição ou distúrbio. |
EP2198710A1 (de) | 2008-12-19 | 2010-06-23 | Bayer CropScience AG | Verwendung von 5-Pyridin-4yl-(1,3)Thiazole zur Bekämpfung phytopathogener Pilze |
WO2010100050A1 (en) * | 2009-03-05 | 2010-09-10 | F. Hoffmann-La Roche Ag | Pyridine-2-yl-carboxylic acid amides |
US8618307B2 (en) | 2009-09-16 | 2013-12-31 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
WO2011035174A1 (en) * | 2009-09-17 | 2011-03-24 | Vanderbilt University | Substituted heteroarylamine carboxamide analogs as mglur5 negative allosteric modulators and methods of making and using the same |
SG182534A1 (en) | 2010-01-25 | 2012-08-30 | Chdi Foundation Inc | Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
US8410117B2 (en) | 2010-03-26 | 2013-04-02 | Hoffmann-La Roche Inc. | Imidazopyrimidine derivatives |
US10703722B2 (en) | 2010-04-27 | 2020-07-07 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
AU2011248579A1 (en) | 2010-04-27 | 2012-11-29 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
WO2011139489A2 (en) | 2010-04-27 | 2011-11-10 | Calcimedica Inc. | Compounds that modulate intracellular calcium |
MX2012013031A (es) * | 2010-05-12 | 2012-12-17 | Univ Vanderbilt | Potenciadores alostericos mglur4 de sulfona heterociclica, composiciones y metodos para tratar disfuncion neurologica. |
US20110294879A1 (en) * | 2010-05-28 | 2011-12-01 | Xenoport, Inc. | Method of treatment of fragile x syndrome, down's syndrome, autism and related disorders |
US9079891B2 (en) | 2010-08-27 | 2015-07-14 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
WO2012170931A2 (en) | 2011-06-10 | 2012-12-13 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
MX364378B (es) | 2011-08-30 | 2019-01-21 | Chdi Foundation Inc | Inhibidores de la quinurenina-3-monooxigenasa, sus composiciones farmaceuticas y metodos para uso. |
EP2751086A4 (en) | 2011-08-30 | 2015-09-16 | Chdi Foundation Inc | KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHOD OF USE THEREOF |
WO2013059677A1 (en) | 2011-10-19 | 2013-04-25 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
CN103360376A (zh) * | 2013-07-16 | 2013-10-23 | 临海市联盛化学有限公司 | 一种制备17β-HSD1抑制剂的方法 |
MX2017000779A (es) | 2014-07-17 | 2017-07-27 | Chdi Foundation Inc | Metodos y composiciones para el tratamiento de trastornos relacionados con el vih. |
DK3778595T3 (da) | 2015-02-27 | 2021-10-18 | Calcimedica Inc | Pancreatitisbehandling |
EP3331525B1 (en) | 2015-08-07 | 2020-10-07 | Calcimedica, Inc. | Use of crac channel inhibitors for the treatment of stroke and traumatic brain injury |
US20190053492A1 (en) | 2016-03-16 | 2019-02-21 | Bayer Cropscience Aktiengesellschaft | Substituted pyridine compounds as pesticides |
EP3284739A1 (de) | 2017-07-19 | 2018-02-21 | Bayer CropScience Aktiengesellschaft | Substituierte (het)arylverbindungen als schädlingsbekämpfungsmittel |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
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EP0321115B1 (en) | 1987-12-14 | 1991-08-14 | Sawai Pharmaceutical Co., Ltd. | Carboxamide derivatives having tetrazole and thiazole rings and their use |
AU3571997A (en) | 1996-08-01 | 1998-02-25 | Warner-Lambert Company | Novel glutamate receptor antagonists: fused cycloalkyl quinoxalinediones |
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-
2007
- 2007-01-30 US US11/699,786 patent/US7951824B2/en not_active Expired - Fee Related
- 2007-02-07 WO PCT/EP2007/051165 patent/WO2007093542A1/en active Application Filing
- 2007-02-07 AU AU2007216565A patent/AU2007216565A1/en not_active Abandoned
- 2007-02-07 CN CN2007800058848A patent/CN101384554B/zh not_active Expired - Fee Related
- 2007-02-07 JP JP2008554740A patent/JP4975763B2/ja not_active Expired - Fee Related
- 2007-02-07 BR BRPI0707949-4A patent/BRPI0707949A2/pt not_active IP Right Cessation
- 2007-02-07 RU RU2008133321/04A patent/RU2427580C2/ru not_active IP Right Cessation
- 2007-02-07 KR KR1020087020073A patent/KR101069106B1/ko not_active IP Right Cessation
- 2007-02-07 EP EP20070704421 patent/EP1987003A1/en not_active Withdrawn
- 2007-02-07 CA CA002640582A patent/CA2640582A1/en not_active Abandoned
- 2007-02-13 TW TW096105167A patent/TWI360547B/zh not_active IP Right Cessation
- 2007-02-15 AR ARP070100650A patent/AR059512A1/es unknown
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2008
- 2008-07-31 IL IL193175A patent/IL193175A0/en unknown
- 2008-08-06 ZA ZA200806809A patent/ZA200806809B/xx unknown
- 2008-08-19 NO NO20083582A patent/NO20083582L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
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RU2008133321A (ru) | 2010-03-27 |
AU2007216565A1 (en) | 2007-08-23 |
US7951824B2 (en) | 2011-05-31 |
WO2007093542A1 (en) | 2007-08-23 |
CA2640582A1 (en) | 2007-08-23 |
KR20080085233A (ko) | 2008-09-23 |
CN101384554B (zh) | 2012-08-08 |
EP1987003A1 (en) | 2008-11-05 |
CN101384554A (zh) | 2009-03-11 |
JP2009526809A (ja) | 2009-07-23 |
AR059512A1 (es) | 2008-04-09 |
IL193175A0 (en) | 2009-02-11 |
JP4975763B2 (ja) | 2012-07-11 |
KR101069106B1 (ko) | 2011-09-30 |
ZA200806809B (en) | 2009-10-28 |
BRPI0707949A2 (pt) | 2011-05-17 |
US20070197553A1 (en) | 2007-08-23 |
TWI360547B (en) | 2012-03-21 |
RU2427580C2 (ru) | 2011-08-27 |
TW200808765A (en) | 2008-02-16 |
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