NO20076325L - Dispersible bosertan tablet - Google Patents
Dispersible bosertan tabletInfo
- Publication number
- NO20076325L NO20076325L NO20076325A NO20076325A NO20076325L NO 20076325 L NO20076325 L NO 20076325L NO 20076325 A NO20076325 A NO 20076325A NO 20076325 A NO20076325 A NO 20076325A NO 20076325 L NO20076325 L NO 20076325L
- Authority
- NO
- Norway
- Prior art keywords
- dispersible
- bosertan
- tablet
- benzenesulfonamide
- pyrimidin
- Prior art date
Links
- -1 2-hydroxy-ethoxy Chemical group 0.000 abstract 2
- KHBQMWCZKVMBLN-UHFFFAOYSA-N Benzenesulfonamide Chemical compound NS(=O)(=O)C1=CC=CC=C1 KHBQMWCZKVMBLN-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000007919 dispersible tablet Substances 0.000 abstract 1
- 125000000246 pyrimidin-2-yl group Chemical group [H]C1=NC(*)=NC([H])=C1[H] 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Den foreliggende oppfinnelsen vedrører dispergerbare tabletter omfattende forbindelsen 4- tert-butyl-N-[6-(2-hydroksy-etoksy)-5-(2-metoksy-fenoksy)-2-(pyrimidin-2-yl)-pyrimidin- 4-yl]-benzensulfonamid.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP2005005367 | 2005-05-17 | ||
PCT/IB2006/051519 WO2006123285A2 (en) | 2005-05-17 | 2006-05-15 | Dispersible bosertan tablet |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20076325L true NO20076325L (no) | 2008-02-04 |
NO339781B1 NO339781B1 (no) | 2017-01-30 |
Family
ID=37431647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20076325A NO339781B1 (no) | 2005-05-17 | 2007-12-10 | Dispergerbar tablett |
Country Status (24)
Country | Link |
---|---|
US (3) | US7959945B2 (no) |
EP (1) | EP1883397B1 (no) |
JP (1) | JP4219399B2 (no) |
KR (2) | KR20080014002A (no) |
CN (1) | CN101175484B (no) |
AT (1) | ATE451914T1 (no) |
AU (1) | AU2006248593B2 (no) |
BR (1) | BRPI0610187B8 (no) |
CA (1) | CA2607098C (no) |
CY (1) | CY1110610T1 (no) |
DE (1) | DE602006011150D1 (no) |
DK (1) | DK1883397T3 (no) |
ES (1) | ES2336943T3 (no) |
HK (1) | HK1120212A1 (no) |
IL (1) | IL187383A (no) |
MX (1) | MX2007014454A (no) |
NO (1) | NO339781B1 (no) |
NZ (1) | NZ564167A (no) |
PL (1) | PL1883397T3 (no) |
PT (1) | PT1883397E (no) |
RU (2) | RU2404774C2 (no) |
SI (1) | SI1883397T1 (no) |
WO (1) | WO2006123285A2 (no) |
ZA (1) | ZA200710903B (no) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4219399B2 (ja) | 2005-05-17 | 2009-02-04 | アクテリオン ファーマシューティカルズ リミテッド | 分散性錠剤 |
WO2009004374A1 (en) | 2007-06-29 | 2009-01-08 | Generics [Uk] Limited | Process for introduction of hydroxyethoxy side chain in bosentan |
CA2712860C (en) | 2008-02-08 | 2014-11-18 | Abhay Gaitonde | Process for preparing bosentan |
CN102272108A (zh) | 2008-11-03 | 2011-12-07 | 基因里克斯(英国)有限公司 | 用于分析波生坦及相关物质的hplc方法以及这些物质作为参比标准和标记的用途 |
JP5850576B2 (ja) * | 2010-07-06 | 2016-02-03 | 富士化学工業株式会社 | ボセンタン固体分散体 |
CN102114005B (zh) * | 2010-12-06 | 2012-12-12 | 武汉武药科技有限公司 | 一种波生坦胶囊及其制备方法 |
WO2012139736A1 (en) | 2011-04-11 | 2012-10-18 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Pharmaceutical composition comprising bosentan |
ES2841809T3 (es) | 2011-06-03 | 2021-07-09 | Eisai R&D Man Co Ltd | Biomarcadores para pronosticar y evaluar el grado de respuesta de sujetos con cáncer de tiroides y de riñón a compuestos de lenvatinib |
JP2015503555A (ja) | 2012-05-11 | 2015-02-02 | ハナル・バイオファーマ・カンパニー・リミテッド | ボセンタン制御放出性経口製剤 |
KR101451327B1 (ko) * | 2013-01-08 | 2014-11-03 | 안국약품 주식회사 | 보센탄의 제어방출성 다층 정제 및 그 제조방법 |
RU2559424C1 (ru) * | 2014-06-18 | 2015-08-10 | Федеральное государственное бюджетное учреждение "Российский кардиологический научно-производственный комплекс" Министерства здравоохранения Российской Федерации (ФГБУ "РКНПК" Минздрава России) | Способ подбора лекарственной терапии больным с идиопатической легочной гипертензией |
ES2926687T3 (es) | 2014-08-28 | 2022-10-27 | Eisai R&D Man Co Ltd | Derivado de quinolina muy puro y método para su producción |
HUE064614T2 (hu) | 2015-02-25 | 2024-04-28 | Eisai R&D Man Co Ltd | Eljárás egy kinolin-származék keserû ízének elnyomására |
CN104840965B (zh) * | 2015-05-05 | 2018-05-08 | 重庆华邦制药有限公司 | 波生坦的制剂及其稳定剂 |
KR20160141045A (ko) | 2015-05-27 | 2016-12-08 | 한올바이오파마주식회사 | 보센탄을 함유한 약학적 조성물 |
AU2016279474B2 (en) | 2015-06-16 | 2021-09-09 | Eisai R&D Management Co., Ltd. | Anticancer agent |
CN108703956A (zh) * | 2018-08-21 | 2018-10-26 | 天津双硕医药科技有限公司 | 一种含有波生坦的固体药物组合物 |
CA3161960A1 (en) | 2019-12-16 | 2021-06-24 | Tenax Therapeutics, Inc. | Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (ph-hfpef) |
WO2023107066A2 (en) * | 2021-12-07 | 2023-06-15 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | Bosentan pharmaceutical compositions |
WO2023128902A1 (en) * | 2021-12-30 | 2023-07-06 | Pharmactive Ilac Sanayi Ve Ticaret A.S. | Pharmaceutical compositions comprising bosentan and relevant excipients |
CN114533738A (zh) * | 2022-02-19 | 2022-05-27 | 苏州海景医药科技有限公司 | 一种波生坦固体药物组合物及其制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2086544C1 (ru) * | 1991-06-13 | 1997-08-10 | Хоффманн-Ля Рош АГ | Бензолсульфонамидные производные пиримидина или их соли, фармацевтическая композиция для лечения заболеваний, связанных с активностью эндотелина |
ES2082723B1 (es) * | 1994-07-20 | 1996-10-01 | Lilly Sa | Formulacion farmaceutica de fluoxetina en forma dispersable. |
US6635648B2 (en) * | 2000-08-18 | 2003-10-21 | Queen's University At Kingston | Combination therapy using sympathetic nervous system antagonists and endothelin antagonists |
EP1509524B1 (en) * | 2002-05-31 | 2008-03-26 | Schering Corporation | Xanthine phosphodiesterase v inhibitor polymorphs |
KR100604034B1 (ko) | 2003-10-08 | 2006-07-24 | 주식회사유한양행 | 암로디핀 유리염기를 함유한 구강 속붕해정 및 그의 조성물 |
JP4219399B2 (ja) * | 2005-05-17 | 2009-02-04 | アクテリオン ファーマシューティカルズ リミテッド | 分散性錠剤 |
-
2006
- 2006-05-15 JP JP2008510716A patent/JP4219399B2/ja active Active
- 2006-05-15 ES ES06744942T patent/ES2336943T3/es active Active
- 2006-05-15 AT AT06744942T patent/ATE451914T1/de active
- 2006-05-15 MX MX2007014454A patent/MX2007014454A/es active IP Right Grant
- 2006-05-15 KR KR1020077028463A patent/KR20080014002A/ko active Application Filing
- 2006-05-15 PL PL06744942T patent/PL1883397T3/pl unknown
- 2006-05-15 CN CN2006800166119A patent/CN101175484B/zh active Active
- 2006-05-15 AU AU2006248593A patent/AU2006248593B2/en active Active
- 2006-05-15 RU RU2007146395/15A patent/RU2404774C2/ru active
- 2006-05-15 PT PT06744942T patent/PT1883397E/pt unknown
- 2006-05-15 EP EP06744942A patent/EP1883397B1/en active Active
- 2006-05-15 BR BRPI0610187A patent/BRPI0610187B8/pt active IP Right Grant
- 2006-05-15 CA CA2607098A patent/CA2607098C/en not_active Expired - Fee Related
- 2006-05-15 KR KR1020107014762A patent/KR20100093105A/ko not_active Application Discontinuation
- 2006-05-15 NZ NZ564167A patent/NZ564167A/en unknown
- 2006-05-15 WO PCT/IB2006/051519 patent/WO2006123285A2/en active Application Filing
- 2006-05-15 DK DK06744942.1T patent/DK1883397T3/da active
- 2006-05-15 US US11/914,652 patent/US7959945B2/en active Active
- 2006-05-15 SI SI200630581T patent/SI1883397T1/sl unknown
- 2006-05-15 DE DE602006011150T patent/DE602006011150D1/de active Active
-
2007
- 2007-11-15 IL IL187383A patent/IL187383A/en active IP Right Grant
- 2007-12-10 NO NO20076325A patent/NO339781B1/no unknown
- 2007-12-14 ZA ZA200710903A patent/ZA200710903B/xx unknown
-
2008
- 2008-11-04 HK HK08112061.1A patent/HK1120212A1/xx unknown
-
2010
- 2010-03-09 CY CY20101100220T patent/CY1110610T1/el unknown
- 2010-07-16 RU RU2010129460/15A patent/RU2010129460A/ru not_active Application Discontinuation
-
2011
- 2011-06-07 US US13/154,588 patent/US8309126B2/en active Active
-
2012
- 2012-09-27 US US13/628,780 patent/US20130023547A1/en not_active Abandoned
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