NO20076298L - Ekstruderingsprosess for fremstilling av sammensetninger som inneholder terapeutiske forbindelser som er lite sammenpressbare - Google Patents
Ekstruderingsprosess for fremstilling av sammensetninger som inneholder terapeutiske forbindelser som er lite sammenpressbareInfo
- Publication number
- NO20076298L NO20076298L NO20076298A NO20076298A NO20076298L NO 20076298 L NO20076298 L NO 20076298L NO 20076298 A NO20076298 A NO 20076298A NO 20076298 A NO20076298 A NO 20076298A NO 20076298 L NO20076298 L NO 20076298L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- therapeutic compounds
- compressible
- compositions containing
- extrusion process
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67958705P | 2005-05-10 | 2005-05-10 | |
US69315505P | 2005-06-23 | 2005-06-23 | |
PCT/US2006/017708 WO2006122021A1 (en) | 2005-05-10 | 2006-05-08 | Extrusion process for making compositions with poorly compressible therapeutic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20076298L true NO20076298L (no) | 2007-12-06 |
Family
ID=37022916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20076298A NO20076298L (no) | 2005-05-10 | 2007-12-06 | Ekstruderingsprosess for fremstilling av sammensetninger som inneholder terapeutiske forbindelser som er lite sammenpressbare |
Country Status (16)
Country | Link |
---|---|
US (2) | US20100152299A1 (pt) |
EP (1) | EP1881819A1 (pt) |
JP (1) | JP5400377B2 (pt) |
KR (2) | KR20080007357A (pt) |
CN (1) | CN102552162A (pt) |
AU (2) | AU2006244213B2 (pt) |
BR (1) | BRPI0608609A2 (pt) |
CA (1) | CA2607624A1 (pt) |
IL (1) | IL186456A0 (pt) |
MA (1) | MA29465B1 (pt) |
MX (1) | MX2007014041A (pt) |
NO (1) | NO20076298L (pt) |
NZ (2) | NZ562304A (pt) |
RU (1) | RU2405539C2 (pt) |
TN (1) | TNSN07415A1 (pt) |
WO (1) | WO2006122021A1 (pt) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
GB2447898B (en) * | 2007-03-24 | 2011-08-17 | Reckitt Benckiser Healthcare | A tablet having improved stability with at least two actives |
BRPI0906467C1 (pt) | 2008-01-25 | 2021-05-25 | Gruenenthal Gmbh | forma de dosagem farmacêutica com formato exterior modificado resistente à ruptura e com liberação controlada |
AU2009243139A1 (en) * | 2008-04-30 | 2009-11-05 | Novartis Ag | Continuous process for making pharmaceutical compositions |
ES2393949T3 (es) * | 2008-07-03 | 2013-01-02 | Novartis Ag | Proceso de granulación en estado fundido |
EP2456427B1 (en) | 2009-07-22 | 2015-03-04 | Grünenthal GmbH | Hot-melt extruded controlled release dosage form |
AU2010275754B2 (en) | 2009-07-22 | 2014-05-15 | Grünenthal GmbH | Tamper-resistant dosage form for oxidation-sensitive opioids |
MX2013002293A (es) | 2010-09-02 | 2013-05-09 | Gruenenthal Gmbh | Forma de dosificacion resistente a alteracion que comprende un polimero anionico. |
WO2012028319A1 (en) | 2010-09-02 | 2012-03-08 | Grünenthal GmbH | Tamper resistant dosage form comprising inorganic salt |
BR112014002022A2 (pt) | 2011-07-29 | 2017-02-21 | Gruenenthal Gmbh | comprimido resistente à violação proporcionando liberação de fármaco imediata |
LT2736497T (lt) | 2011-07-29 | 2017-11-10 | Grünenthal GmbH | Sugadinimui atspari tabletė, pasižyminti greitu vaisto atpalaidavimu |
US20130225697A1 (en) | 2012-02-28 | 2013-08-29 | Grunenthal Gmbh | Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer |
AU2013248351B2 (en) | 2012-04-18 | 2018-04-26 | Grunenthal Gmbh | Tamper resistant and dose-dumping resistant pharmaceutical dosage form |
US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
GB201218012D0 (en) | 2012-10-08 | 2012-11-21 | Jagotec Ag | Dosage forms |
JP6466417B2 (ja) | 2013-05-29 | 2019-02-06 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 二峰性放出プロファイルを有する改変防止(tamper−resistant)剤形 |
CA2907950A1 (en) | 2013-05-29 | 2014-12-04 | Grunenthal Gmbh | Tamper-resistant dosage form containing one or more particles |
EA032465B1 (ru) | 2013-07-12 | 2019-05-31 | Грюненталь Гмбх | Защищенная от применения не по назначению пероральная фармацевтическая лекарственная форма, содержащая этиленвинилацетатный полимер, и способ ее изготовления |
WO2015023675A2 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
AU2014356581C1 (en) | 2013-11-26 | 2020-05-28 | Grunenthal Gmbh | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
CN106572980A (zh) | 2014-05-12 | 2017-04-19 | 格吕伦塔尔有限公司 | 包含他喷他多的防篡改即释胶囊制剂 |
CN106456550A (zh) | 2014-05-26 | 2017-02-22 | 格吕伦塔尔有限公司 | 避免乙醇剂量倾泻的多颗粒 |
US9707184B2 (en) | 2014-07-17 | 2017-07-18 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
CA2964628A1 (en) | 2014-10-20 | 2016-04-28 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
WO2016170094A1 (en) | 2015-04-24 | 2016-10-27 | Grünenthal GmbH | Tamper-resistant fixed dose combination providing fast release of two drugs from particles |
CA2983640A1 (en) | 2015-04-24 | 2016-10-27 | Grunenthal Gmbh | Tamper-resistant fixed dose combination providing fast release of two drugs from different particles |
AU2016251854A1 (en) | 2015-04-24 | 2017-10-19 | Grunenthal Gmbh | Tamper-resistant dosage form with immediate release and resistance against solvent extraction |
JP2018513864A (ja) | 2015-04-24 | 2018-05-31 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 粒子及びマトリックスから2種の薬物の急速放出をもたらすタンパレジスタントな固定用量組合せ |
JP2018526414A (ja) | 2015-09-10 | 2018-09-13 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護 |
DE102018010063A1 (de) | 2018-03-16 | 2019-09-19 | Ludwig-Maximilians-Universität München | Herstellung vesikulärer Phospholipid-Gele durch Schnecken-Extrusion |
CN108888599B (zh) * | 2018-07-26 | 2021-06-08 | 国药集团致君(深圳)制药有限公司 | 双氯芬酸钠缓释组合物及其制备方法 |
WO2023088962A1 (en) * | 2021-11-16 | 2023-05-25 | Dsm Ip Assets B.V. | Granule comprising encapsulated active ingredients |
WO2023088886A1 (en) * | 2021-11-16 | 2023-05-25 | Dsm Ip Assets B.V. | High potency granules obtainable by continuous melt granulation |
WO2023145871A1 (ja) * | 2022-01-31 | 2023-08-03 | 住友精化株式会社 | 製剤用組成物の製造方法及び製剤の製造方法 |
WO2023145869A1 (ja) * | 2022-01-31 | 2023-08-03 | 住友精化株式会社 | 製剤用組成物の製造方法及び製剤の製造方法 |
TW202412735A (zh) * | 2022-08-31 | 2024-04-01 | 義大利商沙克米機械合作伊莫拉公司 | 製造固體藥劑的方法及裝置 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
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FR2571046B1 (fr) * | 1984-10-03 | 1987-10-16 | Roquette Freres | Procede de preparation de mannitol granulaire directement compressible |
US5965161A (en) * | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
DE19504832A1 (de) * | 1995-02-14 | 1996-08-22 | Basf Ag | Feste Wirkstoff-Zubereitungen |
DE19504831A1 (de) * | 1995-02-14 | 1996-09-05 | Basf Ag | Feste Wirkstoffzubereitungen enthaltend Hydroxypropylcellulose |
DE19509806A1 (de) * | 1995-03-21 | 1996-09-26 | Basf Ag | Lagerstabile Arzneiformen |
DE19721467A1 (de) * | 1997-05-22 | 1998-11-26 | Basf Ag | Verfahren zur Herstellung kleinteiliger Zubereitungen biologisch aktiver Stoffe |
HN1998000115A (es) * | 1997-08-21 | 1999-06-02 | Warner Lambert Co | Formas de dosificación farmacéuticas sólidas |
DE19934610A1 (de) * | 1999-07-23 | 2001-01-25 | Bayer Ag | Schnellfreisetzende Extrudate und Verfahren zu ihrer Herstellung sowie daraus erhältliche Zubereitungen |
WO2002028181A1 (en) * | 2000-10-02 | 2002-04-11 | Usv Limited | Sustained release pharmaceutical compositions containing metformin and method of its production |
US20030021841A1 (en) * | 2001-07-02 | 2003-01-30 | Matharu Amol Singh | Pharmaceutical composition |
IN192180B (pt) * | 2001-09-28 | 2004-03-06 | Ranbaxy Lab | |
KR20040044992A (ko) * | 2001-09-28 | 2004-05-31 | 썬 파마슈티컬 인더스트리스 리미티드 | 당뇨병 치료용 투여형태 |
FR2858556B1 (fr) * | 2003-08-06 | 2006-03-10 | Galenix Innovations | Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation |
DE102005005446A1 (de) * | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
JP2007526309A (ja) * | 2004-03-02 | 2007-09-13 | アベール ファーマシューティカルズ インコーポレイテッド | 生物活性剤の混合製剤またはキット |
JOP20180109A1 (ar) * | 2005-09-29 | 2019-01-30 | Novartis Ag | تركيبة جديدة |
JP5284101B2 (ja) * | 2005-11-09 | 2013-09-11 | ノバルティス アーゲー | 一時可塑剤を用いる医薬組成物の製造法 |
-
2006
- 2006-05-08 EP EP06759308A patent/EP1881819A1/en not_active Withdrawn
- 2006-05-08 KR KR1020077026095A patent/KR20080007357A/ko not_active Application Discontinuation
- 2006-05-08 US US11/909,509 patent/US20100152299A1/en not_active Abandoned
- 2006-05-08 BR BRPI0608609-8A patent/BRPI0608609A2/pt not_active IP Right Cessation
- 2006-05-08 CN CN2011103445944A patent/CN102552162A/zh active Pending
- 2006-05-08 WO PCT/US2006/017708 patent/WO2006122021A1/en active Application Filing
- 2006-05-08 MX MX2007014041A patent/MX2007014041A/es active IP Right Grant
- 2006-05-08 NZ NZ562304A patent/NZ562304A/en not_active IP Right Cessation
- 2006-05-08 AU AU2006244213A patent/AU2006244213B2/en not_active Ceased
- 2006-05-08 CA CA002607624A patent/CA2607624A1/en not_active Abandoned
- 2006-05-08 JP JP2008511233A patent/JP5400377B2/ja not_active Expired - Fee Related
- 2006-05-08 NZ NZ585116A patent/NZ585116A/en not_active IP Right Cessation
- 2006-05-08 KR KR1020137031633A patent/KR20130135403A/ko not_active Application Discontinuation
- 2006-05-08 RU RU2007145522/15A patent/RU2405539C2/ru not_active IP Right Cessation
-
2007
- 2007-10-07 IL IL186456A patent/IL186456A0/en unknown
- 2007-11-09 TN TNP2007000415A patent/TNSN07415A1/en unknown
- 2007-11-20 MA MA30393A patent/MA29465B1/fr unknown
- 2007-12-06 NO NO20076298A patent/NO20076298L/no not_active Application Discontinuation
-
2010
- 2010-08-12 AU AU2010212296A patent/AU2010212296B2/en not_active Ceased
-
2011
- 2011-11-30 US US13/307,864 patent/US20120077879A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
NZ562304A (en) | 2010-06-25 |
RU2405539C2 (ru) | 2010-12-10 |
TNSN07415A1 (en) | 2009-03-17 |
JP2008540540A (ja) | 2008-11-20 |
AU2006244213A1 (en) | 2006-11-16 |
RU2007145522A (ru) | 2009-06-20 |
CA2607624A1 (en) | 2006-11-16 |
US20100152299A1 (en) | 2010-06-17 |
EP1881819A1 (en) | 2008-01-30 |
WO2006122021A1 (en) | 2006-11-16 |
KR20080007357A (ko) | 2008-01-18 |
CN102552162A (zh) | 2012-07-11 |
AU2006244213B2 (en) | 2010-05-13 |
BRPI0608609A2 (pt) | 2010-01-19 |
AU2010212296B2 (en) | 2011-06-16 |
JP5400377B2 (ja) | 2014-01-29 |
MA29465B1 (fr) | 2008-05-02 |
IL186456A0 (en) | 2008-01-20 |
KR20130135403A (ko) | 2013-12-10 |
NZ585116A (en) | 2011-12-22 |
MX2007014041A (es) | 2008-02-11 |
US20120077879A1 (en) | 2012-03-29 |
AU2010212296A1 (en) | 2010-09-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |