NO20076083L - Mukoadhesive xyloglukaninneholdende formuleringer som er anvendelige i medisinske anordninger og i farmasoytiske formuleringer - Google Patents
Mukoadhesive xyloglukaninneholdende formuleringer som er anvendelige i medisinske anordninger og i farmasoytiske formuleringerInfo
- Publication number
- NO20076083L NO20076083L NO20076083A NO20076083A NO20076083L NO 20076083 L NO20076083 L NO 20076083L NO 20076083 A NO20076083 A NO 20076083A NO 20076083 A NO20076083 A NO 20076083A NO 20076083 L NO20076083 L NO 20076083L
- Authority
- NO
- Norway
- Prior art keywords
- formulations
- mucoadhesive
- medical devices
- xyloglucan
- pharmaceutical
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000003232 mucoadhesive effect Effects 0.000 title abstract 3
- 229920002000 Xyloglucan Polymers 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- 210000004400 mucous membrane Anatomy 0.000 abstract 3
- 239000004902 Softening Agent Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 230000003020 moisturizing effect Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Otolaryngology (AREA)
- Communicable Diseases (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Virology (AREA)
Abstract
Målet for oppfinnelsen er frigjøringsformuleringer med mukoadhesive og kontrollerte egenskaper bestående av vandige oppløsninger inneholdende 0,05 til 5 vekt% av en naturlig renset polymer med xyloglukanstruktur og 10 til 70 vekt% glyserol. Disse formuleringer er egnet til applikasjon på humane mukøse membraner så som nese, orale og vaginale mukøse membraner, som fuktende og mykgjørende midler eller som farmasøytisk frigjøringssystem. Ytterligere mål for oppfinnelsen er farmasøytiske formuleringer og medisinske anordninger som er egnet for applikasjon på humane mukøse membraner, inneholdende de mukoadhesive og kontrollerte frigjøringsformuleringer sammen med aktive bestanddeler og eksipienter. ?? ?? ?? ??
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000388A ITBO20050388A1 (it) | 2005-06-06 | 2005-06-06 | Formulazione mucoadesive utili in dispositivi medici in preparazioni farmaceutiche |
| PCT/EP2006/005240 WO2006131262A1 (en) | 2005-06-06 | 2006-06-01 | Mucoadhesive xyloglucan-containing formulations useful in medical devices and in pharmaceutical formulations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20076083L true NO20076083L (no) | 2007-11-26 |
| NO338991B1 NO338991B1 (no) | 2016-11-07 |
Family
ID=36954507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20076083A NO338991B1 (no) | 2005-06-06 | 2007-11-26 | Mukoadhesive xyloglukaninneholdende formuleringer som er anvendelige i medisinske anordninger og i farmasøytiske formuleringer |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US20090081133A1 (no) |
| EP (1) | EP1898876B1 (no) |
| JP (1) | JP5118633B2 (no) |
| KR (1) | KR101337578B1 (no) |
| CN (2) | CN102079794B (no) |
| AT (1) | ATE418324T1 (no) |
| BR (1) | BRPI0611400B8 (no) |
| CA (1) | CA2604768C (no) |
| CY (1) | CY1108875T1 (no) |
| DE (1) | DE602006004451D1 (no) |
| DK (1) | DK1898876T3 (no) |
| ES (1) | ES2318756T3 (no) |
| IL (1) | IL186655A (no) |
| IT (1) | ITBO20050388A1 (no) |
| MX (1) | MX2007015074A (no) |
| NO (1) | NO338991B1 (no) |
| PL (1) | PL1898876T3 (no) |
| PT (1) | PT1898876E (no) |
| RU (1) | RU2403012C2 (no) |
| SI (1) | SI1898876T1 (no) |
| UA (1) | UA90507C2 (no) |
| WO (1) | WO2006131262A1 (no) |
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| PT1698630E (pt) | 2005-03-03 | 2014-09-15 | Alfa Wassermann Spa | Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais |
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| CN102026663A (zh) * | 2008-04-11 | 2011-04-20 | 赛姆生物系统遗传公司 | 油质体中活性剂的控制释放 |
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| IT1397132B1 (it) | 2009-12-01 | 2013-01-04 | Alfa Wassermann Spa | Composizioni comprendenti antiinfiammatori non steroidei. |
| JP2013526594A (ja) | 2010-05-24 | 2013-06-24 | インデナ エッセ ピ ア | 微生物感染の治療に使用するためのタマリンド種子多糖 |
| CA2800383C (en) | 2010-05-24 | 2019-06-25 | Indena S.P.A. | Tamarind seed polysaccharide for use in the treatment of inflammatory diseases |
| CN103189046B (zh) | 2010-09-09 | 2016-09-07 | 玫琳凯有限公司 | 包含植物提取物的局部护肤制剂 |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| ES2885523T3 (es) | 2011-11-23 | 2021-12-14 | Therapeuticsmd Inc | Formulaciones y terapias de reposición hormonal de combinación naturales |
| US9091622B2 (en) | 2011-12-20 | 2015-07-28 | Exxonmobil Upstream Research Company | Capillary-based calibration standards for measurement of permeability |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| CA2870170C (en) | 2012-09-12 | 2018-06-12 | Boston Scientific Scimed, Inc. | Adhesive stent coating for anti-migration |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| ITMI20130960A1 (it) * | 2013-06-11 | 2014-12-12 | Novintethical Pharma Sagl | Composizioni a base di xiloglucano per il trattamento di disturbi gastrointestinali |
| US20150094266A1 (en) * | 2013-06-11 | 2015-04-02 | Novintethical Pharma, SA | Xyloglucan and protein compositions for the treatment of intestinal disorders |
| ITMI20132103A1 (it) * | 2013-12-16 | 2015-06-17 | Novintethical Pharma Sagl | Composizioni topiche nasali contenenti xiloglucani per uso come decongestionanti |
| CA2945631C (en) | 2014-04-15 | 2023-04-11 | Novintethical Pharma Sa | Compositions based on xyloglucan and proteins for the treatment of intestinal disorders |
| MX2016014281A (es) | 2014-05-22 | 2017-02-22 | Therapeuticsmd Inc | Formulaciones y terapias de reemplazo de combinación de hormonas naturales. |
| MX2016013693A (es) | 2014-07-29 | 2017-10-31 | Therapeuticsmd Inc | Crema transdermica. |
| US11623008B2 (en) | 2014-08-20 | 2023-04-11 | Professional Compounding Centers Of America | Excipient compositions for mucoadhesive pharmaceutical compositions including a synergistic combination of amylopectin, pullulan, hyaluronic acid, and xyloglucan |
| EP3103438B1 (en) | 2015-06-11 | 2018-11-14 | Novintethical Pharma SA | Topical nasal compositions containing xyloglucans for use as decongestans |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| AU2017239645A1 (en) | 2016-04-01 | 2018-10-18 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US10780146B2 (en) | 2016-05-31 | 2020-09-22 | Devintec Sagl | Compositions for the treatment of intestinal disorders |
| WO2018007288A1 (en) * | 2016-07-08 | 2018-01-11 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | Pharmaceutical composition comprising benzydamine |
| IT201700108526A1 (it) | 2017-09-28 | 2019-03-28 | Alfasigma Spa | Composizioni orali per il trattamento del refluso gastroesofageo. |
| PT3986378T (pt) | 2019-06-21 | 2026-02-18 | Alfasigma Spa | Composições farmacêuticas sob a forma de gel que contêm xiloglucano e álcoois para a libertação controlada de ingredientes ativos |
| IT202100010802A1 (it) | 2021-05-03 | 2022-11-03 | Alfasigma Spa | Formulazione solida mucoadesiva comprendente probiotici per uso nella prevenzione e nel trattamento di disbiosi orale. |
| JP2023084941A (ja) * | 2021-12-08 | 2023-06-20 | Mp五協フード&ケミカル株式会社 | 噴霧用組成物 |
| CN114306237A (zh) * | 2022-01-06 | 2022-04-12 | 江苏爱朋医疗科技股份有限公司 | 一种鼻腔护理喷雾剂及其制备方法和应用 |
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2005
- 2005-06-06 IT IT000388A patent/ITBO20050388A1/it unknown
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2006
- 2006-01-06 UA UAA200711344A patent/UA90507C2/uk unknown
- 2006-06-01 ES ES06754047T patent/ES2318756T3/es active Active
- 2006-06-01 RU RU2007143998/15A patent/RU2403012C2/ru active
- 2006-06-01 AT AT06754047T patent/ATE418324T1/de active
- 2006-06-01 CN CN2010105570198A patent/CN102079794B/zh active Active
- 2006-06-01 KR KR1020077028142A patent/KR101337578B1/ko not_active Expired - Fee Related
- 2006-06-01 CA CA2604768A patent/CA2604768C/en active Active
- 2006-06-01 SI SI200630188T patent/SI1898876T1/sl unknown
- 2006-06-01 JP JP2008514019A patent/JP5118633B2/ja active Active
- 2006-06-01 PL PL06754047T patent/PL1898876T3/pl unknown
- 2006-06-01 BR BRPI0611400A patent/BRPI0611400B8/pt not_active IP Right Cessation
- 2006-06-01 MX MX2007015074A patent/MX2007015074A/es active IP Right Grant
- 2006-06-01 DK DK06754047T patent/DK1898876T3/da active
- 2006-06-01 EP EP06754047A patent/EP1898876B1/en active Active
- 2006-06-01 US US11/921,286 patent/US20090081133A1/en not_active Abandoned
- 2006-06-01 CN CN2006800176445A patent/CN101180036B/zh active Active
- 2006-06-01 WO PCT/EP2006/005240 patent/WO2006131262A1/en not_active Ceased
- 2006-06-01 DE DE602006004451T patent/DE602006004451D1/de active Active
- 2006-06-01 PT PT06754047T patent/PT1898876E/pt unknown
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2007
- 2007-10-15 IL IL186655A patent/IL186655A/en active IP Right Grant
- 2007-11-26 NO NO20076083A patent/NO338991B1/no not_active IP Right Cessation
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2009
- 2009-03-12 CY CY20091100281T patent/CY1108875T1/el unknown
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2011
- 2011-10-19 US US13/277,130 patent/US20120088726A1/en not_active Abandoned
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2013
- 2013-01-23 US US13/747,889 patent/US20130183325A1/en not_active Abandoned
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