BR9901782A - Forma para dosagem de nefazodona. - Google Patents

Forma para dosagem de nefazodona.

Info

Publication number
BR9901782A
BR9901782A BR9901782-2A BR9901782A BR9901782A BR 9901782 A BR9901782 A BR 9901782A BR 9901782 A BR9901782 A BR 9901782A BR 9901782 A BR9901782 A BR 9901782A
Authority
BR
Brazil
Prior art keywords
nefazodone
release
compositions
dosage form
dosage forms
Prior art date
Application number
BR9901782-2A
Other languages
English (en)
Inventor
Andrew B Dennis
Peter Timmins
Alison C Hodsdon
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of BR9901782A publication Critical patent/BR9901782A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

"FORMA PARA DOSAGEM DE NEFAZODONA" Composições de nefazodona de liberação prolongada contendo cloreto de nefazodona, polímeros de gelificação iónicos e não iónicos, um agente hidrófilo insolúvel e excipientes opcionais farmaceuticamente aceitáveis demonstrando liberação de nefazodona modulada por pH. Estas composições são formuladas nas formas de dosagem unitária para administração oral aperfeiçoada. Os aperfeiçoamentos compreendem um perfil de liberação de droga prolongado, provendo níveis comparativos de nefazodona com relação às formas de dosagem de liberação imediata e, adicionalmente, demonstrado a falta de um efeito em alimentação.
BR9901782-2A 1998-06-05 1999-06-04 Forma para dosagem de nefazodona. BR9901782A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8821198P 1998-06-05 1998-06-05

Publications (1)

Publication Number Publication Date
BR9901782A true BR9901782A (pt) 2000-05-09

Family

ID=22210038

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9901782-2A BR9901782A (pt) 1998-06-05 1999-06-04 Forma para dosagem de nefazodona.

Country Status (20)

Country Link
US (1) US6143325A (pt)
EP (1) EP0966966A3 (pt)
JP (1) JP2000007567A (pt)
KR (1) KR20000005930A (pt)
CN (1) CN1238181A (pt)
AR (1) AR018862A1 (pt)
AU (1) AU3319999A (pt)
BR (1) BR9901782A (pt)
CA (1) CA2273546A1 (pt)
CO (1) CO5060477A1 (pt)
HU (1) HUP9901830A2 (pt)
ID (1) ID23458A (pt)
IL (1) IL130022A0 (pt)
NO (1) NO992692L (pt)
NZ (1) NZ336001A (pt)
PE (1) PE20000544A1 (pt)
PL (1) PL333524A1 (pt)
SG (1) SG77244A1 (pt)
UY (1) UY25544A1 (pt)
ZA (1) ZA993345B (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143325A (en) * 1998-06-05 2000-11-07 Bristol-Myers Squibb Company Nefazodone dosage form
EP1428535A1 (en) * 1998-11-02 2004-06-16 ALZA Corporation Controlled delivery of antidepressants
US6706282B1 (en) 1998-11-02 2004-03-16 Evangeline Cruz Controlled delivery of phenoxyethyl-substituted 1,2,4-triazolones
ATE323493T1 (de) * 1998-11-02 2006-05-15 Alza Corp Gesteuerte freisetzung von antidepressiva
WO2002069951A2 (en) * 2001-03-02 2002-09-12 Sepracor Inc. Composition containing a nefazonoid such as nefazodone and a serotonin-inhibitor such as fluoxetine
US8329216B2 (en) 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
CN1268338C (zh) 2001-07-06 2006-08-09 恩德制药公司 用作止痛剂的6-羟基羟吗啡酮的口服给药
EP1404332A1 (en) 2001-07-06 2004-04-07 Penwest Pharmaceuticals Company Methods of making sustained release formulations of oxymorphone related applications
US6455557B1 (en) 2001-11-28 2002-09-24 Elan Pharmaceuticals, Inc. Method of reducing somnolence in patients treated with tizanidine
US20040220240A1 (en) * 2001-11-28 2004-11-04 Pellegrini Cara A. Method of increasing the extent of absorption of tizanidine
US7714006B1 (en) 2001-12-03 2010-05-11 King Pharmaceuticals Research & Development, Inc. Methods of modifying the bioavailability of metaxalone
US6407128B1 (en) 2001-12-03 2002-06-18 Elan Pharmaceuticals, Inc. Method for increasing the bioavailability of metaxalone
AU2003232805A1 (en) * 2002-05-24 2003-12-12 Carl-Fr. Coester Pharmaceutical active substance combination and the use thereof
TWI319713B (en) 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
US8487002B2 (en) 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
GB0306604D0 (en) * 2003-03-21 2003-04-30 Curidium Ltd Second medical use
PT1575565E (pt) * 2003-08-08 2010-03-03 Biovail Lab Int Srl Comprimido de libertação modificada de cloridrato de bupropiona
EP1732610A2 (en) 2004-03-26 2006-12-20 Baylor University Targeted serotonin reuptake inhibitors
JP5269595B2 (ja) 2005-09-09 2013-08-21 アンジェリーニ ラボファーム リミテッド ライアビリティ カンパニー 1日1回投与用トラゾドン組成物
US20080287508A1 (en) * 2007-05-18 2008-11-20 Intermune, Inc. Altering pharmacokinetics of pirfenidone therapy
US20100159001A1 (en) * 2008-12-19 2010-06-24 Cardinal John R Extended-Release Pharmaceutical Formulations
US20100160363A1 (en) * 2008-12-19 2010-06-24 Aaipharma Services Corp. Extended-release pharmaceutical formulations
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors
JP2011140510A (ja) * 2011-03-17 2011-07-21 Biovail Lab Inc 塩酸ブプロピオンの放出調節錠剤
CN113842362A (zh) 2012-11-14 2021-12-28 格雷斯公司 含有生物活性材料与无序无机氧化物的组合物
JP6184903B2 (ja) * 2014-06-04 2017-08-23 ヴァレアント インターナショナル バミューダValeant International Bermuda 塩酸ブプロピオン放出調節錠剤
JP6078514B2 (ja) * 2014-10-30 2017-02-08 コリア ユナイテッド ファーム,インク 溶出率向上と副作用発現が最小化されたシルロスタゾール徐放錠

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792452A (en) * 1987-07-28 1988-12-20 E. R. Squibb & Sons, Inc. Controlled release formulation
US4983398A (en) * 1987-12-21 1991-01-08 Forest Laboratories, Inc. Sustained release drug dosage forms containing hydroxypropylmethylcellulose and alkali metal carboxylates
US5431922A (en) * 1991-03-05 1995-07-11 Bristol-Myers Squibb Company Method for administration of buspirone
US5169638A (en) * 1991-10-23 1992-12-08 E. R. Squibb & Sons, Inc. Buoyant controlled release powder formulation
US5536507A (en) * 1994-06-24 1996-07-16 Bristol-Myers Squibb Company Colonic drug delivery system
WO1997011681A1 (en) * 1995-09-29 1997-04-03 Lam Pharmaceuticals Inc. Sustained release delivery system and long acting narcotic analgesics and antagonists
AU3290397A (en) * 1996-06-10 1998-01-07 Depomed, Inc. Gastric-retentive oral controlled drug delivery system with enhanced retention properties
US6143325A (en) * 1998-06-05 2000-11-07 Bristol-Myers Squibb Company Nefazodone dosage form

Also Published As

Publication number Publication date
AU3319999A (en) 1999-12-16
EP0966966A2 (en) 1999-12-29
IL130022A0 (en) 2000-02-29
HU9901830D0 (en) 1999-07-28
CA2273546A1 (en) 1999-10-10
PL333524A1 (en) 1999-12-06
NO992692L (no) 1999-12-06
PE20000544A1 (es) 2000-06-29
HUP9901830A2 (hu) 2001-06-28
NZ336001A (en) 2000-09-29
CN1238181A (zh) 1999-12-15
US6143325A (en) 2000-11-07
UY25544A1 (es) 2001-08-27
KR20000005930A (ko) 2000-01-25
SG77244A1 (en) 2000-12-19
JP2000007567A (ja) 2000-01-11
CO5060477A1 (es) 2001-07-30
EP0966966A3 (en) 2000-02-09
ZA993345B (en) 2000-08-22
ID23458A (id) 2000-04-27
AR018862A1 (es) 2001-12-12
NO992692D0 (no) 1999-06-03

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1910 DE 14/08/2007.