BR9901782A - Forma para dosagem de nefazodona. - Google Patents
Forma para dosagem de nefazodona.Info
- Publication number
- BR9901782A BR9901782A BR9901782-2A BR9901782A BR9901782A BR 9901782 A BR9901782 A BR 9901782A BR 9901782 A BR9901782 A BR 9901782A BR 9901782 A BR9901782 A BR 9901782A
- Authority
- BR
- Brazil
- Prior art keywords
- nefazodone
- release
- compositions
- dosage form
- dosage forms
- Prior art date
Links
- VRBKIVRKKCLPHA-UHFFFAOYSA-N nefazodone Chemical compound O=C1N(CCOC=2C=CC=CC=2)C(CC)=NN1CCCN(CC1)CCN1C1=CC=CC(Cl)=C1 VRBKIVRKKCLPHA-UHFFFAOYSA-N 0.000 title abstract 5
- 229960001800 nefazodone Drugs 0.000 title abstract 5
- 239000002552 dosage form Substances 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000013265 extended release Methods 0.000 abstract 1
- 238000001879 gelation Methods 0.000 abstract 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
"FORMA PARA DOSAGEM DE NEFAZODONA" Composições de nefazodona de liberação prolongada contendo cloreto de nefazodona, polímeros de gelificação iónicos e não iónicos, um agente hidrófilo insolúvel e excipientes opcionais farmaceuticamente aceitáveis demonstrando liberação de nefazodona modulada por pH. Estas composições são formuladas nas formas de dosagem unitária para administração oral aperfeiçoada. Os aperfeiçoamentos compreendem um perfil de liberação de droga prolongado, provendo níveis comparativos de nefazodona com relação às formas de dosagem de liberação imediata e, adicionalmente, demonstrado a falta de um efeito em alimentação.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8821198P | 1998-06-05 | 1998-06-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9901782A true BR9901782A (pt) | 2000-05-09 |
Family
ID=22210038
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9901782-2A BR9901782A (pt) | 1998-06-05 | 1999-06-04 | Forma para dosagem de nefazodona. |
Country Status (20)
Country | Link |
---|---|
US (1) | US6143325A (pt) |
EP (1) | EP0966966A3 (pt) |
JP (1) | JP2000007567A (pt) |
KR (1) | KR20000005930A (pt) |
CN (1) | CN1238181A (pt) |
AR (1) | AR018862A1 (pt) |
AU (1) | AU3319999A (pt) |
BR (1) | BR9901782A (pt) |
CA (1) | CA2273546A1 (pt) |
CO (1) | CO5060477A1 (pt) |
HU (1) | HUP9901830A2 (pt) |
ID (1) | ID23458A (pt) |
IL (1) | IL130022A0 (pt) |
NO (1) | NO992692L (pt) |
NZ (1) | NZ336001A (pt) |
PE (1) | PE20000544A1 (pt) |
PL (1) | PL333524A1 (pt) |
SG (1) | SG77244A1 (pt) |
UY (1) | UY25544A1 (pt) |
ZA (1) | ZA993345B (pt) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6143325A (en) * | 1998-06-05 | 2000-11-07 | Bristol-Myers Squibb Company | Nefazodone dosage form |
EP1428535A1 (en) * | 1998-11-02 | 2004-06-16 | ALZA Corporation | Controlled delivery of antidepressants |
US6706282B1 (en) | 1998-11-02 | 2004-03-16 | Evangeline Cruz | Controlled delivery of phenoxyethyl-substituted 1,2,4-triazolones |
ATE323493T1 (de) * | 1998-11-02 | 2006-05-15 | Alza Corp | Gesteuerte freisetzung von antidepressiva |
WO2002069951A2 (en) * | 2001-03-02 | 2002-09-12 | Sepracor Inc. | Composition containing a nefazonoid such as nefazodone and a serotonin-inhibitor such as fluoxetine |
US8329216B2 (en) | 2001-07-06 | 2012-12-11 | Endo Pharmaceuticals Inc. | Oxymorphone controlled release formulations |
CN1268338C (zh) | 2001-07-06 | 2006-08-09 | 恩德制药公司 | 用作止痛剂的6-羟基羟吗啡酮的口服给药 |
EP1404332A1 (en) | 2001-07-06 | 2004-04-07 | Penwest Pharmaceuticals Company | Methods of making sustained release formulations of oxymorphone related applications |
US6455557B1 (en) | 2001-11-28 | 2002-09-24 | Elan Pharmaceuticals, Inc. | Method of reducing somnolence in patients treated with tizanidine |
US20040220240A1 (en) * | 2001-11-28 | 2004-11-04 | Pellegrini Cara A. | Method of increasing the extent of absorption of tizanidine |
US7714006B1 (en) | 2001-12-03 | 2010-05-11 | King Pharmaceuticals Research & Development, Inc. | Methods of modifying the bioavailability of metaxalone |
US6407128B1 (en) | 2001-12-03 | 2002-06-18 | Elan Pharmaceuticals, Inc. | Method for increasing the bioavailability of metaxalone |
AU2003232805A1 (en) * | 2002-05-24 | 2003-12-12 | Carl-Fr. Coester | Pharmaceutical active substance combination and the use thereof |
TWI319713B (en) | 2002-10-25 | 2010-01-21 | Sustained-release tramadol formulations with 24-hour efficacy | |
US8487002B2 (en) | 2002-10-25 | 2013-07-16 | Paladin Labs Inc. | Controlled-release compositions |
GB0306604D0 (en) * | 2003-03-21 | 2003-04-30 | Curidium Ltd | Second medical use |
PT1575565E (pt) * | 2003-08-08 | 2010-03-03 | Biovail Lab Int Srl | Comprimido de libertação modificada de cloridrato de bupropiona |
EP1732610A2 (en) | 2004-03-26 | 2006-12-20 | Baylor University | Targeted serotonin reuptake inhibitors |
JP5269595B2 (ja) | 2005-09-09 | 2013-08-21 | アンジェリーニ ラボファーム リミテッド ライアビリティ カンパニー | 1日1回投与用トラゾドン組成物 |
US20080287508A1 (en) * | 2007-05-18 | 2008-11-20 | Intermune, Inc. | Altering pharmacokinetics of pirfenidone therapy |
US20100159001A1 (en) * | 2008-12-19 | 2010-06-24 | Cardinal John R | Extended-Release Pharmaceutical Formulations |
US20100160363A1 (en) * | 2008-12-19 | 2010-06-24 | Aaipharma Services Corp. | Extended-release pharmaceutical formulations |
WO2012072665A1 (en) | 2010-11-30 | 2012-06-07 | Pharmaneuroboost N.V. | Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors |
JP2011140510A (ja) * | 2011-03-17 | 2011-07-21 | Biovail Lab Inc | 塩酸ブプロピオンの放出調節錠剤 |
CN113842362A (zh) | 2012-11-14 | 2021-12-28 | 格雷斯公司 | 含有生物活性材料与无序无机氧化物的组合物 |
JP6184903B2 (ja) * | 2014-06-04 | 2017-08-23 | ヴァレアント インターナショナル バミューダValeant International Bermuda | 塩酸ブプロピオン放出調節錠剤 |
JP6078514B2 (ja) * | 2014-10-30 | 2017-02-08 | コリア ユナイテッド ファーム,インク | 溶出率向上と副作用発現が最小化されたシルロスタゾール徐放錠 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4792452A (en) * | 1987-07-28 | 1988-12-20 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
US4983398A (en) * | 1987-12-21 | 1991-01-08 | Forest Laboratories, Inc. | Sustained release drug dosage forms containing hydroxypropylmethylcellulose and alkali metal carboxylates |
US5431922A (en) * | 1991-03-05 | 1995-07-11 | Bristol-Myers Squibb Company | Method for administration of buspirone |
US5169638A (en) * | 1991-10-23 | 1992-12-08 | E. R. Squibb & Sons, Inc. | Buoyant controlled release powder formulation |
US5536507A (en) * | 1994-06-24 | 1996-07-16 | Bristol-Myers Squibb Company | Colonic drug delivery system |
WO1997011681A1 (en) * | 1995-09-29 | 1997-04-03 | Lam Pharmaceuticals Inc. | Sustained release delivery system and long acting narcotic analgesics and antagonists |
AU3290397A (en) * | 1996-06-10 | 1998-01-07 | Depomed, Inc. | Gastric-retentive oral controlled drug delivery system with enhanced retention properties |
US6143325A (en) * | 1998-06-05 | 2000-11-07 | Bristol-Myers Squibb Company | Nefazodone dosage form |
-
1999
- 1999-04-26 US US09/299,959 patent/US6143325A/en not_active Expired - Lifetime
- 1999-05-14 ZA ZA9903345A patent/ZA993345B/xx unknown
- 1999-05-19 IL IL13002299A patent/IL130022A0/xx unknown
- 1999-05-28 NZ NZ336001A patent/NZ336001A/xx unknown
- 1999-06-01 SG SG1999002831A patent/SG77244A1/en unknown
- 1999-06-02 PL PL99333524A patent/PL333524A1/xx not_active Application Discontinuation
- 1999-06-03 CA CA002273546A patent/CA2273546A1/en not_active Abandoned
- 1999-06-03 AR ARP990102618A patent/AR018862A1/es unknown
- 1999-06-03 HU HU9901830A patent/HUP9901830A2/hu unknown
- 1999-06-03 NO NO992692A patent/NO992692L/no not_active Application Discontinuation
- 1999-06-04 CO CO99035356A patent/CO5060477A1/es unknown
- 1999-06-04 BR BR9901782-2A patent/BR9901782A/pt not_active IP Right Cessation
- 1999-06-04 EP EP99110777A patent/EP0966966A3/en not_active Withdrawn
- 1999-06-04 PE PE1999000481A patent/PE20000544A1/es not_active Application Discontinuation
- 1999-06-04 ID IDP990521D patent/ID23458A/id unknown
- 1999-06-04 UY UY25544A patent/UY25544A1/es not_active Application Discontinuation
- 1999-06-04 AU AU33199/99A patent/AU3319999A/en not_active Abandoned
- 1999-06-04 KR KR1019990020676A patent/KR20000005930A/ko not_active Application Discontinuation
- 1999-06-04 JP JP11157499A patent/JP2000007567A/ja active Pending
- 1999-06-07 CN CN99108308A patent/CN1238181A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
AU3319999A (en) | 1999-12-16 |
EP0966966A2 (en) | 1999-12-29 |
IL130022A0 (en) | 2000-02-29 |
HU9901830D0 (en) | 1999-07-28 |
CA2273546A1 (en) | 1999-10-10 |
PL333524A1 (en) | 1999-12-06 |
NO992692L (no) | 1999-12-06 |
PE20000544A1 (es) | 2000-06-29 |
HUP9901830A2 (hu) | 2001-06-28 |
NZ336001A (en) | 2000-09-29 |
CN1238181A (zh) | 1999-12-15 |
US6143325A (en) | 2000-11-07 |
UY25544A1 (es) | 2001-08-27 |
KR20000005930A (ko) | 2000-01-25 |
SG77244A1 (en) | 2000-12-19 |
JP2000007567A (ja) | 2000-01-11 |
CO5060477A1 (es) | 2001-07-30 |
EP0966966A3 (en) | 2000-02-09 |
ZA993345B (en) | 2000-08-22 |
ID23458A (id) | 2000-04-27 |
AR018862A1 (es) | 2001-12-12 |
NO992692D0 (no) | 1999-06-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1910 DE 14/08/2007. |