NO20075846L - Laktosefrie, ikke-hygroskopiske og vannfrie farmasoytiske sammensetninger av deskarboetoksyloratadin, samt anvendelse derav ved behandling av sykdommer og forstyrrelser - Google Patents
Laktosefrie, ikke-hygroskopiske og vannfrie farmasoytiske sammensetninger av deskarboetoksyloratadin, samt anvendelse derav ved behandling av sykdommer og forstyrrelserInfo
- Publication number
- NO20075846L NO20075846L NO20075846A NO20075846A NO20075846L NO 20075846 L NO20075846 L NO 20075846L NO 20075846 A NO20075846 A NO 20075846A NO 20075846 A NO20075846 A NO 20075846A NO 20075846 L NO20075846 L NO 20075846L
- Authority
- NO
- Norway
- Prior art keywords
- pharmaceutical compositions
- lactose
- descarboethoxyloratadine
- hygroscopic
- free
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
- A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
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- A—HUMAN NECESSITIES
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- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Stabile farmasøytiske sammensetninger av deskarboetoksyloratadin (DCL), et metabolsk derivat av loratadin, for behandlingen av allergisk rhinitt og andre histamininduserte forstyrrelser er fremlagt. Sammensetningene er formulert for å urmgå inkompatibiliteten mellom DCL og reaktive eksipienter slike som laktose og andre mono- og disakkarider. Fremlagte sammensetninger inkluderer laktosefiie, ikkehygroskopiske og vannfrie stabile farmasøytiske sammensetninger av DCL.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3732597P | 1997-02-07 | 1997-02-07 | |
US4518497P | 1997-04-30 | 1997-04-30 | |
US5305097P | 1997-07-21 | 1997-07-21 | |
PCT/US1998/002328 WO1998034614A1 (en) | 1997-02-07 | 1998-02-06 | Lactose-free, non-hygroscopic and anhydrous pharmaceutical compositions of descarboethoxyloratadine |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20075846L true NO20075846L (no) | 1999-05-04 |
Family
ID=27365195
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19992157A NO325611B1 (no) | 1997-02-07 | 1999-05-04 | Laktosefrie, ikke-hygroskopiske og vannfrie farmasoytiske sammensetninger av deskarboetoksyloratadin, samt anvendelse derav ved behandling av sykdommer og forstyrrelser |
NO20075846A NO20075846L (no) | 1997-02-07 | 2007-11-14 | Laktosefrie, ikke-hygroskopiske og vannfrie farmasoytiske sammensetninger av deskarboetoksyloratadin, samt anvendelse derav ved behandling av sykdommer og forstyrrelser |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19992157A NO325611B1 (no) | 1997-02-07 | 1999-05-04 | Laktosefrie, ikke-hygroskopiske og vannfrie farmasoytiske sammensetninger av deskarboetoksyloratadin, samt anvendelse derav ved behandling av sykdommer og forstyrrelser |
Country Status (29)
Country | Link |
---|---|
US (2) | US20020123504A1 (no) |
EP (2) | EP0969836B1 (no) |
JP (1) | JP2001511184A (no) |
KR (5) | KR20080003012A (no) |
CN (1) | CN1132579C (no) |
AR (3) | AR011114A1 (no) |
AT (1) | ATE345133T1 (no) |
AU (1) | AU6271998A (no) |
BR (1) | BR9806157A (no) |
CA (1) | CA2267136C (no) |
CO (1) | CO4940445A1 (no) |
CZ (1) | CZ119499A3 (no) |
DE (1) | DE69836424T2 (no) |
DK (1) | DK0969836T3 (no) |
ES (1) | ES2271986T3 (no) |
HK (1) | HK1024187A1 (no) |
HU (1) | HUP0001527A3 (no) |
MY (1) | MY136999A (no) |
NO (2) | NO325611B1 (no) |
NZ (1) | NZ335041A (no) |
PE (1) | PE71699A1 (no) |
PL (1) | PL192075B1 (no) |
PT (1) | PT969836E (no) |
RU (1) | RU2209627C2 (no) |
SK (1) | SK286035B6 (no) |
TW (1) | TW522014B (no) |
UA (1) | UA70290C2 (no) |
WO (1) | WO1998034614A1 (no) |
ZA (1) | ZA98977B (no) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
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EP1073438B1 (en) * | 1998-07-10 | 2004-03-31 | Schering Corporation | 8-CHLORO-6,11-DIHYDRO-11-(4-PIPERIDYLIDINE)-5H-BENZO (5,6) CYCLOHEPTA (1,2-b) PYRIDINE ORAL COMPOSITIONS |
US6100274A (en) * | 1999-07-07 | 2000-08-08 | Schering Corporation | 8-chloro-6,11-dihydro-11- ](4-piperidylidine)-5H-benzo[5,6]cyclohepta[1,2-bpyridine oral compositions |
AU7589700A (en) * | 1999-09-22 | 2001-04-24 | Schering Corporation | Treating allergic and inflammatory conditions |
US6114346A (en) | 1999-10-22 | 2000-09-05 | Schering Corporation | Treating sleep disorders using desloratadine |
MY125516A (en) | 1999-11-16 | 2006-08-30 | Smithkline Beecham Plc | Novel composition based on thiazolidinedione and metformin and use |
AU2277101A (en) * | 1999-12-20 | 2001-07-03 | Schering Corporation | Stable extended release oral dosage composition |
SK287105B6 (sk) * | 1999-12-20 | 2009-12-07 | Schering Corporation | Dvojvrstvový orálny dávkový prostriedok s predĺženým uvoľňovaním |
KR101199654B1 (ko) * | 1999-12-20 | 2012-11-08 | 머크 샤프 앤드 돔 코포레이션 | 안정한 서방출형의 경구 투여용 조성물 |
US7405223B2 (en) * | 2000-02-03 | 2008-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
WO2004108700A1 (en) * | 2003-03-12 | 2004-12-16 | Teva Gyogyszergyar Reszvenytarsasag | Processes for preparation of polymorphic forms of desloratadine |
US20060135547A1 (en) * | 2003-03-12 | 2006-06-22 | Toth Zoltan G | Stable pharmaceutical compositions of desloratadine and processes for preparation of polymorphic forms of desloratadine |
US7390503B1 (en) | 2003-08-22 | 2008-06-24 | Barr Laboratories, Inc. | Ondansetron orally disintegrating tablets |
US7955620B2 (en) * | 2003-12-23 | 2011-06-07 | Sun Pharmaceutical Industries Limited | Stable oral composition |
TWI354569B (en) | 2004-05-28 | 2011-12-21 | Bristol Myers Squibb Co | Coated tablet formulation and method |
MX2007000632A (es) * | 2004-07-16 | 2007-03-30 | Cipla Ltd | Composicion antihistaminica. |
US20100129310A1 (en) * | 2004-08-09 | 2010-05-27 | Pavak Rajnikanth Mehta | Stabilized desloratadine composition |
US20070004671A1 (en) * | 2005-05-20 | 2007-01-04 | Agarwal Sudeep K | Stable desloratadine compositions |
CA2547274A1 (en) * | 2005-05-20 | 2006-11-20 | Dr. Reddy's Laboratories Limited | Stable desloratadine compositions |
US20070014855A1 (en) * | 2005-07-12 | 2007-01-18 | Rahul Gawande S | Stable desloratadine compositions |
US20080118555A1 (en) * | 2005-10-20 | 2008-05-22 | Glenmark Pharmaceuticals Limited | Stable pharmaceutical composition containing desloratadine |
CA2541045A1 (en) * | 2006-03-24 | 2007-09-24 | Pharmascience Inc. | A descarbonylethoxyloratadine containing pharmaceutical composition |
EP1862462A1 (en) * | 2006-04-10 | 2007-12-05 | Ranbaxy Laboratories Limited | Process for the preparation of desloratadine |
US20100022576A1 (en) * | 2006-06-07 | 2010-01-28 | Ramaswami Bharatrajan | Stable and bioavailable formulations and a novel form of desloratadine |
ECSP077628A (es) | 2007-05-03 | 2008-12-30 | Smithkline Beechman Corp | Nueva composición farmacéutica |
TR200806298A2 (tr) | 2008-08-22 | 2010-03-22 | Bi̇lgi̇ç Mahmut | Farmasötik formülasyon |
WO2010094471A1 (en) | 2009-02-17 | 2010-08-26 | Krka, D. D., Novo Mesto | Pharmaceutical compositions comprising prasugrel base or its pharmaceutically acceptable acid addition salts and processes for their preparation |
EP2269586B1 (en) | 2009-07-01 | 2011-09-21 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Pharmaceutical composition comprising desloratadine |
WO2011141483A2 (en) | 2010-05-10 | 2011-11-17 | Laboratorios Lesvi, S.L. | Stable pharmaceutical formulations containing an antihistaminic |
TR201009396A2 (tr) | 2010-11-11 | 2012-05-21 | Bi̇lgi̇ç Mahmut | Desloratadin granüller |
CN102813640B (zh) * | 2012-09-06 | 2016-12-21 | 无锡万全医药技术有限公司 | 一种含地氯雷他定的软胶囊及其制备方法 |
US20170135969A1 (en) | 2015-11-12 | 2017-05-18 | Jds Therapeutics, Llc | Topical arginine-silicate-inositol for wound healing |
AU2017318672B2 (en) | 2016-09-01 | 2022-03-10 | Nutrition 21, Llc | Magnesium biotinate compositions and methods of use |
CN113230235B (zh) * | 2021-04-15 | 2022-11-11 | 海南普利制药股份有限公司 | 含地氯雷他定的复方缓释胶囊及其制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1548022A (en) * | 1976-10-06 | 1979-07-04 | Wyeth John & Brother Ltd | Pharmaceutial dosage forms |
JPS61501205A (ja) * | 1984-02-15 | 1986-06-19 | シェリング・コ−ポレ−ション | 8↓−クロル↓−6,11↓−ジヒドロ↓−11↓−(4↓−ピペリジリデン)↓−5H↓−ベンゾ〔5,6〕シクロヘプタ〔1,2−b〕ピリジンおよびその塩、これらの化合物の製造方法、ならびにこれらの化合物を含有する医薬組成物 |
US4990535A (en) * | 1989-05-03 | 1991-02-05 | Schering Corporation | Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine |
EP0563134B1 (en) * | 1990-12-18 | 1996-06-19 | The Wellcome Foundation Limited | Agents for potentiating the effects of antitumor agents and combating multiple drug resistance |
RU2068689C1 (ru) * | 1992-09-24 | 1996-11-10 | Товарищество с ограниченной ответственностью "Лекрон" | Способ получения таблеток парацетамола |
US5314697A (en) * | 1992-10-23 | 1994-05-24 | Schering Corporation | Stable extended release oral dosage composition comprising loratadine and pseudoephedrine |
DE4442999A1 (de) * | 1994-12-02 | 1996-06-05 | Hexal Pharma Gmbh | Pharmazeutische Zusammensetzung mit einem aktiven Loratidin-Metaboliten |
US5595997A (en) * | 1994-12-30 | 1997-01-21 | Sepracor Inc. | Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine |
US5939426A (en) * | 1997-02-28 | 1999-08-17 | Sepracor Inc. | Methods for treating urinary incontinence using descarboethoxyloratadine |
US6162829A (en) * | 1997-10-17 | 2000-12-19 | Atlantic Pharmaceuticals, Inc. | (3R,4R)-Δ8 -tetrahydrocannabinol-11-oic acids useful as antiinflammatory agents and analgesics |
US5997905A (en) * | 1998-09-04 | 1999-12-07 | Mcneil-Ppc | Preparation of pharmaceutically active particles |
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1998
- 1998-02-03 PE PE1998000074A patent/PE71699A1/es not_active Application Discontinuation
- 1998-02-03 TW TW087101236A patent/TW522014B/zh not_active IP Right Cessation
- 1998-02-05 MY MYPI98000458A patent/MY136999A/en unknown
- 1998-02-05 CO CO98005924A patent/CO4940445A1/es unknown
- 1998-02-05 AR ARP980100521A patent/AR011114A1/es not_active Application Discontinuation
- 1998-02-06 WO PCT/US1998/002328 patent/WO1998034614A1/en active Application Filing
- 1998-02-06 KR KR1020077028293A patent/KR20080003012A/ko not_active Application Discontinuation
- 1998-02-06 SK SK472-99A patent/SK286035B6/sk not_active IP Right Cessation
- 1998-02-06 CA CA002267136A patent/CA2267136C/en not_active Expired - Fee Related
- 1998-02-06 KR KR1020077015138A patent/KR20070086880A/ko not_active Application Discontinuation
- 1998-02-06 ES ES98904980T patent/ES2271986T3/es not_active Expired - Lifetime
- 1998-02-06 PT PT98904980T patent/PT969836E/pt unknown
- 1998-02-06 BR BR9806157-7A patent/BR9806157A/pt not_active Application Discontinuation
- 1998-02-06 HU HU0001527A patent/HUP0001527A3/hu unknown
- 1998-02-06 RU RU99107283/14A patent/RU2209627C2/ru not_active IP Right Cessation
- 1998-02-06 EP EP98904980A patent/EP0969836B1/en not_active Revoked
- 1998-02-06 PL PL334232A patent/PL192075B1/pl unknown
- 1998-02-06 KR KR1020067011519A patent/KR20060076330A/ko active Search and Examination
- 1998-02-06 ZA ZA98977A patent/ZA98977B/xx unknown
- 1998-02-06 JP JP53491998A patent/JP2001511184A/ja active Pending
- 1998-02-06 EP EP05108474A patent/EP1614421A3/en not_active Withdrawn
- 1998-02-06 KR KR1020067025791A patent/KR20060132053A/ko not_active Application Discontinuation
- 1998-02-06 NZ NZ335041A patent/NZ335041A/xx not_active IP Right Cessation
- 1998-02-06 AU AU62719/98A patent/AU6271998A/en not_active Abandoned
- 1998-02-06 CN CN98802313XA patent/CN1132579C/zh not_active Expired - Fee Related
- 1998-02-06 KR KR1019997003990A patent/KR100624259B1/ko not_active IP Right Cessation
- 1998-02-06 AT AT98904980T patent/ATE345133T1/de not_active IP Right Cessation
- 1998-02-06 DK DK98904980T patent/DK0969836T3/da active
- 1998-02-06 DE DE69836424T patent/DE69836424T2/de not_active Revoked
- 1998-02-06 CZ CZ991194A patent/CZ119499A3/cs unknown
- 1998-06-02 UA UA99042037A patent/UA70290C2/uk unknown
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1999
- 1999-05-04 NO NO19992157A patent/NO325611B1/no not_active IP Right Cessation
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2000
- 2000-06-20 HK HK00103704A patent/HK1024187A1/xx not_active IP Right Cessation
-
2002
- 2002-02-25 US US10/082,685 patent/US20020123504A1/en not_active Abandoned
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2005
- 2005-12-02 US US11/292,695 patent/US20060079489A1/en not_active Abandoned
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2007
- 2007-11-14 NO NO20075846A patent/NO20075846L/no not_active Application Discontinuation
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2008
- 2008-01-14 AR ARP080100162A patent/AR064896A2/es unknown
- 2008-01-14 AR ARP080100161A patent/AR064895A2/es unknown
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