NO20075270L - Antibakterielle amid-makrocykler V - Google Patents
Antibakterielle amid-makrocykler VInfo
- Publication number
- NO20075270L NO20075270L NO20075270A NO20075270A NO20075270L NO 20075270 L NO20075270 L NO 20075270L NO 20075270 A NO20075270 A NO 20075270A NO 20075270 A NO20075270 A NO 20075270A NO 20075270 L NO20075270 L NO 20075270L
- Authority
- NO
- Norway
- Prior art keywords
- macrocycles
- represents hydrogen
- antibacterial amide
- prophylaxis
- diseases
- Prior art date
Links
- -1 amide macrocycles Chemical class 0.000 title abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 238000011321 prophylaxis Methods 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001721 carbon Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000002678 macrocyclic compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005014245A DE102005014245A1 (de) | 2005-03-30 | 2005-03-30 | Antibakterielle Amid-Makrozyklen V |
| PCT/EP2006/002617 WO2006103015A1 (de) | 2005-03-30 | 2006-03-22 | Antibakterielle amid-makrozyklen v |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20075270L true NO20075270L (no) | 2007-12-18 |
Family
ID=36572224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20075270A NO20075270L (no) | 2005-03-30 | 2007-10-15 | Antibakterielle amid-makrocykler V |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20080275018A1 (OSRAM) |
| EP (1) | EP1869068A1 (OSRAM) |
| JP (1) | JP2008534540A (OSRAM) |
| KR (1) | KR20070116169A (OSRAM) |
| CN (1) | CN101228182A (OSRAM) |
| AU (1) | AU2006228751A1 (OSRAM) |
| BR (1) | BRPI0612219A2 (OSRAM) |
| CA (1) | CA2602755A1 (OSRAM) |
| DE (1) | DE102005014245A1 (OSRAM) |
| IL (1) | IL185899A0 (OSRAM) |
| MX (1) | MX2007012146A (OSRAM) |
| NO (1) | NO20075270L (OSRAM) |
| NZ (1) | NZ562003A (OSRAM) |
| RU (1) | RU2409588C2 (OSRAM) |
| UA (1) | UA91541C2 (OSRAM) |
| WO (1) | WO2006103015A1 (OSRAM) |
| ZA (1) | ZA200709336B (OSRAM) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10358824A1 (de) | 2003-12-16 | 2005-07-21 | Bayer Healthcare Ag | Antibakterielle Makrozyklen mit substituiertem Biphenyl |
| DE102005032781A1 (de) * | 2005-07-14 | 2007-01-18 | Aicuris Gmbh & Co. Kg | Antibakterielle Amid-Markozyklen VII |
| KR20130105659A (ko) | 2010-09-15 | 2013-09-25 | 더 스크립스 리서치 인스티튜트 | 광범위 스펙트럼 항생제 아릴로마이신 유사체 |
| WO2012166665A2 (en) * | 2011-05-27 | 2012-12-06 | Rqx Pharmaceuticals, Inc. | Broad spectrum antibiotics |
| US10501493B2 (en) | 2011-05-27 | 2019-12-10 | Rqx Pharmaceuticals, Inc. | Broad spectrum antibiotics |
| CA2892027A1 (en) | 2012-11-21 | 2014-05-30 | Rqx Pharmaceuticals, Inc. | Macrocyclic broad spectrum antibiotics |
| RU2016146581A (ru) | 2014-05-20 | 2018-06-21 | АрКьюЭкс ФАРМАСЪЮТИКЛС, ИНК. | Макроциклические антибиотики широкого спектра действия |
| CR20180232A (es) | 2015-10-27 | 2018-05-31 | Hoffmann La Roche | Macrociclos peptídicos contra acinetobacter baumannii |
| EP3377474B1 (en) | 2015-11-20 | 2023-08-16 | RQX Pharmaceuticals, Inc. | Macrocyclic broad spectrum antibiotics |
| EP3388444A1 (en) * | 2017-04-10 | 2018-10-17 | F. Hoffmann-La Roche AG | Anti-bacterial peptide macrocycles and use thereof |
| AU2018321548B2 (en) | 2017-08-21 | 2023-03-09 | Celgene Corporation | Processes for preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate |
| US11505573B2 (en) | 2018-03-28 | 2022-11-22 | Hoffmann-La Roche Inc. | Peptide macrocycles against Acinetobacter baumannii |
| US11819532B2 (en) | 2018-04-23 | 2023-11-21 | Hoffmann-La Roche Inc. | Peptide macrocycles against Acinetobacter baumannii |
| IL295889B2 (en) | 2019-05-28 | 2025-01-01 | Hoffmann La Roche | Broad-spectrum macrocyclic antibiotic |
| WO2024262518A1 (ja) * | 2023-06-20 | 2024-12-26 | 国立大学法人北海道大学 | スキャニング用アミノ酸化合物、スキャニング用改変ペプチド、スキャニング用キット及びペプチドの活性部位のスキャニング方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3452136A (en) * | 1968-04-17 | 1969-06-24 | American Cyanamid Co | Antibiotic af283 and production thereof |
| FR2720066B1 (fr) * | 1994-05-20 | 1996-06-28 | Rhone Poulenc Rorer Sa | Peptides antagonistes de la neurotensine. |
| DE10226921A1 (de) * | 2002-06-17 | 2003-12-24 | Bayer Ag | Antibakterielle Amid-Makrozyklen |
| DE10234422A1 (de) * | 2002-07-29 | 2004-02-12 | Bayer Ag | Antibakterielle Ester-Makrozyklen |
| JP2008502583A (ja) * | 2003-10-01 | 2008-01-31 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | 抗細菌性アミド大員環 |
| DE10358824A1 (de) * | 2003-12-16 | 2005-07-21 | Bayer Healthcare Ag | Antibakterielle Makrozyklen mit substituiertem Biphenyl |
| DE102005014240A1 (de) * | 2004-09-24 | 2006-03-30 | Bayer Healthcare Ag | Antibakterielle Amid-Makrozyklen IV |
-
2005
- 2005-03-30 DE DE102005014245A patent/DE102005014245A1/de not_active Withdrawn
-
2006
- 2006-03-22 UA UAA200711765A patent/UA91541C2/ru unknown
- 2006-03-22 BR BRPI0612219-1A patent/BRPI0612219A2/pt not_active IP Right Cessation
- 2006-03-22 RU RU2007139760/04A patent/RU2409588C2/ru not_active IP Right Cessation
- 2006-03-22 MX MX2007012146A patent/MX2007012146A/es not_active Application Discontinuation
- 2006-03-22 JP JP2008503408A patent/JP2008534540A/ja not_active Withdrawn
- 2006-03-22 WO PCT/EP2006/002617 patent/WO2006103015A1/de not_active Ceased
- 2006-03-22 CA CA002602755A patent/CA2602755A1/en not_active Abandoned
- 2006-03-22 ZA ZA200709336A patent/ZA200709336B/xx unknown
- 2006-03-22 NZ NZ562003A patent/NZ562003A/en unknown
- 2006-03-22 AU AU2006228751A patent/AU2006228751A1/en not_active Abandoned
- 2006-03-22 CN CNA2006800188391A patent/CN101228182A/zh active Pending
- 2006-03-22 EP EP06723614A patent/EP1869068A1/de not_active Withdrawn
- 2006-03-22 KR KR1020077025008A patent/KR20070116169A/ko not_active Ceased
-
2007
- 2007-09-11 IL IL185899A patent/IL185899A0/en unknown
- 2007-09-28 US US11/906,088 patent/US20080275018A1/en not_active Abandoned
- 2007-10-15 NO NO20075270A patent/NO20075270L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006103015A1 (de) | 2006-10-05 |
| RU2409588C2 (ru) | 2011-01-20 |
| CA2602755A1 (en) | 2006-10-05 |
| NZ562003A (en) | 2010-11-26 |
| JP2008534540A (ja) | 2008-08-28 |
| AU2006228751A1 (en) | 2006-10-05 |
| KR20070116169A (ko) | 2007-12-06 |
| BRPI0612219A2 (pt) | 2009-01-13 |
| ZA200709336B (en) | 2009-09-30 |
| RU2007139760A (ru) | 2009-05-10 |
| EP1869068A1 (de) | 2007-12-26 |
| US20080275018A1 (en) | 2008-11-06 |
| UA91541C2 (ru) | 2010-08-10 |
| CN101228182A (zh) | 2008-07-23 |
| IL185899A0 (en) | 2008-12-29 |
| MX2007012146A (es) | 2007-12-10 |
| DE102005014245A1 (de) | 2006-10-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |