IL185899A0 - Antibacterial amide-macrocycles v - Google Patents
Antibacterial amide-macrocycles vInfo
- Publication number
- IL185899A0 IL185899A0 IL185899A IL18589907A IL185899A0 IL 185899 A0 IL185899 A0 IL 185899A0 IL 185899 A IL185899 A IL 185899A IL 18589907 A IL18589907 A IL 18589907A IL 185899 A0 IL185899 A0 IL 185899A0
- Authority
- IL
- Israel
- Prior art keywords
- macrocycles
- antibacterial amide
- antibacterial
- amide
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005014245A DE102005014245A1 (de) | 2005-03-30 | 2005-03-30 | Antibakterielle Amid-Makrozyklen V |
| PCT/EP2006/002617 WO2006103015A1 (de) | 2005-03-30 | 2006-03-22 | Antibakterielle amid-makrozyklen v |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL185899A0 true IL185899A0 (en) | 2008-12-29 |
Family
ID=36572224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL185899A IL185899A0 (en) | 2005-03-30 | 2007-09-11 | Antibacterial amide-macrocycles v |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20080275018A1 (OSRAM) |
| EP (1) | EP1869068A1 (OSRAM) |
| JP (1) | JP2008534540A (OSRAM) |
| KR (1) | KR20070116169A (OSRAM) |
| CN (1) | CN101228182A (OSRAM) |
| AU (1) | AU2006228751A1 (OSRAM) |
| BR (1) | BRPI0612219A2 (OSRAM) |
| CA (1) | CA2602755A1 (OSRAM) |
| DE (1) | DE102005014245A1 (OSRAM) |
| IL (1) | IL185899A0 (OSRAM) |
| MX (1) | MX2007012146A (OSRAM) |
| NO (1) | NO20075270L (OSRAM) |
| NZ (1) | NZ562003A (OSRAM) |
| RU (1) | RU2409588C2 (OSRAM) |
| UA (1) | UA91541C2 (OSRAM) |
| WO (1) | WO2006103015A1 (OSRAM) |
| ZA (1) | ZA200709336B (OSRAM) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10358824A1 (de) | 2003-12-16 | 2005-07-21 | Bayer Healthcare Ag | Antibakterielle Makrozyklen mit substituiertem Biphenyl |
| DE102005032781A1 (de) * | 2005-07-14 | 2007-01-18 | Aicuris Gmbh & Co. Kg | Antibakterielle Amid-Markozyklen VII |
| KR20130105659A (ko) | 2010-09-15 | 2013-09-25 | 더 스크립스 리서치 인스티튜트 | 광범위 스펙트럼 항생제 아릴로마이신 유사체 |
| WO2012166665A2 (en) * | 2011-05-27 | 2012-12-06 | Rqx Pharmaceuticals, Inc. | Broad spectrum antibiotics |
| US10501493B2 (en) | 2011-05-27 | 2019-12-10 | Rqx Pharmaceuticals, Inc. | Broad spectrum antibiotics |
| EP2922829B1 (en) | 2012-11-21 | 2021-08-11 | RQX Pharmaceuticals, Inc. | Macrocyclic broad spectrum antibiotics |
| WO2015179441A2 (en) | 2014-05-20 | 2015-11-26 | Rqx Pharmaceuticals, Inc. | Macrocyclic broad spectrum antibiotics |
| RS60662B1 (sr) | 2015-10-27 | 2020-09-30 | Hoffmann La Roche | Peptidni makrocikli protiv acinetobacter baumannii |
| CN109219596B (zh) | 2015-11-20 | 2022-04-19 | 阿奇克斯制药公司 | 大环广谱抗生素 |
| EP3388444A1 (en) * | 2017-04-10 | 2018-10-17 | F. Hoffmann-La Roche AG | Anti-bacterial peptide macrocycles and use thereof |
| CN118638025A (zh) | 2017-08-21 | 2024-09-13 | 细胞基因公司 | 制备(s)-4,5-二氨基-5-氧代戊酸叔丁酯的工艺 |
| US11505573B2 (en) | 2018-03-28 | 2022-11-22 | Hoffmann-La Roche Inc. | Peptide macrocycles against Acinetobacter baumannii |
| US11819532B2 (en) | 2018-04-23 | 2023-11-21 | Hoffmann-La Roche Inc. | Peptide macrocycles against Acinetobacter baumannii |
| SI3968983T1 (sl) | 2019-05-28 | 2023-11-30 | F. Hoffmann - La Roche Ag | Makrociklični antibiotiki širokega spektra |
| WO2024262518A1 (ja) * | 2023-06-20 | 2024-12-26 | 国立大学法人北海道大学 | スキャニング用アミノ酸化合物、スキャニング用改変ペプチド、スキャニング用キット及びペプチドの活性部位のスキャニング方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3452136A (en) * | 1968-04-17 | 1969-06-24 | American Cyanamid Co | Antibiotic af283 and production thereof |
| FR2720066B1 (fr) * | 1994-05-20 | 1996-06-28 | Rhone Poulenc Rorer Sa | Peptides antagonistes de la neurotensine. |
| DE10226921A1 (de) * | 2002-06-17 | 2003-12-24 | Bayer Ag | Antibakterielle Amid-Makrozyklen |
| DE10234422A1 (de) * | 2002-07-29 | 2004-02-12 | Bayer Ag | Antibakterielle Ester-Makrozyklen |
| JP2008502583A (ja) * | 2003-10-01 | 2008-01-31 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | 抗細菌性アミド大員環 |
| DE10358824A1 (de) * | 2003-12-16 | 2005-07-21 | Bayer Healthcare Ag | Antibakterielle Makrozyklen mit substituiertem Biphenyl |
| DE102005014240A1 (de) * | 2004-09-24 | 2006-03-30 | Bayer Healthcare Ag | Antibakterielle Amid-Makrozyklen IV |
-
2005
- 2005-03-30 DE DE102005014245A patent/DE102005014245A1/de not_active Withdrawn
-
2006
- 2006-03-22 UA UAA200711765A patent/UA91541C2/ru unknown
- 2006-03-22 RU RU2007139760/04A patent/RU2409588C2/ru not_active IP Right Cessation
- 2006-03-22 ZA ZA200709336A patent/ZA200709336B/xx unknown
- 2006-03-22 WO PCT/EP2006/002617 patent/WO2006103015A1/de not_active Ceased
- 2006-03-22 MX MX2007012146A patent/MX2007012146A/es not_active Application Discontinuation
- 2006-03-22 CN CNA2006800188391A patent/CN101228182A/zh active Pending
- 2006-03-22 KR KR1020077025008A patent/KR20070116169A/ko not_active Ceased
- 2006-03-22 JP JP2008503408A patent/JP2008534540A/ja not_active Withdrawn
- 2006-03-22 CA CA002602755A patent/CA2602755A1/en not_active Abandoned
- 2006-03-22 BR BRPI0612219-1A patent/BRPI0612219A2/pt not_active IP Right Cessation
- 2006-03-22 EP EP06723614A patent/EP1869068A1/de not_active Withdrawn
- 2006-03-22 NZ NZ562003A patent/NZ562003A/en unknown
- 2006-03-22 AU AU2006228751A patent/AU2006228751A1/en not_active Abandoned
-
2007
- 2007-09-11 IL IL185899A patent/IL185899A0/en unknown
- 2007-09-28 US US11/906,088 patent/US20080275018A1/en not_active Abandoned
- 2007-10-15 NO NO20075270A patent/NO20075270L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20080275018A1 (en) | 2008-11-06 |
| KR20070116169A (ko) | 2007-12-06 |
| NO20075270L (no) | 2007-12-18 |
| UA91541C2 (ru) | 2010-08-10 |
| RU2007139760A (ru) | 2009-05-10 |
| DE102005014245A1 (de) | 2006-10-05 |
| MX2007012146A (es) | 2007-12-10 |
| NZ562003A (en) | 2010-11-26 |
| RU2409588C2 (ru) | 2011-01-20 |
| JP2008534540A (ja) | 2008-08-28 |
| WO2006103015A1 (de) | 2006-10-05 |
| CA2602755A1 (en) | 2006-10-05 |
| EP1869068A1 (de) | 2007-12-26 |
| AU2006228751A1 (en) | 2006-10-05 |
| BRPI0612219A2 (pt) | 2009-01-13 |
| CN101228182A (zh) | 2008-07-23 |
| ZA200709336B (en) | 2009-09-30 |
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