NO20074874L - Amorf lerkanidipinhydroklorid - Google Patents
Amorf lerkanidipinhydrokloridInfo
- Publication number
- NO20074874L NO20074874L NO20074874A NO20074874A NO20074874L NO 20074874 L NO20074874 L NO 20074874L NO 20074874 A NO20074874 A NO 20074874A NO 20074874 A NO20074874 A NO 20074874A NO 20074874 L NO20074874 L NO 20074874L
- Authority
- NO
- Norway
- Prior art keywords
- amorphous lercanidipine
- lercanidipine hydrochloride
- approx
- substantially pure
- pure amorphous
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B63/00—Purification; Separation; Stabilisation; Use of additives
- C07B63/04—Use of additives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
Abstract
Oppfinnelsen tilveiebringer et stort sett rent amorft lerkanidipinhydroklorid som har en renhet på minst 95 %, fortrinnsvis minst ca. 97 %, mer foretrukket minst ca. 99 % og enda mer foretrukket minst ca. 99,5 %. Oppfinnelsen tilveiebringer videre fremgangsmåte for fremstilling av stort sett rent amorft lerkanidipin og farmasøytiske sammensetninger inneholdende det stort sett rene amorfe lerkanidipinet.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65683605P | 2005-02-25 | 2005-02-25 | |
PCT/EP2006/001782 WO2006089787A1 (en) | 2005-02-25 | 2006-02-24 | Amorphous lercanidipine hydrochloride |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20074874L true NO20074874L (no) | 2007-11-26 |
NO344559B1 NO344559B1 (no) | 2020-02-03 |
Family
ID=36585434
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20074874A NO344559B1 (no) | 2005-02-25 | 2007-09-25 | Amorf lerkanidipinhydroklorid |
Country Status (32)
Country | Link |
---|---|
US (1) | US7820701B2 (no) |
EP (1) | EP1856051B1 (no) |
JP (1) | JP2008531515A (no) |
KR (1) | KR20070105979A (no) |
CN (1) | CN101124204A (no) |
AR (1) | AR052918A1 (no) |
AU (1) | AU2006218026B9 (no) |
BR (1) | BRPI0608138A2 (no) |
CA (1) | CA2598016A1 (no) |
CY (1) | CY1122429T1 (no) |
DK (1) | DK1856051T3 (no) |
EA (1) | EA014383B1 (no) |
ES (1) | ES2339213T3 (no) |
HR (1) | HRP20192302T1 (no) |
HU (1) | HUE046910T2 (no) |
IL (1) | IL184349A0 (no) |
LT (1) | LT1856051T (no) |
ME (1) | ME03659B (no) |
MX (1) | MX2007010093A (no) |
MY (1) | MY142129A (no) |
NO (1) | NO344559B1 (no) |
NZ (1) | NZ556667A (no) |
PE (1) | PE20061014A1 (no) |
PL (1) | PL1856051T3 (no) |
PT (1) | PT1856051T (no) |
RS (1) | RS59654B1 (no) |
SI (1) | SI1856051T1 (no) |
TW (1) | TW200640861A (no) |
UA (1) | UA90130C2 (no) |
UY (1) | UY29401A1 (no) |
WO (1) | WO2006089787A1 (no) |
ZA (1) | ZA200708127B (no) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1532248B1 (en) | 2002-07-26 | 2009-04-01 | Novartis Vaccines and Diagnostics, Inc. | Modified small interfering rna molecules and methods of use |
AR052918A1 (es) | 2005-02-25 | 2007-04-11 | Recordati Ireland Ltd | Clorhidrato de lercanidipina amorfo |
KR20080048065A (ko) | 2005-09-16 | 2008-05-30 | 그렌마크 파머수티칼스 엘티디. | 다형 형태의 염산 레르카니디핀 및 이것의 제조방법 |
DK2046745T3 (da) * | 2006-08-04 | 2014-01-20 | Recordati Ireland Ltd | Fremgangsmåde til fremstilling af amorft lercanidipin-hydrochlorid |
EP2101771A2 (en) * | 2006-12-06 | 2009-09-23 | Torrent Pharmaceuticals Ltd | Stable lercanidipine formulation |
EP2121575A2 (en) * | 2007-03-05 | 2009-11-25 | Actavis Group PTC EHF | Lercanidipine hydrochloride polymorphs and an improved process for preparation of 1,1,n-trimethyl-n-(3,3-diphenylpropyl)-2-aminoethyl acetoacetate |
ES2531040T3 (es) * | 2009-05-12 | 2015-03-10 | Corcept Therapeutics Inc | Formas sólidas y procedimiento de preparación |
DE102010005124A1 (de) * | 2010-01-19 | 2012-03-01 | Stada Arzneimittel Ag | Feste pharmazeutische Zusammensetzung umfassend Lercanidipin |
EP2444394A1 (en) | 2010-10-21 | 2012-04-25 | Alembic Pharmaceuticals Limited | Process for the preparation of amorphous form of lercanidipine HCI |
CN102558032B (zh) * | 2011-12-16 | 2014-02-26 | 华润赛科药业有限责任公司 | 一种无定形盐酸乐卡地平及其制备方法 |
CN102531999B (zh) * | 2011-12-16 | 2014-02-26 | 华润赛科药业有限责任公司 | 无定形盐酸乐卡地平及其制备方法 |
CN102600146B (zh) * | 2012-04-11 | 2014-10-08 | 兆科药业(合肥)有限公司 | 一种盐酸乐卡地平和氯沙坦钾复方制剂及其制备方法 |
EP3039011A1 (en) * | 2013-08-29 | 2016-07-06 | Cadila Healthcare Limited | Polymorphic form of pyrrole derivative and intermediate thereof |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8403866D0 (en) * | 1984-02-14 | 1984-03-21 | Recordati Chem Pharm | Diphenylalkylaminoalkyl esters |
IT1274480B (it) | 1995-05-12 | 1997-07-17 | Recordati Chem Pharm | Procedimento migliorato per la preparazione della lercanidipina cloridrato |
US5912351A (en) | 1995-05-12 | 1999-06-15 | Recordati, S.A. Chemical And Pharmaceutical Company | Anhydrous 1,4-Dihydropyridines and salts thereof |
US5696139A (en) * | 1995-05-12 | 1997-12-09 | Recordati S.A., Chemical And Pharmaceutical Company | Use of S-enantiomers of 1,4-dihydropyridine derivatives for treating heart failure |
ITMI20011726A1 (it) | 2001-08-06 | 2003-02-06 | Recordati Ind Chimica E Farma | Forme polimorfe della lercanidipina cloridrato |
US6852737B2 (en) * | 2001-08-06 | 2005-02-08 | Recordati Ireland Limited | Crude and crystalline forms of lercanidipine hydrochloride |
ITMI20011727A1 (it) | 2001-08-06 | 2003-02-06 | Recordati Ind Chimica E Farma | Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi |
US20030069285A1 (en) * | 2001-08-06 | 2003-04-10 | Recordati Ireland Limited | Novel solvate and crystalline forms of lercanidipine hydrochloride |
US20030180355A1 (en) * | 2001-10-16 | 2003-09-25 | Amedeo Leonardi | Combination therapy for hypertension |
JP4749660B2 (ja) * | 2002-10-16 | 2011-08-17 | 武田薬品工業株式会社 | 安定な固形製剤 |
US20040147566A1 (en) * | 2002-10-16 | 2004-07-29 | Amedeo Leonardi | Lisinopril/lercanidipine combination therapy |
US20040198789A1 (en) * | 2003-02-28 | 2004-10-07 | Recordati Ireland Limited | Lercanidipine/ARB/diuretic therapeutic combinations |
TW200613275A (en) * | 2004-08-24 | 2006-05-01 | Recordati Ireland Ltd | Lercanidipine salts |
TW200616681A (en) | 2004-10-05 | 2006-06-01 | Recordati Ireland Ltd | Lercanidipine capsules |
KR100651212B1 (ko) | 2004-10-27 | 2006-12-01 | 제일약품주식회사 | 무정형 레르카니디핀의 제조방법 |
AR052918A1 (es) | 2005-02-25 | 2007-04-11 | Recordati Ireland Ltd | Clorhidrato de lercanidipina amorfo |
KR20080048065A (ko) | 2005-09-16 | 2008-05-30 | 그렌마크 파머수티칼스 엘티디. | 다형 형태의 염산 레르카니디핀 및 이것의 제조방법 |
EP1963254A2 (en) | 2005-09-21 | 2008-09-03 | Torrent Pharmaceuticals Ltd | Process for the preparation of lercanidipine and amorphous form of lercanidipine hydrochloride |
DK2046745T3 (da) | 2006-08-04 | 2014-01-20 | Recordati Ireland Ltd | Fremgangsmåde til fremstilling af amorft lercanidipin-hydrochlorid |
-
2006
- 2006-02-22 AR ARP060100641A patent/AR052918A1/es not_active Application Discontinuation
- 2006-02-24 ME MEP-2019-352A patent/ME03659B/me unknown
- 2006-02-24 PT PT67231282T patent/PT1856051T/pt unknown
- 2006-02-24 UA UAA200709786A patent/UA90130C2/ru unknown
- 2006-02-24 PL PL06723128T patent/PL1856051T3/pl unknown
- 2006-02-24 JP JP2007556565A patent/JP2008531515A/ja active Pending
- 2006-02-24 KR KR1020077017758A patent/KR20070105979A/ko not_active Application Discontinuation
- 2006-02-24 UY UY29401A patent/UY29401A1/es not_active Application Discontinuation
- 2006-02-24 EP EP06723128.2A patent/EP1856051B1/en not_active Revoked
- 2006-02-24 SI SI200632364T patent/SI1856051T1/sl unknown
- 2006-02-24 HU HUE06723128A patent/HUE046910T2/hu unknown
- 2006-02-24 CN CNA2006800054950A patent/CN101124204A/zh active Pending
- 2006-02-24 RS RS20191591A patent/RS59654B1/sr unknown
- 2006-02-24 ES ES06723128T patent/ES2339213T3/es active Active
- 2006-02-24 PE PE2006000224A patent/PE20061014A1/es active IP Right Grant
- 2006-02-24 MY MYPI20060808A patent/MY142129A/en unknown
- 2006-02-24 BR BRPI0608138-0A patent/BRPI0608138A2/pt not_active Application Discontinuation
- 2006-02-24 AU AU2006218026A patent/AU2006218026B9/en not_active Ceased
- 2006-02-24 DK DK06723128.2T patent/DK1856051T3/da active
- 2006-02-24 EA EA200701687A patent/EA014383B1/ru unknown
- 2006-02-24 WO PCT/EP2006/001782 patent/WO2006089787A1/en active Application Filing
- 2006-02-24 LT LTEP06723128.2T patent/LT1856051T/lt unknown
- 2006-02-24 TW TW095106337A patent/TW200640861A/zh unknown
- 2006-02-24 MX MX2007010093A patent/MX2007010093A/es not_active Application Discontinuation
- 2006-02-24 CA CA002598016A patent/CA2598016A1/en not_active Abandoned
- 2006-02-24 NZ NZ556667A patent/NZ556667A/en not_active IP Right Cessation
- 2006-02-27 US US11/364,862 patent/US7820701B2/en active Active
-
2007
- 2007-07-02 IL IL184349A patent/IL184349A0/en active IP Right Grant
- 2007-09-21 ZA ZA200708127A patent/ZA200708127B/xx unknown
- 2007-09-25 NO NO20074874A patent/NO344559B1/no not_active IP Right Cessation
-
2019
- 2019-12-18 CY CY20191101332T patent/CY1122429T1/el unknown
- 2019-12-20 HR HRP20192302TT patent/HRP20192302T1/hr unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20074874L (no) | Amorf lerkanidipinhydroklorid | |
ATE465719T1 (de) | Oral zerfallende zusammensetzung von olanzapin oder donepezil | |
NO20081729L (no) | Nye diazaspiroalkaner og deres anvendelse for behandling av CCR8-medierte sykdommer | |
CY1117051T1 (el) | Φαρμακευτικες συνθεσεις που περιεχουν κρυσταλλικη μορφη (i) της υδροχλωριουχου λερκανιδιπινης | |
AP1830A (en) | Polymorphous form of rimonabant, preparation method and pharmaceutical compositions containing same. | |
NO20092412L (no) | Hydantoinderivater anvendes som MMP-inhibitorer | |
WO2004096128A3 (en) | Hiv integrase inhibitors | |
NO20062021L (no) | Omleirede pentanoler, fremgangsmpte for fremstilling av dette, og deres anvendelse som antiflogistika | |
NO20072494L (no) | Fast farmasoytisk forbindelse som omfatter donepezil-hydroklorid | |
NO20052683D0 (no) | Nye pyridopyrimidinonforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem | |
NO20064344L (no) | Caspaseinhibitorer og anvendelser derav | |
NO20073572L (no) | Nye forbindelser | |
NO20073571L (no) | Nye hydantoinderivater som metallproteinaseinhibitorer | |
NO20071372L (no) | Nye polymorfer av azabisykloheksan | |
NO20071012L (no) | Fremgangsmate for fremstilling av D-erytro-2,2-difluor-2-deoksy-1-oksoribosederivat | |
DE602004008959D1 (de) | Benzoäbüä1,4üdioxepinderivate | |
DK1971216T4 (da) | Tyggegummi indeholdende styren-dien-blokcopolymerer | |
TW200508195A (en) | 3-aminopyrrolidines as inhibitors of monoamine uptake | |
NO20074873L (no) | Lerkanidipinfri base | |
NO20074259L (no) | Fremgangsmate for fremstilling av substituerte benzoksazolforbindelser | |
GEP20094603B (en) | NEW ASSOCIATION OF A SINUS CURRENT if INHIBITOR AND A CALCIC INHIBITOR, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | |
WO2005007642A3 (en) | Novel azaheterocyclic amides useful for treating pain | |
TW200716537A (en) | Polymorphic form of dexketoprofen trometamol, its preparation and compositions containing it | |
NO20083521L (no) | Rimonabantmonohydrat, fremgangsmate for fremstilling derav og farmasoytiske sammensetninger inneholdende samme | |
MX2008002073A (es) | Compuestos para el tratamiento de trastornos inflamatorios. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |