NO20063647L - Nye inhibitorer av chymase - Google Patents

Nye inhibitorer av chymase

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Publication number
NO20063647L
NO20063647L NO20063647A NO20063647A NO20063647L NO 20063647 L NO20063647 L NO 20063647L NO 20063647 A NO20063647 A NO 20063647A NO 20063647 A NO20063647 A NO 20063647A NO 20063647 L NO20063647 L NO 20063647L
Authority
NO
Norway
Prior art keywords
chymase
new inhibitors
methods
intermediates
derivatives
Prior art date
Application number
NO20063647A
Other languages
English (en)
Norwegian (no)
Inventor
Michael Nicholas Greco
Bruce E Maryanoff
Lawrence De Garavilla
Michael J Hawkins
Eugene Powell
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20063647L publication Critical patent/NO20063647L/no

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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
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    • C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
    • C07F9/655354—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems
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    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
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NO20063647A 2004-01-23 2006-08-11 Nye inhibitorer av chymase NO20063647L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53866304P 2004-01-23 2004-01-23
PCT/US2005/001659 WO2005073214A2 (en) 2004-01-23 2005-01-18 Novel inhibitors of chymase

Publications (1)

Publication Number Publication Date
NO20063647L true NO20063647L (no) 2006-10-19

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NO20063647A NO20063647L (no) 2004-01-23 2006-08-11 Nye inhibitorer av chymase

Country Status (24)

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US (2) US7459444B2 (ja)
EP (1) EP1716160B1 (ja)
JP (1) JP5022711B2 (ja)
KR (1) KR101182143B1 (ja)
CN (2) CN1934120B (ja)
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CN101827599B (zh) * 2007-10-16 2013-08-28 詹森药业有限公司 用于合成膦酸和次膦酸化合物的方法
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JP5587914B2 (ja) 2009-01-30 2014-09-10 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング キマーゼ阻害剤として有用なアザキナゾリンジオン
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CN107573263B (zh) * 2017-08-14 2020-04-07 大连理工大学 一种ω-取代缩二脲类化合物的合成方法
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CN115873037A (zh) * 2022-11-30 2023-03-31 南通大学 一种膦化氮杂吲哚啉的合成方法

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US20050176769A1 (en) 2005-08-11
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CN1934120B (zh) 2010-05-26
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ATE493421T1 (de) 2011-01-15
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EA011745B1 (ru) 2009-06-30
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IL177037A (en) 2013-05-30
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