NO20063452L - Benzamid-derivater og deres anvendelse som glukokinaseaktiversingsmidler - Google Patents
Benzamid-derivater og deres anvendelse som glukokinaseaktiversingsmidlerInfo
- Publication number
- NO20063452L NO20063452L NO20063452A NO20063452A NO20063452L NO 20063452 L NO20063452 L NO 20063452L NO 20063452 A NO20063452 A NO 20063452A NO 20063452 A NO20063452 A NO 20063452A NO 20063452 L NO20063452 L NO 20063452L
- Authority
- NO
- Norway
- Prior art keywords
- het
- optionally substituted
- membered
- linked
- heterocyclyl ring
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0403593A GB0403593D0 (en) | 2004-02-18 | 2004-02-18 | Compounds |
GB0413386A GB0413386D0 (en) | 2004-06-16 | 2004-06-16 | Compounds |
GB0423039A GB0423039D0 (en) | 2004-10-16 | 2004-10-16 | Compounds |
PCT/GB2005/000545 WO2005080359A1 (en) | 2004-02-18 | 2005-02-15 | Benzamide derivatives and their use as glucokinae activating agents |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20063452L true NO20063452L (no) | 2006-10-31 |
Family
ID=34890799
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20063452A NO20063452L (no) | 2004-02-18 | 2006-07-26 | Benzamid-derivater og deres anvendelse som glukokinaseaktiversingsmidler |
Country Status (18)
Country | Link |
---|---|
US (2) | US20080280872A1 (uk) |
EP (2) | EP2048137A1 (uk) |
JP (1) | JP2007523142A (uk) |
KR (1) | KR20070007103A (uk) |
AR (1) | AR047678A1 (uk) |
AT (1) | ATE426597T1 (uk) |
AU (1) | AU2005214132B9 (uk) |
BR (1) | BRPI0507746A (uk) |
CA (1) | CA2554310A1 (uk) |
DE (1) | DE602005013491D1 (uk) |
ES (1) | ES2322709T3 (uk) |
HK (1) | HK1096092A1 (uk) |
IL (1) | IL177216A0 (uk) |
NO (1) | NO20063452L (uk) |
RU (1) | RU2392275C2 (uk) |
TW (1) | TW200602028A (uk) |
UY (1) | UY28756A1 (uk) |
WO (1) | WO2005080359A1 (uk) |
Families Citing this family (38)
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SE0102299D0 (sv) | 2001-06-26 | 2001-06-26 | Astrazeneca Ab | Compounds |
GB0226931D0 (en) | 2002-11-19 | 2002-12-24 | Astrazeneca Ab | Chemical compounds |
JP4400563B2 (ja) | 2003-02-13 | 2010-01-20 | 萬有製薬株式会社 | 新規2−ピリジンカルボキサミド誘導体 |
JP4432901B2 (ja) * | 2003-02-26 | 2010-03-17 | 萬有製薬株式会社 | ヘテロアリールカルバモイルベンゼン誘導体 |
US20080280872A1 (en) * | 2004-02-18 | 2008-11-13 | Craig Johnstone | Benzamide Derivatives and Their Use as Glucokinase Activating Agents |
TW200600086A (en) * | 2004-06-05 | 2006-01-01 | Astrazeneca Ab | Chemical compound |
GB0423043D0 (en) * | 2004-10-16 | 2004-11-17 | Astrazeneca Ab | Compounds |
GB0423042D0 (en) * | 2004-10-16 | 2004-11-17 | Astrazeneca Ab | Chemical process |
GB0423044D0 (en) * | 2004-10-16 | 2004-11-17 | Astrazeneca Ab | Compounds |
KR20070085371A (ko) * | 2004-10-16 | 2007-08-27 | 아스트라제네카 아베 | 페녹시 벤즈아미드 화합물의 제조 방법 |
TW200714597A (en) * | 2005-05-27 | 2007-04-16 | Astrazeneca Ab | Chemical compounds |
JP4651714B2 (ja) * | 2005-07-09 | 2011-03-16 | アストラゼネカ アクチボラグ | 糖尿病の治療においてglk活性化剤として使用するためのヘテロアリールベンズアミド誘導体 |
CA2624102A1 (en) | 2005-09-29 | 2007-04-12 | Sanofi-Aventis | Phenyl- and pyridinyl- 1, 2 , 4 - oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals |
JP2009515997A (ja) * | 2005-11-18 | 2009-04-16 | タケダ サン ディエゴ インコーポレイテッド | グルコキナーゼ活性剤 |
TW200738621A (en) * | 2005-11-28 | 2007-10-16 | Astrazeneca Ab | Chemical process |
PE20110235A1 (es) | 2006-05-04 | 2011-04-14 | Boehringer Ingelheim Int | Combinaciones farmaceuticas que comprenden linagliptina y metmorfina |
US7910747B2 (en) | 2006-07-06 | 2011-03-22 | Bristol-Myers Squibb Company | Phosphonate and phosphinate pyrazolylamide glucokinase activators |
EP2261216A3 (en) | 2006-07-24 | 2011-12-14 | F. Hoffmann-La Roche AG | Pyrazoles as glucokinase activators |
TW200825060A (en) * | 2006-10-26 | 2008-06-16 | Astrazeneca Ab | Chemical compounds |
CA2671535A1 (en) * | 2006-12-21 | 2008-06-26 | Astrazeneca Ab | Novel crystalline compound useful as glk activator |
JP2010534722A (ja) | 2007-07-27 | 2010-11-11 | ブリストル−マイヤーズ スクイブ カンパニー | 新規グルコキナーゼ活性化薬およびその使用方法 |
PT2197849E (pt) | 2007-10-09 | 2013-04-23 | Merck Patent Gmbh | Derivados de n-(pirazole-3-il)-benzamida como ativadores de glucoquinase |
DK2239253T3 (da) | 2008-02-06 | 2013-09-23 | Daiichi Sankyo Co Ltd | Hidtil ukendt phenylpyrrolderivat |
US20110009437A1 (en) * | 2008-02-27 | 2011-01-13 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Carboxamide-heteroaryl derivatives for the treatment of diabetes |
US8258134B2 (en) | 2008-04-16 | 2012-09-04 | Hoffmann-La Roche Inc. | Pyridazinone glucokinase activators |
US7741327B2 (en) | 2008-04-16 | 2010-06-22 | Hoffmann-La Roche Inc. | Pyrrolidinone glucokinase activators |
CN102171213A (zh) | 2008-08-04 | 2011-08-31 | 阿斯利康(瑞典)有限公司 | 吡唑并[3,4]嘧啶-4-基衍生物及其治疗糖尿病和肥胖症的用途 |
WO2010082601A1 (ja) * | 2009-01-16 | 2010-07-22 | 第一三共株式会社 | 新規2,5-二置換ピロール誘導体 |
GB0902434D0 (en) * | 2009-02-13 | 2009-04-01 | Astrazeneca Ab | Chemical process |
GB0902406D0 (en) * | 2009-02-13 | 2009-04-01 | Astrazeneca Ab | Crystalline polymorphic form |
AR076221A1 (es) * | 2009-04-09 | 2011-05-26 | Astrazeneca Ab | Derivado de pirazol [4,5-e] pirimidina y su uso para tratar diabetes y obesidad |
WO2010116177A1 (en) | 2009-04-09 | 2010-10-14 | Astrazeneca Ab | A pyrazolo [4,5-e] pyrimidine derivative and its use to treat diabetes and obesity |
WO2010128595A1 (ja) * | 2009-05-07 | 2010-11-11 | 富士フイルムRiファーマ株式会社 | 放射性ヨウ素標識イミダゾピリジン誘導体の製造法 |
US8450494B2 (en) | 2009-06-22 | 2013-05-28 | Cadila Healthcare Limited | Disubstituted benzamide derivatives as glucokinase (GK) activators |
DK2459554T3 (da) | 2009-07-31 | 2014-01-06 | Cadila Healthcare Ltd | Substituerede benzamidderivater som glucokinase (GK)-aktivatorer |
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US8222416B2 (en) | 2009-12-14 | 2012-07-17 | Hoffmann-La Roche Inc. | Azaindole glucokinase activators |
WO2011122458A1 (ja) * | 2010-03-29 | 2011-10-06 | 第一三共株式会社 | 含窒素芳香環化合物 |
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BR0115999A (pt) * | 2000-12-06 | 2003-09-30 | Hoffmann La Roche | Composto, composição farmacêutica que compreende o mesmo, sua utilização, processo para o tratamento profilático ou terapêutico de diabetes do tipo ii e processo para a preparação do composto |
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SE0102300D0 (sv) * | 2001-06-26 | 2001-06-26 | Astrazeneca Ab | Compounds |
SE0102299D0 (sv) * | 2001-06-26 | 2001-06-26 | Astrazeneca Ab | Compounds |
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SE0102764D0 (sv) * | 2001-08-17 | 2001-08-17 | Astrazeneca Ab | Compounds |
DE10161765A1 (de) * | 2001-12-15 | 2003-07-03 | Bayer Cropscience Gmbh | Substituierte Phenylderivate |
WO2003055482A1 (en) | 2001-12-21 | 2003-07-10 | Novo Nordisk A/S | Amide derivatives as gk activators |
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GB0226930D0 (en) * | 2002-11-19 | 2002-12-24 | Astrazeneca Ab | Chemical compounds |
JP4432901B2 (ja) * | 2003-02-26 | 2010-03-17 | 萬有製薬株式会社 | ヘテロアリールカルバモイルベンゼン誘導体 |
GB0325402D0 (en) * | 2003-10-31 | 2003-12-03 | Astrazeneca Ab | Compounds |
WO2005048948A2 (en) * | 2003-11-13 | 2005-06-02 | Ambit Biosciences Corporation | Urea derivatives as kinase modulators |
GB0327761D0 (en) * | 2003-11-29 | 2003-12-31 | Astrazeneca Ab | Compounds |
GB0327760D0 (en) * | 2003-11-29 | 2003-12-31 | Astrazeneca Ab | Compounds |
GB0328178D0 (en) * | 2003-12-05 | 2004-01-07 | Astrazeneca Ab | Compounds |
US20080280872A1 (en) * | 2004-02-18 | 2008-11-13 | Craig Johnstone | Benzamide Derivatives and Their Use as Glucokinase Activating Agents |
BRPI0507734A (pt) * | 2004-02-18 | 2007-07-10 | Astrazeneca Ab | composto ou um sal, pró-droga ou solvato do mesmo, método de tratar doenças mediadas por glk, e, processo para a preparação de um composto |
TW200600086A (en) * | 2004-06-05 | 2006-01-01 | Astrazeneca Ab | Chemical compound |
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GB0423043D0 (en) * | 2004-10-16 | 2004-11-17 | Astrazeneca Ab | Compounds |
GB0423044D0 (en) * | 2004-10-16 | 2004-11-17 | Astrazeneca Ab | Compounds |
KR20070085371A (ko) * | 2004-10-16 | 2007-08-27 | 아스트라제네카 아베 | 페녹시 벤즈아미드 화합물의 제조 방법 |
TW200714597A (en) * | 2005-05-27 | 2007-04-16 | Astrazeneca Ab | Chemical compounds |
JP4651714B2 (ja) * | 2005-07-09 | 2011-03-16 | アストラゼネカ アクチボラグ | 糖尿病の治療においてglk活性化剤として使用するためのヘテロアリールベンズアミド誘導体 |
US20080234273A1 (en) * | 2005-07-09 | 2008-09-25 | Mckerrecher Darren | Heteroaryl Benzamide Derivatives for Use as Glk Activators in the Treatment of Diabetes |
EP1928874A1 (en) * | 2005-09-16 | 2008-06-11 | AstraZeneca AB | Heterobicyclic compounds as glucokinase activators |
TW200738621A (en) * | 2005-11-28 | 2007-10-16 | Astrazeneca Ab | Chemical process |
TW200825063A (en) * | 2006-10-23 | 2008-06-16 | Astrazeneca Ab | Chemical compounds |
TW200825060A (en) * | 2006-10-26 | 2008-06-16 | Astrazeneca Ab | Chemical compounds |
CA2671535A1 (en) * | 2006-12-21 | 2008-06-26 | Astrazeneca Ab | Novel crystalline compound useful as glk activator |
-
2005
- 2005-02-15 US US10/588,334 patent/US20080280872A1/en not_active Abandoned
- 2005-02-15 CA CA002554310A patent/CA2554310A1/en not_active Abandoned
- 2005-02-15 EP EP08158356A patent/EP2048137A1/en not_active Withdrawn
- 2005-02-15 DE DE602005013491T patent/DE602005013491D1/de active Active
- 2005-02-15 WO PCT/GB2005/000545 patent/WO2005080359A1/en active Application Filing
- 2005-02-15 AT AT05708360T patent/ATE426597T1/de not_active IP Right Cessation
- 2005-02-15 RU RU2006130684/04A patent/RU2392275C2/ru not_active IP Right Cessation
- 2005-02-15 JP JP2006553652A patent/JP2007523142A/ja active Pending
- 2005-02-15 AU AU2005214132A patent/AU2005214132B9/en not_active Ceased
- 2005-02-15 ES ES05708360T patent/ES2322709T3/es active Active
- 2005-02-15 BR BRPI0507746-0A patent/BRPI0507746A/pt not_active IP Right Cessation
- 2005-02-15 KR KR1020067019123A patent/KR20070007103A/ko not_active Application Discontinuation
- 2005-02-15 EP EP05708360A patent/EP1718624B1/en active Active
- 2005-02-16 AR ARP050100540A patent/AR047678A1/es not_active Application Discontinuation
- 2005-02-17 UY UY28756A patent/UY28756A1/es unknown
- 2005-02-17 TW TW094104677A patent/TW200602028A/zh unknown
-
2006
- 2006-07-26 NO NO20063452A patent/NO20063452L/no not_active Application Discontinuation
- 2006-08-01 IL IL177216A patent/IL177216A0/en unknown
-
2007
- 2007-03-26 HK HK07103207.6A patent/HK1096092A1/xx not_active IP Right Cessation
-
2010
- 2010-03-12 US US12/722,936 patent/US20110034432A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1718624A1 (en) | 2006-11-08 |
RU2006130684A (ru) | 2008-03-27 |
HK1096092A1 (en) | 2007-05-25 |
ES2322709T3 (es) | 2009-06-25 |
AU2005214132B2 (en) | 2009-05-07 |
AR047678A1 (es) | 2006-02-01 |
CA2554310A1 (en) | 2005-09-01 |
IL177216A0 (en) | 2006-12-10 |
TW200602028A (en) | 2006-01-16 |
US20080280872A1 (en) | 2008-11-13 |
DE602005013491D1 (de) | 2009-05-07 |
EP2048137A1 (en) | 2009-04-15 |
WO2005080359A1 (en) | 2005-09-01 |
KR20070007103A (ko) | 2007-01-12 |
RU2392275C2 (ru) | 2010-06-20 |
AU2005214132B9 (en) | 2009-06-25 |
ATE426597T1 (de) | 2009-04-15 |
UY28756A1 (es) | 2005-09-30 |
AU2005214132A1 (en) | 2005-09-01 |
JP2007523142A (ja) | 2007-08-16 |
US20110034432A1 (en) | 2011-02-10 |
BRPI0507746A (pt) | 2007-07-10 |
EP1718624B1 (en) | 2009-03-25 |
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