NO20062256L - Hydroksyalkylsubstituerte pyrido-7-pyrimidin-7-oner - Google Patents

Hydroksyalkylsubstituerte pyrido-7-pyrimidin-7-oner

Info

Publication number
NO20062256L
NO20062256L NO20062256A NO20062256A NO20062256L NO 20062256 L NO20062256 L NO 20062256L NO 20062256 A NO20062256 A NO 20062256A NO 20062256 A NO20062256 A NO 20062256A NO 20062256 L NO20062256 L NO 20062256L
Authority
NO
Norway
Prior art keywords
pyrimidin
hydroxyalkyl
ones
substituted pyrido
formula
Prior art date
Application number
NO20062256A
Other languages
English (en)
Norwegian (no)
Inventor
David Michael Goldstein
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20062256L publication Critical patent/NO20062256L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20062256A 2003-11-13 2006-05-19 Hydroksyalkylsubstituerte pyrido-7-pyrimidin-7-oner NO20062256L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51978903P 2003-11-13 2003-11-13
PCT/EP2004/012475 WO2005047284A1 (en) 2003-11-13 2004-11-04 Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones

Publications (1)

Publication Number Publication Date
NO20062256L true NO20062256L (no) 2006-06-06

Family

ID=34590444

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062256A NO20062256L (no) 2003-11-13 2006-05-19 Hydroksyalkylsubstituerte pyrido-7-pyrimidin-7-oner

Country Status (27)

Country Link
US (2) US7348331B2 (hr)
EP (1) EP1685131B1 (hr)
JP (1) JP4616839B2 (hr)
KR (1) KR100816321B1 (hr)
CN (1) CN100455582C (hr)
AR (1) AR046705A1 (hr)
AT (1) ATE356124T1 (hr)
AU (1) AU2004289428B2 (hr)
BR (1) BRPI0416030A (hr)
CA (1) CA2544247A1 (hr)
CO (1) CO5690600A2 (hr)
DE (1) DE602004005238T2 (hr)
DK (1) DK1685131T3 (hr)
ES (1) ES2281843T3 (hr)
HK (1) HK1099021A1 (hr)
HR (1) HRP20070132T3 (hr)
IL (1) IL175284A0 (hr)
MY (1) MY141011A (hr)
NO (1) NO20062256L (hr)
NZ (1) NZ546634A (hr)
PL (1) PL1685131T3 (hr)
PT (1) PT1685131E (hr)
RU (1) RU2348632C2 (hr)
SI (1) SI1685131T1 (hr)
TW (1) TWI349670B (hr)
WO (1) WO2005047284A1 (hr)
ZA (1) ZA200603829B (hr)

Families Citing this family (19)

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AU2007275696B2 (en) * 2006-07-17 2011-11-10 Amgen Inc. Quinazoline and pyridopyrimidine derivatives as p38 kinase inhibitors
CA2672848A1 (en) * 2006-12-22 2008-07-03 F. Hoffmann-La Roche Ag Compounds and methods for amino-alkylenediol synthesis
JP2010529973A (ja) * 2007-06-15 2010-09-02 エフ.ホフマン−ラ ロシュ アーゲー 3−アミノ−ペンタン−1,5−ジオールの新規製造方法
US8889696B2 (en) * 2009-12-18 2014-11-18 Temple University—Of the Commonwealth System of Higher Education Substituted pyrido[2,3-d]pyrimidin-7(8H)-ones and therapeutic uses thereof
PL3102577T3 (pl) * 2014-02-07 2019-03-29 Principia Biopharma Inc. Pochodne chinolonowe jako inhibitory receptora czynnika wzrostu fibroblastów
CN118666836A (zh) 2015-08-11 2024-09-20 普林斯匹亚生物制药公司 用于制备fgfr抑制剂的方法
CN105418609B (zh) * 2015-12-31 2017-06-23 山东大学 4‑(1,2,3‑三氮唑取代苯胺基)‑吡啶骈嘧啶酮衍生物及其制备方法与应用
WO2017151409A1 (en) 2016-02-29 2017-09-08 University Of Florida Research Foundation, Incorporated Chemotherapeutic methods
KR20220119529A (ko) 2016-06-02 2022-08-29 애브비 인코포레이티드 글루코코르티코이드 수용체 작용제 및 이의 면역접합체
AU2017277478B2 (en) 2016-06-08 2023-03-16 Support-Venture Gmbh Pharmaceutical combinations for treating cancer
SG11201900776TA (en) 2016-08-17 2019-03-28 Support Venture Gmbh Method of preventing or treating hearing loss
EA201992004A1 (ru) * 2017-04-04 2020-02-20 Кинарус Аг Способы предотвращения или лечения офтальмологических заболеваний
WO2019071144A1 (en) 2017-10-05 2019-04-11 Fulcrum Therapeutics, Inc. USE OF P38 INHIBITORS TO REDUCE DUX4 EXPRESSION
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
AU2018374634A1 (en) 2017-12-01 2020-05-28 Abbvie Inc. Glucocorticoid receptor agonist and immunoconjugates thereof
ES2929406T3 (es) 2018-05-21 2022-11-29 Nerviano Medical Sciences Srl Compuestos de piridonas heterocondensadas y su uso como inhibidores de IDH
CN112512586A (zh) 2018-07-13 2021-03-16 基纳鲁斯股份公司 用于预防或治疗纤维化疾病的ppar激动剂和p38激酶抑制剂的组合
CN115038700A (zh) 2019-11-08 2022-09-09 内尔维亚诺医疗科学公司 偕二取代的杂环化合物及其作为idh抑制剂的用途
WO2022034031A1 (en) 2020-08-11 2022-02-17 Kinarus Ag Methods of preventing or treating covid-19 and related viral diseases or disorders

Family Cites Families (19)

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Publication number Priority date Publication date Assignee Title
US4215216A (en) * 1979-04-18 1980-07-29 American Home Products Corporation 7,8-Dihydro-2,5,8-trisubstituted-7-oxo-pyrido[2,3-d]pyrimidine-6-carboxylic acid derivatives
US5037826A (en) * 1986-10-15 1991-08-06 Schering Corporation 1-substituted naphthyridine and pyridopyrazine derivatives
AU598093B2 (en) 1987-02-07 1990-06-14 Wellcome Foundation Limited, The Pyridopyrimidines, methods for their preparation and pharmaceutical formulations thereof
WO1993017682A1 (en) 1992-03-04 1993-09-16 Abbott Laboratories Angiotensin ii receptor antagonists
AU711426B2 (en) 1994-11-14 1999-10-14 Warner-Lambert Company 6-aryl pyrido(2,3-d)pyrimidines and naphthyridines for inhibiting protein tyrosine kinase mediated cellular proliferation
IL115256A0 (en) * 1994-11-14 1995-12-31 Warner Lambert Co 6-Aryl pyrido (2,3-d) pyrimidines and naphthyridines and their use
IL117923A (en) 1995-05-03 2000-06-01 Warner Lambert Co Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds
US5620981A (en) * 1995-05-03 1997-04-15 Warner-Lambert Company Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation
EP0964864B1 (en) 1997-02-05 2008-04-09 Warner-Lambert Company LLC Pyrido 2,3-d pyrimidines and 4-aminopyrimidines as inhibitors of cellular proliferation
US5945422A (en) * 1997-02-05 1999-08-31 Warner-Lambert Company N-oxides of amino containing pyrido 2,3-D! pyrimidines
ES2310039T3 (es) 1998-05-26 2008-12-16 Warner-Lambert Company Llc Pirimidinas biciclicas y 3,4-dihidropirimidinas biciclicas como inhibidores de la proliferacion celular.
US7053070B2 (en) * 2000-01-25 2006-05-30 Warner-Lambert Company Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors
US20040224958A1 (en) 2000-01-27 2004-11-11 Booth Richard John Pyridopyrimidinone derivatives for treatment of neurodegenerative disease
MXPA02008535A (es) 2000-03-06 2002-12-13 Warner Lambert Co Inhibidores de 5-alquilpirido (2.3-d) pirimidinas tirosina quinasa.
CN1275964C (zh) * 2000-08-31 2006-09-20 霍夫曼-拉罗奇有限公司 作为细胞增殖抑制剂的7-氧代吡啶并嘧啶
US6518276B2 (en) * 2000-08-31 2003-02-11 Syntex (U.S.A.) Llc 7-oxo-pyridopyrimidines (II)
KR100639772B1 (ko) * 2001-02-12 2006-10-30 에프. 호프만-라 로슈 아게 6-치환된 피리도-피리미딘
GEP20063909B (en) * 2002-01-22 2006-08-25 Warner Lambert Co 2-(PYRIDIN-2-YLAMINO)-PYRIDO[2,3d] PYRIMIDIN-7-ONES
FR2897336B1 (fr) 2006-02-10 2010-07-30 Ranger France Support d'aile pour vehicule automobile

Also Published As

Publication number Publication date
HK1099021A1 (en) 2007-08-03
HRP20070132T3 (hr) 2007-05-31
AR046705A1 (es) 2005-12-21
ZA200603829B (en) 2007-10-31
US20080119497A1 (en) 2008-05-22
ATE356124T1 (de) 2007-03-15
MY141011A (en) 2010-02-25
RU2006120486A (ru) 2008-01-20
EP1685131A1 (en) 2006-08-02
DK1685131T3 (da) 2007-07-09
PT1685131E (pt) 2007-05-31
DE602004005238D1 (de) 2007-04-19
EP1685131B1 (en) 2007-03-07
CO5690600A2 (es) 2006-10-31
ES2281843T3 (es) 2007-10-01
DE602004005238T2 (de) 2007-11-08
BRPI0416030A (pt) 2007-01-02
KR20060086417A (ko) 2006-07-31
US7348331B2 (en) 2008-03-25
NZ546634A (en) 2010-01-29
SI1685131T1 (sl) 2007-06-30
CN1882585A (zh) 2006-12-20
RU2348632C2 (ru) 2009-03-10
JP4616839B2 (ja) 2011-01-19
TWI349670B (en) 2011-10-01
CA2544247A1 (en) 2005-05-26
AU2004289428A1 (en) 2005-05-26
US7750016B2 (en) 2010-07-06
US20050107408A1 (en) 2005-05-19
CN100455582C (zh) 2009-01-28
TW200526657A (en) 2005-08-16
PL1685131T3 (pl) 2007-08-31
KR100816321B1 (ko) 2008-03-24
JP2007510686A (ja) 2007-04-26
IL175284A0 (en) 2006-09-05
WO2005047284A1 (en) 2005-05-26
AU2004289428B2 (en) 2010-06-03

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