NO20061974L - Salter og polymorfer av en potent antidiabetisk forbindelse - Google Patents

Salter og polymorfer av en potent antidiabetisk forbindelse

Info

Publication number
NO20061974L
NO20061974L NO20061974A NO20061974A NO20061974L NO 20061974 L NO20061974 L NO 20061974L NO 20061974 A NO20061974 A NO 20061974A NO 20061974 A NO20061974 A NO 20061974A NO 20061974 L NO20061974 L NO 20061974L
Authority
NO
Norway
Prior art keywords
polymorphs
salts
compound
antidiabetic compound
treatment
Prior art date
Application number
NO20061974A
Other languages
English (en)
Other versions
NO333002B1 (no
Inventor
Lawrence Ray Mcgee
Henry T Kruk
Bing Yang
Original Assignee
Amgen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen filed Critical Amgen
Publication of NO20061974L publication Critical patent/NO20061974L/no
Publication of NO333002B1 publication Critical patent/NO333002B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Salter og polymorfe former av en forbindelse som er anvendbar ved behandling av betennelsestilstander og metabolske tilstander og sykdommer tilveiebringes heri. Nærmere bestemt tilveiebringer oppfinnelsen salter og polymorfe former av en forbindelse som modulerer ekspresjon og/eller funksjon av en peroksison proliferator-aktivert receptor. Saltene og de polymorfe formene er anvendbare for behandling eller forebyggelse av tilstander og forstyrrelser forbundet med energihomeostase, for eksempel type II diabetes, lipidmetabolisme, adipocyttdifferensiering og betennelse.
NO20061974A 2003-10-03 2006-05-03 Benzensulfonatsalt og polymorfe former og fremgangsmate for fremstilling samt farmasoytisk preparat derav NO333002B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50847003P 2003-10-03 2003-10-03
PCT/US2004/032552 WO2005033074A2 (en) 2003-10-03 2004-10-04 Salts and polymorphs of a potent antidiabetic compound

Publications (2)

Publication Number Publication Date
NO20061974L true NO20061974L (no) 2006-07-03
NO333002B1 NO333002B1 (no) 2013-02-11

Family

ID=34421741

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20061974A NO333002B1 (no) 2003-10-03 2006-05-03 Benzensulfonatsalt og polymorfe former og fremgangsmate for fremstilling samt farmasoytisk preparat derav

Country Status (19)

Country Link
US (2) US7223761B2 (no)
EP (1) EP1677797B1 (no)
JP (2) JP5426813B2 (no)
KR (1) KR101156277B1 (no)
CN (1) CN1886134A (no)
AT (1) ATE546142T1 (no)
AU (1) AU2004278416B2 (no)
BR (1) BRPI0414957A (no)
CA (1) CA2540536C (no)
DK (1) DK1677797T3 (no)
EA (1) EA013367B1 (no)
ES (1) ES2386670T3 (no)
IL (1) IL174728A (no)
IS (1) IS8378A (no)
MX (1) MXPA06003313A (no)
NO (1) NO333002B1 (no)
NZ (1) NZ546783A (no)
WO (1) WO2005033074A2 (no)
ZA (1) ZA200602669B (no)

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JP2012097090A (ja) 2012-05-24
BRPI0414957A (pt) 2006-11-07
IL174728A0 (en) 2006-08-20
US20050143416A1 (en) 2005-06-30
EA013367B1 (ru) 2010-04-30
NZ546783A (en) 2008-11-28
KR101156277B1 (ko) 2012-07-05
US7223761B2 (en) 2007-05-29
WO2005033074A2 (en) 2005-04-14
US20070293536A1 (en) 2007-12-20
EP1677797A4 (en) 2009-03-25
EP1677797A2 (en) 2006-07-12
CA2540536C (en) 2013-07-02
AU2004278416A1 (en) 2005-04-14
CN1886134A (zh) 2006-12-27
ES2386670T3 (es) 2012-08-24
KR20060097121A (ko) 2006-09-13
ZA200602669B (en) 2007-07-25
EP1677797B1 (en) 2012-02-22
AU2004278416B2 (en) 2010-04-15
US8003665B2 (en) 2011-08-23
JP5426813B2 (ja) 2014-02-26
WO2005033074A3 (en) 2005-06-16
IS8378A (is) 2006-03-27
CA2540536A1 (en) 2005-04-14
DK1677797T3 (da) 2012-06-04
NO333002B1 (no) 2013-02-11
JP2007507537A (ja) 2007-03-29
EA200600701A1 (ru) 2006-10-27
IL174728A (en) 2011-06-30
MXPA06003313A (es) 2006-06-08
ATE546142T1 (de) 2012-03-15

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