NO20060985L - Inhibitorer av Akt aktivitet - Google Patents
Inhibitorer av Akt aktivitetInfo
- Publication number
- NO20060985L NO20060985L NO20060985A NO20060985A NO20060985L NO 20060985 L NO20060985 L NO 20060985L NO 20060985 A NO20060985 A NO 20060985A NO 20060985 A NO20060985 A NO 20060985A NO 20060985 L NO20060985 L NO 20060985L
- Authority
- NO
- Norway
- Prior art keywords
- inhibitors
- akt activity
- activity
- compounds
- akt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Oppfinnelsen angår nye lH-imidazo[4,5-c]pyridin-2-yl-forbindelser, anvendelsen av slike forbindelser som inhibitorer av proteinkinase B-aktivitet og i behandlingen av cancer og artritt.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49085103P | 2003-07-29 | 2003-07-29 | |
US49105503P | 2003-07-30 | 2003-07-30 | |
US49310103P | 2003-08-06 | 2003-08-06 | |
US49475203P | 2003-08-13 | 2003-08-13 | |
US50701403P | 2003-09-29 | 2003-09-29 | |
US53084703P | 2003-12-18 | 2003-12-18 | |
PCT/US2004/024340 WO2005011700A1 (en) | 2003-07-29 | 2004-07-28 | INHIBITORS OF Akt ACTIVITY |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20060985L true NO20060985L (no) | 2006-04-19 |
Family
ID=34120170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20060985A NO20060985L (no) | 2003-07-29 | 2006-02-28 | Inhibitorer av Akt aktivitet |
Country Status (16)
Country | Link |
---|---|
US (1) | US20080255143A1 (no) |
EP (1) | EP1653961A4 (no) |
JP (1) | JP2007500709A (no) |
KR (1) | KR20060066714A (no) |
AR (1) | AR045134A1 (no) |
AU (1) | AU2004261214A1 (no) |
BR (1) | BRPI0412993A (no) |
CA (1) | CA2534038A1 (no) |
CO (1) | CO5640140A2 (no) |
IL (1) | IL173174A0 (no) |
IS (1) | IS8322A (no) |
MA (1) | MA27933A1 (no) |
MX (1) | MXPA06001134A (no) |
NO (1) | NO20060985L (no) |
TW (1) | TW200523262A (no) |
WO (1) | WO2005011700A1 (no) |
Families Citing this family (89)
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ATE556713T1 (de) | 1999-01-13 | 2012-05-15 | Bayer Healthcare Llc | Omega-carboxyarylsubstituierte-diphenyl- harnstoffe als p38-kinasehemmer |
US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
AU2003209116A1 (en) | 2002-02-11 | 2003-09-04 | Bayer Pharmaceuticals Corporation | Aryl ureas with angiogenesis inhibiting activity |
US7557129B2 (en) | 2003-02-28 | 2009-07-07 | Bayer Healthcare Llc | Cyanopyridine derivatives useful in the treatment of cancer and other disorders |
JP4860474B2 (ja) | 2003-05-20 | 2012-01-25 | バイエル、ファーマシューテイカルズ、コーポレイション | Pdgfrによって仲介される病気のためのジアリール尿素 |
DK1663978T3 (da) | 2003-07-23 | 2008-04-07 | Bayer Pharmaceuticals Corp | Fluorsubstitueret omega-carboxyaryl-diphenylurinstof til behandling og forebyggelse af sygdomme og lidelser |
US20070123561A1 (en) * | 2003-10-06 | 2007-05-31 | Dennis Lee | Preparation of 1,7-disubstituted azabensimidazoles as kinase inhibitors |
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AU2006343359A1 (en) | 2005-06-03 | 2007-11-15 | Xenon Pharmaceuticals Inc. | Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors |
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US20080063637A1 (en) * | 2006-05-19 | 2008-03-13 | The Trustees Of Tufts College | Regulation of oncogenesis by Akt-specific isoforms |
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EP2286232B1 (en) * | 2008-05-16 | 2012-02-29 | Cellzome Ag | Methods for the identification of parp interacting molecules and for purification of parp proteins |
MX2012007367A (es) | 2009-12-30 | 2013-04-03 | Arqule Inc | Compuestos substituidos de imidazopiridinilo-aminopiridina. |
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KR101419999B1 (ko) * | 2011-03-31 | 2014-08-12 | 건국대학교 산학협력단 | Akt 음성 조절제로서의 Hades의 용도 |
CN103635192B (zh) | 2011-04-01 | 2017-07-04 | 基因泰克公司 | Akt抑制剂化合物和化疗剂的组合以及使用方法 |
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AR095604A1 (es) | 2013-03-15 | 2015-10-28 | Syngenta Participations Ag | Derivados de imidazopiridina útiles como microbicidas |
DK3102555T3 (da) * | 2014-02-05 | 2021-08-09 | VM Oncology LLC | Sammensætninger af forbindelser og anvendelser deraf |
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JP2023530351A (ja) | 2020-06-18 | 2023-07-14 | レヴォリューション・メディスンズ,インコーポレイテッド | Ras阻害剤への獲得耐性を遅延させる、防止する、及び、治療する方法 |
WO2022014640A1 (ja) | 2020-07-15 | 2022-01-20 | 大鵬薬品工業株式会社 | 腫瘍の治療に使用されるピリミジン化合物を含む組み合わせ |
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-
2004
- 2004-07-27 TW TW093122340A patent/TW200523262A/zh unknown
- 2004-07-27 AR ARP040102668A patent/AR045134A1/es not_active Application Discontinuation
- 2004-07-28 BR BRPI0412993-8A patent/BRPI0412993A/pt not_active IP Right Cessation
- 2004-07-28 CA CA002534038A patent/CA2534038A1/en not_active Abandoned
- 2004-07-28 KR KR1020067002022A patent/KR20060066714A/ko not_active Application Discontinuation
- 2004-07-28 US US10/565,329 patent/US20080255143A1/en not_active Abandoned
- 2004-07-28 JP JP2006522030A patent/JP2007500709A/ja active Pending
- 2004-07-28 EP EP04779406A patent/EP1653961A4/en not_active Withdrawn
- 2004-07-28 WO PCT/US2004/024340 patent/WO2005011700A1/en active Application Filing
- 2004-07-28 MX MXPA06001134A patent/MXPA06001134A/es unknown
- 2004-07-28 AU AU2004261214A patent/AU2004261214A1/en not_active Abandoned
-
2006
- 2006-01-16 IL IL173174A patent/IL173174A0/en unknown
- 2006-01-26 CO CO06007246A patent/CO5640140A2/es not_active Application Discontinuation
- 2006-01-27 MA MA28757A patent/MA27933A1/fr unknown
- 2006-02-22 IS IS8322A patent/IS8322A/is unknown
- 2006-02-28 NO NO20060985A patent/NO20060985L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2534038A1 (en) | 2005-02-10 |
AU2004261214A1 (en) | 2005-02-10 |
BRPI0412993A (pt) | 2006-10-03 |
CO5640140A2 (es) | 2006-05-31 |
EP1653961A1 (en) | 2006-05-10 |
KR20060066714A (ko) | 2006-06-16 |
JP2007500709A (ja) | 2007-01-18 |
IS8322A (is) | 2006-02-22 |
MXPA06001134A (es) | 2006-04-11 |
AR045134A1 (es) | 2005-10-19 |
WO2005011700A1 (en) | 2005-02-10 |
MA27933A1 (fr) | 2006-06-01 |
IL173174A0 (en) | 2006-06-11 |
US20080255143A1 (en) | 2008-10-16 |
TW200523262A (en) | 2005-07-16 |
EP1653961A4 (en) | 2009-04-01 |
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