NO20060774L - Kinolin- og kinazolinderivater som har affinitet for 5HT1-typereseptorer - Google Patents
Kinolin- og kinazolinderivater som har affinitet for 5HT1-typereseptorerInfo
- Publication number
- NO20060774L NO20060774L NO20060774A NO20060774A NO20060774L NO 20060774 L NO20060774 L NO 20060774L NO 20060774 A NO20060774 A NO 20060774A NO 20060774 A NO20060774 A NO 20060774A NO 20060774 L NO20060774 L NO 20060774L
- Authority
- NO
- Norway
- Prior art keywords
- quinoline
- affinity
- quinazoline derivatives
- type receptors
- receptors
- Prior art date
Links
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 title 2
- 125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 title 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
- C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
- C04B35/632—Organic additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Manufacturing & Machinery (AREA)
- Ceramic Engineering (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Inorganic Chemistry (AREA)
- Psychiatry (AREA)
- Materials Engineering (AREA)
- Structural Engineering (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0316915.8A GB0316915D0 (en) | 2003-07-18 | 2003-07-18 | Compounds |
| PCT/EP2004/008000 WO2005014552A1 (en) | 2003-07-18 | 2004-07-15 | Quinoline and quinazoline derivatives having affinity for 5ht1-type receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20060774L true NO20060774L (no) | 2006-04-06 |
Family
ID=27764115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20060774A NO20060774L (no) | 2003-07-18 | 2006-02-17 | Kinolin- og kinazolinderivater som har affinitet for 5HT1-typereseptorer |
Country Status (28)
| Country | Link |
|---|---|
| US (5) | US7279481B2 (is) |
| EP (3) | EP2145622A1 (is) |
| JP (1) | JP2006528146A (is) |
| KR (1) | KR20060041242A (is) |
| CN (1) | CN100441571C (is) |
| AR (1) | AR046394A1 (is) |
| AT (2) | ATE448205T1 (is) |
| AU (1) | AU2004263268B2 (is) |
| BR (1) | BRPI0412695A (is) |
| CA (1) | CA2532452A1 (is) |
| CY (1) | CY1107974T1 (is) |
| DE (2) | DE602004012564T2 (is) |
| DK (1) | DK1646613T3 (is) |
| ES (2) | ES2302543T3 (is) |
| GB (1) | GB0316915D0 (is) |
| HR (1) | HRP20080226T3 (is) |
| IL (1) | IL173036A0 (is) |
| IS (1) | IS2744B (is) |
| MA (1) | MA27926A1 (is) |
| MX (1) | MXPA06000716A (is) |
| NO (1) | NO20060774L (is) |
| NZ (1) | NZ544586A (is) |
| PL (1) | PL1646613T3 (is) |
| PT (1) | PT1646613E (is) |
| RU (1) | RU2402533C2 (is) |
| SI (1) | SI1646613T1 (is) |
| TW (1) | TW200521115A (is) |
| WO (1) | WO2005014552A1 (is) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7504395B2 (en) | 2001-07-20 | 2009-03-17 | Psychogenics, Inc. | Treatment for attention-deficit hyperactivity disorder |
| GB0316915D0 (en) | 2003-07-18 | 2003-08-20 | Glaxo Group Ltd | Compounds |
| BRPI0512193B8 (pt) * | 2004-06-17 | 2021-05-25 | Cytokinetics Inc | composto ou sal farmaceuticamente aceitável, composição farmacêutica, e, uso do composto ou sal |
| KR100817538B1 (ko) * | 2006-07-05 | 2008-03-27 | 한국화학연구원 | 신규 치환된―１ｈ―퀴나졸린―２,４―디온 유도체, 이의제조방법 및 이를 함유하는 약학적 조성물 |
| JP2010513569A (ja) * | 2006-12-19 | 2010-04-30 | ユニバーシティ オブ バージニア パテント ファウンデーション | アルコール摂取に対するトピラメートおよびオンダンセトロンの併用効果 |
| US20100076006A1 (en) * | 2007-01-31 | 2010-03-25 | University Of Virginia Patent Foundation | Topiramate Plus Naltrexone for the Treatment of Addictive Disorders |
| EP2016943B1 (en) | 2007-07-19 | 2011-02-23 | Laboratorios del Dr. Esteve S.A. | Substituted tetrahydro-quinoline-sulfonamide compounds, their preparation and use as medicaments |
| WO2009029308A1 (en) * | 2007-08-27 | 2009-03-05 | University Of Virginia Patent Foundation | Medication combinations for the treatment of alcoholism and drug addiction |
| ES2430940T3 (es) * | 2008-02-28 | 2013-11-22 | University Of Virginia Patent Foundation | Gen del transportador de serotonina y tratamiento del alcoholismo |
| CA2722326A1 (en) | 2008-04-24 | 2009-10-29 | Incyte Corporation | Macrocyclic compounds and their use as kinase inhibitors |
| EP2298199B1 (en) * | 2008-05-06 | 2012-05-23 | Biedermann Technologies GmbH & Co. KG | Rod-shaped implant, in particular for the dynamic stabilization of the spine |
| US20100298397A1 (en) * | 2009-05-19 | 2010-11-25 | Singh Nikhilesh N | Method of treatment of obsessive compulsive disorder with ondansetron |
| CN101671336B (zh) | 2009-09-23 | 2013-11-13 | 辽宁利锋科技开发有限公司 | 芳杂环并嘧啶衍生物和类似物及其制备方法和用途 |
| EP2308850A1 (en) * | 2009-10-06 | 2011-04-13 | Laboratorios Del. Dr. Esteve, S.A. | Heterocycyl-substituted-alkylamino phenyl derivatives, their preparation and use as medicaments |
| HUE035574T2 (en) | 2010-07-02 | 2018-05-28 | Univ Virginia Patent Foundation | Molecular genetic approach to treatment and diagnosis of alcohol and drug dependence |
| UA114406C2 (uk) * | 2011-08-09 | 2017-06-12 | Такеда Фармасьютікал Компані Лімітед | Похідні циклопропанаміну як інгібітори lsd1 |
| US20130096173A1 (en) | 2011-09-09 | 2013-04-18 | Bankole A. Johnson | Molecular genetic approach to treatment and diagnosis of alcohol and drug dependence |
| GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
| CA2872883A1 (en) * | 2012-05-09 | 2013-11-14 | Sunovion Pharmaceuticals Inc. | Heteroaryl compounds and methods of use thereof |
| CN103508927A (zh) * | 2012-06-25 | 2014-01-15 | 天津药物研究院 | 一种2-甲磺酰氨基二苯醚的制备方法 |
| US9751885B2 (en) | 2012-10-12 | 2017-09-05 | Takeda Pharmaceutical Company Limited | Cyclopropanamine compound and use thereof |
| GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
| CA2927527C (en) | 2013-11-20 | 2021-06-01 | Sanwa Kagaku Kenkyusho Co., Ltd. | Novel 3-azabicyclo[3.1.0]hexane derivative and use thereof as u-opioid receptor antagonist |
| SG11201608340UA (en) | 2014-04-11 | 2016-11-29 | Takeda Pharmaceuticals Co | Cyclopropanamine compound and use thereof |
| WO2016075314A1 (fr) | 2014-11-13 | 2016-05-19 | Institut National De La Recherche Agronomique | Identification de facteurs de transcription de yarrowia lipolytica affectant la production de proteines |
| FR3028527A1 (fr) | 2014-11-13 | 2016-05-20 | Pivert | Identification de facteurs de transcription de yarrowia lipolytica |
| PL3065748T3 (pl) | 2014-12-23 | 2018-07-31 | 4D Pharma Research Limited | Szczep Bacteroides thetaiotaomicron i jego zastosowanie w zmniejszaniu zapalenia |
| KR20170091157A (ko) | 2014-12-23 | 2017-08-08 | 4디 파마 리서치 리미티드 | 피린 폴리펩티드 및 면역 조정 |
| MD3650033T2 (ro) | 2015-06-15 | 2022-08-31 | 4D Pharma Res Ltd | Compoziții conţinând tulpini bacteriene |
| MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| EA201890050A1 (ru) | 2015-06-15 | 2018-06-29 | 4Д Фарма Рисёрч Лимитед | Композиции, содержащие бактериальные штаммы |
| SI3240554T1 (sl) | 2015-06-15 | 2019-12-31 | 4D Pharma Research Limited, | Blautia stercosis in wexlerae za uporabo v zdravljenju vnetnih in avtoimunskih bolezni |
| AU2016357554B2 (en) | 2015-11-20 | 2019-04-04 | Cj Bioscience, Inc. | Compositions comprising bacterial strains |
| GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| EP3520801A1 (en) | 2016-03-04 | 2019-08-07 | 4D Pharma Plc | Compositions comprising bacterial blautia strains for treating visceral hypersensitivity |
| GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
| TW201821093A (zh) | 2016-07-13 | 2018-06-16 | 英商４Ｄ製藥有限公司 | 包含細菌菌株之組合物 |
| GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
| JP7212945B2 (ja) | 2017-05-22 | 2023-01-26 | フォーディー ファーマ リサーチ リミテッド | 細菌株を含む組成物 |
| TW201907931A (zh) | 2017-05-24 | 2019-03-01 | 英商4D製藥研究有限公司 | 包含細菌菌株之組合物 |
| CN115813955A (zh) | 2017-06-14 | 2023-03-21 | 4D制药研究有限公司 | 包含细菌菌株的组合物 |
| WO2018229188A1 (en) | 2017-06-14 | 2018-12-20 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| MD3804737T2 (ro) | 2017-06-14 | 2022-10-31 | 4D Pharma Res Limited | Compoziții care conțin tulpini bacteriene |
| CN108047143A (zh) * | 2017-12-18 | 2018-05-18 | 刘凤娟 | 一种用于治疗功能性胃肠病的5-羟色胺受体拮抗剂的合成方法 |
| RS64641B1 (sr) | 2018-06-27 | 2023-10-31 | Bristol Myers Squibb Co | Supstituisana jedinjenja naftiridinona korisna kao aktivatori t ćelija |
| US11866430B2 (en) | 2018-06-27 | 2024-01-09 | Bristol-Myers Squibb Company | Naphthyridinone compounds useful as T cell activators |
| AR119821A1 (es) | 2019-08-28 | 2022-01-12 | Bristol Myers Squibb Co | Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t |
| WO2021133751A1 (en) | 2019-12-23 | 2021-07-01 | Bristol-Myers Squibb Company | Substituted quinazolinyl compounds useful as t cell activators |
| MX2022007130A (es) | 2019-12-23 | 2022-07-11 | Bristol Myers Squibb Co | Derivados de piperazina sustituidos utiles como activadores de celulas t. |
| AR120823A1 (es) | 2019-12-23 | 2022-03-23 | Bristol Myers Squibb Co | Compuestos bicíclicos sustituidos útiles como activadores de células t |
| CN118308475B (zh) * | 2024-03-18 | 2024-11-26 | 安徽医科大学第一附属医院 | Htr1b作为胚胎发育停滞的诊断标志物和治疗靶点方面的应用 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2641602A (en) | 1950-11-29 | 1953-06-09 | Eastman Kodak Co | 1, 8-dihydroxy-5-nitro-4-hydroxyethylphenyl aminoanthraquinone compounds |
| US3937708A (en) | 1971-06-07 | 1976-02-10 | Boehringer Ingelheim Gmbh | N-phenyl-imidazolidine-1-ones |
| US3992537A (en) | 1971-06-07 | 1976-11-16 | Boehringer Ingelheim Gmbh | Pharmaceutical compositions containing an N-phenyl-imidazolidine-2-one and method of use |
| US3975525A (en) | 1971-06-07 | 1976-08-17 | Boehringer Ingelheim Gmbh | N-[4'-Imidazolidinon-(2)-yl-phenethyl]-N'-pyridyl-piperazines and salts thereof |
| JPS5883677A (ja) | 1981-11-11 | 1983-05-19 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
| US4891275A (en) * | 1982-10-29 | 1990-01-02 | Norsk Hydro A.S. | Aluminum shapes coated with brazing material and process of coating |
| JPS6354363A (ja) | 1986-08-26 | 1988-03-08 | Ss Pharmaceut Co Ltd | キノリン誘導体 |
| FI95572C (fi) | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| US4933447A (en) | 1987-09-24 | 1990-06-12 | Ss Pharmaceutical Co., Ltd. | Quinoline derivatives |
| US4891375A (en) | 1988-01-13 | 1990-01-02 | Pfizer Inc. | Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds |
| JP2777159B2 (ja) | 1988-12-22 | 1998-07-16 | エーザイ株式会社 | 環状アミン誘導体を含有する医薬 |
| IL101722A (en) * | 1991-05-02 | 1996-05-14 | Wyeth John & Brother Ltd | Piperazine derivatives their preparation and pharmaceutical compositions containing them |
| NZ240863A (en) * | 1991-09-11 | 1995-04-27 | Mcneilab Inc | Substituted 4-aryl piperidine and 4-aryl piperazine derivatives, preparation and pharmaceutical compositions thereof |
| GB9300194D0 (en) | 1993-01-06 | 1993-03-03 | Wyeth John & Brother Ltd | Piperazine derivatives |
| GB9300195D0 (en) | 1993-01-06 | 1993-03-03 | Wyeth John & Brother Ltd | Piperazine derivatives |
| GB9308725D0 (en) | 1993-04-27 | 1993-06-09 | Wyeth John & Brother Ltd | Piperazine derivatives |
| AU708053B2 (en) * | 1996-03-29 | 1999-07-29 | Duphar International Research B.V. | Piperazine and piperidine compounds |
| AU2446297A (en) | 1996-04-30 | 1997-11-19 | Warner-Lambert Company | Substituted piperazines and piperidines as central nervous system agents |
| GB2312843A (en) | 1996-05-07 | 1997-11-12 | Merck & Co Inc | Method of treating rheumatoid arthritis |
| WO1998025617A1 (en) | 1996-12-13 | 1998-06-18 | Merck & Co., Inc. | Substituted aryl piperazines as modulators of chemokine receptor activity |
| EP0900792B1 (en) | 1997-09-02 | 2003-10-29 | Duphar International Research B.V | Piperazine and piperidine derivatives as 5-HT1A and dopamine D2-receptor (ant)agonists |
| ATE253058T1 (de) | 1997-09-02 | 2003-11-15 | Duphar Int Res | Piperidin- und piperazin derivate als 5-ht1- rezeptor-agonisten |
| AU744539B2 (en) | 1997-10-27 | 2002-02-28 | Neurosearch A/S | Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetylcholine receptors |
| EP1047691A1 (en) * | 1997-12-12 | 2000-11-02 | Smithkline Beecham Plc | Quinolinepiperazine and quinolinepiperidine derivatives, their preparation and their use as combined 5-ht1a, 5-ht1b and 5-ht1d receptor antagonists |
| UA62015C2 (en) * | 1998-12-28 | 2003-12-15 | Pfizer Prod Inc | Benzoizoxazol derivatives, a pharmaceutical composition (variants) based thereon (variants) and a method for treatment (variants) |
| EP1106605A4 (en) | 1999-06-24 | 2005-12-07 | Toray Industries | ANTAGONISTS OF THE ADRENERGIC RECEPTOR-ALPHA1B |
| AU1028601A (en) * | 1999-11-05 | 2001-05-14 | Smithkline Beecham Plc | Isoquinoline and quinazoline derivatives having a combined 5ht1a, 5ht1b and 5ht1d receptor activity |
| HUP0301458A2 (hu) | 2000-10-26 | 2003-10-28 | Smithkline Beecham Plc. | Benzoxazinonszármazékok, eljárás előállításukra és a vegyületek felhasználása |
| CA2364211A1 (en) | 2000-12-05 | 2002-06-05 | Phillip Branch Chappell | Combination treatment for depression, anxiety and psychosis |
| GB0106419D0 (en) * | 2001-03-15 | 2001-05-02 | Smithkline Beecham Plc | Novel compounds |
| UY27304A1 (es) | 2001-05-24 | 2002-12-31 | Avanir Pharmaceuticals | Inhibidores del factor inhibidor de la migración de los macrófagos y métodos para su identificación |
| GB0203804D0 (en) | 2002-02-18 | 2002-04-03 | Glaxo Group Ltd | Compounds |
| GB0224084D0 (en) | 2002-10-16 | 2002-11-27 | Glaxo Group Ltd | Novel compounds |
| AU2003272030A1 (en) | 2002-11-08 | 2004-06-07 | Warner-Lambert Company Llc | Phenylalkyl and pyridylalkyl piperazine derivatives |
| GB0227240D0 (en) | 2002-11-21 | 2002-12-31 | Glaxo Group Ltd | Compounds |
| TW200418829A (en) | 2003-02-14 | 2004-10-01 | Avanir Pharmaceutics | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same |
| US6759435B1 (en) * | 2003-07-03 | 2004-07-06 | A.P. Group Inc. | Antidepressant drugs and methods |
| GB0316915D0 (en) * | 2003-07-18 | 2003-08-20 | Glaxo Group Ltd | Compounds |
| US20050124625A1 (en) | 2003-10-21 | 2005-06-09 | Salvati Mark E. | Piperazine derivatives and their use as modulators of nuclear hormone receptor function |
| WO2005087742A1 (en) | 2004-03-08 | 2005-09-22 | Exelixis, Inc. | Metabolic kinase modulators and methods of use as pesticides |
| NZ549254A (en) | 2004-03-10 | 2010-06-25 | Nycomed Gmbh | Amido-substituted hydroxy-6-phenylphenanthridines and their use as PDE4 inhibitors |
| PE20060653A1 (es) | 2004-08-31 | 2006-09-27 | Glaxo Group Ltd | Derivados triciclicos condensados como moduladores del receptor 5-ht1 |
-
2003
- 2003-07-18 GB GBGB0316915.8A patent/GB0316915D0/en not_active Ceased
-
2004
- 2004-07-15 KR KR1020067001103A patent/KR20060041242A/ko not_active Ceased
- 2004-07-15 DK DK04763307T patent/DK1646613T3/da active
- 2004-07-15 AU AU2004263268A patent/AU2004263268B2/en not_active Ceased
- 2004-07-15 EP EP09175186A patent/EP2145622A1/en not_active Withdrawn
- 2004-07-15 ES ES04763307T patent/ES2302543T3/es not_active Expired - Lifetime
- 2004-07-15 US US10/565,066 patent/US7279481B2/en not_active Expired - Fee Related
- 2004-07-15 PT PT04763307T patent/PT1646613E/pt unknown
- 2004-07-15 WO PCT/EP2004/008000 patent/WO2005014552A1/en not_active Ceased
- 2004-07-15 CN CNB2004800270575A patent/CN100441571C/zh not_active Expired - Fee Related
- 2004-07-15 DE DE602004012564T patent/DE602004012564T2/de not_active Expired - Lifetime
- 2004-07-15 PL PL04763307T patent/PL1646613T3/pl unknown
- 2004-07-15 MX MXPA06000716A patent/MXPA06000716A/es active IP Right Grant
- 2004-07-15 SI SI200430699T patent/SI1646613T1/sl unknown
- 2004-07-15 CA CA002532452A patent/CA2532452A1/en not_active Abandoned
- 2004-07-15 AT AT07118193T patent/ATE448205T1/de not_active IP Right Cessation
- 2004-07-15 HR HR20080226T patent/HRP20080226T3/xx unknown
- 2004-07-15 ES ES07118193T patent/ES2336148T3/es not_active Expired - Lifetime
- 2004-07-15 BR BRPI0412695-5A patent/BRPI0412695A/pt not_active IP Right Cessation
- 2004-07-15 EP EP04763307A patent/EP1646613B1/en not_active Expired - Lifetime
- 2004-07-15 JP JP2006520756A patent/JP2006528146A/ja not_active Ceased
- 2004-07-15 AT AT04763307T patent/ATE389637T1/de active
- 2004-07-15 NZ NZ544586A patent/NZ544586A/en unknown
- 2004-07-15 DE DE602004024141T patent/DE602004024141D1/de not_active Expired - Lifetime
- 2004-07-15 RU RU2006104993/04A patent/RU2402533C2/ru not_active IP Right Cessation
- 2004-07-15 EP EP07118193A patent/EP1876174B1/en not_active Expired - Lifetime
- 2004-07-16 TW TW093121227A patent/TW200521115A/zh unknown
- 2004-07-16 AR ARP040102527A patent/AR046394A1/es not_active Application Discontinuation
-
2006
- 2006-01-09 IL IL173036A patent/IL173036A0/en unknown
- 2006-01-18 MA MA28738A patent/MA27926A1/fr unknown
- 2006-02-15 IS IS8304A patent/IS2744B/is unknown
- 2006-02-17 NO NO20060774A patent/NO20060774L/no not_active Application Discontinuation
-
2007
- 2007-03-16 US US11/687,098 patent/US7459456B2/en not_active Expired - Fee Related
-
2008
- 2008-05-29 CY CY20081100555T patent/CY1107974T1/el unknown
- 2008-07-02 US US12/166,547 patent/US7592346B2/en not_active Expired - Fee Related
-
2009
- 2009-08-13 US US12/540,452 patent/US7732600B2/en not_active Expired - Fee Related
-
2010
- 2010-04-23 US US12/766,053 patent/US20100204273A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MXPA06000716A (es) | Derivados de quinolina y quinazolina que tienen afinidad hacia receptores del tipo 5ht1. | |
| ATE324371T1 (de) | N-substituierte heterocyclische nichtaryl- nmda/nr2b-antagonisten | |
| HRP20090281T1 (hr) | 1,2,3,4-tetrasubstituirani indol za liječenje respiratornih bolesti | |
| GEP20074055B (en) | Nicotinamide derivatives useful as pde4 inhibitors | |
| NO20044731L (no) | Kinolin- og isokinolinderivater fremgangsmate for fremstilling derav og anvendelse derav som betennelseshemmere | |
| DE60215000D1 (de) | DIHYDROPYRROLOi1,2-AöINDOL- UND TETRAHYDROPYRIDOi1,2-AöINDOLDERIVATE ALS PROSTAGLANDIN REZEPTOR ANTAGONISTEN | |
| DE60334015D1 (de) | Pyridopyrrolizin- und pyridoindolizinderivate | |
| YU37904A (sh) | Benzimidazoli kao korisni inhibitori proteinske kinaze | |
| NO20066055L (no) | Pyridinderivater | |
| NO20080670L (no) | Substituerte piperaziner som metabotrofiske glutamatreseptorantagonister | |
| ATE307810T1 (de) | Imidazol-2-carbonsäureamid derivate als raf- kinase-inhibitoren | |
| SG171471A1 (en) | New benzimidazole derivatives | |
| NO20062020L (no) | 1-amino-2-oksysubstituerte tetrahydronaftalenderivater, fremgangsmate for fremstilling derav, og deres anvendelse som antiflogistika | |
| UA88012C2 (uk) | Похідні хіназоліндіону як інгібітори parp | |
| GB0426313D0 (en) | Therapeutic agents | |
| ATE374190T1 (de) | Tetrahydrochinazolinderivate als cfr-antagonisten | |
| GB0308201D0 (en) | Novel compounds | |
| PE20030061A1 (es) | 1-biaril-1,8-naftiridin-4-ona como inhibidores de fosfodiesterasa-4 | |
| NO20080033L (no) | Kinolinderivater som NK3-antagonister | |
| NO20064238L (no) | Imidazolinderivater med CB1 agonistlsk aktivitet | |
| WO2004067703A3 (en) | 5ht7 antagonists and inverse agonists | |
| NO20080669L (no) | Acetylenpiperaziner som metabotrofiske glutamatreseptorantagonister | |
| MX2009003974A (es) | N-(2-hidroxietil)-n-metil-4-(quinolin-8-il(1-(tiazol-4-ilmetil)pi peridin-4-ilideno)metil)benzamida, el proceso para su sintesis, asi como su uso para el tratamiento del dolor, la ansiedad y la depresion. | |
| TW200628153A (en) | Novel compounds | |
| CR8955A (es) | Hexadecasacaridos biotinilados, su preparacion y su utilizacion |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |