NO20055883L - Fremgangsmate for fremstilling av racemisk 2-{[2-(4-hydroksfenyl)etyl]tio}-3-[4-(2-{4-[(metylsulfonyl)oksy]fenoksy}etyl)fenyl]-propansyre - Google Patents

Fremgangsmate for fremstilling av racemisk 2-{[2-(4-hydroksfenyl)etyl]tio}-3-[4-(2-{4-[(metylsulfonyl)oksy]fenoksy}etyl)fenyl]-propansyre

Info

Publication number
NO20055883L
NO20055883L NO20055883A NO20055883A NO20055883L NO 20055883 L NO20055883 L NO 20055883L NO 20055883 A NO20055883 A NO 20055883A NO 20055883 A NO20055883 A NO 20055883A NO 20055883 L NO20055883 L NO 20055883L
Authority
NO
Norway
Prior art keywords
ethyl
methylsulfonyl
thio
hydroxyphenyl
phenoxy
Prior art date
Application number
NO20055883A
Other languages
English (en)
Norwegian (no)
Inventor
Henrik Sorensen
Kjell Andersson
Eva-Lotte Lindstedt Alstermark
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20055883L publication Critical patent/NO20055883L/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896Compounds having one or more Si-O-acyl linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/56Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO20055883A 2003-06-19 2005-12-12 Fremgangsmate for fremstilling av racemisk 2-{[2-(4-hydroksfenyl)etyl]tio}-3-[4-(2-{4-[(metylsulfonyl)oksy]fenoksy}etyl)fenyl]-propansyre NO20055883L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0314260.1A GB0314260D0 (en) 2003-06-19 2003-06-19 Therapeutic agents
PCT/GB2004/002599 WO2004113285A1 (en) 2003-06-19 2004-06-16 Process for the preparation of racemic 2-{[2-(4-hydroxyphenyl)ethyl]thio}-3-[4-(2-{4-[(methylsulfonyl)oxy]phenoxy}ethyl)phenyl]-propanoic acid

Publications (1)

Publication Number Publication Date
NO20055883L true NO20055883L (no) 2006-01-09

Family

ID=27636892

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055883A NO20055883L (no) 2003-06-19 2005-12-12 Fremgangsmate for fremstilling av racemisk 2-{[2-(4-hydroksfenyl)etyl]tio}-3-[4-(2-{4-[(metylsulfonyl)oksy]fenoksy}etyl)fenyl]-propansyre

Country Status (14)

Country Link
US (1) US7429675B2 (enExample)
EP (1) EP1638929A1 (enExample)
JP (1) JP2006527751A (enExample)
KR (1) KR20060010840A (enExample)
CN (1) CN1835918A (enExample)
AU (1) AU2004249487A1 (enExample)
BR (1) BRPI0411450A (enExample)
CA (1) CA2529252A1 (enExample)
GB (1) GB0314260D0 (enExample)
IL (1) IL172376A0 (enExample)
MX (1) MXPA05013716A (enExample)
NO (1) NO20055883L (enExample)
WO (1) WO2004113285A1 (enExample)
ZA (1) ZA200509944B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0104333D0 (sv) 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents
PL375074A1 (en) 2002-06-20 2005-11-14 Astrazeneca Ab Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance
GB0314075D0 (en) * 2003-06-18 2003-07-23 Astrazeneca Ab Therapeutic agents
GB0427524D0 (en) 2004-12-16 2005-01-19 Astrazeneca Ab Chemical process
KR101558005B1 (ko) * 2007-03-08 2015-10-06 알비레오 에이비 2-치환-3-페닐프로피온산 유도체 및 염증성 장 질환 치료에서의 그의 용도
FR2986804A1 (fr) * 2012-02-09 2013-08-16 Servier Lab Procede de synthese enzymatique de l'acide (7s) 3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene 7-carboxylique ou de ses esters, et application a la synthese de l'ivabradine et de ses sels

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61197530A (ja) 1985-02-25 1986-09-01 Mitsubishi Gas Chem Co Inc ラセミ化法
EP0193113B1 (en) * 1985-02-25 1992-01-22 Mitsubishi Gas Chemical Company, Inc. Process for optically isomerizing optically active alpha-amino acid amides and process for producing optically active alpha-amino acids
TW472047B (en) * 1994-02-04 2002-01-11 Merck & Co Inc Process for making HIV protease inhibitors
MA26634A1 (fr) * 1998-06-04 2004-12-20 Astra Ab Nouveaux derives de l'acide 3-aryl propionique et analogues
SE9801992D0 (sv) 1998-06-04 1998-06-04 Astra Ab New 3-aryl-2-hydroxypropionic acid derivative I
SE0104333D0 (sv) * 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents

Also Published As

Publication number Publication date
CA2529252A1 (en) 2004-12-29
MXPA05013716A (es) 2006-03-08
EP1638929A1 (en) 2006-03-29
US7429675B2 (en) 2008-09-30
US20060167309A1 (en) 2006-07-27
IL172376A0 (en) 2009-02-11
KR20060010840A (ko) 2006-02-02
BRPI0411450A (pt) 2006-07-18
GB0314260D0 (en) 2003-07-23
WO2004113285A1 (en) 2004-12-29
CN1835918A (zh) 2006-09-20
JP2006527751A (ja) 2006-12-07
AU2004249487A1 (en) 2004-12-29
ZA200509944B (en) 2006-12-27

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