NO20052922L - Fremgangsmate og sammensetninger for induksjon av apoptosis hos cancerceller - Google Patents

Fremgangsmate og sammensetninger for induksjon av apoptosis hos cancerceller

Info

Publication number
NO20052922L
NO20052922L NO20052922A NO20052922A NO20052922L NO 20052922 L NO20052922 L NO 20052922L NO 20052922 A NO20052922 A NO 20052922A NO 20052922 A NO20052922 A NO 20052922A NO 20052922 L NO20052922 L NO 20052922L
Authority
NO
Norway
Prior art keywords
cancer cells
compositions
methods
inducing apoptosis
apoptosis
Prior art date
Application number
NO20052922A
Other languages
English (en)
Other versions
NO20052922D0 (no
Inventor
Quinn L Deveraux
Deborah A Knee
Pedro Aza-Blanc
Garret M Hampton
Marc Nasoff
Klaus Wagner
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irm Llc filed Critical Irm Llc
Publication of NO20052922D0 publication Critical patent/NO20052922D0/no
Publication of NO20052922L publication Critical patent/NO20052922L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/207—Modifications characterised by siRNA, miRNA

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Sammendrag Det beskrives anti-DR4- eller anti-DR5-antistoffagonister, kombinert med apoptoseinduserende midler, som synergistisk induserer apoptose i cancerceller.
NO20052922A 2002-11-27 2005-06-15 Fremgangsmate og sammensetninger for induksjon av apoptosis hos cancerceller NO20052922L (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42984202P 2002-11-27 2002-11-27
US44896003P 2003-02-21 2003-02-21
US49471403P 2003-08-12 2003-08-12
US50490103P 2003-09-22 2003-09-22
PCT/US2003/037940 WO2004050895A2 (en) 2002-11-27 2003-11-25 Methods and compositions for inducing apoptosis in cancer cells

Publications (2)

Publication Number Publication Date
NO20052922D0 NO20052922D0 (no) 2005-06-15
NO20052922L true NO20052922L (no) 2005-08-17

Family

ID=32475709

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052922A NO20052922L (no) 2002-11-27 2005-06-15 Fremgangsmate og sammensetninger for induksjon av apoptosis hos cancerceller

Country Status (17)

Country Link
US (2) US7229617B2 (no)
EP (1) EP1576179B1 (no)
JP (1) JP2006514096A (no)
KR (3) KR20090046973A (no)
AT (1) ATE481092T1 (no)
AU (1) AU2003297579A1 (no)
BR (1) BR0316737A (no)
CA (1) CA2507077A1 (no)
CO (1) CO5640147A2 (no)
DE (1) DE60334247D1 (no)
EC (1) ECSP055818A (no)
MX (1) MXPA05005726A (no)
NO (1) NO20052922L (no)
PL (1) PL210174B1 (no)
PT (1) PT1576179E (no)
RU (1) RU2379056C2 (no)
WO (1) WO2004050895A2 (no)

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US7361341B2 (en) 2001-05-25 2008-04-22 Human Genome Sciences, Inc. Methods of treating cancer using antibodies that immunospecifically bind to trail receptors
US20090226429A1 (en) * 2001-05-25 2009-09-10 Human Genome Sciences, Inc. Antibodies That Immunospecifically Bind to TRAIL Receptors
US20050214209A1 (en) * 2001-05-25 2005-09-29 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to TRAIL receptors
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AU2002361784A1 (en) * 2001-12-20 2003-07-09 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to trail receptors
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Also Published As

Publication number Publication date
US8173128B2 (en) 2012-05-08
RU2379056C2 (ru) 2010-01-20
RU2005120167A (ru) 2006-03-10
KR20090046973A (ko) 2009-05-11
ATE481092T1 (de) 2010-10-15
EP1576179A2 (en) 2005-09-21
EP1576179B1 (en) 2010-09-15
US20050079172A1 (en) 2005-04-14
JP2006514096A (ja) 2006-04-27
KR100915257B1 (ko) 2009-09-03
WO2004050895A2 (en) 2004-06-17
PL377726A1 (pl) 2006-02-06
WO2004050895A3 (en) 2005-12-08
CA2507077A1 (en) 2004-06-17
NO20052922D0 (no) 2005-06-15
EP1576179A4 (en) 2007-06-06
DE60334247D1 (de) 2010-10-28
AU2003297579A1 (en) 2004-06-23
PT1576179E (pt) 2010-12-21
ECSP055818A (es) 2006-01-27
US7229617B2 (en) 2007-06-12
US20070128204A1 (en) 2007-06-07
MXPA05005726A (es) 2005-08-16
BR0316737A (pt) 2005-12-13
PL210174B1 (pl) 2011-12-30
KR20050094811A (ko) 2005-09-28
CO5640147A2 (es) 2006-05-31
KR20070122578A (ko) 2007-12-31

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