NO20051965L - Nye piperidinderivater for anvendelse ved behandling av kemokinmedierte sykdomstilstander. - Google Patents

Nye piperidinderivater for anvendelse ved behandling av kemokinmedierte sykdomstilstander.

Info

Publication number
NO20051965L
NO20051965L NO20051965A NO20051965A NO20051965L NO 20051965 L NO20051965 L NO 20051965L NO 20051965 A NO20051965 A NO 20051965A NO 20051965 A NO20051965 A NO 20051965A NO 20051965 L NO20051965 L NO 20051965L
Authority
NO
Norway
Prior art keywords
chemokine
treatment
mediated disease
disease states
piperidine derivatives
Prior art date
Application number
NO20051965A
Other languages
English (en)
Other versions
NO20051965D0 (no
Inventor
Brian Springthorpe
Matthew Perry
Christopher Luckhurst
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20051965D0 publication Critical patent/NO20051965D0/no
Publication of NO20051965L publication Critical patent/NO20051965L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
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    • A61P31/12—Antivirals
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    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
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    • A61P37/02—Immunomodulators
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    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Abstract

Den foreliggende oppfinnelsen tilveiebringer en forbindelse vist ved formel (I) og hvor variablene er definert, en fremgangsmåte for å fremstille en slik forbindelse og anvendelsen av en slik forbindelse i behandlingen av kjemokin- (som CCR3) og Hl-medierte sykdomstilstander.
NO20051965A 2002-09-24 2005-04-22 Nye piperidinderivater for anvendelse ved behandling av kemokinmedierte sykdomstilstander. NO20051965L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0202838A SE0202838D0 (sv) 2002-09-24 2002-09-24 Chemical compounds
PCT/SE2003/001425 WO2004029041A1 (en) 2002-09-24 2003-09-12 Novel piperidine derivatives for use in the treatment of chemokine mediated disease states

Publications (2)

Publication Number Publication Date
NO20051965D0 NO20051965D0 (no) 2005-04-22
NO20051965L true NO20051965L (no) 2005-06-23

Family

ID=20289093

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20051965A NO20051965L (no) 2002-09-24 2005-04-22 Nye piperidinderivater for anvendelse ved behandling av kemokinmedierte sykdomstilstander.

Country Status (20)

Country Link
US (1) US20060040984A1 (no)
EP (2) EP1546130B1 (no)
JP (1) JP2006503066A (no)
KR (1) KR20050052511A (no)
CN (1) CN1684952A (no)
AT (1) ATE368656T1 (no)
AU (1) AU2003259004B2 (no)
BR (1) BR0314688A (no)
CA (1) CA2497280A1 (no)
DE (1) DE60315323T2 (no)
ES (1) ES2289354T3 (no)
IS (1) IS7813A (no)
MX (1) MXPA05003007A (no)
NO (1) NO20051965L (no)
NZ (1) NZ538527A (no)
PL (1) PL376119A1 (no)
RU (1) RU2005105053A (no)
SE (1) SE0202838D0 (no)
WO (1) WO2004029041A1 (no)
ZA (1) ZA200502341B (no)

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SE0200844D0 (sv) * 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
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SE0300850D0 (sv) * 2003-03-25 2003-03-25 Astrazeneca Ab Chemical compounds
SE0300957D0 (sv) * 2003-04-01 2003-04-01 Astrazeneca Ab Chemical compounds
SE0301368D0 (sv) * 2003-05-09 2003-05-09 Astrazeneca Ab Chemical compounds

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SE0202838D0 (sv) 2002-09-24
MXPA05003007A (es) 2005-06-22
AU2003259004A1 (en) 2004-04-19
NO20051965D0 (no) 2005-04-22
EP1546130A1 (en) 2005-06-29
ATE368656T1 (de) 2007-08-15
NZ538527A (en) 2006-10-27
PL376119A1 (en) 2005-12-12
EP1816123A1 (en) 2007-08-08
WO2004029041A1 (en) 2004-04-08
DE60315323T2 (de) 2008-04-17
CA2497280A1 (en) 2004-04-08
DE60315323D1 (de) 2007-09-13
IS7813A (is) 2005-04-20
ES2289354T3 (es) 2008-02-01
KR20050052511A (ko) 2005-06-02
AU2003259004B2 (en) 2007-02-08
CN1684952A (zh) 2005-10-19
ZA200502341B (en) 2005-09-19
RU2005105053A (ru) 2005-12-10
BR0314688A (pt) 2005-08-02
US20060040984A1 (en) 2006-02-23
JP2006503066A (ja) 2006-01-26
EP1546130B1 (en) 2007-08-01

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