NO20045483L - Bedring av utviklingen av katarakt og andre oftalmiske sykdommer - Google Patents
Bedring av utviklingen av katarakt og andre oftalmiske sykdommerInfo
- Publication number
- NO20045483L NO20045483L NO20045483A NO20045483A NO20045483L NO 20045483 L NO20045483 L NO 20045483L NO 20045483 A NO20045483 A NO 20045483A NO 20045483 A NO20045483 A NO 20045483A NO 20045483 L NO20045483 L NO 20045483L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- alkenyl
- cataracts
- development
- improvement
- Prior art date
Links
- 208000002177 Cataract Diseases 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 4
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 2
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 208000002780 macular degeneration Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A61K38/063—Glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38128702P | 2002-05-17 | 2002-05-17 | |
PCT/US2003/015948 WO2003096991A2 (fr) | 2002-05-17 | 2003-05-19 | Amelioration de l'evolution des cataractes et d'autres maladies ophtalmiques |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20045483L true NO20045483L (no) | 2004-12-16 |
Family
ID=29550095
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20045483A NO20045483L (no) | 2002-05-17 | 2004-12-16 | Bedring av utviklingen av katarakt og andre oftalmiske sykdommer |
Country Status (13)
Country | Link |
---|---|
US (3) | US7442711B2 (fr) |
EP (1) | EP1507826A4 (fr) |
JP (1) | JP4615309B2 (fr) |
KR (1) | KR20060013632A (fr) |
CN (1) | CN100469776C (fr) |
AU (1) | AU2003243282B2 (fr) |
BR (1) | BR0310057A (fr) |
CA (1) | CA2484512C (fr) |
IL (1) | IL164639A (fr) |
MX (1) | MXPA04011416A (fr) |
NO (1) | NO20045483L (fr) |
WO (1) | WO2003096991A2 (fr) |
ZA (1) | ZA200408449B (fr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA200408449B (en) * | 2002-05-17 | 2007-09-26 | Othera Pharmaceuticals Inc | Amelioration of the development of cataracts and other opthalmic diseases |
US20040057983A1 (en) | 2002-09-25 | 2004-03-25 | David Schmidt | Biomolecular wearable apparatus |
WO2004062576A2 (fr) * | 2003-01-03 | 2004-07-29 | Bernstein Eric F | Procedes pour le traitement de maladies oculaires avec des composes contenant de l'acide nitroxide et/ou polyhydroxy |
US7589107B2 (en) * | 2003-05-19 | 2009-09-15 | Othera Holding, Inc. | Amelioration of vitrectomy-induced cataracts |
US7825134B2 (en) * | 2003-05-19 | 2010-11-02 | Othera Holding, Inc. | Amelioration of cataracts, macular degeneration and other ophthalmic diseases |
WO2005055926A2 (fr) * | 2003-11-20 | 2005-06-23 | Othera Pharmaceuticals, Inc. | Amelioration de la cataracte, de la degenerescence maculaire et autres maladies ophtalmiques |
EP1689397A4 (fr) * | 2003-11-20 | 2007-06-20 | Othera Pharmaceuticals Inc | Amelioration de la degenerescence maculaire et d'autres maladies ophtalmiques |
US20080312283A1 (en) * | 2005-05-26 | 2008-12-18 | Othera Pharmaceuticals, Inc. | Use of Hydroxylamine Derivates for Inhibiting Vitrectomy-Induced Cataracts |
US20070197599A1 (en) * | 2006-02-02 | 2007-08-23 | Matier William L | Hydroxylamines and derivatives as anti-angiogenic agents |
US20070197593A1 (en) * | 2006-02-22 | 2007-08-23 | Matier William L | Hydroxylamines and derivatives for treatment of inflammatory conditions of the liver |
US20070203190A1 (en) * | 2006-02-22 | 2007-08-30 | Ghanshyam Patil | Hydroxylamines and derivatives for the inhibition of complement activation |
EP2120942A2 (fr) * | 2007-02-16 | 2009-11-25 | Othera Holding, Inc. | Inversion de la résistance à des médicaments dans une maladie néoplasique |
CA2679066A1 (fr) | 2007-02-22 | 2008-08-28 | Othera Holding, Inc. | Composes d'hydroxylamine et leurs procedes d'utilisation |
EP2217589A4 (fr) * | 2007-11-28 | 2012-02-22 | Revision Therapeutics Inc | Modulateurs de stress oxydatif oculaire |
US8602961B2 (en) * | 2008-05-15 | 2013-12-10 | Lifewave Products Llc | Apparatus and method of stimulating elevation of glutathione levels in a subject |
EP2493293B1 (fr) | 2009-10-30 | 2016-03-02 | Nestec S.A. | Procédés de maintien de la santé oculaire et d'amélioration des maladies ophtalmiques chez les canidés |
US8778969B2 (en) | 2009-11-07 | 2014-07-15 | Peter H Proctor | Nitrone, nitroso, and nitroxide spintraps and spin labels and their hydroxylamines |
EP2397474A1 (fr) * | 2010-06-17 | 2011-12-21 | Construction Research & Technology GmbH | Esters d'acide carboxylique 2-Oxo-1,3-dioxolane-4, leur fabrication et leur utilisation |
US9012647B2 (en) | 2011-04-07 | 2015-04-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Nitroxide modified non-steroidal anti-inflammatory compounds and uses thereof in the treatment and prevention of diseases or disorders |
EP2514800B2 (fr) * | 2011-04-21 | 2018-03-07 | Merck Patent GmbH | Composés et milieu liquide cristallin |
WO2013092011A1 (fr) * | 2011-12-22 | 2013-06-27 | Construction Research & Technology Gmbh | 2-oxo-1,3-dioxolane-4-carboxamides, leur préparation et leur utilisation |
CN102584683B (zh) * | 2012-02-29 | 2014-12-24 | 中国人民解放军第四军医大学 | Tempol类衍生物的合成及辐射防护作用 |
EP2818465A1 (fr) * | 2013-06-26 | 2014-12-31 | Construction Research & Technology GmbH | 4-Halogenure d'acyle de 2-oxo-1,3-dioxolane, leur préparation et leur utilisation |
US9314457B2 (en) | 2014-06-19 | 2016-04-19 | The University Of Utah Research Foundation | Methods of treating and preventing vascular instability diseases |
PL441664A1 (pl) * | 2022-07-07 | 2024-01-08 | Uniwersytet Warszawski | Nitroksylowa pochodna polifenolu, sposoby jej wytwarzania oraz jej zastosowanie |
Family Cites Families (116)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3936456A (en) * | 1972-03-24 | 1976-02-03 | Ciby-Geigy Corporation | Substituted piperazine dione oxyls and hydroxides and polymer compositions stabilized thereby |
US4014335A (en) | 1975-04-21 | 1977-03-29 | Alza Corporation | Ocular drug delivery device |
NL188266C (nl) | 1975-07-29 | 1992-05-18 | Merck & Co Inc | Werkwijze ter bereiding van een oogheelkundig inplantaat. |
US4287175A (en) | 1978-06-22 | 1981-09-01 | Merck & Co., Inc. | Contact lens wetting agents |
JPS5899449A (ja) | 1981-12-09 | 1983-06-13 | Sanyo Chem Ind Ltd | カチオン性ビニルモノマ−の安定化法 |
US4404302A (en) | 1982-05-27 | 1983-09-13 | Ferro Corporation | Acylated hindered hexahydropyrimidines and their use as light stabilizing agents |
US4590231A (en) | 1983-10-11 | 1986-05-20 | Ciba-Geigy Corporation | Polyolefin compositions stabilized against degradation using hydroxylamine derivatives |
US4983392A (en) | 1983-11-14 | 1991-01-08 | Bio-Mimetics, Inc. | Bioadhesive compositions and methods of treatment therewith |
EP0501523B1 (fr) | 1983-11-14 | 1997-04-09 | Columbia Laboratories, Inc. | Compositions bioadhésives |
US5225196A (en) | 1983-11-14 | 1993-07-06 | Columbia Laboratories, Inc. | Bioadhesive compositions and methods of treatment therewith |
EP0157738B1 (fr) | 1984-03-22 | 1989-04-19 | Ciba-Geigy Ag | Procédé pour la préparation de radicaux nitroxydes d'amines stériquement encombrés |
US4691015A (en) * | 1984-07-23 | 1987-09-01 | Ciba-Geigy Corporation | Hydroxylamines derived from hindered amines |
US5209927A (en) | 1985-01-23 | 1993-05-11 | Alcon Laboratories, Inc. | Ophthalmic solution |
US4668699A (en) * | 1985-08-05 | 1987-05-26 | Merck & Co., Inc. | Novel HMG-CoA reductase inhibitors |
US4883658A (en) | 1986-04-28 | 1989-11-28 | Holly Frank J | Ophthalmic solution for treatment of dry-eye syndrome |
US4804539A (en) | 1986-07-28 | 1989-02-14 | Liposome Technology, Inc. | Ophthalmic liposomes |
JPS6385547A (ja) | 1986-09-29 | 1988-04-16 | Fuji Photo Film Co Ltd | ハロゲン化銀カラ−写真感光材料 |
US4818537A (en) | 1986-10-21 | 1989-04-04 | Liposome Technology, Inc. | Liposome composition for treating dry eye |
FR2608045B1 (fr) | 1986-12-12 | 1990-03-02 | Chauvin Laboratoires | Utilisation d'inhibiteurs de xanthine- oxydase, de piegeurs de radicaux libres oxygenes et de chelateurs du fer pour la fabrication d'une composition pharmaceutique destinee au traitement du glaucome et compositions pharmaceutiques destinees au traitement du glaucome |
US4914088A (en) | 1987-04-02 | 1990-04-03 | Thomas Glonek | Dry eye treatment solution and method |
US5278151A (en) | 1987-04-02 | 1994-01-11 | Ocular Research Of Boston, Inc. | Dry eye treatment solution |
EP0309400B1 (fr) | 1987-09-21 | 1994-03-02 | Ciba-Geigy Ag | N-acyloxyamines stabilisantes à empêchement stérique |
DE3851931T2 (de) | 1987-09-21 | 1995-03-16 | Ciba Geigy Ag | Stabilisierung einer Beschichtung mit sterisch gehinderten N-hydroxysubstituierten Aminen. |
DE3801790A1 (de) | 1988-01-22 | 1989-07-27 | Resart Ihm Ag | Kunststoffmaterial mit hoher uv-durchlaessigkeit, verfahren zu dessen herstellung und dessen verwendung |
EP0352221B1 (fr) | 1988-06-14 | 1994-03-09 | Ciba-Geigy Ag | Procédé de stabilisation photochimique de fibres en polypropylène teint ou non teint |
US5073278A (en) | 1988-07-18 | 1991-12-17 | Ciba-Geigy Corporation | Lubricant composition |
US5004770A (en) * | 1988-10-19 | 1991-04-02 | Ciba-Geigy Corporation | Polymeric substrates stabilized with N-substituted hindered amines |
US4927891A (en) * | 1988-11-23 | 1990-05-22 | Pennwalt Corporation | Polymer bound light stabilizer coating resins |
US5030243A (en) | 1989-01-05 | 1991-07-09 | Ciba-Geigy Corporation | Process for the photochemical stabilization of undyed and dyeable artificial leather with a sterically hindered amine |
DE4000551A1 (de) | 1989-01-13 | 1990-07-19 | Ciba Geigy Ag | Verfahren zum fotochemischen stabilisieren von gefaerbter wolle |
US5145893A (en) | 1989-03-21 | 1992-09-08 | Ciba-Geigy Corporation | Non-migrating 1-hydrocarbyloxy hindered amine derivatives as polymer stabilizers |
US5075104A (en) | 1989-03-31 | 1991-12-24 | Alcon Laboratories, Inc. | Ophthalmic carboxy vinyl polymer gel for dry eye syndrome |
JPH0331342A (ja) | 1989-06-28 | 1991-02-12 | Mitsubishi Petrochem Co Ltd | ポリオレフィン樹脂組成物 |
DE59010484D1 (de) | 1989-11-08 | 1996-10-10 | Ciba Geigy Ag | Schmierstoffzusammensetzungen |
ATE249829T1 (de) | 1990-03-16 | 2003-10-15 | Us Secretary United States Dep | Verwendung von nitroxiden und oxazolidinen zum schutz ionisierender strahlung und oxidativem stress |
ZA912797B (en) | 1990-05-29 | 1992-12-30 | Boston Ocular Res | Dry eye treatment process and solution |
ES2084722T3 (es) | 1990-05-29 | 1996-05-16 | Boston Ocular Res | Composicion para tratamiento del ojo seco. |
US5290888A (en) | 1990-07-20 | 1994-03-01 | Ciba-Geigy Corporation | Process for stabilizing ethylenically unsaturated compounds and stabilized monomer compositions |
KR100193146B1 (ko) * | 1990-07-20 | 1999-06-15 | 월터 클리웨인, 한스-피터 위트린 | 안정화된 단량체 조성물 |
DE69112735T2 (de) | 1990-07-20 | 1996-02-22 | Ciba Geigy Ag | Stabilisierte Monomerenzusammensetzungen. |
JPH04166930A (ja) | 1990-10-31 | 1992-06-12 | Fuji Photo Film Co Ltd | ハロゲン化銀写真感光材料 |
US5475013A (en) * | 1990-11-19 | 1995-12-12 | Monsanto Company | Retroviral protease inhibitors |
FR2670517B1 (fr) | 1990-12-13 | 1993-04-09 | Normandie Const Meca | Element de franchissement pour le franchissement d'obstacles. |
CA2058823A1 (fr) | 1991-01-08 | 1992-07-09 | Rolf Schumacher | Compositions de lubrifiants |
IT1246779B (it) | 1991-04-12 | 1994-11-26 | Ciba Geigy Spa | Composti piperidinici atti all'impiego come stabilizzanti per materiali organici. |
US5399473A (en) * | 1991-04-12 | 1995-03-21 | Fuji Photo Film Company, Ltd. | Silver halide color photographic material |
JP2681424B2 (ja) | 1991-04-12 | 1997-11-26 | 富士写真フイルム株式会社 | ハロゲン化銀カラー写真感光材料 |
DK0565487T3 (da) | 1992-04-08 | 1997-05-20 | Ciba Geigy Ag | Flydende antioxidanter som stabilisatorer |
DE4327297B4 (de) | 1992-08-17 | 2007-05-24 | Clariant Finance (Bvi) Ltd. | Verwendung von Piperidinverbindungen |
US5874493A (en) | 1996-04-12 | 1999-02-23 | Clariant Finance (Bvi) Limited | Stabilization of polyolefins |
TW237471B (fr) | 1992-09-03 | 1995-01-01 | Ciba Geigy | |
JPH06172592A (ja) | 1992-12-09 | 1994-06-21 | Sumitomo Chem Co Ltd | カーボンブラック含有ポリオレフィン系樹脂組成物 |
US5707643A (en) | 1993-02-26 | 1998-01-13 | Santen Pharmaceutical Co., Ltd. | Biodegradable scleral plug |
CH688878B5 (de) | 1993-04-06 | 1998-11-13 | Ciba Geigy Ag | Handelsformen von sterisch gehindertem Amin und deren Verwendung. |
IT1270975B (it) | 1993-06-03 | 1997-05-26 | Ciba Geigy Spa | Composti piperidin-triazinici atti all'impiego come stabilizzanti allaluce, al calore e alla ossidazione per materiali organici |
DE4320444A1 (de) | 1993-06-21 | 1994-12-22 | Agfa Gevaert Ag | Farbfotografisches Aufzeichnungsmaterial |
IT1264946B1 (it) | 1993-07-16 | 1996-10-17 | Ciba Geigy Spa | Derivati del 2,2,6,6-tetrametil-4-piperidinolo utili come stabilizzanti alla luce ed all'ossidazione per materiali organici. |
IT1264817B1 (it) | 1993-07-28 | 1996-10-10 | Ciba Geigy Spa | Derivati di polialchil-4-piperidinoli atti all'impderivati di polialchil-4-piperidinoli atti all'impiego come stabilizzanti per materiali organici iego come stabilizzanti per materiali organici |
EP0638616A1 (fr) | 1993-08-13 | 1995-02-15 | Ciba-Geigy Ag | Sels de pigments |
CA2131047A1 (fr) | 1993-09-01 | 1995-03-02 | Takashi Sanada | Composition de resine thermoplastique |
GB9318846D0 (en) | 1993-09-10 | 1993-10-27 | Sandoz Ltd | Improvements in or relating to organic compounds |
TW327185B (en) | 1993-09-20 | 1998-02-21 | Ciba Sc Holding Ag | Liquid antioxidants |
WO1995017900A1 (fr) | 1993-12-30 | 1995-07-06 | Arcturus Pharmaceutical Corporation | Methodes de traitement de troubles du systeme nerveux central ou de l'oeil impliquant des voies d'oxydation pathogene |
DE59505941D1 (de) | 1994-01-19 | 1999-06-24 | Ciba Geigy Ag | Stabilisieren von Leder gegen thermische und photochemische Zersetzung |
US5466233A (en) | 1994-04-25 | 1995-11-14 | Escalon Ophthalmics, Inc. | Tack for intraocular drug delivery and method for inserting and removing same |
WO1996015110A1 (fr) | 1994-11-15 | 1996-05-23 | Moreno Paolini | N-hydroxypiperidines en tant qu'intercepteurs de radicaux superoxyde |
US5725493A (en) | 1994-12-12 | 1998-03-10 | Avery; Robert Logan | Intravitreal medicine delivery |
US5518732A (en) | 1995-02-14 | 1996-05-21 | Chiron Vision, Inc. | Bio-erodible ophthalmic shield |
IT1273607B (it) | 1995-04-26 | 1997-07-08 | Ciba Geigy Spa | Combinazione di stabilizzanti per polimeri sintetici organici |
US5699182A (en) | 1995-05-25 | 1997-12-16 | Xytronyx, Inc. | Light fatigue resistant photochromic formulations |
US5718922A (en) | 1995-05-31 | 1998-02-17 | Schepens Eye Research Institute, Inc. | Intravitreal microsphere drug delivery and method of preparation |
TW416970B (en) | 1995-05-31 | 2001-01-01 | Ciba Sc Holding Ag | Carrier-bound light stabilizers and antioxidants as fillers and stabilizers |
US5869079A (en) | 1995-06-02 | 1999-02-09 | Oculex Pharmaceuticals, Inc. | Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents |
US6469057B1 (en) * | 1995-06-02 | 2002-10-22 | Mcw Research Foundation, Inc. | Methods for in vivo reduction of free radical levels and compositions useful therefor |
JPH0952975A (ja) | 1995-08-18 | 1997-02-25 | Clariant Internatl Ltd | 顔料の安定化方法及びこの方法に用いる組成物 |
DE19530468A1 (de) | 1995-08-18 | 1997-02-20 | Sandoz Ag | Verwendung von Piperidinverbindungen |
EP0761466B1 (fr) | 1995-08-30 | 1999-08-04 | Eastman Kodak Company | Elément donneur de colorant stabilisé, utilisé pour le transfert thermique de colorant |
US5821374A (en) | 1995-11-21 | 1998-10-13 | Hoffmann-La Roche Inc. | Process for the oxidation of alcohols |
US6001853A (en) * | 1996-01-26 | 1999-12-14 | The United States Of America As Represented By The Department Of Health And Human Services | Hydroxylamine compositions for the prevention or retardation of cataracts |
GB9607565D0 (en) | 1996-04-12 | 1996-06-12 | Clariant Int Ltd | Stabilizer composition |
DE19618197A1 (de) | 1996-05-07 | 1997-11-13 | Hoechst Ag | Neue sterisch gehinderte Piperidinderivate als Lichtschutzmittel für Polymere |
JPH1045778A (ja) | 1996-07-29 | 1998-02-17 | Sakai Chem Ind Co Ltd | 新規なヒンダードアミン塩及びその用途 |
JPH1045777A (ja) | 1996-07-29 | 1998-02-17 | Sakai Chem Ind Co Ltd | 新規な有機リン化合物及びその用途 |
EP0946635B1 (fr) | 1996-12-19 | 2003-05-28 | ExxonMobil Chemical Patents Inc. | Procede de fusion de polyethylenes contenant des amines |
BR9714168A (pt) | 1996-12-20 | 2000-04-25 | Cia Speciality Chemicals Holdi | Catalisadores de trasesterificação fixados em materiais de suporte sólidos. |
EP0895474A4 (fr) * | 1997-01-29 | 2003-03-05 | A Glenn Braswell | Composition de collyre liquide |
US5981584A (en) | 1997-02-06 | 1999-11-09 | Merck & Co., Inc. | Fibrinogen receptor antagonist prodrugs |
JPH10219140A (ja) | 1997-02-07 | 1998-08-18 | Nippon Nsc Ltd | 耐候性塗料用樹脂エマルション |
JPH10220381A (ja) | 1997-02-07 | 1998-08-18 | Matsushita Refrig Co Ltd | 密閉型圧縮機 |
IT1291599B1 (it) | 1997-04-18 | 1999-01-11 | Great Lakes Chemical Italia | Composti appartenenti alla classe delle enammine e loro utilizzo come antiossidanti per polimeri organici |
DE19816681A1 (de) | 1997-04-18 | 1998-10-22 | Ciba Geigy Ag | Azidhaltige Stabilisatoren |
IT1302988B1 (it) | 1997-05-08 | 2000-10-18 | Great Lakes Chemical Italia | Polimeri organici stabilizzati alla luce |
WO1999005108A1 (fr) | 1997-07-23 | 1999-02-04 | Ciba Specialty Chemicals Holding Inc. | Inhibition du jaunissement de pate et de papier via des oxydes nitres et autres co-additifs |
DE19735255B4 (de) | 1997-08-14 | 2007-08-23 | Clariant Produkte (Deutschland) Gmbh | Synergistisches Stabilisatorgemisch auf Basis von Polyalkyl-1-oxa-diazaspirodecan-Verbindungen und dessen Verwendung |
US5902598A (en) | 1997-08-28 | 1999-05-11 | Control Delivery Systems, Inc. | Sustained release drug delivery devices |
FR2773165B1 (fr) | 1997-12-26 | 2001-06-08 | Rhodia Chimie Sa | Stabilisation des moules en elastomere silicone |
FR2773320B1 (fr) | 1998-01-05 | 2000-03-03 | Optisinvest | Dispositif pour le transfert intraoculaire de produits actifs par iontophorese |
DE19804910A1 (de) | 1998-02-07 | 1999-08-12 | Clariant Gmbh | Polyolefin-Formmasse zur Herstellung von kalandrierten Folien/Platten |
IT1298452B1 (it) | 1998-02-26 | 2000-01-10 | Great Lakes Chemical Italia | Composizioni fotocromatiche dotate di resistenza a fatica alla luce ed articoli fotocromatici che le contengono |
TWI224995B (en) | 1998-03-19 | 2004-12-11 | Ciba Sc Holding Ag | Stabilization of wood substrates |
US6149925A (en) | 1998-11-05 | 2000-11-21 | Color Access, Inc. | Topical compositions for enhancing glutathione production |
US6433007B1 (en) | 1998-12-17 | 2002-08-13 | Alcon Manufacturing, Ltd. | Methods for the prevention and treatment of post-surgical complications |
US6410045B1 (en) | 1999-02-22 | 2002-06-25 | Clyde Lewis Schultz | Drug delivery system for antiglaucomatous medication |
US6281192B1 (en) | 1999-03-01 | 2001-08-28 | Vista Scientific Llc | Mucin containing ophthalmic preparations |
US6429194B1 (en) | 1999-03-01 | 2002-08-06 | Vista Scientific Llc | Mucin containing ophthalmic preparation |
JP4375838B2 (ja) | 1999-05-21 | 2009-12-02 | 株式会社Adeka | ゴム組成物 |
TW514581B (en) | 1999-09-02 | 2002-12-21 | Ciba Sc Holding Ag | A method of protecting wood against light-induced degradation by treatment with an impregnation which penetrates the surface of the wood |
US6331313B1 (en) | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
US20010036943A1 (en) | 2000-04-07 | 2001-11-01 | Coe Jotham W. | Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines |
US6375972B1 (en) | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
WO2002000260A1 (fr) | 2000-06-29 | 2002-01-03 | Mitsubishi Pharma Corporation | Jp0105585atif contre des maladies du nerf optique et analogue |
IT1320080B1 (it) | 2000-10-25 | 2003-11-18 | Giuliani Spa | Composizione per uso farmaceutico o dietetico. |
US9358195B2 (en) * | 2002-05-02 | 2016-06-07 | Basf Se | Stabilized body care products, household products, textiles and fabrics |
ZA200408449B (en) | 2002-05-17 | 2007-09-26 | Othera Pharmaceuticals Inc | Amelioration of the development of cataracts and other opthalmic diseases |
US7825134B2 (en) | 2003-05-19 | 2010-11-02 | Othera Holding, Inc. | Amelioration of cataracts, macular degeneration and other ophthalmic diseases |
JP4288302B1 (ja) | 2008-01-18 | 2009-07-01 | トモデータサービス有限会社 | 位置検出装置および位置検出プログラム並びに施設図面データ |
-
2003
- 2003-05-19 ZA ZA200408449A patent/ZA200408449B/xx unknown
- 2003-05-19 CA CA2484512A patent/CA2484512C/fr not_active Expired - Fee Related
- 2003-05-19 AU AU2003243282A patent/AU2003243282B2/en not_active Ceased
- 2003-05-19 MX MXPA04011416A patent/MXPA04011416A/es active IP Right Grant
- 2003-05-19 JP JP2004504990A patent/JP4615309B2/ja not_active Expired - Fee Related
- 2003-05-19 EP EP03753107A patent/EP1507826A4/fr not_active Withdrawn
- 2003-05-19 KR KR1020047018566A patent/KR20060013632A/ko not_active Application Discontinuation
- 2003-05-19 BR BRPI0310057-0A patent/BR0310057A/pt not_active IP Right Cessation
- 2003-05-19 WO PCT/US2003/015948 patent/WO2003096991A2/fr active Search and Examination
- 2003-05-19 CN CNB038112213A patent/CN100469776C/zh not_active Expired - Fee Related
- 2003-05-19 US US10/440,583 patent/US7442711B2/en not_active Expired - Fee Related
-
2004
- 2004-10-17 IL IL164639A patent/IL164639A/en not_active IP Right Cessation
- 2004-12-16 NO NO20045483A patent/NO20045483L/no not_active Application Discontinuation
-
2008
- 2008-06-18 US US12/141,166 patent/US8383648B2/en not_active Expired - Fee Related
-
2012
- 2012-12-21 US US13/723,586 patent/US20130131052A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN100469776C (zh) | 2009-03-18 |
US20130131052A1 (en) | 2013-05-23 |
US8383648B2 (en) | 2013-02-26 |
CA2484512C (fr) | 2013-04-16 |
IL164639A (en) | 2012-02-29 |
AU2003243282A1 (en) | 2003-12-02 |
IL164639A0 (en) | 2005-12-18 |
ZA200408449B (en) | 2007-09-26 |
US7442711B2 (en) | 2008-10-28 |
WO2003096991A2 (fr) | 2003-11-27 |
JP4615309B2 (ja) | 2011-01-19 |
EP1507826A4 (fr) | 2007-11-07 |
CN1653125A (zh) | 2005-08-10 |
US20040002461A1 (en) | 2004-01-01 |
MXPA04011416A (es) | 2005-09-30 |
BR0310057A (pt) | 2007-04-10 |
EP1507826A2 (fr) | 2005-02-23 |
AU2003243282B2 (en) | 2008-05-01 |
JP2005527605A (ja) | 2005-09-15 |
WO2003096991A3 (fr) | 2004-02-26 |
KR20060013632A (ko) | 2006-02-13 |
CA2484512A1 (fr) | 2003-11-27 |
US20080274983A1 (en) | 2008-11-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20045483L (no) | Bedring av utviklingen av katarakt og andre oftalmiske sykdommer | |
ES476496A1 (es) | Procedimiento para preparar derivados de acido ftalazin-4- ilacetico. | |
CO5611127A2 (es) | Derivados de indolilmaleimida | |
CY1117132T1 (el) | Παραγωγο θειαζολιου | |
AR032436A1 (es) | Oxazolidinonas substituidas, procedimiento para su preparacion, medicamentos, el uso de las mismas para la fabricacion de medicamentos, y el metodo para impedir la coagulacion sanguinea in vitro | |
EA200100487A1 (ru) | Производные 2-аминотиазола, способ их получения и применение указанных веществ в качестве противоопухолевых средств | |
EA200501516A1 (ru) | Производные 2,3,6-тризамещённого-4-пиримидона | |
NO20093175L (no) | Trifenylalkylen-derivater og deres anvendelse som selektive ostrogen-reseptor-modulatorer | |
EA200600621A1 (ru) | Производные тетрагидронафталина, способ их получения и их применение в качестве противовоспалительных средств | |
DE69835877D1 (de) | Trizyklische verbindungen | |
HRP20070194T3 (en) | N-thiazol-2-yl-benzamide derivatives | |
DK0791006T3 (da) | Polyanioniske benzylglylcosider som inhibitorer af proliferation af glatte muskelceller | |
WO2008136444A1 (fr) | Dérivé hétérocyclique fusionné | |
TW200503712A (en) | (2-carboxamido)(3-amino)thiophene compounds | |
ES2187261A1 (es) | Compuestos de eteres y amidas y su preparacion, como agentes anti-diabeticos. | |
ATE175661T1 (de) | Benzamid-derivate als vasopressin-antagonisten | |
PA8573501A1 (es) | Derivados de benzoxazina y su empleo | |
NO20060079L (no) | 6-(1,1-Difluoralkyl)-4-Aminopikolinater og deres anvendelse som Herbicider | |
WO2005055926A3 (fr) | Amelioration de la cataracte, de la degenerescence maculaire et autres maladies ophtalmiques | |
MXPA05011125A (es) | Remedio preventivo para enfermedades del nervio retiniano que contienen derivados de eter de alquilo o sales de los mismos. | |
EA200401164A1 (ru) | Фунгицидные триазолопиримидины, способ их получения и их применение для борьбы с фитопатогенными грибами, а также содержащие их средства | |
CO6150165A2 (es) | Nevos derivados 5,7-disustituidos de [1,3]tiazolo[4,5-d]pirimidin-2 (3h)-ona y su uso en terapia | |
MXPA04003278A (es) | Derivados de 5-metoxi-8-aril-?1,2,4?triazolo?1,5-a?piridina como antagonistas del receptor de adenosina. | |
TW350838B (en) | Quinoline derivatives | |
JO2433B1 (en) | Preparation of heterocyclic lindane landscapes |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |