DK0791006T3 - Polyanioniske benzylglylcosider som inhibitorer af proliferation af glatte muskelceller - Google Patents

Polyanioniske benzylglylcosider som inhibitorer af proliferation af glatte muskelceller

Info

Publication number
DK0791006T3
DK0791006T3 DK95939897T DK95939897T DK0791006T3 DK 0791006 T3 DK0791006 T3 DK 0791006T3 DK 95939897 T DK95939897 T DK 95939897T DK 95939897 T DK95939897 T DK 95939897T DK 0791006 T3 DK0791006 T3 DK 0791006T3
Authority
DK
Denmark
Prior art keywords
image
smooth muscle
cell proliferation
inhibitors
muscle cell
Prior art date
Application number
DK95939897T
Other languages
English (en)
Inventor
Richard Michael Soll
Thomas The Nguyen
John Watson Ellingboe
Sarah Tobin Allen Novak
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Application granted granted Critical
Publication of DK0791006T3 publication Critical patent/DK0791006T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
DK95939897T 1994-11-07 1995-11-03 Polyanioniske benzylglylcosider som inhibitorer af proliferation af glatte muskelceller DK0791006T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/335,278 US5498775A (en) 1994-11-07 1994-11-07 Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation
PCT/US1995/014686 WO1996014323A1 (en) 1994-11-07 1995-11-03 Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation

Publications (1)

Publication Number Publication Date
DK0791006T3 true DK0791006T3 (da) 2000-04-17

Family

ID=23311066

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95939897T DK0791006T3 (da) 1994-11-07 1995-11-03 Polyanioniske benzylglylcosider som inhibitorer af proliferation af glatte muskelceller

Country Status (18)

Country Link
US (1) US5498775A (da)
EP (1) EP0791006B1 (da)
JP (1) JPH10508606A (da)
KR (1) KR970707139A (da)
AT (1) ATE189227T1 (da)
AU (1) AU702104B2 (da)
BR (1) BR9509606A (da)
DE (1) DE69514823T2 (da)
DK (1) DK0791006T3 (da)
ES (1) ES2141395T3 (da)
FI (1) FI971935A (da)
GR (1) GR3032629T3 (da)
IL (1) IL115746A (da)
MX (1) MX9703282A (da)
NZ (1) NZ296828A (da)
PT (1) PT791006E (da)
WO (1) WO1996014323A1 (da)
ZA (1) ZA959444B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6306421B1 (en) 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5770609A (en) 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US5595722A (en) 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6663881B2 (en) 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6197789B1 (en) 1995-06-07 2001-03-06 Neorx Corporation Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
UA52607C2 (uk) * 1995-06-29 2003-01-15 Тексіс Байотекнолоджі Корпорейшн Похідні біфенілів, фармацевтична композиція на їх основі та спосіб інгібування (варіанти)
US6001159A (en) * 1995-08-31 1999-12-14 Ricoh Company, Ltd. Reversible thermosensitive coloring composition and reversible thermosensitive recording medium using the same
US5919768A (en) * 1996-06-26 1999-07-06 Texas Biotechnology Corporation Di- and trivalent small molecule selectin inhibitors
US6451767B1 (en) 1998-11-24 2002-09-17 Wyeth Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6340670B1 (en) 1998-11-24 2002-01-22 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US7081448B2 (en) * 1998-11-24 2006-07-25 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6664243B1 (en) 1998-11-24 2003-12-16 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en) 1998-11-24 2002-03-26 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6291434B1 (en) 1998-11-24 2001-09-18 American Home Products Corp. Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en) 1998-11-24 2002-01-15 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
JP2003521460A (ja) * 1998-11-24 2003-07-15 ワイス 平滑筋細胞増殖の阻害薬としてのアセチル化ベンジルマルトシド
US6258784B1 (en) 1998-11-24 2001-07-10 American Home Products Corp. Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en) * 1998-11-24 2006-11-07 Wyeth Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6187755B1 (en) 1998-11-24 2001-02-13 American Home Products Corporation Benzylmaltosides as inhibitors of smooth muscle cell proliferation
US8106071B2 (en) 2007-02-21 2012-01-31 Biobud Co., Ltd. Compositions for treating hyperproliferative vascular disorders and cancers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431636A (en) * 1982-05-24 1984-02-14 American Cyanamid Company Bis(4-O-polyhexaose-thio)-phenyl ureas and method of use
US4431637A (en) * 1982-10-25 1984-02-14 American Cyanamid Company Polycation salts of bis (or tris) [4-O-polyhexose-oxy]-arylene sulfate derivatives
US4431638A (en) * 1982-10-25 1984-02-14 American Cyanamid Company Poly-cation salts of bis(or tris)[4-0-monohexose-thio]-arylene sulfate derivatives
US4435387A (en) * 1982-10-25 1984-03-06 American Cyanamid Company Poly-cation salts of bis (or tris) 4-O-polyhexose-thio-arylene sulfate derivatives
DE3734815A1 (de) * 1987-10-14 1989-04-27 Luitpold Werk Chem Pharm Polyschwefelsaeureester von bis-aldonsaeureamiden und deren derivaten, verfahren zu ihrer herstellung und arzneimittel
DE3734853A1 (de) * 1987-10-14 1989-04-27 Luitpold Werk Chem Pharm Bis-aldonsaeureamide und verfahren zu ihrer herstellung
US5019562A (en) * 1988-01-19 1991-05-28 The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation Growth inhibiting agent and the use thereof
FR2634485B1 (fr) * 1988-07-21 1992-02-28 Sanopi Glycosaminoglycanes selectivement o-acyles, leur preparation et compositions pharmaceutiques les contenant
US5032679A (en) * 1988-12-15 1991-07-16 Glycomed, Inc. Heparin fragments as inhibitors of smooth muscle cell proliferation
EP0454220B1 (en) * 1990-04-23 1993-08-18 Akzo Nobel N.V. Carbohydrate derivatives comprising a trisaccharide unit
EP0612249A4 (en) * 1991-11-11 1995-11-08 Univ Pennsylvania Methods of inhibiting restenosis.

Also Published As

Publication number Publication date
EP0791006A2 (en) 1997-08-27
PT791006E (pt) 2000-06-30
DE69514823T2 (de) 2000-10-12
EP0791006B1 (en) 2000-01-26
GR3032629T3 (en) 2000-05-31
MX9703282A (es) 1997-08-30
ES2141395T3 (es) 2000-03-16
US5498775A (en) 1996-03-12
ATE189227T1 (de) 2000-02-15
JPH10508606A (ja) 1998-08-25
NZ296828A (en) 1999-04-29
IL115746A (en) 1999-11-30
WO1996014323A1 (en) 1996-05-17
BR9509606A (pt) 1997-10-28
FI971935A0 (fi) 1997-05-06
FI971935A (fi) 1997-05-06
IL115746A0 (en) 1996-01-19
KR970707139A (ko) 1997-12-01
ZA959444B (en) 1997-08-07
AU4154996A (en) 1996-05-31
DE69514823D1 (de) 2000-03-02
AU702104B2 (en) 1999-02-11

Similar Documents

Publication Publication Date Title
DK0791006T3 (da) Polyanioniske benzylglylcosider som inhibitorer af proliferation af glatte muskelceller
DK0791005T3 (da) Inhibitorer af proliferation af glatte muskelceller
DK57281A (da) Fremgangsmaade til fremstilling af substituerede imidazolderivater eller syreadditionssalte deraf
DK44682A (da) Fremgangsmaade til fremstilling af substituerede imidazolderivater
DK0791004T3 (da) Acylerede benzylglykosider som inhibitorer af glat-muskelceller-proliferation
AU8686991A (en) New 3-cycloalkyl-propanamides, their tautomer forms and their salts, preparation process, use as medicaments and compositions containing them
ES483289A1 (es) Un procedimiento para la preparacion de 1,2,3,5, tetrahidro-himidazotienopirimidin-2-onas.
SE8406302D0 (sv) New aminoguanidine derivatives and a process for the preparation thereof
ATE238300T1 (de) (3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl)-3-(1 - indol-3-yl)-alkylamine
ES471895A1 (es) Procedimiento para preparar derivados de benzamidina
MX9601953A (es) Nuevo compesto derivados de 5h-tiazolo [3,2-a] pirimidin-5-ona.