DK0791004T3 - Acylerede benzylglykosider som inhibitorer af glat-muskelceller-proliferation - Google Patents

Acylerede benzylglykosider som inhibitorer af glat-muskelceller-proliferation

Info

Publication number
DK0791004T3
DK0791004T3 DK95937706T DK95937706T DK0791004T3 DK 0791004 T3 DK0791004 T3 DK 0791004T3 DK 95937706 T DK95937706 T DK 95937706T DK 95937706 T DK95937706 T DK 95937706T DK 0791004 T3 DK0791004 T3 DK 0791004T3
Authority
DK
Denmark
Prior art keywords
carbon atoms
acyl group
phenylsulfonyl
cell proliferation
smooth muscle
Prior art date
Application number
DK95937706T
Other languages
English (en)
Inventor
Thomas T Nguyen
John Watson Ellingboe
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/531,142 external-priority patent/US5773420A/en
Application filed by American Home Prod filed Critical American Home Prod
Application granted granted Critical
Publication of DK0791004T3 publication Critical patent/DK0791004T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
DK95937706T 1994-11-07 1995-11-03 Acylerede benzylglykosider som inhibitorer af glat-muskelceller-proliferation DK0791004T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33528694A 1994-11-07 1994-11-07
US08/531,142 US5773420A (en) 1994-11-07 1995-10-20 Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation
PCT/US1995/014795 WO1996014325A1 (en) 1994-11-07 1995-11-03 Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation

Publications (1)

Publication Number Publication Date
DK0791004T3 true DK0791004T3 (da) 1999-11-29

Family

ID=26989635

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95937706T DK0791004T3 (da) 1994-11-07 1995-11-03 Acylerede benzylglykosider som inhibitorer af glat-muskelceller-proliferation

Country Status (16)

Country Link
EP (1) EP0791004B1 (da)
JP (1) JPH10508610A (da)
AT (1) ATE184283T1 (da)
AU (1) AU703338B2 (da)
BR (1) BR9509586A (da)
CA (1) CA2204530A1 (da)
DE (1) DE69512081T2 (da)
DK (1) DK0791004T3 (da)
ES (1) ES2136314T3 (da)
FI (1) FI971934A0 (da)
GR (1) GR3031731T3 (da)
HU (1) HUT77757A (da)
IL (1) IL115745A (da)
MX (1) MX9702966A (da)
NZ (1) NZ296037A (da)
WO (1) WO1996014325A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2351060A1 (en) * 1998-11-24 2000-06-15 Paul Jeffrey Dollings Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6340670B1 (en) 1998-11-24 2002-01-22 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en) 1998-11-24 2002-03-26 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
JP2002530424A (ja) * 1998-11-24 2002-09-17 アメリカン・ホーム・プロダクツ・コーポレイション 平滑筋細胞増殖の阻害薬としてのベンジルマルトシド
US6664243B1 (en) 1998-11-24 2003-12-16 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
AU3791200A (en) * 1998-11-24 2000-06-26 American Home Products Corporation Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US7081448B2 (en) 1998-11-24 2006-07-25 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
CN1333778A (zh) * 1998-11-24 2002-01-30 美国家用产品公司 用作平滑肌细胞增殖抑制剂的苄基麦芽三糖苷
AU5706699A (en) * 1998-11-24 2000-06-13 American Home Products Corporation Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6258784B1 (en) 1998-11-24 2001-07-10 American Home Products Corp. Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
JP2002530421A (ja) * 1998-11-24 2002-09-17 アメリカン・ホーム・プロダクツ・コーポレイション 平滑筋細胞増殖の阻害剤としてのアセタールベンジルマルトシド
US6451767B1 (en) 1998-11-24 2002-09-17 Wyeth Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en) 1998-11-24 2006-11-07 Wyeth Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6291434B1 (en) 1998-11-24 2001-09-18 American Home Products Corp. Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en) 1998-11-24 2002-01-15 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6187755B1 (en) 1998-11-24 2001-02-13 American Home Products Corporation Benzylmaltosides as inhibitors of smooth muscle cell proliferation
EP2124948B1 (en) 2007-02-21 2017-07-26 NC bit, Inc. Compositions for treating hyperproliferative vascular disorders and cancers
CN110152001B (zh) * 2019-05-20 2021-08-10 昆山德瑞生物科技有限公司 小分子化合物的用途及其组合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431637A (en) * 1982-10-25 1984-02-14 American Cyanamid Company Polycation salts of bis (or tris) [4-O-polyhexose-oxy]-arylene sulfate derivatives
FR2634485B1 (fr) * 1988-07-21 1992-02-28 Sanopi Glycosaminoglycanes selectivement o-acyles, leur preparation et compositions pharmaceutiques les contenant
US5032679A (en) * 1988-12-15 1991-07-16 Glycomed, Inc. Heparin fragments as inhibitors of smooth muscle cell proliferation
ES2060284T3 (es) * 1990-04-23 1994-11-16 Sanofi Elf Un procedimiento para la preparacion de un derivado de carbohidrato que comprende una unidad de trisacarido.

Also Published As

Publication number Publication date
GR3031731T3 (en) 2000-02-29
AU703338B2 (en) 1999-03-25
FI971934A (fi) 1997-05-06
ATE184283T1 (de) 1999-09-15
JPH10508610A (ja) 1998-08-25
FI971934A0 (fi) 1997-05-06
ES2136314T3 (es) 1999-11-16
EP0791004A1 (en) 1997-08-27
WO1996014325A1 (en) 1996-05-17
BR9509586A (pt) 1997-12-23
MX9702966A (es) 1997-06-28
AU3935395A (en) 1996-05-31
HUT77757A (hu) 1998-07-28
DE69512081D1 (de) 1999-10-14
NZ296037A (en) 1999-05-28
DE69512081T2 (de) 2000-02-03
IL115745A (en) 2000-11-21
IL115745A0 (en) 1996-01-19
EP0791004B1 (en) 1999-09-08
CA2204530A1 (en) 1996-05-17

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