GR3031731T3 - Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation - Google Patents

Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation

Info

Publication number
GR3031731T3
GR3031731T3 GR990402825T GR990402825T GR3031731T3 GR 3031731 T3 GR3031731 T3 GR 3031731T3 GR 990402825 T GR990402825 T GR 990402825T GR 990402825 T GR990402825 T GR 990402825T GR 3031731 T3 GR3031731 T3 GR 3031731T3
Authority
GR
Greece
Prior art keywords
carbon atoms
acyl group
phenylsulfonyl
cell proliferation
smooth muscle
Prior art date
Application number
GR990402825T
Other languages
English (en)
Inventor
Thomas T Nguyen
John Watson Ellingboe
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/531,142 external-priority patent/US5773420A/en
Application filed by American Home Prod filed Critical American Home Prod
Publication of GR3031731T3 publication Critical patent/GR3031731T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
GR990402825T 1994-11-07 1999-11-03 Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation GR3031731T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33528694A 1994-11-07 1994-11-07
US08/531,142 US5773420A (en) 1994-11-07 1995-10-20 Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation
PCT/US1995/014795 WO1996014325A1 (en) 1994-11-07 1995-11-03 Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation

Publications (1)

Publication Number Publication Date
GR3031731T3 true GR3031731T3 (en) 2000-02-29

Family

ID=26989635

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990402825T GR3031731T3 (en) 1994-11-07 1999-11-03 Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation

Country Status (16)

Country Link
EP (1) EP0791004B1 (el)
JP (1) JPH10508610A (el)
AT (1) ATE184283T1 (el)
AU (1) AU703338B2 (el)
BR (1) BR9509586A (el)
CA (1) CA2204530A1 (el)
DE (1) DE69512081T2 (el)
DK (1) DK0791004T3 (el)
ES (1) ES2136314T3 (el)
FI (1) FI971934A0 (el)
GR (1) GR3031731T3 (el)
HU (1) HUT77757A (el)
IL (1) IL115745A (el)
MX (1) MX9702966A (el)
NZ (1) NZ296037A (el)
WO (1) WO1996014325A1 (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187755B1 (en) 1998-11-24 2001-02-13 American Home Products Corporation Benzylmaltosides as inhibitors of smooth muscle cell proliferation
AU5706699A (en) * 1998-11-24 2000-06-13 American Home Products Corporation Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en) 1998-11-24 2006-11-07 Wyeth Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6664243B1 (en) 1998-11-24 2003-12-16 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
AU1743800A (en) * 1998-11-24 2000-06-26 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
EP1133512A2 (en) * 1998-11-24 2001-09-19 American Home Products Corporation Benzylmaltosides as inhibitors of smooth muscle cell proliferation
US7081448B2 (en) 1998-11-24 2006-07-25 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en) 1998-11-24 2002-03-26 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6451767B1 (en) 1998-11-24 2002-09-17 Wyeth Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6291434B1 (en) 1998-11-24 2001-09-18 American Home Products Corp. Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en) 1998-11-24 2002-01-15 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
BR9915643A (pt) * 1998-11-24 2001-08-07 American Home Prod Benzilmaltotriosìdeos como inibidores de proliferação de células do músculo liso
WO2000034295A2 (en) * 1998-11-24 2000-06-15 American Home Products Corporation Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6340670B1 (en) 1998-11-24 2002-01-22 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
WO2000031096A1 (en) * 1998-11-24 2000-06-02 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6258784B1 (en) 1998-11-24 2001-07-10 American Home Products Corp. Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
WO2008102932A1 (en) 2007-02-21 2008-08-28 Biobud Co., Ltd. Compositions for treating hyperproliferative vascular disorders and cancers
CN110152001B (zh) * 2019-05-20 2021-08-10 昆山德瑞生物科技有限公司 小分子化合物的用途及其组合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431637A (en) * 1982-10-25 1984-02-14 American Cyanamid Company Polycation salts of bis (or tris) [4-O-polyhexose-oxy]-arylene sulfate derivatives
FR2634485B1 (fr) * 1988-07-21 1992-02-28 Sanopi Glycosaminoglycanes selectivement o-acyles, leur preparation et compositions pharmaceutiques les contenant
US5032679A (en) * 1988-12-15 1991-07-16 Glycomed, Inc. Heparin fragments as inhibitors of smooth muscle cell proliferation
EP0454220B1 (en) * 1990-04-23 1993-08-18 Akzo Nobel N.V. Carbohydrate derivatives comprising a trisaccharide unit

Also Published As

Publication number Publication date
FI971934A (fi) 1997-05-06
AU3935395A (en) 1996-05-31
HUT77757A (hu) 1998-07-28
NZ296037A (en) 1999-05-28
IL115745A (en) 2000-11-21
AU703338B2 (en) 1999-03-25
DE69512081T2 (de) 2000-02-03
WO1996014325A1 (en) 1996-05-17
FI971934A0 (fi) 1997-05-06
EP0791004A1 (en) 1997-08-27
DE69512081D1 (de) 1999-10-14
ES2136314T3 (es) 1999-11-16
DK0791004T3 (da) 1999-11-29
ATE184283T1 (de) 1999-09-15
BR9509586A (pt) 1997-12-23
MX9702966A (es) 1997-06-28
CA2204530A1 (en) 1996-05-17
EP0791004B1 (en) 1999-09-08
JPH10508610A (ja) 1998-08-25
IL115745A0 (en) 1996-01-19

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