ZA959444B - Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation. - Google Patents

Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation.

Info

Publication number
ZA959444B
ZA959444B ZA9509444A ZA959444A ZA959444B ZA 959444 B ZA959444 B ZA 959444B ZA 9509444 A ZA9509444 A ZA 9509444A ZA 959444 A ZA959444 A ZA 959444A ZA 959444 B ZA959444 B ZA 959444B
Authority
ZA
South Africa
Prior art keywords
image
smooth muscle
cell proliferation
inhibitors
muscle cell
Prior art date
Application number
ZA9509444A
Other languages
English (en)
Inventor
Sarah T A Novak
John W Ellingboe
Richard M Soll
Thomas T Nguyen
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of ZA959444B publication Critical patent/ZA959444B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
ZA9509444A 1994-11-07 1995-11-07 Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation. ZA959444B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/335,278 US5498775A (en) 1994-11-07 1994-11-07 Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation

Publications (1)

Publication Number Publication Date
ZA959444B true ZA959444B (en) 1997-08-07

Family

ID=23311066

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9509444A ZA959444B (en) 1994-11-07 1995-11-07 Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation.

Country Status (18)

Country Link
US (1) US5498775A (xx)
EP (1) EP0791006B1 (xx)
JP (1) JPH10508606A (xx)
KR (1) KR970707139A (xx)
AT (1) ATE189227T1 (xx)
AU (1) AU702104B2 (xx)
BR (1) BR9509606A (xx)
DE (1) DE69514823T2 (xx)
DK (1) DK0791006T3 (xx)
ES (1) ES2141395T3 (xx)
FI (1) FI971935A0 (xx)
GR (1) GR3032629T3 (xx)
IL (1) IL115746A (xx)
MX (1) MX9703282A (xx)
NZ (1) NZ296828A (xx)
PT (1) PT791006E (xx)
WO (1) WO1996014323A1 (xx)
ZA (1) ZA959444B (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US5770609A (en) 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6306421B1 (en) 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5595722A (en) 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6663881B2 (en) 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
JPH11510479A (ja) 1995-06-07 1999-09-14 ネオルックス コーポレイション タモキシフェン類似体による心臓血管疾病の予防及び治療
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
PL185372B1 (pl) * 1995-06-29 2003-04-30 Texas Biotechnology Corp Inhibitory selektyny i kompozycja farmaceutyczna
US6001159A (en) * 1995-08-31 1999-12-14 Ricoh Company, Ltd. Reversible thermosensitive coloring composition and reversible thermosensitive recording medium using the same
US5919768A (en) * 1996-06-26 1999-07-06 Texas Biotechnology Corporation Di- and trivalent small molecule selectin inhibitors
US7081448B2 (en) * 1998-11-24 2006-07-25 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6291434B1 (en) 1998-11-24 2001-09-18 American Home Products Corp. Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en) 1998-11-24 2002-01-15 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
JP2003521460A (ja) * 1998-11-24 2003-07-15 ワイス 平滑筋細胞増殖の阻害薬としてのアセチル化ベンジルマルトシド
US6340670B1 (en) 1998-11-24 2002-01-22 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6187755B1 (en) 1998-11-24 2001-02-13 American Home Products Corporation Benzylmaltosides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en) * 1998-11-24 2006-11-07 Wyeth Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6664243B1 (en) 1998-11-24 2003-12-16 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6258784B1 (en) 1998-11-24 2001-07-10 American Home Products Corp. Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6451767B1 (en) 1998-11-24 2002-09-17 Wyeth Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en) 1998-11-24 2002-03-26 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
EP2124948B1 (en) 2007-02-21 2017-07-26 NC bit, Inc. Compositions for treating hyperproliferative vascular disorders and cancers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431636A (en) * 1982-05-24 1984-02-14 American Cyanamid Company Bis(4-O-polyhexaose-thio)-phenyl ureas and method of use
US4431637A (en) * 1982-10-25 1984-02-14 American Cyanamid Company Polycation salts of bis (or tris) [4-O-polyhexose-oxy]-arylene sulfate derivatives
US4435387A (en) * 1982-10-25 1984-03-06 American Cyanamid Company Poly-cation salts of bis (or tris) 4-O-polyhexose-thio-arylene sulfate derivatives
US4431638A (en) * 1982-10-25 1984-02-14 American Cyanamid Company Poly-cation salts of bis(or tris)[4-0-monohexose-thio]-arylene sulfate derivatives
DE3734815A1 (de) * 1987-10-14 1989-04-27 Luitpold Werk Chem Pharm Polyschwefelsaeureester von bis-aldonsaeureamiden und deren derivaten, verfahren zu ihrer herstellung und arzneimittel
DE3734853A1 (de) * 1987-10-14 1989-04-27 Luitpold Werk Chem Pharm Bis-aldonsaeureamide und verfahren zu ihrer herstellung
US5019562A (en) * 1988-01-19 1991-05-28 The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation Growth inhibiting agent and the use thereof
FR2634485B1 (fr) * 1988-07-21 1992-02-28 Sanopi Glycosaminoglycanes selectivement o-acyles, leur preparation et compositions pharmaceutiques les contenant
US5032679A (en) * 1988-12-15 1991-07-16 Glycomed, Inc. Heparin fragments as inhibitors of smooth muscle cell proliferation
ES2060284T3 (es) * 1990-04-23 1994-11-16 Sanofi Elf Un procedimiento para la preparacion de un derivado de carbohidrato que comprende una unidad de trisacarido.
AU678760B2 (en) * 1991-11-11 1997-06-12 Trustees Of The University Of Pennsylvania, The Methods of inhibiting restenosis

Also Published As

Publication number Publication date
AU702104B2 (en) 1999-02-11
US5498775A (en) 1996-03-12
FI971935A (fi) 1997-05-06
ATE189227T1 (de) 2000-02-15
DE69514823T2 (de) 2000-10-12
AU4154996A (en) 1996-05-31
EP0791006B1 (en) 2000-01-26
FI971935A0 (fi) 1997-05-06
DE69514823D1 (de) 2000-03-02
MX9703282A (es) 1997-08-30
IL115746A0 (en) 1996-01-19
IL115746A (en) 1999-11-30
PT791006E (pt) 2000-06-30
KR970707139A (ko) 1997-12-01
DK0791006T3 (da) 2000-04-17
EP0791006A2 (en) 1997-08-27
ES2141395T3 (es) 2000-03-16
GR3032629T3 (en) 2000-05-31
JPH10508606A (ja) 1998-08-25
NZ296828A (en) 1999-04-29
BR9509606A (pt) 1997-10-28
WO1996014323A1 (en) 1996-05-17

Similar Documents

Publication Publication Date Title
GR3032629T3 (en) Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation
AU528275B2 (en) Imidazole derivatives
ZA959436B (en) Smooth muscle cell proliferation inhibitors.
AU8686991A (en) New 3-cycloalkyl-propanamides, their tautomer forms and their salts, preparation process, use as medicaments and compositions containing them
IL115745A (en) Acylated benzylglycosides and pharmaceutical compositions containing them
ES483289A1 (es) Un procedimiento para la preparacion de 1,2,3,5, tetrahidro-himidazotienopirimidin-2-onas.
CA2204204A1 (en) Carbohydrate derivatives
AU2406700A (en) 3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl(3-(1h-indol-3-yl)-a kyl)-amines
MX9601953A (es) Nuevo compesto derivados de 5h-tiazolo [3,2-a] pirimidin-5-ona.