MXPA05011125A - Remedio preventivo para enfermedades del nervio retiniano que contienen derivados de eter de alquilo o sales de los mismos. - Google Patents
Remedio preventivo para enfermedades del nervio retiniano que contienen derivados de eter de alquilo o sales de los mismos.Info
- Publication number
- MXPA05011125A MXPA05011125A MXPA05011125A MXPA05011125A MXPA05011125A MX PA05011125 A MXPA05011125 A MX PA05011125A MX PA05011125 A MXPA05011125 A MX PA05011125A MX PA05011125 A MXPA05011125 A MX PA05011125A MX PA05011125 A MXPA05011125 A MX PA05011125A
- Authority
- MX
- Mexico
- Prior art keywords
- remedy
- preventive
- alkyl ether
- retinal nerve
- retinal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrrole Compounds (AREA)
Abstract
Un derivado de eter de alquilo representado por la formula general (I) (ver formula I): o su sal: en donde R1 y R2 representan cada uno un sustituyente como hidrogeno, halogeno, o alquilo; R3 representa alquilamino, amino o hidroxilo; el anillo A representa un heterociclo aromatico de 5 o 6 miembros o un anillo de benceno; m y n son cada uno un numero entero de 1 a 6; y p es un numero entero de 1 a 3; muestra un efecto de proteccion de las celulas del nervio retiniano y, por lo tanto, es util como un tratamiento preventivo y/o remedio para enfermedades del nervio retiniano como glaucoma, retinopatia diabetica, obstruccion arterial retiniana, obstruccion venosa retiniana, degeneracion macular y retinopatia de premadurez.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003112539 | 2003-04-17 | ||
PCT/JP2004/005355 WO2004091605A1 (ja) | 2003-04-17 | 2004-04-15 | アルキルエーテル誘導体またはその塩を含有する網膜神経疾患の予防・治療剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05011125A true MXPA05011125A (es) | 2005-12-14 |
Family
ID=33296058
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05011125A MXPA05011125A (es) | 2003-04-17 | 2004-04-15 | Remedio preventivo para enfermedades del nervio retiniano que contienen derivados de eter de alquilo o sales de los mismos. |
Country Status (20)
Country | Link |
---|---|
US (3) | US20060205709A1 (es) |
EP (1) | EP1614419B1 (es) |
JP (1) | JP4642657B2 (es) |
KR (1) | KR101096528B1 (es) |
CN (1) | CN100353942C (es) |
AU (1) | AU2004229283B2 (es) |
BR (1) | BRPI0409398A (es) |
CA (1) | CA2521648C (es) |
CY (1) | CY1113248T1 (es) |
DK (1) | DK1614419T3 (es) |
ES (1) | ES2391273T3 (es) |
IL (1) | IL171388A (es) |
MX (1) | MXPA05011125A (es) |
NO (1) | NO334062B1 (es) |
NZ (1) | NZ543100A (es) |
PL (1) | PL1614419T3 (es) |
PT (1) | PT1614419E (es) |
SI (1) | SI1614419T1 (es) |
WO (1) | WO2004091605A1 (es) |
ZA (1) | ZA200508166B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL215264B1 (pl) * | 2001-10-19 | 2013-11-29 | Toyama Chemical Co Ltd | Pochodne eteru alkilowego lub ich sole, sposób ich wytwarzania oraz kompozycja farmaceutyczna |
SI2389937T1 (sl) | 2002-06-14 | 2018-10-30 | Toyama Chemical Co., Ltd, | Farmacevtska sestava za izboljšanje možganske funkcije |
SI2348022T1 (sl) | 2005-03-28 | 2013-05-31 | Toyama Chemical Co., Ltd. | Postopek proizvodnje 1-(3-(2-(1-benzotiofen-5-il)etoksi)propil)azetidin-3-ola ali soli le-tega |
US8119625B2 (en) | 2006-04-26 | 2012-02-21 | Toyama Chemical Co., Ltd. | Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof |
WO2007125913A1 (ja) * | 2006-04-26 | 2007-11-08 | Toyama Chemical Co., Ltd. | アルキルエーテル誘導体またはその塩を含有する神経細胞新生誘導剤および精神障害治療剤 |
JP5255441B2 (ja) * | 2006-08-04 | 2013-08-07 | 富山化学工業株式会社 | アルキルエーテル誘導体またはその塩を含有するプロテインキナーゼc活性促進剤 |
PT2300514E (pt) | 2008-07-14 | 2016-06-20 | Biocon Ltd | Um método de síntese de uma mistura substancialmente monodispersa de oligómeros |
PL2818165T3 (pl) * | 2012-02-22 | 2019-09-30 | Fujifilm Toyama Chemical Co., Ltd. | Stała kompozycja farmaceutyczna zawierająca 1-(3-(2-(1-benzotiofen-5-ylo)etoksy)propylo)-azetydyn-3-ol albo jego sól |
SG10201907035TA (en) * | 2014-01-31 | 2019-09-27 | Fujifilm Toyama Chemical Co Ltd | Post nerve injury rehabilitation effect-enhancing agent comprising alkyl ether derivative or salt thereof |
US10238632B2 (en) | 2015-06-11 | 2019-03-26 | Fujifilm Toyama Chemical Co., Ltd. | Sigma receptor-binding agent |
US11304928B2 (en) | 2015-12-25 | 2022-04-19 | Fujifilm Toyama Chemical Co., Ltd. | Tablet comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salt thereof |
US20190343796A1 (en) | 2016-12-28 | 2019-11-14 | Fujifilm Toyama Chemical Co., Ltd. | Composition for external use |
BR112019024851A2 (pt) | 2017-06-02 | 2020-06-09 | Fujifilm Toyama Chemical Co Ltd | agente para evitar ou tratar atrofia cerebral |
EP3636262A4 (en) | 2017-06-02 | 2020-06-10 | FUJIFILM Toyama Chemical Co., Ltd. | AGENT FOR PREVENTING OR TREATING ALZHEIMER-LIKE DEMENTIA |
IL270910B2 (en) | 2017-06-02 | 2024-03-01 | Fujifilm Toyama Chemical Co Ltd | 1-(3-(2-(1-benzothiophene-5-yl)ethoxy)propyl)aztidine-3-ol or a salt thereof for use in suppressing cerebral atrophy |
RU2019138538A (ru) | 2017-06-02 | 2021-07-09 | ФУДЖИФИЛМ Тояма Кемикал Ко., Лтд. | СРЕДСТВО ДЛЯ УМЕНЬШЕНИЯ КОЛИЧЕСТВА АМИЛОИДНОГО β-БЕЛКА |
EP3705121B1 (en) | 2017-10-30 | 2023-08-30 | FUJIFILM Toyama Chemical Co., Ltd. | Emopamil binding protein binding agent and use thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2521136A1 (fr) * | 1982-02-05 | 1983-08-12 | Synthelabo | Derives de piperidine, leur preparation et leur application en therapeutique |
US5922773A (en) | 1992-12-04 | 1999-07-13 | The Children's Medical Center Corp. | Glaucoma treatment |
DK74693D0 (da) | 1993-06-23 | 1993-06-23 | Novo Nordisk As | Novel heterocyclic chemistry |
TW281667B (es) * | 1994-02-03 | 1996-07-21 | Synthelabo | |
EP0873990A1 (en) | 1995-09-22 | 1998-10-28 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzoic acid compounds and medicinal use thereof |
JP4549452B2 (ja) * | 1997-12-12 | 2010-09-22 | 富山化学工業株式会社 | アルキルエーテル誘導体またはその塩並びにそれらを含有するカルシウム拮抗剤 |
JPWO2002030420A1 (ja) * | 2000-10-10 | 2004-02-19 | 富山化学工業株式会社 | 1,2−エタンジオール誘導体またはその塩を含有する網膜神経疾患治療剤 |
JPWO2002100833A1 (ja) * | 2001-06-12 | 2004-09-24 | 住友製薬株式会社 | Rhoキナーゼ阻害剤 |
PL215264B1 (pl) * | 2001-10-19 | 2013-11-29 | Toyama Chemical Co Ltd | Pochodne eteru alkilowego lub ich sole, sposób ich wytwarzania oraz kompozycja farmaceutyczna |
SI2389937T1 (sl) * | 2002-06-14 | 2018-10-30 | Toyama Chemical Co., Ltd, | Farmacevtska sestava za izboljšanje možganske funkcije |
-
2004
- 2004-04-15 KR KR1020057019794A patent/KR101096528B1/ko not_active IP Right Cessation
- 2004-04-15 NZ NZ543100A patent/NZ543100A/en unknown
- 2004-04-15 CN CNB2004800103801A patent/CN100353942C/zh not_active Expired - Fee Related
- 2004-04-15 PL PL04727697T patent/PL1614419T3/pl unknown
- 2004-04-15 PT PT04727697T patent/PT1614419E/pt unknown
- 2004-04-15 JP JP2005505437A patent/JP4642657B2/ja not_active Expired - Fee Related
- 2004-04-15 ZA ZA200508166A patent/ZA200508166B/en unknown
- 2004-04-15 AU AU2004229283A patent/AU2004229283B2/en not_active Ceased
- 2004-04-15 EP EP04727697A patent/EP1614419B1/en not_active Expired - Lifetime
- 2004-04-15 DK DK04727697.7T patent/DK1614419T3/da active
- 2004-04-15 CA CA2521648A patent/CA2521648C/en not_active Expired - Fee Related
- 2004-04-15 WO PCT/JP2004/005355 patent/WO2004091605A1/ja active Application Filing
- 2004-04-15 ES ES04727697T patent/ES2391273T3/es not_active Expired - Lifetime
- 2004-04-15 BR BRPI0409398-4A patent/BRPI0409398A/pt not_active Application Discontinuation
- 2004-04-15 US US10/553,120 patent/US20060205709A1/en not_active Abandoned
- 2004-04-15 SI SI200431955T patent/SI1614419T1/sl unknown
- 2004-04-15 MX MXPA05011125A patent/MXPA05011125A/es unknown
-
2005
- 2005-10-11 IL IL171388A patent/IL171388A/en not_active IP Right Cessation
- 2005-10-20 NO NO20054855A patent/NO334062B1/no not_active IP Right Cessation
-
2009
- 2009-08-17 US US12/542,074 patent/US7897594B2/en not_active Expired - Fee Related
-
2011
- 2011-01-19 US US13/008,982 patent/US8067406B2/en not_active Expired - Fee Related
-
2012
- 2012-10-23 CY CY20121100992T patent/CY1113248T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
IL171388A (en) | 2010-12-30 |
KR101096528B1 (ko) | 2011-12-20 |
CN100353942C (zh) | 2007-12-12 |
JPWO2004091605A1 (ja) | 2006-07-06 |
ZA200508166B (en) | 2007-03-28 |
US8067406B2 (en) | 2011-11-29 |
US20110112066A1 (en) | 2011-05-12 |
PL1614419T3 (pl) | 2013-01-31 |
NO20054855D0 (no) | 2005-10-20 |
PT1614419E (pt) | 2012-10-22 |
NO334062B1 (no) | 2013-12-02 |
EP1614419A4 (en) | 2010-08-18 |
CY1113248T1 (el) | 2016-04-13 |
WO2004091605A1 (ja) | 2004-10-28 |
CN1774245A (zh) | 2006-05-17 |
NZ543100A (en) | 2008-07-31 |
ES2391273T3 (es) | 2012-11-23 |
CA2521648A1 (en) | 2004-10-28 |
AU2004229283B2 (en) | 2009-02-05 |
NO20054855L (no) | 2006-01-09 |
CA2521648C (en) | 2012-07-03 |
US20100075941A1 (en) | 2010-03-25 |
AU2004229283A1 (en) | 2004-10-28 |
KR20050123167A (ko) | 2005-12-29 |
SI1614419T1 (sl) | 2012-12-31 |
JP4642657B2 (ja) | 2011-03-02 |
EP1614419B1 (en) | 2012-08-08 |
EP1614419A1 (en) | 2006-01-11 |
BRPI0409398A (pt) | 2006-04-18 |
US7897594B2 (en) | 2011-03-01 |
US20060205709A1 (en) | 2006-09-14 |
DK1614419T3 (da) | 2012-11-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20054855L (no) | Preventiv/hjelpemiddel for retinal nervesykdommer inneholdende alkyleterderivater eller salter derav | |
TW200617001A (en) | Novel glucitol derivative, its prodrug, their salt and diabetic therapeutic agent containing the same | |
NO20041531L (no) | Alkyleterderivater eller salter derav | |
MY107740A (en) | Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof | |
AR038419A1 (es) | Derivados de piridina y quinolina | |
WO2003011880A1 (fr) | Derive de glucopyranosyloxybenzylbenzene, composition medicinale contenant ce derive, usage medicinal de cette composition et produit intermediaire pour produire cette composition | |
HUP0203190A2 (hu) | Glükopiranoziloxi-pirazol-származékok, az ezeket tartalmazó gyógyászati készítmények, valamint az ezek előállításához használható köztitermékek | |
AU692090B2 (en) | Novel 4,6-diarylpyrimidine derivatives and salts thereof | |
EP1396493A4 (en) | HETEROCYCLIC COMPOUNDS | |
EA200601235A1 (ru) | Производные тиазола | |
HUP0400527A2 (hu) | Benzoil-piridin-származékok vagy sóik, ezeket aktív alkotórészként tartalmazó fungicidek, eljárás ezek előállítására, és köztes termékek ezek előállításához | |
BRPI0408189A (pt) | 8'-piridinil-dihidroespiro-[cicloalquil]-pirimido[1,2-a]p irimidin-6-ona substituìda e derivados de 8'-pirimidinil-dihidroespiro-[cicloalquil]-pirimido[1,2- a]pirimidin-6-ona e seus usos contra doenças neurodegenerativas | |
NO20045483L (no) | Bedring av utviklingen av katarakt og andre oftalmiske sykdommer | |
NO20075409L (no) | Substituerte aminoalkyl- og amidoalkyl-benzopyranderivater | |
WO2009041566A1 (ja) | キナゾリノン誘導体又はキノキサリン誘導体を有効成分として含有する後眼部疾患の予防又は治療剤 | |
MX2009004884A (es) | Derivados 8-piperidinil-2-piridinil-pirimido [1,2-a] pirimidin-6-ona y 8-piperidinil-2-pirimidinil-pirimido [1,2-a] pirimidin-6-ona sustuidos. | |
AU4396899A (en) | Remedies for diabetes | |
RU2007141887A (ru) | Защитное средство для нейронных клеток сетчатки, содержащее в качестве активного ингредиента производные индазола | |
EP1602647A4 (en) | NOVEL COMPOUND COMPRISING A 4-PYRIDYLALKYLTHIO GROUP AS SUBSTITUTE | |
EA200901402A1 (ru) | Терапевтическое средство против глаукомы, содержащее в качестве активного ингредиента производное аденозина | |
HK1061674A1 (en) | 5-amidino-2-hydroxybenzenesulfonamide derivatives, pharmaceutical compositions containing the same and intermediates for their preparation | |
NO20004405L (no) | Farmasøytisk sammensetning for profylakse og terapi av sykdommer forbundet med okulær-fundus-vev cytopati | |
NO942756L (no) | Behandling av glaucoma | |
MX2010002475A (es) | Derivados de alquilsulfona. | |
NO941932D0 (no) | Nye [1-(1H-imidazol-4-yl)-alkylÅ-benzenderivater, fremgangsmåte ved deres fremstilling og öyepreparater inneholdende dem som aktiv bestanddel |