NO20044481L - Azabisykliske, azatrisykliske og azaspirosykliske derivater av aminosykloheksan-NMDA, -5HT3 og neuronale nikotinreseptorantagonister. - Google Patents

Azabisykliske, azatrisykliske og azaspirosykliske derivater av aminosykloheksan-NMDA, -5HT3 og neuronale nikotinreseptorantagonister.

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Publication number
NO20044481L
NO20044481L NO20044481A NO20044481A NO20044481L NO 20044481 L NO20044481 L NO 20044481L NO 20044481 A NO20044481 A NO 20044481A NO 20044481 A NO20044481 A NO 20044481A NO 20044481 L NO20044481 L NO 20044481L
Authority
NO
Norway
Prior art keywords
azabicyclic
nmda
receptor antagonists
azatrocyclic
nicotine receptor
Prior art date
Application number
NO20044481A
Other languages
English (en)
Norwegian (no)
Inventor
Wojciech Danysz
Markus Gold
Ivars Kalvinsh
Valerjans Kauss
Aigars Jirgensons
Christopher Graham Raphael Parsons
Markus Henrich
Maksims Vanejevs
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of NO20044481L publication Critical patent/NO20044481L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • C—CHEMISTRY; METALLURGY
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    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Addiction (AREA)
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  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Otolaryngology (AREA)
  • AIDS & HIV (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20044481A 2002-03-21 2004-10-20 Azabisykliske, azatrisykliske og azaspirosykliske derivater av aminosykloheksan-NMDA, -5HT3 og neuronale nikotinreseptorantagonister. NO20044481L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36638602P 2002-03-21 2002-03-21
PCT/GB2003/001236 WO2003080046A1 (en) 2002-03-21 2003-03-21 Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane nmda, 5ht3, and neuronal nicotinic receptor antagoni sts

Publications (1)

Publication Number Publication Date
NO20044481L true NO20044481L (no) 2004-10-20

Family

ID=28454794

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20044481A NO20044481L (no) 2002-03-21 2004-10-20 Azabisykliske, azatrisykliske og azaspirosykliske derivater av aminosykloheksan-NMDA, -5HT3 og neuronale nikotinreseptorantagonister.

Country Status (19)

Country Link
US (4) US7022729B2 (ru)
EP (1) EP1485086A1 (ru)
JP (1) JP4262606B2 (ru)
KR (1) KR100741257B1 (ru)
CN (1) CN1638762A (ru)
AR (1) AR039008A1 (ru)
AU (1) AU2003216855B2 (ru)
CA (1) CA2474637A1 (ru)
CO (1) CO5611104A2 (ru)
EA (1) EA007098B1 (ru)
GE (1) GEP20063954B (ru)
IL (1) IL164041A0 (ru)
MX (1) MXPA04007755A (ru)
NO (1) NO20044481L (ru)
PL (1) PL372701A1 (ru)
TW (1) TW200306189A (ru)
UA (1) UA77778C2 (ru)
WO (1) WO2003080046A1 (ru)
ZA (1) ZA200406940B (ru)

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US20060205822A1 (en) * 2004-12-22 2006-09-14 Forest Laboratories, Inc. 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect
EP2111858A1 (en) 2008-04-25 2009-10-28 EPFL Ecole Polytechnique Fédérale de Lausanne Novel treatment for alzheimer's disease
US20090275597A1 (en) * 2008-05-02 2009-11-05 Forest Laboratories Holdings Limited Methods of treating cns disorders
WO2011149862A1 (en) 2010-05-27 2011-12-01 Targacept, Inc. Nicotinic receptor non-competitive antagonists modulators
BR112014010719A2 (pt) * 2011-11-03 2017-05-02 Targacept Inc moduladores não competitivos de receptor nicotínico
WO2013111799A1 (ja) 2012-01-25 2013-08-01 国立大学法人東北大学 脳機能改善剤
TW201522307A (zh) 2013-03-14 2015-06-16 百靈佳殷格翰國際股份有限公司 經取代２－氮雜－雙環［２．２．１］庚烷－３－羧酸（苄基－氰基－甲基）－醯胺組織蛋白酶ｃ抑制劑
BR112017003433B1 (pt) 2014-09-12 2023-11-14 Boehringer Ingelheim International Gmbh Inibidores espirocíclicos de catepsina c, composição farmacêutica e uso dos mesmos

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IL164041A0 (en) 2005-12-18
GEP20063954B (en) 2006-10-25
AR039008A1 (es) 2005-02-02
CN1638762A (zh) 2005-07-13
UA77778C2 (en) 2007-01-15
AU2003216855B2 (en) 2005-08-18
US7022729B2 (en) 2006-04-04
EP1485086A1 (en) 2004-12-15
KR100741257B1 (ko) 2007-07-19
TW200306189A (en) 2003-11-16
US20060019983A1 (en) 2006-01-26
MXPA04007755A (es) 2004-10-15
ZA200406940B (en) 2005-09-22
CO5611104A2 (es) 2006-02-28
KR20040091005A (ko) 2004-10-27
US20060019982A1 (en) 2006-01-26
EA007098B1 (ru) 2006-06-30
JP2005525385A (ja) 2005-08-25
US7238703B2 (en) 2007-07-03
US20040034055A1 (en) 2004-02-19
US20070185151A1 (en) 2007-08-09
PL372701A1 (en) 2005-07-25
WO2003080046A1 (en) 2003-10-02
AU2003216855A1 (en) 2003-10-08
CA2474637A1 (en) 2003-10-02
EA200401230A1 (ru) 2005-02-24
JP4262606B2 (ja) 2009-05-13

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