NO20044341L - Isostrukturelle pseudopolymorfer av 9-deokso-9a-aza-9a-metyl-9a-homoerytromycin - Google Patents

Isostrukturelle pseudopolymorfer av 9-deokso-9a-aza-9a-metyl-9a-homoerytromycin

Info

Publication number
NO20044341L
NO20044341L NO20044341A NO20044341A NO20044341L NO 20044341 L NO20044341 L NO 20044341L NO 20044341 A NO20044341 A NO 20044341A NO 20044341 A NO20044341 A NO 20044341A NO 20044341 L NO20044341 L NO 20044341L
Authority
NO
Norway
Prior art keywords
homoerythromycin
deoxo
aza
methyl
pseudopolymorph
Prior art date
Application number
NO20044341A
Other languages
English (en)
Norwegian (no)
Inventor
Mladen Vinkovic
Mikjenko Dumic
Original Assignee
Pliva Istrazivacki Inst Doo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Istrazivacki Inst Doo filed Critical Pliva Istrazivacki Inst Doo
Publication of NO20044341L publication Critical patent/NO20044341L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thermal Transfer Or Thermal Recording In General (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Finger-Pressure Massage (AREA)
  • Instructional Devices (AREA)
NO20044341A 2002-03-18 2004-10-13 Isostrukturelle pseudopolymorfer av 9-deokso-9a-aza-9a-metyl-9a-homoerytromycin NO20044341L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
HR20020231A HRP20020231A2 (en) 2002-03-18 2002-03-18 ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
US39361202P 2002-07-03 2002-07-03
US39470502P 2002-07-08 2002-07-08
PCT/IB2003/000987 WO2003077830A2 (en) 2002-03-18 2003-03-18 9-dexo-9a-aza-9a-methyl-9a-homoerythromycin a derivatives

Publications (1)

Publication Number Publication Date
NO20044341L true NO20044341L (no) 2004-11-23

Family

ID=28045976

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20044341A NO20044341L (no) 2002-03-18 2004-10-13 Isostrukturelle pseudopolymorfer av 9-deokso-9a-aza-9a-metyl-9a-homoerytromycin

Country Status (23)

Country Link
US (1) US7569549B2 (zh)
EP (2) EP1485393B1 (zh)
JP (1) JP2005529082A (zh)
KR (1) KR20050002872A (zh)
CN (1) CN1642966A (zh)
AT (1) ATE440104T1 (zh)
AU (1) AU2003215779A1 (zh)
BG (1) BG108874A (zh)
BR (1) BR0308644A (zh)
CA (1) CA2479211A1 (zh)
DE (1) DE60328872D1 (zh)
EA (1) EA200401217A1 (zh)
ES (1) ES2331733T3 (zh)
HR (2) HRP20020231A2 (zh)
IL (1) IL163836A0 (zh)
IS (1) IS7449A (zh)
MX (1) MXPA04009009A (zh)
NO (1) NO20044341L (zh)
NZ (1) NZ535477A (zh)
PL (1) PL372468A1 (zh)
RS (1) RS82504A (zh)
TN (1) TNSN04166A1 (zh)
WO (1) WO2003077830A2 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20020231A2 (en) 2002-03-18 2003-12-31 Pliva D D ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
HRP20020614A2 (en) * 2002-07-22 2004-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a
DE602004019288D1 (de) 2003-07-24 2009-03-19 Pliva Hrvatska D O O Schnellösliches azithromycin in einzeldosisform
EP1878432A1 (en) * 2003-07-24 2008-01-16 Pliva - Research and Development Ltd. Single dose fast dissolving azithromycin
BRPI0417338A (pt) * 2003-12-04 2007-04-17 Pfizer Prod Inc formas de dosagem de azitromicina multiparticulada por processos a base de lìquido
PT1691787E (pt) * 2003-12-04 2008-09-02 Pfizer Prod Inc Método de formação de multipartículas farmacêuticas
BRPI0417348A (pt) * 2003-12-04 2007-03-13 Pfizer Prod Inc processo de gelatinização por spray com utilização de uma extrusora para preparação de composições de droga cristalina multiparticulada contendo preferencialmente um poloxámero e um glicerìdeo
BRPI0416534A (pt) 2003-12-04 2007-01-09 Pfizer Prod Inc composições multiparticuladas com estabilidade melhorada
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI8110592A8 (en) 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
RO107257B1 (ro) * 1987-07-09 1993-10-30 Pfizer Procedeu de obtinere a unui dihidrat de azitromicina, cristalin
HRP20020231A2 (en) 2002-03-18 2003-12-31 Pliva D D ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
WO1994026758A1 (en) 1993-05-19 1994-11-24 Pfizer Inc. Intermediate for azithromycin
HRP940251B1 (en) 1994-04-15 1998-12-31 Stjepan Mutak Process for the preparation of azithromycin dihydrochloride
ES2122905B1 (es) * 1996-07-11 1999-11-16 Astur Pharma Sa Sintesis de 11,12-hidrogenoortoborato de 9-desoxo-9a-aza-11,12-desoxi-9a-metil-9a-homoeritromicina a. un procedimiento para la preparacion de 9-desoxo-9a-aza-9a-metil-9a-homoeritromicina a dihidrato (azitromicina dihidrato).
PT102130A (pt) 1998-03-13 1999-09-30 Hovione Sociedade Quimica S A Processo de preparacao de dihidrato de azitromicina
CN1205338A (zh) 1998-05-08 1999-01-20 刘万忠 阿奇霉素水溶性盐的合成新方法及其在医药上的用途
TW546302B (en) * 1998-05-08 2003-08-11 Biochemie Sa Improvements in macrolide production
CA2245398C (en) 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
US6365574B2 (en) * 1998-11-30 2002-04-02 Teva Pharmaceutical Industries Ltd. Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof
US6703372B1 (en) * 1999-06-29 2004-03-09 Biochemie S.A. Macrolides
ES2177373B1 (es) * 1999-11-26 2003-11-01 Astur Pharma Sa Preparacion de azitromicina en su forma no cristalina
WO2001049697A1 (en) * 2000-01-04 2001-07-12 Teva Pharmaceutical Industries Ltd. Preparation method of azithromycin dihydrate
ES2162764B1 (es) * 2000-05-17 2003-04-01 Ercros Ind Sa Forma polimorfica del dihidrato de azitromicina, y su procedimiento deobtencion.
CA2417353C (en) * 2000-07-25 2009-09-01 Laboratorio Silanes,S.A. De C.V. Single-step process for preparing 7,16-deoxy-2-aza-10-o-cladinosil-12-o-desosaminil-4,5-dihydroxi-6-ethyl-3,5,9,11,13,15-hexamethylbicycle (11.2.1)hexadeca-1(2)-en-8-one, and obtaining a new form of 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin a
AU2001280000A1 (en) 2000-08-23 2002-03-04 Jaweed Mukarram, Siddiqui Mohammed Process for preparation of anhydrous azithromycin
WO2002042315A2 (en) * 2000-11-27 2002-05-30 Biochemie S.A. Macrolide solvates
KR100491183B1 (ko) 2001-03-21 2005-05-25 한미약품 주식회사 아지트로마이신의 제조방법 및 이 방법에 사용되는9-데옥소-9에이-아자-9에이-호모에리트로마이신 에이의결정성 수화물
KR100431431B1 (ko) 2001-04-25 2004-05-14 한미약품 주식회사 아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물
HRP20010301A2 (en) 2001-04-27 2001-12-31 Pliva D D New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases
MXPA03010028A (es) 2001-05-22 2004-02-12 Pfizer Prod Inc Formas cristalinas de azitromicina.
US6861413B2 (en) 2001-05-22 2005-03-01 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
MXPA04005105A (es) 2001-12-21 2004-08-19 Pfizer Prod Inc Formulaciones de acitromicina directamente compresibles.
EP1455757A2 (en) 2001-12-21 2004-09-15 Pfizer Products Inc. Methods for wet granulating azithromycin
JP2005526020A (ja) 2002-02-01 2005-09-02 ファイザー・プロダクツ・インク アジスロマイシンの乾式造粒配合物
ITMI20021209A1 (it) 2002-06-04 2003-12-04 Chemi Spa Processo di preparazione di azitromicina ad elevata purezza

Also Published As

Publication number Publication date
AU2003215779A1 (en) 2003-09-29
US20040014951A1 (en) 2004-01-22
PL372468A1 (en) 2005-07-25
ATE440104T1 (de) 2009-09-15
BG108874A (en) 2005-12-30
MXPA04009009A (es) 2005-06-17
CN1642966A (zh) 2005-07-20
WO2003077830A2 (en) 2003-09-25
IS7449A (is) 2004-09-16
KR20050002872A (ko) 2005-01-10
BR0308644A (pt) 2005-01-25
IL163836A0 (en) 2005-12-18
EP1627883A1 (en) 2006-02-22
WO2003077830A3 (en) 2004-05-13
HRP20040858A2 (en) 2005-06-30
DE60328872D1 (en) 2009-10-01
TNSN04166A1 (en) 2007-03-12
JP2005529082A (ja) 2005-09-29
EP1485393B1 (en) 2009-08-19
HRP20020231A2 (en) 2003-12-31
CA2479211A1 (en) 2003-09-25
EP1485393A2 (en) 2004-12-15
US7569549B2 (en) 2009-08-04
NZ535477A (en) 2006-11-30
ES2331733T3 (es) 2010-01-14
RS82504A (en) 2006-12-15
EA200401217A1 (ru) 2005-02-24

Similar Documents

Publication Publication Date Title
NO20044341L (no) Isostrukturelle pseudopolymorfer av 9-deokso-9a-aza-9a-metyl-9a-homoerytromycin
WO2003097598A8 (fr) Composé comprenant un antagonisme du récepteur de pdg2
DK1558579T3 (da) N-alkyl-4-methylenamino-3-hydroxy-2-pyridoner som antimikrobialer
MXPA03008755A (es) Derivados de 2-amino-propanol.
NO2012012I2 (no) Pasireotide (som diaspartat salt). Det kjemiske navnet er cyclo[(4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L-phenylalanyl-)
NO20062292L (no) Fremgangsmate for behandling av transplantasjonsavstoting
BR0014274A (pt) Composições de intercalação de catodo, métodos de produção e baterias de lìtio recarregáveis contendo as mesmas
NO20044534L (no) Substituerte fenylacetamider og deres anvendelse som glukokinaseaktivatorer
CA2391659A1 (en) Crystal forms of azithromycin
NO20034661L (no) Nociceptin-analoger
CY1110000T1 (el) Ενωσεις οκταϋδροβενζιμιδαζολονης ως αναλγητικα
EP1457550A3 (en) Composition for removing residues from the microstructure of an object
ATE403429T1 (de) Spiropyrazol-verbindungen
NO20062629L (no) Oksazolderivater av tetrackliner
ATE274913T1 (de) Wässerige zusammensetzung enthaltend amphotericin b
BR0111780A (pt) Agente herbicida
DE69725696D1 (de) Carbapenem-antibiotikum, zusammensetzung und ihre herstellung
MXPA03009602A (es) Analogos de nociceptina.
WO2003053971A8 (en) Pyridoquinoxaline antivirals
TR200001950T2 (tr) İkameli 2-benzilamino-2-fenil-asetamid bileşikler.
DE60015390D1 (de) Antidiabetische thiazolidindione und ihre herstellung
CA2336129A1 (en) Ectoparasiticide agents
TW200609228A (en) Substituted n-acyl-2-aminothiazoles
BR0109946A (pt) Derivados de eritromicina substituìda em 6-o tendo tolerância gastrointestinal
PT1204659E (pt) Benzofuranos serotoninergicos