NO20035791L - Nye derivater av oksazolidinoner som antibakterielle midler - Google Patents
Nye derivater av oksazolidinoner som antibakterielle midlerInfo
- Publication number
- NO20035791L NO20035791L NO20035791A NO20035791A NO20035791L NO 20035791 L NO20035791 L NO 20035791L NO 20035791 A NO20035791 A NO 20035791A NO 20035791 A NO20035791 A NO 20035791A NO 20035791 L NO20035791 L NO 20035791L
- Authority
- NO
- Norway
- Prior art keywords
- oxazolidinones
- antibacterial agents
- new derivatives
- derivatives
- medicament
- Prior art date
Links
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical class O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003242 anti bacterial agent Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940124307 fluoroquinolone Drugs 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200101559A ES2186550B2 (es) | 2001-06-27 | 2001-06-27 | Nuevos derivados de oxazolidinonas como antibacterianos. |
| PCT/IB2002/002408 WO2003002560A1 (en) | 2001-06-27 | 2002-06-24 | New derivatives of oxazolidinones as antibacterial agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20035791L true NO20035791L (no) | 2004-02-19 |
Family
ID=8498288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20035791A NO20035791L (no) | 2001-06-27 | 2003-12-22 | Nye derivater av oksazolidinoner som antibakterielle midler |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US20040147545A1 (es) |
| EP (1) | EP1401834A1 (es) |
| JP (1) | JP2004521147A (es) |
| KR (1) | KR20040030712A (es) |
| CN (1) | CN1520412A (es) |
| AP (1) | AP2003002942A0 (es) |
| AR (1) | AR035254A1 (es) |
| BG (1) | BG108498A (es) |
| BR (1) | BR0210667A (es) |
| CA (1) | CA2450982A1 (es) |
| CO (1) | CO5540387A2 (es) |
| CR (1) | CR7195A (es) |
| CZ (1) | CZ2004101A3 (es) |
| EA (1) | EA200400086A1 (es) |
| EE (1) | EE200400004A (es) |
| ES (1) | ES2186550B2 (es) |
| HR (1) | HRP20031063A2 (es) |
| HU (1) | HUP0400370A2 (es) |
| IL (1) | IL159434A0 (es) |
| IS (1) | IS7088A (es) |
| MA (1) | MA27046A1 (es) |
| MX (1) | MXPA04000185A (es) |
| NO (1) | NO20035791L (es) |
| NZ (1) | NZ530206A (es) |
| OA (1) | OA12639A (es) |
| PE (1) | PE20030134A1 (es) |
| PL (1) | PL365476A1 (es) |
| SK (1) | SK572004A3 (es) |
| WO (1) | WO2003002560A1 (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003031443A1 (en) * | 2001-10-04 | 2003-04-17 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety |
| US20070155714A1 (en) | 2003-04-30 | 2007-07-05 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Use of oxazolidinone-quinoline hybrid antibiotics for the treatment of anthrax and other infections |
| DE10340485B4 (de) | 2003-09-03 | 2015-05-13 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden |
| US7304050B2 (en) * | 2003-09-16 | 2007-12-04 | Pfizer Inc. | Antibacterial agents |
| WO2005051933A1 (en) * | 2003-11-28 | 2005-06-09 | Ranbaxy Laboratories Limited | An improved process for the synthesis of 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, a key intermediate for oxazolidinone antimicrobials and compounds prepared thereby |
| PL1709044T5 (pl) * | 2003-12-18 | 2014-03-31 | Morphochem Aktiengesellschaft Fuer Komb Chemie | Antybiotyki hybrydowe oksazolidynon-chinolon |
| US8158797B2 (en) | 2003-12-18 | 2012-04-17 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Oxazolidinone-quinolone hybrid antibiotics |
| EP1557416A1 (en) * | 2004-01-23 | 2005-07-27 | Morphochem Aktiengesellschaft Für Kombinatorische Chemie | Oxazolidinone-quinolone hybrid antibiotics |
| US20060105941A1 (en) * | 2004-11-12 | 2006-05-18 | Allergan, Inc. | Mixed antibiotic codrugs |
| CN103497173A (zh) | 2006-03-31 | 2014-01-08 | 财团法人乙卯研究所 | 具有杂环的新化合物 |
| EP2208729A4 (en) | 2007-10-02 | 2011-04-27 | Res Found Itsuu Lab | OXAZOLIDINONE DERIVATIVE WITH 7-CHAIN HETEROCYCLE |
| DK2296651T3 (da) * | 2008-05-09 | 2012-09-24 | Actelion Pharmaceuticals Ltd | 5-hydroxymethyl-oxazolidin-2-on-derivater til behandling af bakterielle intestinale sygdomme |
| SI3003289T1 (sl) | 2013-05-28 | 2019-08-30 | Morphochem Gmbh | Dajanje antibakterijskih oksazolidinon-kinolonskih hibridnih sredstev |
| EP3003307B1 (en) | 2013-05-28 | 2020-11-11 | Morphochem GmbH | Combination therapy comprising oxazolidinone-quinolones for use in treating bacterial infections |
| CN107286111B (zh) * | 2016-03-30 | 2020-06-19 | 广东赛法洛药业有限公司 | 一种噁唑烷酮化合物的制备方法 |
| CN107286182A (zh) * | 2016-04-12 | 2017-10-24 | 李靖 | 新型噁唑烷酮‑氟喹诺酮衍生物及用途 |
| US10087171B2 (en) | 2016-12-19 | 2018-10-02 | Actelion Pharmaceuticals Ltd | Crystalline forms of cadazolid |
| GB201708606D0 (en) * | 2017-05-30 | 2017-07-12 | King's College London | Antibiotic resistance breakers |
| JP7390728B2 (ja) * | 2017-11-29 | 2023-12-04 | バグワークス・リサーチ・インコーポレイテッド | 抗菌複素環式化合物及びそれらの合成 |
| CN111087409B (zh) * | 2018-10-24 | 2021-06-08 | 江阴安博生物医药有限公司 | 一种喹诺酮类化合物及其制备方法和应用 |
| CN112940038A (zh) | 2019-12-11 | 2021-06-11 | 华创合成制药股份有限公司 | 新型噁唑烷酮类化合物及其制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE444566B (sv) * | 1977-09-20 | 1986-04-21 | Bellon Labor Sa Roger | 7-dialkylamin-6-halogen-4-oxo-1,4-dihydrokinolin-3-karboxylsyra, forfarande for framstellning derav och farmaceutiskt preparat derav |
| DE69019859T2 (de) * | 1989-03-30 | 1995-10-05 | Wakunaga Seiyaku Kk | Chinolon-Derivate und deren Salze, Verfahren zu deren Herstellung und diese enthaltende antibakterielle Wirkstoffe. |
| SK283420B6 (sk) * | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
| MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
| BR9509136A (pt) * | 1994-10-26 | 1998-07-21 | Upjohn Co | Composto e uso do mesmo |
| HUP9901642A3 (en) * | 1996-01-31 | 2000-07-28 | Ube Ind Ltd Ube Shi | Remedies or preventives for aids |
| EP0892792B1 (en) * | 1996-04-11 | 2001-11-21 | PHARMACIA & UPJOHN COMPANY | Process to prepare oxazolidinones |
| GB9614236D0 (en) * | 1996-07-06 | 1996-09-04 | Zeneca Ltd | Chemical compounds |
-
2001
- 2001-06-27 ES ES200101559A patent/ES2186550B2/es not_active Expired - Fee Related
-
2002
- 2002-06-24 US US10/469,283 patent/US20040147545A1/en not_active Abandoned
- 2002-06-24 CZ CZ2004101A patent/CZ2004101A3/cs unknown
- 2002-06-24 CN CNA028128524A patent/CN1520412A/zh active Pending
- 2002-06-24 HU HU0400370A patent/HUP0400370A2/hu unknown
- 2002-06-24 EE EEP200400004A patent/EE200400004A/xx unknown
- 2002-06-24 MX MXPA04000185A patent/MXPA04000185A/es unknown
- 2002-06-24 OA OA1200300345A patent/OA12639A/en unknown
- 2002-06-24 PL PL02365476A patent/PL365476A1/xx not_active Application Discontinuation
- 2002-06-24 SK SK57-2004A patent/SK572004A3/sk unknown
- 2002-06-24 IL IL15943402A patent/IL159434A0/xx unknown
- 2002-06-24 EP EP02738497A patent/EP1401834A1/en not_active Withdrawn
- 2002-06-24 WO PCT/IB2002/002408 patent/WO2003002560A1/en active IP Right Grant
- 2002-06-24 EA EA200400086A patent/EA200400086A1/ru unknown
- 2002-06-24 CA CA002450982A patent/CA2450982A1/en not_active Abandoned
- 2002-06-24 KR KR10-2003-7017038A patent/KR20040030712A/ko not_active Application Discontinuation
- 2002-06-24 NZ NZ530206A patent/NZ530206A/en unknown
- 2002-06-24 AP APAP/P/2003/002942A patent/AP2003002942A0/en unknown
- 2002-06-24 JP JP2003508941A patent/JP2004521147A/ja active Pending
- 2002-06-24 BR BR0210667-1A patent/BR0210667A/pt not_active Application Discontinuation
- 2002-06-26 AR ARP020102399A patent/AR035254A1/es not_active Application Discontinuation
- 2002-06-26 PE PE2002000572A patent/PE20030134A1/es not_active Application Discontinuation
-
2003
- 2003-12-10 CR CR7195A patent/CR7195A/es not_active Application Discontinuation
- 2003-12-19 HR HR20031063A patent/HRP20031063A2/xx not_active Application Discontinuation
- 2003-12-22 IS IS7088A patent/IS7088A/is unknown
- 2003-12-22 NO NO20035791A patent/NO20035791L/no not_active Application Discontinuation
- 2003-12-22 BG BG108498A patent/BG108498A/xx unknown
- 2003-12-23 MA MA27460A patent/MA27046A1/fr unknown
- 2003-12-26 CO CO03112619A patent/CO5540387A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BR0210667A (pt) | 2004-10-05 |
| CN1520412A (zh) | 2004-08-11 |
| OA12639A (en) | 2006-06-15 |
| MXPA04000185A (es) | 2004-03-18 |
| HUP0400370A2 (hu) | 2004-08-30 |
| WO2003002560A1 (en) | 2003-01-09 |
| AP2003002942A0 (en) | 2003-12-24 |
| CO5540387A2 (es) | 2005-07-29 |
| IL159434A0 (en) | 2004-06-01 |
| CR7195A (es) | 2004-03-05 |
| ES2186550B2 (es) | 2003-11-16 |
| EA200400086A1 (ru) | 2004-06-24 |
| PL365476A1 (en) | 2005-01-10 |
| HRP20031063A2 (en) | 2004-04-30 |
| ES2186550A1 (es) | 2003-05-01 |
| MA27046A1 (fr) | 2004-12-20 |
| JP2004521147A (ja) | 2004-07-15 |
| US20040147545A1 (en) | 2004-07-29 |
| CZ2004101A3 (cs) | 2004-07-14 |
| EE200400004A (et) | 2004-02-16 |
| BG108498A (en) | 2005-03-31 |
| EP1401834A1 (en) | 2004-03-31 |
| AR035254A1 (es) | 2004-05-05 |
| KR20040030712A (ko) | 2004-04-09 |
| NZ530206A (en) | 2005-07-29 |
| SK572004A3 (en) | 2004-08-03 |
| PE20030134A1 (es) | 2003-04-04 |
| CA2450982A1 (en) | 2003-01-09 |
| IS7088A (is) | 2003-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |