MA27046A1 - Nouveaux derives d'oxazolidinones en tant qu'agents antibacteriens. - Google Patents

Nouveaux derives d'oxazolidinones en tant qu'agents antibacteriens.

Info

Publication number
MA27046A1
MA27046A1 MA27460A MA27460A MA27046A1 MA 27046 A1 MA27046 A1 MA 27046A1 MA 27460 A MA27460 A MA 27460A MA 27460 A MA27460 A MA 27460A MA 27046 A1 MA27046 A1 MA 27046A1
Authority
MA
Morocco
Prior art keywords
oxazolidinon
derivatives
new
antibacterial agents
antibacterial
Prior art date
Application number
MA27460A
Other languages
English (en)
Inventor
Mancini Marisabel Mourelle
Clotet Juan Huguet
Rodriguez Jose Hidalgo
Castillo Juan Carlos Del
Original Assignee
Vita Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vita Lab filed Critical Vita Lab
Publication of MA27046A1 publication Critical patent/MA27046A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MA27460A 2001-06-27 2003-12-23 Nouveaux derives d'oxazolidinones en tant qu'agents antibacteriens. MA27046A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200101559A ES2186550B2 (es) 2001-06-27 2001-06-27 Nuevos derivados de oxazolidinonas como antibacterianos.

Publications (1)

Publication Number Publication Date
MA27046A1 true MA27046A1 (fr) 2004-12-20

Family

ID=8498288

Family Applications (1)

Application Number Title Priority Date Filing Date
MA27460A MA27046A1 (fr) 2001-06-27 2003-12-23 Nouveaux derives d'oxazolidinones en tant qu'agents antibacteriens.

Country Status (29)

Country Link
US (1) US20040147545A1 (fr)
EP (1) EP1401834A1 (fr)
JP (1) JP2004521147A (fr)
KR (1) KR20040030712A (fr)
CN (1) CN1520412A (fr)
AP (1) AP2003002942A0 (fr)
AR (1) AR035254A1 (fr)
BG (1) BG108498A (fr)
BR (1) BR0210667A (fr)
CA (1) CA2450982A1 (fr)
CO (1) CO5540387A2 (fr)
CR (1) CR7195A (fr)
CZ (1) CZ2004101A3 (fr)
EA (1) EA200400086A1 (fr)
EE (1) EE200400004A (fr)
ES (1) ES2186550B2 (fr)
HR (1) HRP20031063A2 (fr)
HU (1) HUP0400370A2 (fr)
IL (1) IL159434A0 (fr)
IS (1) IS7088A (fr)
MA (1) MA27046A1 (fr)
MX (1) MXPA04000185A (fr)
NO (1) NO20035791L (fr)
NZ (1) NZ530206A (fr)
OA (1) OA12639A (fr)
PE (1) PE20030134A1 (fr)
PL (1) PL365476A1 (fr)
SK (1) SK572004A3 (fr)
WO (1) WO2003002560A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003031443A1 (fr) 2001-10-04 2003-04-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Antibiotiques a action duale renfermant une oxazolidinone et une quinolone ou une fraction de naphthyridinone
ES2308171T3 (es) * 2003-04-30 2008-12-01 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Uso de antibioticos hibridos de oxazolidinona-quinolina para el tratamiento del antrax y de otras infecciones.
DE10340485B4 (de) 2003-09-03 2015-05-13 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
WO2005051933A1 (fr) * 2003-11-28 2005-06-09 Ranbaxy Laboratories Limited Procede ameliore de synthese d'ester test-butylique d'acide 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylique, compose intermediaire cle de la preparation d'agents antimicrobiens a l'oxazolidinone, et composes ainsi prepares
US8158797B2 (en) 2003-12-18 2012-04-17 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
EP1557416A1 (fr) * 2004-01-23 2005-07-27 Morphochem Aktiengesellschaft Für Kombinatorische Chemie Oxazolidinone-quinolone antibiotiques hybrides
RU2371443C2 (ru) 2003-12-18 2009-10-27 Морфохем Акциенгезельшафт Фюр Комбинаторише Хеми Оксазолидинон-хинолонгибридные антибиотики
US20060105941A1 (en) * 2004-11-12 2006-05-18 Allergan, Inc. Mixed antibiotic codrugs
WO2007114326A1 (fr) 2006-03-31 2007-10-11 Research Foundation Itsuu Laboratory Nouveau composé ayant un hétérocycle
CN101883768A (zh) 2007-10-02 2010-11-10 财团法人乙卯研究所 具有7元杂环的噁唑烷酮衍生物
DK2296651T3 (da) * 2008-05-09 2012-09-24 Actelion Pharmaceuticals Ltd 5-hydroxymethyl-oxazolidin-2-on-derivater til behandling af bakterielle intestinale sygdomme
AU2014273510B2 (en) 2013-05-28 2019-10-10 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibacterials for the parenteral treatment or prophylaxis of bacterial diseases
AU2014273471B2 (en) 2013-05-28 2019-10-03 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Combination therapy comprising oxazolidinone-quinolones for use in treating bacterial infections
CN107286111B (zh) * 2016-03-30 2020-06-19 广东赛法洛药业有限公司 一种噁唑烷酮化合物的制备方法
CN107286182A (zh) * 2016-04-12 2017-10-24 李靖 新型噁唑烷酮‑氟喹诺酮衍生物及用途
US10087171B2 (en) 2016-12-19 2018-10-02 Actelion Pharmaceuticals Ltd Crystalline forms of cadazolid
GB201708606D0 (en) 2017-05-30 2017-07-12 King's College London Antibiotic resistance breakers
ES2952989T3 (es) * 2017-11-29 2023-11-07 Bugworks Res Inc Compuestos heterocíclicos antibacterianos y su síntesis
CN111087409B (zh) * 2018-10-24 2021-06-08 江阴安博生物医药有限公司 一种喹诺酮类化合物及其制备方法和应用
CN112940038A (zh) * 2019-12-11 2021-06-11 华创合成制药股份有限公司 新型噁唑烷酮类化合物及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE444566B (sv) * 1977-09-20 1986-04-21 Bellon Labor Sa Roger 7-dialkylamin-6-halogen-4-oxo-1,4-dihydrokinolin-3-karboxylsyra, forfarande for framstellning derav och farmaceutiskt preparat derav
EP0390215B1 (fr) * 1989-03-30 1995-06-07 Wakunaga Seiyaku Kabushiki Kaisha Dérivés de quinolone et leurs sels, procédés pour leur préparation et agents antibactériens les contenant
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
RU2134692C1 (ru) * 1994-10-26 1999-08-20 Фармация Энд Апджон Компани Антимикробные фенилоксазолидиноны
CN1214632A (zh) * 1996-01-31 1999-04-21 三共株式会社 艾滋病治疗剂或预防剂
RU2176643C2 (ru) * 1996-04-11 2001-12-10 Фармация Энд Апджон Компани Способ получения 5-гидроксиметил замещенных оксазолидинонов, способ получения 5-аминометил замещенных оксазолидиноновых аминов, оксазолидинонсульфонат
GB9614236D0 (en) * 1996-07-06 1996-09-04 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
AR035254A1 (es) 2004-05-05
ES2186550A1 (es) 2003-05-01
PL365476A1 (en) 2005-01-10
CZ2004101A3 (cs) 2004-07-14
EA200400086A1 (ru) 2004-06-24
BR0210667A (pt) 2004-10-05
EP1401834A1 (fr) 2004-03-31
JP2004521147A (ja) 2004-07-15
NO20035791L (no) 2004-02-19
PE20030134A1 (es) 2003-04-04
EE200400004A (et) 2004-02-16
CO5540387A2 (es) 2005-07-29
NZ530206A (en) 2005-07-29
IS7088A (is) 2003-12-22
KR20040030712A (ko) 2004-04-09
HUP0400370A2 (hu) 2004-08-30
CN1520412A (zh) 2004-08-11
CR7195A (es) 2004-03-05
ES2186550B2 (es) 2003-11-16
WO2003002560A1 (fr) 2003-01-09
IL159434A0 (en) 2004-06-01
AP2003002942A0 (en) 2003-12-24
CA2450982A1 (fr) 2003-01-09
US20040147545A1 (en) 2004-07-29
BG108498A (en) 2005-03-31
SK572004A3 (en) 2004-08-03
MXPA04000185A (es) 2004-03-18
HRP20031063A2 (en) 2004-04-30
OA12639A (en) 2006-06-15

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