NO20034438L - Fremgangsmåte for fremstilling av et 7-kinolyl-3,5- dihydroksyhept-6-enoeat - Google Patents
Fremgangsmåte for fremstilling av et 7-kinolyl-3,5- dihydroksyhept-6-enoeatInfo
- Publication number
- NO20034438L NO20034438L NO20034438A NO20034438A NO20034438L NO 20034438 L NO20034438 L NO 20034438L NO 20034438 A NO20034438 A NO 20034438A NO 20034438 A NO20034438 A NO 20034438A NO 20034438 L NO20034438 L NO 20034438L
- Authority
- NO
- Norway
- Prior art keywords
- formula
- dihydroxyhept
- chem
- compound represented
- enoate
- Prior art date
Links
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- NEHKARMWCGDCNP-UHFFFAOYSA-N 3,5-dihydroxy-7-quinolin-2-ylhept-6-enoic acid Chemical compound C1=CC=CC2=NC(C=CC(O)CC(O)CC(O)=O)=CC=C21 NEHKARMWCGDCNP-UHFFFAOYSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001639 boron compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 229910000033 sodium borohydride Inorganic materials 0.000 abstract 1
- 239000012279 sodium borohydride Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001106820 | 2001-04-05 | ||
PCT/JP2002/002779 WO2002081451A1 (fr) | 2001-04-05 | 2002-03-22 | Procede relatif a l'elaboration de 7-quinolinyl-3,5-dihydroxyhept-6-enoate |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20034438L true NO20034438L (no) | 2003-10-03 |
NO20034438D0 NO20034438D0 (no) | 2003-10-03 |
NO326089B1 NO326089B1 (no) | 2008-09-15 |
Family
ID=18959261
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20034438A NO326089B1 (no) | 2001-04-05 | 2003-10-03 | Fremgangsmate for fremstilling av et 7-kinolyl-3,5-dihydroksyhept-6-enoeat |
Country Status (21)
Country | Link |
---|---|
US (1) | US7038056B2 (no) |
EP (1) | EP1375485B1 (no) |
JP (1) | JP4380160B2 (no) |
KR (1) | KR100838135B1 (no) |
CN (1) | CN1241914C (no) |
AT (1) | ATE506349T1 (no) |
AU (1) | AU2002241271B2 (no) |
CA (1) | CA2442713C (no) |
CZ (1) | CZ20032633A3 (no) |
DE (1) | DE60239793D1 (no) |
HU (1) | HUP0401401A3 (no) |
IL (2) | IL158151A0 (no) |
MX (1) | MXPA03009095A (no) |
NO (1) | NO326089B1 (no) |
NZ (1) | NZ528149A (no) |
RU (1) | RU2260001C2 (no) |
SK (1) | SK287922B6 (no) |
TW (1) | TWI317356B (no) |
UA (1) | UA76984C2 (no) |
WO (1) | WO2002081451A1 (no) |
ZA (1) | ZA200307704B (no) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100445267C (zh) * | 2005-10-21 | 2008-12-24 | 上海医药工业研究院 | 4-(4-氟-苯基)-3-羟甲基-2-环丙基-喹啉的制备方法 |
KR101160152B1 (ko) * | 2009-02-24 | 2012-06-27 | 한미사이언스 주식회사 | 스타틴 화합물 또는 그 염의 신규 제조방법, 및 이에 사용되는 중간체 화합물 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4248882A (en) * | 1980-02-12 | 1981-02-03 | Pfizer Inc. | Treating diabetes-associated complications with hydantoin amines |
US4645854A (en) * | 1985-04-25 | 1987-02-24 | Merck & Co., Inc. | Process for preparing HMG-CoA reductase inhibitors with a 3,5-dihydroxypentanoate subunit |
CA1282425C (en) | 1984-06-04 | 1991-04-02 | Meyer Sletzinger | Process for preparing hmg-coa reductase inhibitors with a 3,5-dihydroxypentanoate subunit |
CA1336714C (en) | 1987-08-20 | 1995-08-15 | Yoshihiro Fujikawa | Quinoline type mevalonolactone inhibitors of cholesterol biosynthesis |
JP2569746B2 (ja) * | 1987-08-20 | 1997-01-08 | 日産化学工業株式会社 | キノリン系メバロノラクトン類 |
US5753675A (en) * | 1989-03-03 | 1998-05-19 | Novartis Pharmaceuticals Corporation | Quinoline analogs of mevalonolactone and derivatives thereof |
JP3528186B2 (ja) * | 1991-06-24 | 2004-05-17 | 日産化学工業株式会社 | 光学活性キノリンメバロン酸のジアステレオマー塩 |
JP3554036B2 (ja) * | 1994-09-06 | 2004-08-11 | 宇部興産株式会社 | 光学活性な7−置換キノリル−3,5−ジヒドロキシ−ヘプト−6−エン酸エステル誘導体の製造方法 |
JP2001526256A (ja) * | 1997-12-19 | 2001-12-18 | ワーナー−ランバート・エクスポート・リミテッド | 1,3−ジオールの合成方法 |
JP4236463B2 (ja) * | 2000-10-13 | 2009-03-11 | ダイセル化学工業株式会社 | 光学活性な(3r,5s,6e)−7−[2−シクロプロピル−4−(4−フルオロフェニル)キノリン−3−イル]−3,5−ジヒドロキシ−6−ヘプテン酸エチルの製造方法 |
EP1365029A4 (en) * | 2001-02-02 | 2009-07-29 | Mitsubishi Chem Corp | PROCESS FOR PRODUCING ACID ESTERS (3R, 5S) - (E) -7- 2-CYCLOPROPYL-4- (4-FLUOROPHENYL) -QUINOLIN-3-YL-3,5-DIHYDROXYHEPT-6-ENIC |
-
2002
- 2002-03-22 RU RU2003132440/04A patent/RU2260001C2/ru not_active IP Right Cessation
- 2002-03-22 US US10/473,132 patent/US7038056B2/en not_active Expired - Fee Related
- 2002-03-22 KR KR1020037012898A patent/KR100838135B1/ko not_active IP Right Cessation
- 2002-03-22 CA CA2442713A patent/CA2442713C/en not_active Expired - Fee Related
- 2002-03-22 CZ CZ20032633A patent/CZ20032633A3/cs unknown
- 2002-03-22 UA UA2003098877A patent/UA76984C2/uk unknown
- 2002-03-22 WO PCT/JP2002/002779 patent/WO2002081451A1/ja active IP Right Grant
- 2002-03-22 CN CNB028078454A patent/CN1241914C/zh not_active Expired - Fee Related
- 2002-03-22 IL IL15815102A patent/IL158151A0/xx unknown
- 2002-03-22 NZ NZ528149A patent/NZ528149A/en not_active IP Right Cessation
- 2002-03-22 JP JP2002579439A patent/JP4380160B2/ja not_active Expired - Lifetime
- 2002-03-22 DE DE60239793T patent/DE60239793D1/de not_active Expired - Lifetime
- 2002-03-22 AU AU2002241271A patent/AU2002241271B2/en not_active Ceased
- 2002-03-22 EP EP02707129A patent/EP1375485B1/en not_active Expired - Lifetime
- 2002-03-22 MX MXPA03009095A patent/MXPA03009095A/es active IP Right Grant
- 2002-03-22 HU HU0401401A patent/HUP0401401A3/hu unknown
- 2002-03-22 AT AT02707129T patent/ATE506349T1/de not_active IP Right Cessation
- 2002-03-22 SK SK1237-2003A patent/SK287922B6/sk not_active IP Right Cessation
- 2002-04-02 TW TW091106610A patent/TWI317356B/zh active
-
2003
- 2003-09-29 IL IL158151A patent/IL158151A/en not_active IP Right Cessation
- 2003-10-02 ZA ZA200307704A patent/ZA200307704B/xx unknown
- 2003-10-03 NO NO20034438A patent/NO326089B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL158151A (en) | 2009-09-22 |
SK12372003A3 (sk) | 2004-04-06 |
UA76984C2 (en) | 2006-10-16 |
TWI317356B (no) | 2009-11-21 |
ZA200307704B (en) | 2004-10-04 |
EP1375485A1 (en) | 2004-01-02 |
JP4380160B2 (ja) | 2009-12-09 |
RU2003132440A (ru) | 2005-01-10 |
KR20030086342A (ko) | 2003-11-07 |
CN1241914C (zh) | 2006-02-15 |
CZ20032633A3 (cs) | 2003-12-17 |
KR100838135B1 (ko) | 2008-06-13 |
WO2002081451A1 (fr) | 2002-10-17 |
CA2442713C (en) | 2010-05-18 |
MXPA03009095A (es) | 2004-02-12 |
NO326089B1 (no) | 2008-09-15 |
US7038056B2 (en) | 2006-05-02 |
US20050014947A1 (en) | 2005-01-20 |
NZ528149A (en) | 2005-05-27 |
HUP0401401A3 (en) | 2012-05-02 |
EP1375485A4 (en) | 2005-03-23 |
IL158151A0 (en) | 2004-03-28 |
DE60239793D1 (de) | 2011-06-01 |
ATE506349T1 (de) | 2011-05-15 |
SK287922B6 (sk) | 2012-04-03 |
EP1375485B1 (en) | 2011-04-20 |
CN1500079A (zh) | 2004-05-26 |
RU2260001C2 (ru) | 2005-09-10 |
NO20034438D0 (no) | 2003-10-03 |
JPWO2002081451A1 (ja) | 2004-07-29 |
AU2002241271B2 (en) | 2007-01-25 |
CA2442713A1 (en) | 2002-10-17 |
HUP0401401A2 (hu) | 2004-12-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |