NO20032806L - Sukkersubstituerte 2-azetidinoner anvendelige som hypokolesterolemiske midler - Google Patents

Sukkersubstituerte 2-azetidinoner anvendelige som hypokolesterolemiske midler

Info

Publication number
NO20032806L
NO20032806L NO20032806A NO20032806A NO20032806L NO 20032806 L NO20032806 L NO 20032806L NO 20032806 A NO20032806 A NO 20032806A NO 20032806 A NO20032806 A NO 20032806A NO 20032806 L NO20032806 L NO 20032806L
Authority
NO
Norway
Prior art keywords
sugar
substituted
hypocholesterolemic agents
azetidinones useful
azetidinones
Prior art date
Application number
NO20032806A
Other languages
English (en)
Other versions
NO326981B1 (no
NO20032806D0 (no
Inventor
Anima Ghosal
Shmuel Zbaida
Swapan K Chowdhury
Robert M Iannucci
Wenqing Feng
Kevin B Alton
James E Patrick
Harry R Davis
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22973953&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20032806(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO20032806D0 publication Critical patent/NO20032806D0/no
Publication of NO20032806L publication Critical patent/NO20032806L/no
Publication of NO326981B1 publication Critical patent/NO326981B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
NO20032806A 2000-12-20 2003-06-19 Sukkersubstituerte 2-azetidinoner anvendelige som hypokolesterolemiske midler, farmasoytisk preparat og anvendelse av forbindelsene for fremstilling av et medikament NO326981B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25687500P 2000-12-20 2000-12-20
PCT/US2001/049127 WO2002050090A1 (en) 2000-12-20 2001-12-17 Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents

Publications (3)

Publication Number Publication Date
NO20032806D0 NO20032806D0 (no) 2003-06-19
NO20032806L true NO20032806L (no) 2003-08-19
NO326981B1 NO326981B1 (no) 2009-03-30

Family

ID=22973953

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20032806A NO326981B1 (no) 2000-12-20 2003-06-19 Sukkersubstituerte 2-azetidinoner anvendelige som hypokolesterolemiske midler, farmasoytisk preparat og anvendelse av forbindelsene for fremstilling av et medikament
NO20083737A NO20083737L (no) 2000-12-20 2008-08-29 Hydroksysubstituerte 2-azetidinoner som er anvendbare som hypokolesterolemiske midler

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20083737A NO20083737L (no) 2000-12-20 2008-08-29 Hydroksysubstituerte 2-azetidinoner som er anvendbare som hypokolesterolemiske midler

Country Status (35)

Country Link
US (1) US20020137690A1 (no)
EP (1) EP1347987B1 (no)
JP (2) JP4351842B2 (no)
KR (1) KR100883461B1 (no)
CN (1) CN100475829C (no)
AR (1) AR035611A1 (no)
AT (2) ATE369334T1 (no)
AU (2) AU2002231049B2 (no)
BR (1) BR0116212A (no)
CA (1) CA2432798C (no)
CY (1) CY1106912T1 (no)
CZ (1) CZ302193B6 (no)
DE (2) DE60129863T2 (no)
DK (2) DK1347987T3 (no)
EC (1) ECSP034659A (no)
ES (2) ES2287826T3 (no)
GE (1) GEP20053548B (no)
HK (2) HK1056735A1 (no)
HU (1) HUP0302269A3 (no)
IL (1) IL155771A0 (no)
MA (1) MA26975A1 (no)
MX (1) MXPA03005671A (no)
MY (1) MY129148A (no)
NO (2) NO326981B1 (no)
NZ (1) NZ525722A (no)
PE (1) PE20020718A1 (no)
PL (1) PL208242B1 (no)
PT (2) PT1593670E (no)
RU (1) RU2297422C2 (no)
SI (2) SI1593670T1 (no)
SK (1) SK286703B6 (no)
TR (1) TR200402758T4 (no)
TW (1) TWI316942B (no)
WO (1) WO2002050090A1 (no)
ZA (1) ZA200303694B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL157552A0 (en) 2001-03-28 2004-03-28 Schering Corp Enantioselective synthesis of azetidinone intermediate compounds
GB0215579D0 (en) * 2002-07-05 2002-08-14 Astrazeneca Ab Chemical compounds
AR040588A1 (es) 2002-07-26 2005-04-13 Schering Corp Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
JP2005015434A (ja) 2003-06-27 2005-01-20 Kotobuki Seiyaku Kk 血清コレステロール低下剤或はアテローム性硬化症の予防又は治療剤
EP1522541A1 (en) * 2003-10-07 2005-04-13 Lipideon Biotechnology AG Novel hypocholesterolemic compounds
EP1918000A2 (en) 2003-11-05 2008-05-07 Schering Corporation Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
GB0329778D0 (en) * 2003-12-23 2004-01-28 Astrazeneca Ab Chemical compounds
US7871998B2 (en) 2003-12-23 2011-01-18 Astrazeneca Ab Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity
AU2004308332B2 (en) 2003-12-23 2008-04-10 Merck Sharp & Dohme Corp. Anti-hypercholesterolemic compounds
EP1807070A1 (en) * 2004-09-29 2007-07-18 Schering Corporation Combinations of substituted azetidinones and cb1 antagonists
US7737155B2 (en) 2005-05-17 2010-06-15 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
AR054482A1 (es) * 2005-06-22 2007-06-27 Astrazeneca Ab Derivados de azetidinona para el tratamiento de hiperlipidemias
SA06270191B1 (ar) * 2005-06-22 2010-03-29 استرازينيكا ايه بي مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
CA2644905A1 (en) * 2006-03-06 2007-09-13 Teva Pharmaceutical Industries Ltd. Ezetimibe compositions
AR060623A1 (es) 2006-04-27 2008-07-02 Astrazeneca Ab Compuestos derivados de 2-azetidinona y un metodo de preparacion
AR065913A1 (es) * 2007-04-02 2009-07-08 Theracos Inc Derivados de glicosido bencilico, composicion y combinacion farmaceutica y uso
US20110243940A1 (en) 2008-12-16 2011-10-06 Schering Corporation Bicyclic pyranone derivatives and methods of use thereof
EP2379547A1 (en) 2008-12-16 2011-10-26 Schering Corporation Pyridopyrimidine derivatives and methods of use thereof
KR20110120320A (ko) * 2009-02-11 2011-11-03 다우 아그로사이언시즈 엘엘씨 살충 조성물
EP2403848A1 (en) 2009-03-06 2012-01-11 Lipideon Biotechnology AG Pharmaceutical hypocholesterolemic compositions
CA2757722C (en) 2009-04-01 2018-05-22 Matrix Laboratories Ltd. Enzymatic process for the preparation of (s)-5-(4-fluoro-phenyl)-5-hydroxy- 1morpholin-4-yl-pentan-1-one, an intermediate of ezetimibe and further conversion to ezetimibe
CN101993403B (zh) 2009-08-11 2012-07-11 浙江海正药业股份有限公司 氮杂环丁酮类化合物及医药应用
KR101102749B1 (ko) * 2009-11-30 2012-01-05 최길용 곱셈 학습기
KR20150079373A (ko) 2013-12-30 2015-07-08 한미약품 주식회사 에제티미브 및 로수바스타틴을 포함하는 경구용 복합제제
CN105055404B (zh) * 2015-08-19 2017-07-18 四川大学 Hmgcs2抑制剂在制备治疗可卡因成瘾的药物中的用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3595B (en) * 1993-01-21 1995-12-27 Schering Corp Spirocycloalkyl-substituted azetidinones useful as hypocholesterolemic agents
US5631365A (en) * 1993-09-21 1997-05-20 Schering Corporation Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
US5627176A (en) * 1994-03-25 1997-05-06 Schering Corporation Substituted azetidinone compounds useful as hypocholesterolemic agents
US5633246A (en) * 1994-11-18 1997-05-27 Schering Corporation Sulfur-substituted azetidinone compounds useful as hypocholesterolemic agents
DK0877750T3 (da) * 1995-10-31 2002-07-15 Schering Corp Som hypocholesterolemiske midler velegnede, sukkersubstituerede 2-azetidinoner
US5756470A (en) * 1996-10-29 1998-05-26 Schering Corporation Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
AUPQ342599A0 (en) * 1999-10-14 1999-11-04 University Of Melbourne, The Conjugates and uses thereof

Also Published As

Publication number Publication date
EP1347987B1 (en) 2004-10-13
CA2432798C (en) 2007-02-27
ATE279425T1 (de) 2004-10-15
HK1056735A1 (en) 2004-02-27
MY129148A (en) 2007-03-30
DK1593670T3 (da) 2007-11-05
SI1593670T1 (sl) 2007-12-31
NZ525722A (en) 2004-11-26
CN100475829C (zh) 2009-04-08
EP1347987A1 (en) 2003-10-01
RU2003122520A (ru) 2005-02-27
HUP0302269A3 (en) 2009-08-28
CY1106912T1 (el) 2012-09-26
WO2002050090A1 (en) 2002-06-27
US20020137690A1 (en) 2002-09-26
ZA200303694B (en) 2004-08-13
GEP20053548B (en) 2005-06-27
CA2432798A1 (en) 2002-06-27
DE60129863T2 (de) 2008-04-30
TWI316942B (en) 2009-11-11
MA26975A1 (fr) 2004-12-20
KR20030063414A (ko) 2003-07-28
SK286703B6 (sk) 2009-03-05
NO20083737L (no) 2003-08-19
JP2009132745A (ja) 2009-06-18
MXPA03005671A (es) 2003-10-06
ATE369334T1 (de) 2007-08-15
PT1347987E (pt) 2005-01-31
WO2002050090A8 (en) 2004-04-15
NO326981B1 (no) 2009-03-30
SK7702003A3 (en) 2003-10-07
AU2002231049B2 (en) 2006-07-20
KR100883461B1 (ko) 2009-02-16
SI1347987T1 (en) 2005-02-28
JP2004516299A (ja) 2004-06-03
AU3104902A (en) 2002-07-01
DE60106489T2 (de) 2005-10-13
ES2230385T3 (es) 2005-05-01
DE60106489D1 (de) 2004-11-18
DK1347987T3 (da) 2005-01-31
PL208242B1 (pl) 2011-04-29
ECSP034659A (es) 2003-07-25
AR035611A1 (es) 2004-06-16
NO20032806D0 (no) 2003-06-19
IL155771A0 (en) 2003-12-23
DE60129863D1 (de) 2007-09-20
CZ302193B6 (cs) 2010-12-08
RU2297422C2 (ru) 2007-04-20
HK1084945A1 (en) 2006-08-11
TR200402758T4 (tr) 2004-11-22
ES2287826T3 (es) 2007-12-16
CN1483039A (zh) 2004-03-17
HUP0302269A2 (hu) 2003-10-28
PE20020718A1 (es) 2002-08-09
PT1593670E (pt) 2007-11-08
BR0116212A (pt) 2003-12-30
JP4351842B2 (ja) 2009-10-28
CZ20031674A3 (cs) 2003-10-15
PL363237A1 (en) 2004-11-15

Similar Documents

Publication Publication Date Title
NO20032806L (no) Sukkersubstituerte 2-azetidinoner anvendelige som hypokolesterolemiske midler
DE50102748D1 (de) Antriebseinheit
AU2002231049A1 (en) Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
DE60109777D1 (de) Plattenlaufwerk
AR027983A1 (es) Novedosos compuestos
NO20032272L (no) Bifenylkarboksamider nyttige som lipidsenkende midler
FR2819837B3 (fr) Panneau acoustique
DE60004978D1 (de) Kombinationswerkzeug
PT1299356E (pt) Novos compostos
AR028220A1 (es) Novedosos compuestos
ATA16142000A (de) Plattenaufteilsäge
NO20026035L (no) Drivenhet
DE50203277D1 (de) Getriebe-antriebseinheit
DE50107617D1 (de) Bedieneinheit
AT503224A3 (de) Holzbautafel
FI20001146A (fi) Z-kampimekanismi
DE50200237D1 (de) Übertragungseinheit
AR028399A1 (es) Nuevos compuestos
DE50108345D1 (de) Getriebe-antriebseinheit
ES1047687Y (es) Panel mejorado para la construccion.
ITBO20000530A0 (it) Macchina sezionatrice di pannelli
DE60102324D1 (de) Mischeinheit
ITBO20000531A0 (it) Macchina sezionatrice di pannelli
IT1319252B1 (it) Pannello ignifugo.
ATA20312000A (de) Stromrichtergespeiste antriebseinheit

Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: MERCK SHARP AND DOHME CORP

Free format text: NEW ADDRESS: 126 EAST LINCOLN AVENUE, US-NJ07065 RAHWAY, US

MM1K Lapsed by not paying the annual fees