NO20031952L - 3-aroylinderivater og deres anvendelse som CB2 reseptoragonister - Google Patents

3-aroylinderivater og deres anvendelse som CB2 reseptoragonister

Info

Publication number
NO20031952L
NO20031952L NO20031952A NO20031952A NO20031952L NO 20031952 L NO20031952 L NO 20031952L NO 20031952 A NO20031952 A NO 20031952A NO 20031952 A NO20031952 A NO 20031952A NO 20031952 L NO20031952 L NO 20031952L
Authority
NO
Norway
Prior art keywords
aroylin
derivatives
receptor agonists
agonists
receptor
Prior art date
Application number
NO20031952A
Other languages
English (en)
Norwegian (no)
Other versions
NO20031952D0 (no
Inventor
Francis Barth
Christian Congy
Carole Guillaumont
Murielle Rinaldi
Fabienne Vasse
Claude Vernhet
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of NO20031952D0 publication Critical patent/NO20031952D0/no
Publication of NO20031952L publication Critical patent/NO20031952L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
NO20031952A 2000-11-22 2003-04-29 3-aroylinderivater og deres anvendelse som CB2 reseptoragonister NO20031952L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0015158A FR2816938B1 (fr) 2000-11-22 2000-11-22 Derives de 3-aroylindole, leur procede de preparation et les compositions pharmaceutiques en contenant
PCT/FR2001/003665 WO2002042269A1 (fr) 2000-11-22 2001-11-21 Derives de 3-aroylindole et leur utilisation en tant qu'agonistes des recepteurs cb2

Publications (2)

Publication Number Publication Date
NO20031952D0 NO20031952D0 (no) 2003-04-29
NO20031952L true NO20031952L (no) 2003-07-22

Family

ID=8856819

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20031952A NO20031952L (no) 2000-11-22 2003-04-29 3-aroylinderivater og deres anvendelse som CB2 reseptoragonister

Country Status (32)

Country Link
US (1) US6995184B2 (ko)
EP (1) EP1339679B1 (ko)
JP (1) JP4264258B2 (ko)
KR (1) KR20030048161A (ko)
CN (1) CN1234688C (ko)
AR (1) AR033594A1 (ko)
AT (1) ATE301638T1 (ko)
AU (1) AU2002222001A1 (ko)
BG (1) BG107827A (ko)
BR (1) BR0115580A (ko)
CA (1) CA2427444A1 (ko)
CZ (1) CZ20031392A3 (ko)
DE (1) DE60112607T2 (ko)
DK (1) DK1339679T3 (ko)
DZ (1) DZ3443A1 (ko)
EA (1) EA005854B1 (ko)
EE (1) EE200300244A (ko)
ES (1) ES2247201T3 (ko)
FR (1) FR2816938B1 (ko)
HR (1) HRP20030417A2 (ko)
HU (1) HUP0400561A2 (ko)
IL (1) IL155634A0 (ko)
IS (1) IS6802A (ko)
MA (1) MA26959A1 (ko)
MX (1) MXPA03004549A (ko)
NO (1) NO20031952L (ko)
NZ (1) NZ525609A (ko)
PL (1) PL362276A1 (ko)
SK (1) SK6042003A3 (ko)
TW (1) TWI224592B (ko)
WO (1) WO2002042269A1 (ko)
ZA (1) ZA200303728B (ko)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200407110A (en) * 2001-11-23 2004-05-16 Astrazeneca Ab New use for the treatment of gastroesophageal reflux disease
JP2006517194A (ja) 2002-06-06 2006-07-20 イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム 骨成長を調節するための方法、組成物および製造物
ATE375349T1 (de) 2002-08-02 2007-10-15 Merck & Co Inc Substituierte furo(2,3-b)pyridin derivate
FR2843964B1 (fr) * 2002-08-29 2004-10-01 Sanofi Synthelabo Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique
FR2847899B1 (fr) * 2002-11-29 2006-04-28 Sanofi Synthelabo Derives d'indole-3-carboxamide, leur preparation et leur application en therapeutique
FR2854633B1 (fr) * 2003-05-07 2005-06-24 Sanofi Synthelabo Derives de piperidinyl-et piperazinyl-alkylcarbamates, leur preparation et leur application en therapeutique
FR2856684B1 (fr) 2003-06-26 2008-04-11 Sanofi Synthelabo Derives de diphenylpyridine, leur preparation et leur application en therapeutique
FR2865205B1 (fr) 2004-01-16 2006-02-24 Sanofi Synthelabo Derives de type aryloxyalkylcarbamates, leur preparation et leur application en therapeutique
CA2571679A1 (en) * 2004-06-22 2005-12-29 Pharmos Limited Use of cb2 receptors agonists for the treatment of huntington's disease
KR20070041717A (ko) 2004-07-12 2007-04-19 카딜라 핼쓰캐어 리미티드 카나비노이드 수용체 조절자인 트리시클릭 피라졸 유도체들
US20060025448A1 (en) 2004-07-22 2006-02-02 Cadila Healthcare Limited Hair growth stimulators
CA2587210A1 (en) * 2004-11-22 2006-06-01 Threshold Pharmaceuticals, Inc. Tubulin binding anti cancer agents and prodrugs thereof
EP1833824B1 (en) * 2004-12-21 2016-08-03 AbbVie Inc. 3-cycloalkylcarbonyl indoles as cannabinoid receptor ligands
FR2893615B1 (fr) 2005-11-18 2008-03-07 Sanofi Aventis Sa Derives de 3-acylindole, leur preparation et leur application en therapeutique
CA2647598A1 (en) * 2006-05-31 2007-12-06 Abbott Laboratories Compounds as cannabinoid receptor ligands and uses thereof
US8841334B2 (en) * 2006-05-31 2014-09-23 Abbvie Inc. Compounds as cannabinoid receptor ligands and uses thereof
GB0702862D0 (en) * 2007-02-14 2007-03-28 Univ Aberdeen Therapeutic compounds
CA2681586A1 (en) 2007-03-28 2008-10-09 Abbott Laboratories 1, 3-thiazol-2 (3h) -ylidene compounds as cannabinoid receptor ligands
US7872033B2 (en) 2007-04-17 2011-01-18 Abbott Laboratories Compounds as cannabinoid receptor ligands
FR2915199B1 (fr) * 2007-04-18 2010-01-22 Sanofi Aventis Derives de triazolopyridine-carboxamides et triazolopyrimidine-carboxamides, leur preparation et leur application en therapeutique.
CN101711253A (zh) * 2007-05-18 2010-05-19 雅培制药有限公司 用作大麻素受体配体的新化合物
US9193713B2 (en) * 2007-10-12 2015-11-24 Abbvie Inc. Compounds as cannabinoid receptor ligands
FR2933697B1 (fr) * 2008-07-11 2010-08-13 Sanofi Aventis Derives de 1-benzyl-cinnolin-4-(1h)-one substitues, leur preparation et leur application en therapeutique
US8846730B2 (en) * 2008-09-08 2014-09-30 Abbvie Inc. Compounds as cannabinoid receptor ligands
EP2428507B1 (en) * 2008-09-16 2015-10-21 AbbVie Bahamas Ltd. Cannabinoid receptor ligands
PA8854001A1 (es) * 2008-12-16 2010-07-27 Abbott Lab Compuestos novedosos como ligandos de receptores de canabinoides
FR2941696B1 (fr) 2009-02-05 2011-04-15 Sanofi Aventis Derives d'azaspiranyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
FR2945533B1 (fr) 2009-05-12 2011-05-27 Sanofi Aventis Derives de cyclopenta°c!pyrrolyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
WO2011009883A1 (en) 2009-07-23 2011-01-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Selective cb2 receptor agonists for use in the prevention or treatment of alcoholic liver disease
FR2950055A1 (fr) 2009-09-17 2011-03-18 Sanofi Aventis Derives de 3-amino-cinnolin-4(1h)-one substitues, leur preparation et leur application en therapeutique
WO2011100359A1 (en) * 2010-02-09 2011-08-18 Ironwood Pharmaceuticals, Inc. Cannabinoid agonists
FR2983859B1 (fr) 2011-12-12 2014-01-17 Sanofi Sa Derives de 1,3,5-triazine-2-amine, leur preparation et leur application en diagnostique et en therapeutique
AP2016009270A0 (en) * 2013-11-28 2016-06-30 Commw Scient Ind Res Org Method of detecting plasmodium infection
CN108794379A (zh) * 2017-04-26 2018-11-13 华东师范大学 1h-吲哚-2-甲酰胺衍生物及其制备方法和应用
WO2022128050A1 (en) 2020-12-14 2022-06-23 Symrise Ag Medicament for fighting inflammation and pain

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532237A (en) * 1995-02-15 1996-07-02 Merck Frosst Canada, Inc. Indole derivatives with affinity for the cannabinoid receptor
FR2735774B1 (fr) * 1995-06-21 1997-09-12 Sanofi Sa Utilisation de composes agonistes du recepteur cb2 humain pour la preparation de medicaments immunomodulateurs, nouveaux composes agonistes du recepteur cb2 et les compositions pharmaceutiques les contenant
AU1095101A (en) * 1999-10-18 2001-04-30 University Of Connecticut, The Cannabimimetic indole derivatives

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ATE301638T1 (de) 2005-08-15
KR20030048161A (ko) 2003-06-18
CN1483023A (zh) 2004-03-17
DZ3443A1 (fr) 2002-05-30
FR2816938B1 (fr) 2003-01-03
TWI224592B (en) 2004-12-01
EA005854B1 (ru) 2005-06-30
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HRP20030417A2 (en) 2003-08-31
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JP4264258B2 (ja) 2009-05-13
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IL155634A0 (en) 2003-11-23
FR2816938A1 (fr) 2002-05-24
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