NO20031722D0 - Nye 7-azaindoler, anvendelse av de samme som fosfodiesterase- 4-inhibitorerog fremgangsmåte for fremstilling av de samme - Google Patents

Nye 7-azaindoler, anvendelse av de samme som fosfodiesterase- 4-inhibitorerog fremgangsmåte for fremstilling av de samme

Info

Publication number
NO20031722D0
NO20031722D0 NO20031722A NO20031722A NO20031722D0 NO 20031722 D0 NO20031722 D0 NO 20031722D0 NO 20031722 A NO20031722 A NO 20031722A NO 20031722 A NO20031722 A NO 20031722A NO 20031722 D0 NO20031722 D0 NO 20031722D0
Authority
NO
Norway
Prior art keywords
same
azaindoles
phosphodiesterase
inhibitors
preparing
Prior art date
Application number
NO20031722A
Other languages
English (en)
Other versions
NO324947B1 (no
NO20031722L (no
Inventor
Norbert Hoefgren
Ute Egerland
Thomas Kronbach
Degenhard Marx
Stefan Szelenyi
Hildegard Kuss
Emmanuel Polymeropoulos
Original Assignee
Elbion Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10053275A external-priority patent/DE10053275A1/de
Application filed by Elbion Ag filed Critical Elbion Ag
Publication of NO20031722D0 publication Critical patent/NO20031722D0/no
Publication of NO20031722L publication Critical patent/NO20031722L/no
Publication of NO324947B1 publication Critical patent/NO324947B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P33/00—Antiparasitic agents
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • AIDS & HIV (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
NO20031722A 2000-10-27 2003-04-14 7-azaindoler,legemiddel inneholdende slike, anvendelser derav samt fremgangsmate for deres fremstilling NO324947B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10053275A DE10053275A1 (de) 2000-10-27 2000-10-27 Neue 7-Azaindole, deren Verwendung als Inhibitoren der Phosphodiesterase 4 und Verfahren zu deren Herstellung
US24434200P 2000-10-30 2000-10-30
PCT/EP2001/012376 WO2002034747A1 (de) 2000-10-27 2001-10-25 Neue 7-azaindole, deren verwendung als inhibitoren der phosphodiesterase 4 und verfahren zu deren herstellung

Publications (3)

Publication Number Publication Date
NO20031722D0 true NO20031722D0 (no) 2003-04-14
NO20031722L NO20031722L (no) 2003-04-14
NO324947B1 NO324947B1 (no) 2008-01-07

Family

ID=26007507

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20031722A NO324947B1 (no) 2000-10-27 2003-04-14 7-azaindoler,legemiddel inneholdende slike, anvendelser derav samt fremgangsmate for deres fremstilling

Country Status (28)

Country Link
US (3) US7169787B2 (no)
EP (1) EP1330455B1 (no)
JP (1) JP4233322B2 (no)
KR (2) KR100837099B1 (no)
CN (1) CN1247576C (no)
AR (1) AR034269A1 (no)
AT (1) ATE301121T1 (no)
AU (2) AU2002221753B2 (no)
BG (1) BG66169B1 (no)
BR (1) BR0114903A (no)
CA (1) CA2428468C (no)
CZ (1) CZ20031146A3 (no)
DE (1) DE50106993D1 (no)
DK (1) DK1330455T3 (no)
EE (1) EE05271B1 (no)
ES (1) ES2246349T3 (no)
HK (1) HK1053839A1 (no)
HR (1) HRP20030427B1 (no)
HU (1) HUP0303034A3 (no)
IL (2) IL155386A0 (no)
MX (1) MXPA03003624A (no)
NO (1) NO324947B1 (no)
NZ (1) NZ525369A (no)
PL (1) PL213999B1 (no)
PT (1) PT1330455E (no)
SK (1) SK287774B6 (no)
TW (1) TWI262920B (no)
WO (1) WO2002034747A1 (no)

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US20040014761A1 (en) * 1997-10-28 2004-01-22 Place Virgil A. Treatment of female sexual dysfunction with phosphodiesterase inhibitors
TW200501945A (en) * 2002-11-06 2005-01-16 Celgene Corp Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases
DE10318610A1 (de) * 2003-04-24 2004-11-11 Elbion Ag 7-Azaindole und deren Verwendung als Therapeutika
US20050054691A1 (en) * 2003-08-29 2005-03-10 St. Jude Children's Research Hospital Carboxylesterase inhibitors
BRPI0414313A (pt) * 2003-09-11 2006-11-07 Kemia Inc inibidores de citocinas
JP2008503446A (ja) * 2004-05-06 2008-02-07 プレキシコン，インコーポレーテッド Ｐｄｅ４ｂ阻害剤及びその使用
MY144903A (en) 2004-06-17 2011-11-30 Novartis Ag Pyrrolopyridine derivatives and their use as crth2 antagonists
CA2583428A1 (en) * 2004-09-03 2006-03-09 Plexxikon, Inc. Bicyclic heteroaryl pde4b inhibitors
CN101355876B (zh) 2005-11-09 2012-09-05 康宾纳特克斯公司 一种适用于眼部给药的组合物
GB0525143D0 (en) 2005-12-09 2006-01-18 Novartis Ag Organic compounds
WO2007136790A2 (en) 2006-05-18 2007-11-29 Mannkind Corporation Intracellular kinase inhibitors
WO2008026687A1 (fr) 2006-09-01 2008-03-06 Kyorin Pharmaceutical Co., Ltd. Dérivé de pyrazolopyridine carboxamide et inhibiteur de phosphodiestérase (pde) comprenant le dérivé
US8012992B2 (en) 2008-06-30 2011-09-06 Allergan, Inc. Aza-indoles and related compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity
EP2344503B1 (en) * 2008-09-22 2014-04-16 Isis Innovation Ltd 5-azaindole bisphosphonates
AU2010288553A1 (en) * 2009-08-26 2012-04-12 Takeda Gmbh Methylpyrrolopyridinecarboxamides
WO2012072727A1 (en) * 2010-12-03 2012-06-07 Biotie Therapies Gmbh Crystalline modification of n-(3,5-dichloropyridin-4-yl)-[1-(4 -fluorobenzyl)-7-azaindol-3-yl)]glyoxylic acid amide as inhibitor of pde4
WO2012080329A1 (en) 2010-12-17 2012-06-21 Biotie Therapies Gmbh Formulations of n-(3,5-dichloropyridin-4-yl)-[1-(4-fluorobenzyl)-7-azaindol-3-yl)]glyoxylic acid amide
CN102584842A (zh) * 2011-01-17 2012-07-18 北京大学 取代吲哚并内酰胺衍生物的制备及作为抗疟疾剂的用途
WO2014031732A2 (en) 2012-08-22 2014-02-27 Cornell University Methods for inhibiting fascin
JP6691869B2 (ja) * 2014-02-20 2020-05-13 コーネル ユニヴァーシティー ファシンを阻害するための化合物及び方法
CN113164487A (zh) * 2018-10-12 2021-07-23 内布拉斯加大学董事委员会 磷酸二酯酶抑制剂

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GB9507297D0 (en) 1995-04-07 1995-05-31 Rh Ne Poulenc Rorer Limited New composition of matter
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AU2002221753B2 (en) 2006-12-14
US20040106641A1 (en) 2004-06-03
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US7169787B2 (en) 2007-01-30
CA2428468A1 (en) 2002-05-02
NO324947B1 (no) 2008-01-07
KR100837099B1 (ko) 2008-06-13
BG66169B1 (bg) 2011-10-31
PL362837A1 (en) 2004-11-02
KR100880586B1 (ko) 2009-01-30
CZ20031146A3 (cs) 2003-10-15
NO20031722L (no) 2003-04-14
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US20060258700A1 (en) 2006-11-16
CN1247576C (zh) 2006-03-29
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AU2175302A (en) 2002-05-06
HUP0303034A2 (hu) 2003-12-29
HUP0303034A3 (en) 2012-12-28
HRP20030427A2 (en) 2003-08-31
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AR034269A1 (es) 2004-02-18
US20080207680A1 (en) 2008-08-28
JP4233322B2 (ja) 2009-03-04
BR0114903A (pt) 2003-10-14
ATE301121T1 (de) 2005-08-15
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IL155386A (en) 2008-06-05
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