NO20023126L - Fremgangsmåte for fremstilling av citalopram - Google Patents
Fremgangsmåte for fremstilling av citalopramInfo
- Publication number
- NO20023126L NO20023126L NO20023126A NO20023126A NO20023126L NO 20023126 L NO20023126 L NO 20023126L NO 20023126 A NO20023126 A NO 20023126A NO 20023126 A NO20023126 A NO 20023126A NO 20023126 L NO20023126 L NO 20023126L
- Authority
- NO
- Norway
- Prior art keywords
- citalopram
- preparation
- formula
- diene
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/28—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/DK1999/000739 WO2001047909A1 (en) | 1999-12-28 | 1999-12-28 | Method for the preparation of citalopram |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20023126L true NO20023126L (no) | 2002-06-27 |
| NO20023126D0 NO20023126D0 (no) | 2002-06-27 |
Family
ID=8157173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20023126A NO20023126D0 (no) | 1999-12-28 | 2002-06-27 | Fremgangsmåte for fremstilling av citalopram |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6762307B2 (hu) |
| EP (1) | EP1246812B1 (hu) |
| JP (1) | JP2003519136A (hu) |
| KR (1) | KR20020073489A (hu) |
| CN (1) | CN1398263A (hu) |
| AT (1) | ATE261953T1 (hu) |
| AU (1) | AU778751B2 (hu) |
| BG (1) | BG106939A (hu) |
| CA (1) | CA2395404A1 (hu) |
| CZ (1) | CZ20022213A3 (hu) |
| DE (1) | DE69915713T2 (hu) |
| DK (1) | DK1246812T3 (hu) |
| EA (1) | EA004742B1 (hu) |
| ES (1) | ES2219095T3 (hu) |
| HU (1) | HUP0203635A3 (hu) |
| IL (1) | IL150335A0 (hu) |
| IS (1) | IS6435A (hu) |
| MX (1) | MXPA02006503A (hu) |
| NO (1) | NO20023126D0 (hu) |
| NZ (1) | NZ519739A (hu) |
| PL (1) | PL355532A1 (hu) |
| PT (1) | PT1246812E (hu) |
| SI (1) | SI1246812T1 (hu) |
| SK (1) | SK9282002A3 (hu) |
| TR (1) | TR200201678T2 (hu) |
| WO (1) | WO2001047909A1 (hu) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE237604T1 (de) * | 1999-04-14 | 2003-05-15 | Lundbeck & Co As H | Verfahren zur herstellung von citalopram |
| WO2001049672A1 (en) | 1999-12-30 | 2001-07-12 | H. Lundbeck A/S | Method for the preparation of citalopram |
| HUP0300343A2 (hu) | 2000-01-14 | 2003-06-28 | H. Lundbeck A/S | Eljárás 5-cianoftalid előállítására |
| IES20010157A2 (en) | 2000-03-03 | 2002-03-06 | Lundbeck & Co As H | Method for the preparation of citalopram |
| GB0005477D0 (en) | 2000-03-07 | 2000-04-26 | Resolution Chemicals Limited | Process for the preparation of citalopram |
| CA2402388A1 (en) | 2000-03-13 | 2001-09-20 | Hans Petersen | Method for the preparation of citalopram |
| KR20020080485A (ko) | 2000-03-13 | 2002-10-23 | 하. 룬트벡 아크티에 셀스카브 | 5-치환 1-(4-플루오로페닐)-1,3-디히드로이소벤조푸란의단계적 알킬화 |
| NL1017500C1 (nl) | 2000-03-13 | 2001-04-26 | Lundbeck & Co As H | Werkwijze voor de bereiding van Citalopram. |
| WO2001068630A1 (en) | 2000-03-14 | 2001-09-20 | H. Lundbeck A/S | Method for the preparation of citalopram |
| AR032455A1 (es) | 2000-05-12 | 2003-11-12 | Lundbeck & Co As H | Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva |
| AU2003223105A1 (en) * | 2003-03-24 | 2004-10-18 | Hetero Drugs Limited | Novel crystalline forms of (s)-citalopram oxalate |
| ITMI20040717A1 (it) * | 2004-04-09 | 2004-07-09 | Adorkem Technology Spa | Procedimento chemo-enzimatico per la preparazione dell'escitalopram |
| JP2006008603A (ja) * | 2004-06-25 | 2006-01-12 | Sumitomo Chemical Co Ltd | 光学活性シタロプラムの製造方法、その中間体およびその製造方法 |
| WO2007054105A2 (en) * | 2005-11-14 | 2007-05-18 | H. Lundbeck A/S | Method for the preparation of escitalopram |
| WO2009147687A2 (en) * | 2008-06-03 | 2009-12-10 | Shodhana Laboratories Limited | An improved process for the separation of enantiomerically pure compounds |
| US20110092719A1 (en) * | 2008-06-16 | 2011-04-21 | Shodhana Laboratories Limited | Preparation of Escitalopram, Its Salts and Intermediates |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1143703A (hu) | 1965-03-18 | |||
| GB1526331A (en) * | 1976-01-14 | 1978-09-27 | Kefalas As | Phthalanes |
| GB8419963D0 (en) | 1984-08-06 | 1984-09-12 | Lundbeck & Co As H | Intermediate compound and method |
| GB8814057D0 (en) * | 1988-06-14 | 1988-07-20 | Lundbeck & Co As H | New enantiomers & their isolation |
| US5296507A (en) | 1990-09-06 | 1994-03-22 | H.Lundbeck A/S | Treatment of cerbrovascular disorders |
| DE19626659A1 (de) | 1996-07-03 | 1998-01-08 | Basf Ag | Verfahren zur Herstellung von Phthaliden |
| DE19627697A1 (de) | 1996-07-10 | 1998-01-15 | Basf Ag | Verfahren zur Herstellung von Phthaliden |
| DE1015416T1 (de) | 1997-07-08 | 2000-10-05 | H. Lundbeck A/S, Kobenhavn-Valby | Verfahren zur herstellung von citalopram |
| UA62985C2 (en) | 1997-11-10 | 2004-01-15 | Lunnbeck As H | A method for the preparation of citalopram |
| WO1998019512A2 (en) | 1997-11-11 | 1998-05-14 | H. Lundbeck A/S | Method for the preparation of citalopram |
| NZ510858A (en) | 1998-10-20 | 2003-11-28 | H | Method for the preparation of citalopram |
| TR200101796T2 (tr) | 1998-12-23 | 2001-11-21 | H. Lundbeck A/S | 5-Siyanofitalitin preparasyonuna yönelik metot |
| AR022329A1 (es) | 1999-01-29 | 2002-09-04 | Lundbeck & Co As H | Metodo para la preparacion de 5-cianoftalida |
| ATE237604T1 (de) | 1999-04-14 | 2003-05-15 | Lundbeck & Co As H | Verfahren zur herstellung von citalopram |
| ITMI991579A1 (it) | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | Metodo per la preparazione di citalopram |
| ITMI991581A1 (it) | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | Metodo per la preparazione di citalopram |
| TR200101874T1 (tr) | 1999-10-25 | 2002-02-21 | H. Lundbeck A/S | Sitalopram hazırlanması için yöntem |
| AR026063A1 (es) | 1999-11-01 | 2002-12-26 | Lundbeck & Co As H | Metodo para la preparacion de 5-carboxiftalida. |
| US6310222B1 (en) | 1999-11-01 | 2001-10-30 | Sumika Fine Chemicals Co., Ltd. | Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate |
| WO2001049672A1 (en) | 1999-12-30 | 2001-07-12 | H. Lundbeck A/S | Method for the preparation of citalopram |
| HUP0300343A2 (hu) | 2000-01-14 | 2003-06-28 | H. Lundbeck A/S | Eljárás 5-cianoftalid előállítására |
| NL1017415C1 (nl) | 2000-02-24 | 2001-05-18 | Lundbeck & Co As H | Werkwijze voor de bereiding van Citalopram. |
| IES20010143A2 (en) | 2000-02-24 | 2001-07-25 | Lundbeck & Co As H | Method for the preparation of citalopram |
| GB0005477D0 (en) | 2000-03-07 | 2000-04-26 | Resolution Chemicals Limited | Process for the preparation of citalopram |
| FI20011622A (fi) | 2000-08-18 | 2002-02-19 | Lundbeck & Co As H | Menetelmä sitalopraamin valmistamiseksi |
| DE60105926T2 (de) | 2000-12-22 | 2005-11-24 | H. Lundbeck A/S, Valby | Verfahren zur vorbereitung von reinem citalopram |
| DE60100016T2 (de) | 2000-12-28 | 2003-04-17 | H. Lundbeck A/S, Valby | Verfahren zur herstellung von reinem citalopram |
-
1999
- 1999-12-28 NZ NZ519739A patent/NZ519739A/en unknown
- 1999-12-28 CA CA002395404A patent/CA2395404A1/en not_active Abandoned
- 1999-12-28 PT PT99962132T patent/PT1246812E/pt unknown
- 1999-12-28 AT AT99962132T patent/ATE261953T1/de not_active IP Right Cessation
- 1999-12-28 SI SI9930567T patent/SI1246812T1/xx unknown
- 1999-12-28 ES ES99962132T patent/ES2219095T3/es not_active Expired - Lifetime
- 1999-12-28 CN CN99817098A patent/CN1398263A/zh active Pending
- 1999-12-28 JP JP2001549379A patent/JP2003519136A/ja not_active Withdrawn
- 1999-12-28 AU AU18583/00A patent/AU778751B2/en not_active Ceased
- 1999-12-28 MX MXPA02006503A patent/MXPA02006503A/es not_active Application Discontinuation
- 1999-12-28 PL PL99355532A patent/PL355532A1/xx not_active Application Discontinuation
- 1999-12-28 HU HU0203635A patent/HUP0203635A3/hu unknown
- 1999-12-28 EP EP99962132A patent/EP1246812B1/en not_active Expired - Lifetime
- 1999-12-28 DK DK99962132T patent/DK1246812T3/da active
- 1999-12-28 WO PCT/DK1999/000739 patent/WO2001047909A1/en not_active Application Discontinuation
- 1999-12-28 IL IL15033599A patent/IL150335A0/xx unknown
- 1999-12-28 TR TR2002/01678T patent/TR200201678T2/xx unknown
- 1999-12-28 SK SK928-2002A patent/SK9282002A3/sk unknown
- 1999-12-28 EA EA200200719A patent/EA004742B1/ru not_active IP Right Cessation
- 1999-12-28 DE DE69915713T patent/DE69915713T2/de not_active Expired - Fee Related
- 1999-12-28 CZ CZ20022213A patent/CZ20022213A3/cs unknown
- 1999-12-28 KR KR1020027008341A patent/KR20020073489A/ko not_active Application Discontinuation
-
2002
- 2002-06-19 IS IS6435A patent/IS6435A/is unknown
- 2002-06-25 US US10/183,958 patent/US6762307B2/en not_active Expired - Fee Related
- 2002-06-27 NO NO20023126A patent/NO20023126D0/no not_active Application Discontinuation
- 2002-07-22 BG BG106939A patent/BG106939A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1246812B1 (en) | 2004-03-17 |
| KR20020073489A (ko) | 2002-09-26 |
| US20030060641A1 (en) | 2003-03-27 |
| ES2219095T3 (es) | 2004-11-16 |
| EP1246812A1 (en) | 2002-10-09 |
| TR200201678T2 (tr) | 2002-10-21 |
| EA200200719A1 (ru) | 2002-12-26 |
| BG106939A (en) | 2003-03-31 |
| SI1246812T1 (en) | 2004-08-31 |
| WO2001047909A1 (en) | 2001-07-05 |
| JP2003519136A (ja) | 2003-06-17 |
| PL355532A1 (en) | 2004-05-04 |
| SK9282002A3 (en) | 2002-11-06 |
| DE69915713D1 (de) | 2004-04-22 |
| HUP0203635A2 (hu) | 2003-02-28 |
| DK1246812T3 (da) | 2004-07-05 |
| US6762307B2 (en) | 2004-07-13 |
| EA004742B1 (ru) | 2004-08-26 |
| CZ20022213A3 (cs) | 2002-09-11 |
| MXPA02006503A (es) | 2002-12-09 |
| NO20023126D0 (no) | 2002-06-27 |
| NZ519739A (en) | 2004-03-26 |
| IL150335A0 (en) | 2002-12-01 |
| CN1398263A (zh) | 2003-02-19 |
| DE69915713T2 (de) | 2005-03-03 |
| PT1246812E (pt) | 2004-08-31 |
| CA2395404A1 (en) | 2001-07-05 |
| AU778751B2 (en) | 2004-12-16 |
| HUP0203635A3 (en) | 2005-02-28 |
| AU1858300A (en) | 2001-07-09 |
| IS6435A (is) | 2002-06-19 |
| ATE261953T1 (de) | 2004-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |