NO20012782L - Mikroniserte eplerenon sammensetninger - Google Patents
Mikroniserte eplerenon sammensetningerInfo
- Publication number
- NO20012782L NO20012782L NO20012782A NO20012782A NO20012782L NO 20012782 L NO20012782 L NO 20012782L NO 20012782 A NO20012782 A NO 20012782A NO 20012782 A NO20012782 A NO 20012782A NO 20012782 L NO20012782 L NO 20012782L
- Authority
- NO
- Norway
- Prior art keywords
- micronized eplerenone
- compositions
- eplerenone compositions
- micronized
- eplerenone
- Prior art date
Links
- JUKPWJGBANNWMW-VWBFHTRKSA-N eplerenone Chemical compound C([C@@H]1[C@]2(C)C[C@H]3O[C@]33[C@@]4(C)CCC(=O)C=C4C[C@H]([C@@H]13)C(=O)OC)C[C@@]21CCC(=O)O1 JUKPWJGBANNWMW-VWBFHTRKSA-N 0.000 title 1
- 229960001208 eplerenone Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11164698P | 1998-12-09 | 1998-12-09 | |
| PCT/US1999/029136 WO2000033847A1 (en) | 1998-12-09 | 1999-12-08 | Micronized eplerenone compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20012782D0 NO20012782D0 (no) | 2001-06-06 |
| NO20012782L true NO20012782L (no) | 2001-07-03 |
Family
ID=22339668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20012782A NO20012782L (no) | 1998-12-09 | 2001-06-06 | Mikroniserte eplerenon sammensetninger |
Country Status (30)
| Country | Link |
|---|---|
| US (7) | US6410054B1 (cs) |
| EP (1) | EP1135139B1 (cs) |
| JP (1) | JP2002531508A (cs) |
| KR (1) | KR100671275B1 (cs) |
| CN (1) | CN1230179C (cs) |
| AR (1) | AR028982A1 (cs) |
| AT (1) | ATE249223T1 (cs) |
| AU (1) | AU763166B2 (cs) |
| BR (1) | BR9915964A (cs) |
| CA (1) | CA2326842A1 (cs) |
| CZ (1) | CZ20011942A3 (cs) |
| DE (1) | DE69911240T2 (cs) |
| DK (1) | DK1135139T3 (cs) |
| EA (1) | EA003266B1 (cs) |
| ES (1) | ES2207977T3 (cs) |
| HK (1) | HK1041641B (cs) |
| HU (1) | HU224428B1 (cs) |
| ID (1) | ID30115A (cs) |
| IL (1) | IL143301A0 (cs) |
| IS (1) | IS2325B (cs) |
| MY (1) | MY125651A (cs) |
| NO (1) | NO20012782L (cs) |
| NZ (1) | NZ511869A (cs) |
| PL (1) | PL198425B1 (cs) |
| PT (1) | PT1135139E (cs) |
| TR (1) | TR200101643T2 (cs) |
| TW (1) | TWI234459B (cs) |
| UA (1) | UA74141C2 (cs) |
| WO (1) | WO2000033847A1 (cs) |
| ZA (1) | ZA200104361B (cs) |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA74141C2 (uk) * | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
| ES2240209T3 (es) * | 1999-12-08 | 2005-10-16 | Pharmacia Corporation | Composiciones de eplerenona nanoparticulada. |
| EP1527782A1 (en) * | 1999-12-08 | 2005-05-04 | Pharmacia Corporation | Nanoparticulate eplerenone compositions |
| US20020132001A1 (en) * | 2000-05-11 | 2002-09-19 | Garthwaite Susan M. | Aldosterone antagonist composition for release during aldosterone acrophase |
| CA2416152A1 (en) * | 2000-07-27 | 2002-02-07 | Pharmacia Corporation | Aldosterone blocker therapy to prevent or treat inflammation-related disorders |
| CA2415789A1 (en) * | 2000-07-27 | 2002-02-07 | Pharmacia Corporation | Epoxy-steroidal aldosterone antagonist and beta-adrenergic antagonist combination therapy for treatment of congestive heart failure |
| DE60114027T2 (de) * | 2000-08-28 | 2006-07-13 | Pharmacia Corp. | Verwendung von einem aldosteron-rezeptor-antagonisten zur verbesserung der kognitiven funktion |
| US8168616B1 (en) * | 2000-11-17 | 2012-05-01 | Novartis Ag | Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension |
| ATE303399T1 (de) | 2001-03-12 | 2005-09-15 | Intercept Pharmaceuticals Inc | Steroide als agonisten für fxr |
| US20040173146A1 (en) * | 2001-06-07 | 2004-09-09 | Figueroa Iddys D. | Application of a bioactive agent to a delivery substrate |
| US20040173147A1 (en) * | 2001-06-07 | 2004-09-09 | Figueroa Iddys D. | Application of a bioactive agent to a delivery substrate |
| US6962715B2 (en) * | 2001-10-24 | 2005-11-08 | Hewlett-Packard Development Company, L.P. | Method and dosage form for dispensing a bioactive substance |
| GB0114532D0 (en) * | 2001-06-14 | 2001-08-08 | Jagotec Ag | Novel compositions |
| AP2004002951A0 (en) * | 2001-07-19 | 2004-03-31 | Pharmacia Corp | "Combination of Eplerenone and an HMG CoA Reductase Inhibitor". |
| AU2002249804A1 (en) * | 2001-12-13 | 2003-06-30 | Pharmacia Corporation | Methods for treatment or prophylaxis of aldosterone-mediated pathogenic effects in a subject using an epoxy-steroidal aldosterone antagonist |
| JP2005521665A (ja) * | 2002-01-30 | 2005-07-21 | ファルマシア・コーポレーション | 心血管障害の予防および治療のための、アルドステロンアンタゴニストおよび非ステロイド系抗炎症剤の併用治療 |
| KR101002374B1 (ko) * | 2002-02-26 | 2010-12-17 | 아스트라제네카 아베 | 수용성 셀룰로스 유도체를 포함하는 이레사의 약학 조제물 |
| MXPA04009037A (es) * | 2002-03-20 | 2005-01-25 | Pharmacia Corp | Formulacion de eplerenona de almacenamiento estable. |
| US7235655B2 (en) * | 2002-03-22 | 2007-06-26 | Pharmacia & Upjohn Company | Processes to prepare eplerenone |
| NZ548754A (en) * | 2002-04-26 | 2008-06-30 | Schering Aktiengellschaft | Treatment of hypertension in women receiving hormone replacement therapy |
| AU2003259979A1 (en) * | 2002-08-23 | 2004-03-11 | Pharmacia Corporation | Modulation of matrix metalloproteinase (mmp) activity with aldosterone blocker(s) |
| AU2003279070A1 (en) * | 2002-09-30 | 2004-04-23 | Acusphere Inc | Sustained release porous microparticles for inhalation |
| ATE454155T1 (de) * | 2002-11-05 | 2010-01-15 | Bayer Schering Pharma Ag | Verwendung von drospirenon zur behandlung von hypertension |
| US7786101B2 (en) * | 2002-11-05 | 2010-08-31 | Bayer Schering Pharma Ag | Cardiovascular protection using anti-aldosteronic progestins |
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| US5529992A (en) * | 1992-04-21 | 1996-06-25 | Curators Of The University Of Missouri | Method for inhibiting myocardial fibrosis by administering an aldosterone antagonist which suppresses aldoster one receptors |
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-
1999
- 1999-08-12 UA UA2001063853A patent/UA74141C2/uk unknown
- 1999-12-07 AR ARP990106255A patent/AR028982A1/es not_active Application Discontinuation
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- 1999-12-08 DK DK99963052T patent/DK1135139T3/da active
- 1999-12-08 CN CNB998141100A patent/CN1230179C/zh not_active Expired - Fee Related
- 1999-12-08 BR BR9915964-3A patent/BR9915964A/pt not_active Application Discontinuation
- 1999-12-08 JP JP2000586339A patent/JP2002531508A/ja active Pending
- 1999-12-08 AT AT99963052T patent/ATE249223T1/de active
- 1999-12-08 EA EA200100519A patent/EA003266B1/ru not_active IP Right Cessation
- 1999-12-08 WO PCT/US1999/029136 patent/WO2000033847A1/en not_active Ceased
- 1999-12-08 DE DE69911240T patent/DE69911240T2/de not_active Expired - Lifetime
- 1999-12-08 IL IL14330199A patent/IL143301A0/xx not_active IP Right Cessation
- 1999-12-08 MY MYPI99005328A patent/MY125651A/en unknown
- 1999-12-08 HU HU0104718A patent/HU224428B1/hu not_active IP Right Cessation
- 1999-12-08 EP EP99963052A patent/EP1135139B1/en not_active Expired - Lifetime
- 1999-12-08 AU AU19368/00A patent/AU763166B2/en not_active Expired
- 1999-12-08 CA CA002326842A patent/CA2326842A1/en not_active Abandoned
- 1999-12-08 HK HK02103113.4A patent/HK1041641B/zh unknown
- 1999-12-08 ID IDW00200101191A patent/ID30115A/id unknown
- 1999-12-08 TR TR2001/01643T patent/TR200101643T2/xx unknown
- 1999-12-08 ES ES99963052T patent/ES2207977T3/es not_active Expired - Lifetime
- 1999-12-08 PL PL349632A patent/PL198425B1/pl not_active IP Right Cessation
- 1999-12-08 PT PT99963052T patent/PT1135139E/pt unknown
- 1999-12-08 CZ CZ20011942A patent/CZ20011942A3/cs unknown
- 1999-12-08 KR KR1020017007041A patent/KR100671275B1/ko not_active Expired - Fee Related
- 1999-12-08 US US09/456,614 patent/US6410054B1/en not_active Expired - Lifetime
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2000
- 2000-02-22 TW TW088121495A patent/TWI234459B/zh not_active IP Right Cessation
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2001
- 2001-05-25 IS IS5953A patent/IS2325B/is unknown
- 2001-05-28 ZA ZA200104361A patent/ZA200104361B/en unknown
- 2001-06-06 NO NO20012782A patent/NO20012782L/no unknown
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2002
- 2002-01-31 US US10/066,360 patent/US6592902B2/en not_active Expired - Lifetime
- 2002-03-19 US US10/100,712 patent/US6558707B1/en not_active Expired - Lifetime
- 2002-03-19 US US10/100,930 patent/US6534093B1/en not_active Expired - Lifetime
- 2002-03-19 US US10/101,361 patent/US6495165B1/en not_active Expired - Lifetime
- 2002-11-06 US US10/289,025 patent/US6863902B2/en not_active Expired - Fee Related
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