NO20012571L - Reaktiv krystalliseringsmetode for å forbedre partikkelstörrelsen - Google Patents

Reaktiv krystalliseringsmetode for å forbedre partikkelstörrelsen

Info

Publication number
NO20012571L
NO20012571L NO20012571A NO20012571A NO20012571L NO 20012571 L NO20012571 L NO 20012571L NO 20012571 A NO20012571 A NO 20012571A NO 20012571 A NO20012571 A NO 20012571A NO 20012571 L NO20012571 L NO 20012571L
Authority
NO
Norway
Prior art keywords
particle size
crystallization method
improve particle
reactive crystallization
product
Prior art date
Application number
NO20012571A
Other languages
English (en)
Norwegian (no)
Other versions
NO20012571D0 (no
Inventor
David Jon Am Ende
Thomas Charles Crawford
Neil Philip Weston
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20012571D0 publication Critical patent/NO20012571D0/no
Publication of NO20012571L publication Critical patent/NO20012571L/no

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/02—Crystallisation from solutions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/20—Jet mixers, i.e. mixers using high-speed fluid streams
    • B01F25/23—Mixing by intersecting jets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J14/00—Chemical processes in general for reacting liquids with liquids; Apparatus specially adapted therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/18—Stationary reactors having moving elements inside
    • B01J19/1806—Stationary reactors having moving elements inside resulting in a turbulent flow of the reactants, such as in centrifugal-type reactors, or having a high Reynolds-number
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/26—Nozzle-type reactors, i.e. the distribution of the initial reactants within the reactor is effected by their introduction or injection through nozzles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00—Other general methods
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00051—Controlling the temperature
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00051—Controlling the temperature
    • B01J2219/00074—Controlling the temperature by indirect heating or cooling employing heat exchange fluids
    • B01J2219/00087—Controlling the temperature by indirect heating or cooling employing heat exchange fluids with heat exchange elements outside the reactor
    • B01J2219/00101—Reflux columns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00164—Controlling or regulating processes controlling the flow
NO20012571A 2000-05-26 2001-05-25 Reaktiv krystalliseringsmetode for å forbedre partikkelstörrelsen NO20012571L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20762900P 2000-05-26 2000-05-26

Publications (2)

Publication Number Publication Date
NO20012571D0 NO20012571D0 (no) 2001-05-25
NO20012571L true NO20012571L (no) 2001-11-27

Family

ID=22771343

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012571A NO20012571L (no) 2000-05-26 2001-05-25 Reaktiv krystalliseringsmetode for å forbedre partikkelstörrelsen

Country Status (38)

Country Link
US (1) US6558435B2 (sh)
EP (1) EP1157726A1 (sh)
JP (1) JP2002028475A (sh)
KR (1) KR100408949B1 (sh)
CN (1) CN1183989C (sh)
AP (1) AP1321A (sh)
AR (1) AR029099A1 (sh)
AU (1) AU775613B2 (sh)
BG (1) BG105518A (sh)
BR (1) BR0102129A (sh)
CA (1) CA2349136A1 (sh)
CZ (1) CZ20011726A3 (sh)
DZ (1) DZ3075A1 (sh)
EA (1) EA003261B1 (sh)
EC (1) ECSP014083A (sh)
EE (1) EE200100284A (sh)
GE (1) GEP20043173B (sh)
GT (1) GT200100095A (sh)
HK (1) HK1038896B (sh)
HR (1) HRP20010399A2 (sh)
ID (1) ID30368A (sh)
IL (1) IL143227A (sh)
IS (1) IS5950A (sh)
MA (1) MA25321A1 (sh)
NO (1) NO20012571L (sh)
NZ (1) NZ511966A (sh)
OA (1) OA11719A (sh)
PA (1) PA8517001A1 (sh)
PE (1) PE20020149A1 (sh)
PL (1) PL347736A1 (sh)
SG (1) SG96223A1 (sh)
SK (1) SK6882001A3 (sh)
SV (1) SV2001000464A (sh)
TN (1) TNSN01075A1 (sh)
TR (1) TR200101453A2 (sh)
TW (1) TWI236930B (sh)
YU (1) YU34501A (sh)
ZA (1) ZA200104207B (sh)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ME00466B (me) * 2001-05-14 2011-10-10 Pfizer Prod Inc Tartaratne soli 5,8,14-triazatetraciklo( 10.3.1.02,11.04,9)-heksadeka-2 (11),3,5,7,9-pentaena
CA2468705A1 (en) * 2001-11-29 2003-06-05 Pfizer Products Inc. Succinic acid salts of 5,8,14-triazatetracyclo'10.3.1.0<2,11>.0<4,9>-hexadeca-2(11),3,5,7,9-pentaene and pharmaceutical compositions thereof
BR0309625A (pt) * 2002-04-29 2005-03-08 Bristol Myers Squibb Co Sistema de cristalização que utiliza atomização
KR20050007534A (ko) * 2002-05-10 2005-01-19 브리스톨-마이어스 스큅 컴퍼니 균질화를 이용한 결정화 시스템
US20040098839A1 (en) * 2002-11-27 2004-05-27 Pfizer Inc. Crystallization method and apparatus using an impinging plate assembly
WO2004050655A1 (en) * 2002-12-04 2004-06-17 Dr. Reddy's Laboratories Limited Polymorphic forms of ziprasidone and its hydrochloride
US7488729B2 (en) 2002-12-04 2009-02-10 Dr. Reddy's Laboratories Limited Polymorphic forms of ziprasidone and its hydrochloride salt and process for preparation thereof
CA2528192A1 (en) * 2003-06-03 2005-02-24 Teva Pharmaceutical Industries Ltd Cristalline ziprasidone hcl and processes for preparation thereof
TWI371274B (en) 2003-10-23 2012-09-01 Bristol Myers Squibb Co Process for making sterile aripiprazole of desired mean particle size
US7667037B2 (en) 2003-10-24 2010-02-23 Teva Pharmaceutical Industries Ltd. Processes for preparation of ziprasidone
EP1703898A2 (en) * 2003-12-31 2006-09-27 Alpharma, Inc. Ziprasidone formulations
US20050256314A1 (en) * 2004-05-04 2005-11-17 Soojin Kim Process employing controlled crystallization in forming crystals of a pharmaceutical
US7829720B2 (en) 2004-05-04 2010-11-09 Bristol-Myers Squibb Company Process for preparing atazanavir bisulfate and novel forms
US7396932B2 (en) * 2004-09-28 2008-07-08 Bristol-Myers Squibb Company Process for preparing 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
US7314516B2 (en) * 2004-12-29 2008-01-01 Five Star Technologies, Inc. Hydrodynamic cavitation crystallization device and process
US20060160841A1 (en) * 2005-01-19 2006-07-20 Chenkou Wei Crystallization via high-shear transformation
DE102005053862A1 (de) 2005-11-04 2007-05-10 Pharmasol Gmbh Verfahren und Vorrichtung zur Herstellung hochfeiner Partikel sowie zur Beschichtung solcher Partikel
CA2640922A1 (en) 2006-02-01 2007-11-22 Medichem, S.A. Process for preparing voriconazole, new polymorphic form of intermediate thereof, and uses thereof
US20080193518A1 (en) * 2006-04-28 2008-08-14 Schering Corporation Process for the precipitation and isolation of 6,6-Dimethyl-3-Aza Bicyclo [3.1.0] Hexane-Amide compounds by controlled precipitation and pharmaceutical formulations containing same
US8420122B2 (en) * 2006-04-28 2013-04-16 Merck Sharp & Dohme Corp. Process for the precipitation and isolation of 6,6-dimethyl-3-aza-bicyclo [3.1.0] hexane-amide compounds by controlled precipitation and pharmaceutical formulations containing same
CN101495095B (zh) * 2006-04-28 2013-05-29 默沙东公司 通过受控的沉淀来沉淀和分离6,6-二甲基-3-氮杂-双环[3.1.0]己烷-酰胺化合物的方法和含有其的药学制剂
KR100850010B1 (ko) * 2007-03-19 2008-08-04 희성금속 주식회사 초음파 화학적 반응에 의한 산화 인듐 분말의 제조방법 및ｉｔｏ 타겟재의 제조방법
KR100850011B1 (ko) * 2007-03-19 2008-08-04 희성금속 주식회사 초음파 화학적 반응에 의한 산화 주석 분말의 제조 방법 및ｉｔｏ 타겟재의 제조 방법
US20100183715A1 (en) * 2007-06-22 2010-07-22 Bristo-Meyers Squibb Company Tableted compositions containing atazanavir
EP2178513B1 (en) * 2007-06-22 2011-03-30 Bristol-Myers Squibb Company Tableted compositions containing atazanavir
ATE500820T1 (de) * 2007-06-22 2011-03-15 Bristol Myers Squibb Co Tablettierte atazanavirhaltige zusammensetzungen
WO2009002823A2 (en) * 2007-06-22 2008-12-31 Bristol-Myers Squibb Company Tableted compositions containing atazanavir
EP2197446A4 (en) * 2007-08-31 2012-01-25 Reddys Lab Ltd Dr PREPARATION OF HYDROCHLORIDE OF ZIPRASIDONE MONOHYDRATE
WO2009101185A2 (en) * 2008-02-15 2009-08-20 Medichem, S.A. A NEW POLYMORPHIC FORM OF A PYRAZINO[2,3-h][3] BENZAZEPINE DERIVATIVE
WO2009111623A2 (en) * 2008-03-06 2009-09-11 Dr. Reddy's Laboratories Ltd. Amorphous varenicline tartrate
US8187554B2 (en) 2008-04-23 2012-05-29 Microfluidics International Corporation Apparatus and methods for nanoparticle generation and process intensification of transport and reaction systems
EP2268639A2 (en) 2008-05-22 2011-01-05 Teva Pharmaceutical Industries Ltd. Varenicline tosylate, an intermediate in the preparation process of varenicline l-tartrate
US20090318695A1 (en) * 2008-06-19 2009-12-24 Vinod Kumar Kansal Processes for the preparation of varenicline and intermediates thereof
US8219740B2 (en) * 2008-06-25 2012-07-10 International Business Machines Corporation Flash sector seeding to reduce program times
US20100010221A1 (en) * 2008-07-10 2010-01-14 Revital Lifshitz-Liron Processes for purifying varenicline l-tartrate salt and preparing crystalline forms of varenicline l-tartrate salt
DE102009008478A1 (de) 2009-02-11 2010-08-19 PHAST Gesellschaft für pharmazeutische Qualitätsstandards mbH Vorrichtung und Verfahren zur Herstellung pharmazeutisch hochfeiner Partikel sowie zur Beschichtung solcher Partikel in Mikroreaktoren
RU2012102052A (ru) 2009-06-22 2013-11-20 Тева Фармасьютикал Индастриз Лтд. Твердые формы солей варениклина и способы их получения
MTP4285B (en) 2009-12-30 2011-07-04 Medichem Sa A 1-(1h-1,2,3-triazol-1-yl)butan-2-ol derivative for pharmaceutical use, and the use of a 1-(1h-1, 2, 4- triazol-1yl) butan-2-ol derivative with substially undefined crystal shap for preparing said 1-(1h-1, 2, 4-triazol-1-yl0 butan-2-ol derivative
EP2545054A1 (en) * 2010-03-09 2013-01-16 Actavis Group Ptc Ehf Highly pure varenicline or a pharmaceutically acceptable salt thereof substantially free of methylvarenicline impurity
WO2011116763A1 (de) 2010-03-22 2011-09-29 Mjr Pharmjet Gmbh Verfahren und vorrichtung zur herstellung von mikro- oder nanopartikeln
WO2011140431A1 (en) 2010-05-06 2011-11-10 Teva Pharmaceutical Industries Ltd. Varenicline salts and crystal forms thereof
BR112013003705B1 (pt) 2010-09-28 2020-02-04 Dow Global Technologies Llc conduto de mistura, misturador estático e método para misturar
US10350556B2 (en) 2011-01-07 2019-07-16 Microfluidics International Corporation Low holdup volume mixing chamber
US9079140B2 (en) 2011-04-13 2015-07-14 Microfluidics International Corporation Compact interaction chamber with multiple cross micro impinging jets
US9199209B2 (en) 2011-04-13 2015-12-01 Microfluidics International Corporation Interaction chamber with flow inlet optimization
US9732068B1 (en) 2013-03-15 2017-08-15 GenSyn Technologies, Inc. System for crystalizing chemical compounds and methodologies for utilizing the same
CN106132496B (zh) * 2014-03-19 2020-03-13 巴斯夫欧洲公司 用于将物质从溶液中分离出来的方法和装置
CN104843745B (zh) * 2015-04-27 2016-08-24 青海国泰盐湖化肥有限公司 一种复分解法硝酸钾产品粒度的控制方法
CN106853295A (zh) * 2015-12-09 2017-06-16 北大方正集团有限公司 一种基于膜分散的结晶方法
CN108264457A (zh) * 2017-01-04 2018-07-10 辽宁药联制药有限公司 一种醋酸钾的制备方法
JP7320852B2 (ja) 2018-06-22 2023-08-04 デルファイ サイエンティフィック、エルエルシー ナノ材料及び高純度化学物質を連続製造する装置、システム、及び方法
CN111346397B (zh) * 2020-03-11 2022-03-29 天津大学 适用于溶析结晶或反应结晶的加料设备
CN113980020B (zh) * 2021-11-22 2023-05-09 浙江车头制药股份有限公司 一种酒石酸伐尼克兰晶型的制备方法
CN114130324A (zh) * 2021-12-01 2022-03-04 沈阳铝镁设计研究院有限公司 一种蛟吸增效分解系统

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3330445A1 (de) * 1983-08-24 1985-03-21 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von als feststoffe anfallenden chemischen verbindungen aus fluessigen ausgangsstoffen
US4675194A (en) * 1986-03-03 1987-06-23 Reaction Technology, Inc. Sonic process for converting proteinaceous raw materials in situ into semi-solid food products
SE8700213L (sv) 1987-01-21 1988-07-22 Nobel Kemi Ab Sett att framstella kristallina substanser
CH671166A5 (en) 1987-07-01 1989-08-15 Fershan Holding S A Crystallisation nuclei formation - by turbulising soln. and applying mechanical energy to form nucleation sites
CA2044706C (en) 1990-06-15 2003-02-25 Michael Midler Jr. Crystallization method to improve crystal structure and size
US5143965A (en) * 1990-12-26 1992-09-01 The Dow Chemical Company Magnesium hydroxide having fine, plate-like crystalline structure and process therefor
GB9313642D0 (en) 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
US5853691A (en) * 1993-08-10 1998-12-29 State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On The Behalf Of The University Of Oregon Silver halides of altered crystal habit or morphology and methods for producing same
GB9413202D0 (en) 1994-06-30 1994-08-24 Univ Bradford Method and apparatus for the formation of particles
DE4431872C1 (de) 1994-09-07 1996-01-11 Santrade Ltd Anwendung von Ultraschall bei der Verfestigung von Schmelzen oder übersättigten Lösungen auf Förderbändern oder Aufnahmetrommeln
SE9501384D0 (sv) 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
GB9624615D0 (en) 1996-11-26 1997-01-15 Zeneca Ltd Chrystallisation process
GB9703673D0 (en) 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles

Also Published As

Publication number Publication date
PA8517001A1 (es) 2002-09-30
KR100408949B1 (ko) 2003-12-06
TWI236930B (en) 2005-08-01
CA2349136A1 (en) 2001-11-26
EA200100473A1 (ru) 2002-02-28
HRP20010399A2 (en) 2002-12-31
CZ20011726A3 (cs) 2002-02-13
AP1321A (en) 2004-10-27
TR200101453A3 (tr) 2001-12-21
IL143227A (en) 2005-06-19
US20020016498A1 (en) 2002-02-07
BG105518A (en) 2001-12-31
BR0102129A (pt) 2002-05-21
AU4805601A (en) 2001-12-13
IL143227A0 (en) 2002-04-21
SV2001000464A (es) 2001-07-03
OA11719A (en) 2005-01-26
ID30368A (id) 2001-11-29
ECSP014083A (es) 2003-01-13
TNSN01075A1 (fr) 2005-11-10
EP1157726A1 (en) 2001-11-28
NZ511966A (en) 2002-11-26
AU775613B2 (en) 2004-08-05
TR200101453A2 (tr) 2001-12-21
NO20012571D0 (no) 2001-05-25
PL347736A1 (en) 2001-12-03
AP2001002151A0 (en) 2001-06-30
AR029099A1 (es) 2003-06-04
MA25321A1 (fr) 2001-12-31
CN1183989C (zh) 2005-01-12
CN1326803A (zh) 2001-12-19
KR20010107750A (ko) 2001-12-07
PE20020149A1 (es) 2002-02-26
US6558435B2 (en) 2003-05-06
GEP20043173B (en) 2004-02-25
IS5950A (is) 2001-11-26
DZ3075A1 (fr) 2004-09-14
GT200100095A (es) 2003-12-12
ZA200104207B (en) 2002-11-25
JP2002028475A (ja) 2002-01-29
SK6882001A3 (en) 2002-04-04
EA003261B1 (ru) 2003-02-27
SG96223A1 (en) 2003-05-23
EE200100284A (et) 2002-02-15
YU34501A (sh) 2003-10-31
HK1038896B (zh) 2005-05-06
HK1038896A1 (en) 2002-04-04

Similar Documents

Publication Publication Date Title
NO20012571L (no) Reaktiv krystalliseringsmetode for å forbedre partikkelstörrelsen
CA2447474A1 (en) Processes and apparatus for quantitatively converting urea to ammonia on demand
WO2006062403A3 (en) Process for the production of synthesis gas and reactor for such process
MY121013A (en) Method for producing acrylic acid and methacrylic acid
GEP19991647B (en) Method for Production of Methyl N-N-(3,3-dimethyl-butil)-L-a-Aspartil-L-Phenilalanin Ester
WO2004094569A3 (en) Urea based composition and system for same
WO2000001615A8 (en) Method and apparatus for the preparation of high purity phosphine or other gas
AU2001270085A1 (en) Foam and method of making
WO2003057818A3 (en) Process and apparatus for performing a gas-sparged reaction
JPS6424094A (en) Synthesizing apparatus for diamond
WO2002083817A3 (en) Cobalt catalyst activation process
CA2205870A1 (en) A process and device for producing foam using carbon dioxide dissolved under pressure
CA2315618A1 (en) Process for production of hydrogen peroxide
WO2003045543A3 (en) Process for enhancing the kinetics of hydrogenation/dehydrogenation of ma1h4 and mbh4 metal hydrides for reversible hydrogen storage
WO2004022269A3 (en) Method and apparatus for controlling the size of powder produced by the armstrong process
AU2660988A (en) A process for the production of solid or paste-form products
ATE373516T1 (de) Mikrowellenreaktor und verfahren zur steuerung von reaktionen von aktivierten molekülen
WO2004047797A8 (en) Crystallization method and apparatus using an impinging plate assembly
WO2002083988A3 (en) Micro-engineered reactors
CA2112918A1 (en) Process for the Preparation of Aluminoxanes
AU7433100A (en) Process for the preparation of diazomethane
MY129700A (en) Method for producing polyacrylic acid
ATE329900T1 (de) Verfahren zur herstellung von 2-pyrrolidon
EP1160307A3 (de) Verfahren und Vorrichtung zur thermischen Behandlung und chemischen Umsetzung von Natur- und Synthesestoffen unter Zeugen eines Produktgases zur weiteren Verwendung
CA2428339A1 (en) Process for producing synthesis gas by non-catalytic partial oxidation of natural gas

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application