NO20012228L - CRF-reseptorantagonister og tilhörende fremgangsmåter - Google Patents

CRF-reseptorantagonister og tilhörende fremgangsmåter

Info

Publication number
NO20012228L
NO20012228L NO20012228A NO20012228A NO20012228L NO 20012228 L NO20012228 L NO 20012228L NO 20012228 A NO20012228 A NO 20012228A NO 20012228 A NO20012228 A NO 20012228A NO 20012228 L NO20012228 L NO 20012228L
Authority
NO
Norway
Prior art keywords
receptor antagonists
associated methods
crf receptor
compounds
treatment
Prior art date
Application number
NO20012228A
Other languages
English (en)
Norwegian (no)
Other versions
NO20012228D0 (no
Inventor
Mustapha Haddach
Zhiqiang Guo
James R Mccarthy
Original Assignee
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
Publication of NO20012228D0 publication Critical patent/NO20012228D0/no
Publication of NO20012228L publication Critical patent/NO20012228L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems
NO20012228A 1998-11-12 2001-05-04 CRF-reseptorantagonister og tilhörende fremgangsmåter NO20012228L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19095898A 1998-11-12 1998-11-12
US40074499A 1999-09-21 1999-09-21
PCT/US1999/026984 WO2000027850A2 (en) 1998-11-12 1999-11-12 Crf receptor antagonists and methods relating thereto

Publications (2)

Publication Number Publication Date
NO20012228D0 NO20012228D0 (no) 2001-05-04
NO20012228L true NO20012228L (no) 2001-05-04

Family

ID=26886600

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012228A NO20012228L (no) 1998-11-12 2001-05-04 CRF-reseptorantagonister og tilhörende fremgangsmåter

Country Status (19)

Country Link
US (3) US6348466B1 (de)
EP (1) EP1129096B1 (de)
JP (1) JP2002529469A (de)
KR (1) KR20010080402A (de)
CN (1) CN1178941C (de)
AT (1) ATE240958T1 (de)
AU (1) AU755997B2 (de)
BR (1) BR9915129A (de)
CA (1) CA2349904A1 (de)
DE (1) DE69908173T2 (de)
DK (1) DK1129096T3 (de)
ES (1) ES2196898T3 (de)
HK (1) HK1038925B (de)
IL (1) IL143105A0 (de)
NO (1) NO20012228L (de)
NZ (1) NZ511267A (de)
PT (1) PT1129096E (de)
TR (1) TR200102178T2 (de)
WO (1) WO2000027850A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001058489A1 (fr) * 2000-02-14 2001-08-16 Japan Tobacco Inc. Agents prophylactiques/therapeutiques contre le stress postoperatoire
CA2407597A1 (en) * 2000-05-01 2001-11-08 Dupont Pharmaceuticals Company Tricyclic fused pyridine and pyrimidine derivatives as crf receptor antagonists
US6541469B2 (en) 2000-05-18 2003-04-01 Neurocrine Biosciences, Inc. CRF receptor antagonists and methods relating thereto
AU2001261850A1 (en) 2000-05-18 2001-11-26 Neurocrine Biosciences, Inc. Crf receptor antagonists and methods relating thereto
DE60126134T2 (de) 2000-11-03 2007-10-18 Neurocrine Biosciences, Inc., San Diego CRF-Rezeptorantagonisten und Verfahren, die damit in Beziehung stehen
ATE526330T1 (de) 2000-12-28 2011-10-15 Ono Pharmaceutical Co Heterotrizyklische verbindungen als antagonisten des crf-rezeptors
US6583143B2 (en) 2000-12-28 2003-06-24 Neurocrine Biosciences, Inc. CRF receptor antagonists and methods relating thereto
EP1383498B1 (de) 2001-04-30 2006-03-15 Glaxo Group Limited Crf receptor antagonisten
GB0117395D0 (en) * 2001-07-17 2001-09-05 Glaxo Group Ltd Chemical compounds
US7273871B2 (en) 2001-07-17 2007-09-25 Sb Pharmco Puerto Rico Inc. Phenyl-5,6,6A,7,8,9-hexahydro-4H-1,4,9-triaza-phenalene derivatives as CRF antagonists
BRPI0411923A (pt) 2003-06-25 2006-08-15 Ono Pharmaceutical Co sal de ácido metanossulfÈnico de composto pirazolopirimidina, cristal do mesmo e processo de produção do mesmo
US20060024661A1 (en) * 2003-07-30 2006-02-02 The Regents Of The University Of California Modulation of CRF potentiation of NMDA receptor currents via CRF receptor 2
WO2005063749A1 (en) * 2003-12-22 2005-07-14 Sb Pharmco Puerto Rico Inc Crf receptor antagonists and methods relating thereto
AU2005250056A1 (en) 2004-06-03 2005-12-15 Athlomics Pty Ltd Agents and methods for diagnosing stress
US7869958B2 (en) * 2004-08-09 2011-01-11 Research Development Foundation Structure-based modulators of B1 G-protein coupled receptors
WO2007050087A1 (en) 2004-08-25 2007-05-03 Ardea Biosciences, Inc. N[S(4-aryl-triazol-3-yl)α -mercaptoacetyl]-p-amino benozoic acids AS HIV REVERSE TRANSCRIPTASE INHIBITORS
ES2374773T3 (es) 2004-08-25 2012-02-21 Ardea Biosciences, Inc. S-triazolil alfa-mercaptoacetanilidas como inhibidores de la transcriptasa inversa del vih.
EP1877411B9 (de) 2005-05-05 2012-08-29 Ardea Biosciences, Inc. Diaryl-purin, azapurine und deazapurine als nichtnukleoside reverse-transkriptase-inhibitoren zur behandlung von hiv
MX2009005009A (es) 2006-11-09 2009-09-22 Ardea Biosciences Inc Compuestos heterociclicos biciclicos 4-cianofenilamino sustituidos como inhibidores del virus de inmunodeficiencia humana.
EP2217577B1 (de) 2007-11-27 2014-08-06 Ardea Biosciences, Inc. Neue verbindungen und zusammensetzungen sowie ihre verwendung
CA2709176C (en) 2007-12-14 2013-02-05 Ardea Biosciences, Inc. Reverse transcriptase inhibitors

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4605642A (en) 1984-02-23 1986-08-12 The Salk Institute For Biological Studies CRF antagonists
US5013737A (en) * 1988-02-22 1991-05-07 American Cyanamid Company 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones
US4904658A (en) 1988-04-15 1990-02-27 American Cyanamid Company Substituted-6H,8H-pyrimido-[1,2,3-cd]purine-8,10-(9H)-diones and substituted-6H,10H-pyrimido[1,2-cd]purin-10-ones
US5063245A (en) 1990-03-28 1991-11-05 Nova Pharmaceutical Corporation Corticotropin-releasing factor antagonism compounds
FR2692893B1 (fr) 1992-06-24 1994-09-02 Sanofi Elf Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
US6765008B1 (en) 1992-12-17 2004-07-20 Pfizer Inc Pyrrolopyrimidines as CRF antagonists
JP2781661B2 (ja) 1992-12-17 1998-07-30 フアイザー・インコーポレイテツド Ｃｒｆアンタゴニストとしての置換ピラゾール
TW370529B (en) * 1992-12-17 1999-09-21 Pfizer Pyrazolopyrimidines
CZ284157B6 (cs) 1992-12-17 1998-08-12 Pfizer Inc. Pyrazolové a pyrazolopyrimidinové sloučeniny jako takové a pro léčbu chorob a farmaceutické prostředky na jejich bázi
TW336932B (en) 1992-12-17 1998-07-21 Pfizer Amino-substituted pyrazoles
JP3398152B2 (ja) 1993-10-12 2003-04-21 ブリストル‐マイヤーズ・スクイブ・ファーマ・カンパニー １ｎ−アルキル−ｎ−アリールピリミジンアミンおよびその誘導体
TW530047B (en) * 1994-06-08 2003-05-01 Pfizer Corticotropin releasing factor antagonists
NZ284846A (en) * 1994-06-16 1998-12-23 Pfizer 1-substituted-pyrazolo[3,4-b]pyridin-5-carboxylic acid derivatives, preparation, use, intermediates and pharmaceutical compositions thereof
WO1996035689A1 (en) 1995-05-12 1996-11-14 Neurogen Corporation Novel deazapurine derivatives; a new class of crf1 specific ligands
FR2735777B1 (fr) 1995-06-21 1997-09-12 Sanofi Sa Derives de 4-phenylaminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant
WO1997035846A1 (en) 1996-03-26 1997-10-02 Dupont Pharmaceuticals Company Aryloxy- and arylthio-fused pyridines and pyrimidines and derivatives
US6326368B1 (en) 1996-03-27 2001-12-04 Dupont Pharmaceuticals Company Aryloxy- and arylthiosubstituted pyrimidines and triazines and derivatives thereof
US6107300A (en) 1996-03-27 2000-08-22 Dupont Pharmaceuticals Arylamino fused pyrimidines
ZA973884B (en) 1996-05-23 1998-11-06 Du Pont Merck Pharma Tetrahydropteridines and pyridylpiperazines for treatment of neurological disorders
EP1908764A1 (de) 1996-07-24 2008-04-09 Bristol-Myers Squibb Pharma Company Azolotriazine und Pyrimidine
DE69719193T2 (de) 1996-08-06 2003-09-25 Pfizer Substituierte pyrido- oder pyrimidogruppen enthaltende 6,6- oder 6,7-bicyclische derivate
TW477787B (en) 1996-08-27 2002-03-01 Pfizer Pyrido six-membered nitrogen-containing cyclic ring derivatives having corticotropin releasing factor antagonist activity and pharmaceutical composition containing same
SK23399A3 (en) 1996-08-28 2000-08-14 Pfizer 6,5-hetero-bicyclic derivatives, use thereof and pharmaceutical composition on their base
DE69710594T2 (de) 1996-09-16 2002-08-29 Du Pont Pharm Co Eine resorbierbare röntgenopake markierung enthaltendes chirurgisches implantat und verfahren zum verriegeln desselben in einem körper
FR2754258B1 (fr) 1996-10-08 1998-12-31 Sanofi Sa Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant
US5760225A (en) 1996-11-15 1998-06-02 Neurogen Corporation Certain pyrazole derivatives as corticotropin-releasing factor receptor CRF1 specific ligands
US5723608A (en) 1996-12-31 1998-03-03 Neurogen Corporation 3-aryl substituted pyrazolo 4,3-d!pyrimidine derivatives; corticotropin-releasing factor receptor (CRF1) specific ligands

Also Published As

Publication number Publication date
US20040229879A1 (en) 2004-11-18
EP1129096B1 (de) 2003-05-21
NO20012228D0 (no) 2001-05-04
AU755997B2 (en) 2003-01-02
WO2000027850A2 (en) 2000-05-18
DE69908173D1 (de) 2003-06-26
KR20010080402A (ko) 2001-08-22
HK1038925A1 (en) 2002-04-04
NZ511267A (en) 2002-12-20
US6723721B2 (en) 2004-04-20
ATE240958T1 (de) 2003-06-15
CN1326458A (zh) 2001-12-12
DE69908173T2 (de) 2004-08-19
ES2196898T3 (es) 2003-12-16
CN1178941C (zh) 2004-12-08
TR200102178T2 (tr) 2002-01-21
JP2002529469A (ja) 2002-09-10
BR9915129A (pt) 2001-08-07
EP1129096A2 (de) 2001-09-05
US20020143008A1 (en) 2002-10-03
CA2349904A1 (en) 2000-05-18
AU1819900A (en) 2000-05-29
US6348466B1 (en) 2002-02-19
WO2000027850A3 (en) 2000-08-03
DK1129096T3 (da) 2003-09-15
IL143105A0 (en) 2002-04-21
PT1129096E (pt) 2003-09-30
HK1038925B (zh) 2003-12-05

Similar Documents

Publication Publication Date Title
NO20012228L (no) CRF-reseptorantagonister og tilhörende fremgangsmåter
NO20012194L (no) CRF-reseptorantagonister og tilhörende fremgangsmåter
WO2001066534A3 (en) Cyclic and bicyclic diamino histamine-3 receptor antagonists
SE9900100D0 (sv) New compounds
WO1998035967A3 (en) Biazacyclic crf antagonists
MA26846A1 (fr) Derives de 2,4-diaminopyrimidine utiles comme agents immunosuppresseurs.
MXPA04006555A (es) Piridazinodionas-3,4-disustituidas como antagonistas de receptor de quimiocina cxc.
ATE308522T1 (de) Opioidrezeptorantagonisten
MXPA03006991A (es) Derivados de piperidina como antagonistas de neurocinina 1.
NO20035148D0 (no) Tri- og tetra-aza-acenaftylenderivater som CRF- reseptorantagonister
MXPA04006571A (es) Derivado de pirimidina biciclica fusionada.
TR200101654T2 (tr) Vitronektin resept”r antagonistleri
DE60100811D1 (de) Crf rezeptor-antagonisten und darauf bezogene methoden
ATE260918T1 (de) Crf rezeptor-antagonisten und darauf bezogene methoden
SE0103795D0 (sv) Compounds and method for the treatment of överactive bladder
EA200400764A1 (ru) 1,3-диарилпроп-2-ен-1-оны, композиция на их основе и применение
UY26207A1 (es) Antagonistas de los receptores de la il-8.
ITTO991117A0 (it) Procedimento per produrre 2,2,6,6-tetrametil-4-piperidone
IT1312134B1 (it) Struttura modulare per la realizzazione di arredi urbani, eprocedimento di realizzazione.
IT1311584B1 (it) Metodo per la realizzazione di calzature, e calzature ottenute contale metodo.

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application