NO20012194L - CRF-reseptorantagonister og tilhörende fremgangsmåter - Google Patents
CRF-reseptorantagonister og tilhörende fremgangsmåterInfo
- Publication number
- NO20012194L NO20012194L NO20012194A NO20012194A NO20012194L NO 20012194 L NO20012194 L NO 20012194L NO 20012194 A NO20012194 A NO 20012194A NO 20012194 A NO20012194 A NO 20012194A NO 20012194 L NO20012194 L NO 20012194L
- Authority
- NO
- Norway
- Prior art keywords
- crf receptor
- receptor antagonists
- associated methods
- crf
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/16—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Input Circuits Of Receivers And Coupling Of Receivers And Audio Equipment (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19107398A | 1998-11-12 | 1998-11-12 | |
| US37083799A | 1999-08-09 | 1999-08-09 | |
| US40136499A | 1999-09-21 | 1999-09-21 | |
| PCT/US1999/027054 WO2000027846A2 (en) | 1998-11-12 | 1999-11-12 | Crf receptor antagonists and methods relating thereto |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20012194D0 NO20012194D0 (no) | 2001-05-03 |
| NO20012194L true NO20012194L (no) | 2001-05-03 |
Family
ID=27392849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20012194A NO20012194L (no) | 1998-11-12 | 2001-05-03 | CRF-reseptorantagonister og tilhörende fremgangsmåter |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6514982B1 (no) |
| EP (1) | EP1129091B1 (no) |
| JP (1) | JP2002529465A (no) |
| KR (1) | KR20010080990A (no) |
| CN (1) | CN1217945C (no) |
| AT (1) | ATE225349T1 (no) |
| AU (1) | AU755552B2 (no) |
| CA (1) | CA2350642A1 (no) |
| DE (1) | DE69903333T2 (no) |
| DK (1) | DK1129091T3 (no) |
| ES (1) | ES2180338T3 (no) |
| HK (1) | HK1038926B (no) |
| IL (1) | IL142893A0 (no) |
| NO (1) | NO20012194L (no) |
| NZ (1) | NZ510955A (no) |
| PT (1) | PT1129091E (no) |
| WO (1) | WO2000027846A2 (no) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1129091E (pt) * | 1998-11-12 | 2003-02-28 | Neurocrine Biosciences Inc | Antagonistas de receptor de crf e metodos relacionados |
| US6531475B1 (en) * | 1998-11-12 | 2003-03-11 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods relating thereto |
| CA2398956A1 (en) * | 2000-02-14 | 2001-08-16 | Japan Tobacco Inc. | A pharmaceutical composition for prophylaxis or therapy of a postoperative stress |
| JP2003533530A (ja) | 2000-05-18 | 2003-11-11 | ニューロクライン バイオサイエンシーズ， インコーポレイテッド | Ｃｒｆレセプターアンタゴニスト |
| CA2427656A1 (en) | 2000-11-03 | 2002-05-23 | Neurocrine Biosciences, Inc. | Crf receptor antagonists and methods relating thereto |
| KR100843281B1 (ko) | 2000-12-28 | 2008-07-09 | 오노 야꾸힝 고교 가부시키가이샤 | 삼환식 복소환 유도체 화합물 및 그 화합물을 유효성분으로 하는 의약 |
| EP1345938A1 (en) | 2000-12-28 | 2003-09-24 | Neurocrine Biosciences, Inc. | Tricyclic crf receptor antagonists |
| JP2004528342A (ja) * | 2001-04-30 | 2004-09-16 | グラクソ グループ リミテッド | Ｃｒｆ受容体アンタゴニスト |
| PL367771A1 (en) * | 2001-05-21 | 2005-03-07 | Neurocrine Biosciences Inc. | Tri-and tetraaza-acenaphthylen derivatives as crf receptor antagonists |
| US7273871B2 (en) | 2001-07-17 | 2007-09-25 | Sb Pharmco Puerto Rico Inc. | Phenyl-5,6,6A,7,8,9-hexahydro-4H-1,4,9-triaza-phenalene derivatives as CRF antagonists |
| GB0117395D0 (en) * | 2001-07-17 | 2001-09-05 | Glaxo Group Ltd | Chemical compounds |
| EP2335700A1 (en) | 2001-07-25 | 2011-06-22 | Boehringer Ingelheim (Canada) Ltd. | Hepatitis C virus polymerase inhibitors with a heterobicylic structure |
| NZ544301A (en) | 2003-06-25 | 2008-08-29 | Ono Pharmaceutical Co | Methanesulfonic acid salt of pyrazolopyrimidine compound, crystal thereof, and process for producing the same |
| US20060024661A1 (en) * | 2003-07-30 | 2006-02-02 | The Regents Of The University Of California | Modulation of CRF potentiation of NMDA receptor currents via CRF receptor 2 |
| WO2005013997A1 (en) * | 2003-08-12 | 2005-02-17 | F. Hoffmann-La Roche Ag | Spiro-substituted tetrahydroquinazolines as corticotropin releasing factor (cfr) antagonists |
| US20070293508A1 (en) * | 2003-12-22 | 2007-12-20 | Sb Pharmco Puerto Rico Inc And Neurocrine Biosciences, Inc. | Crf Receptor Antagonists and Methods Relating Thereto |
| EP2626354A1 (en) | 2004-02-20 | 2013-08-14 | Boehringer Ingelheim International GmbH | Viral polymerase inhibitors |
| WO2005087775A1 (ja) * | 2004-03-15 | 2005-09-22 | Ono Pharmaceutical Co., Ltd. | 三環式複素環化合物およびその化合物を有効成分として含有する医薬組成物 |
| WO2006031322A2 (en) * | 2004-08-09 | 2006-03-23 | Research Development Foundation | Determination of the 3d-structure of an extracellular domain of a b1 g-protein coupled receptor by nmr analysis |
| CN101652365A (zh) | 2007-02-01 | 2010-02-17 | 阿斯利康(瑞典)有限公司 | 作为hsp90抑制剂的5,6,7,8-四氢蝶啶衍生物 |
| WO2010114905A1 (en) | 2009-03-31 | 2010-10-07 | Arqule, Inc. | Peri-fused pyrazolo-pyrimidine compounds |
| WO2010144486A1 (en) * | 2009-06-08 | 2010-12-16 | Takeda Pharmaceutical Company Limited | Dihydropyrrolonaphtyridinone compounds as inhibitors of jak |
| AU2010339444A1 (en) * | 2009-12-30 | 2012-07-19 | Arqule, Inc. | Substituted pyrrolo-aminopyrimidine compounds |
| CN113416191A (zh) * | 2021-04-27 | 2021-09-21 | 西安交通大学 | 一种合成三环骨架2-吡啶酮/2-吡啶亚胺类化合物的方法 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4605642A (en) | 1984-02-23 | 1986-08-12 | The Salk Institute For Biological Studies | CRF antagonists |
| US5013737A (en) * | 1988-02-22 | 1991-05-07 | American Cyanamid Company | 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones |
| US4904658A (en) | 1988-04-15 | 1990-02-27 | American Cyanamid Company | Substituted-6H,8H-pyrimido-[1,2,3-cd]purine-8,10-(9H)-diones and substituted-6H,10H-pyrimido[1,2-cd]purin-10-ones |
| US5063245A (en) | 1990-03-28 | 1991-11-05 | Nova Pharmaceutical Corporation | Corticotropin-releasing factor antagonism compounds |
| FR2692893B1 (fr) | 1992-06-24 | 1994-09-02 | Sanofi Elf | Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
| DK0674631T3 (da) | 1992-12-17 | 2000-04-10 | Pfizer | Substituerede pyrazoler som CRF-antogonister |
| TW336932B (en) | 1992-12-17 | 1998-07-21 | Pfizer | Amino-substituted pyrazoles |
| KR0170567B1 (ko) | 1992-12-17 | 1999-02-18 | 알렌 제이. 스피겔 | 부신피질자극호르몬-유리 인자 길항물질 활성을 갖는 피라졸 및 피라졸로피리미딘 |
| US6765008B1 (en) * | 1992-12-17 | 2004-07-20 | Pfizer Inc | Pyrrolopyrimidines as CRF antagonists |
| TW370529B (en) * | 1992-12-17 | 1999-09-21 | Pfizer | Pyrazolopyrimidines |
| JP3398152B2 (ja) | 1993-10-12 | 2003-04-21 | ブリストル‐マイヤーズ・スクイブ・ファーマ・カンパニー | １ｎ−アルキル−ｎ−アリールピリミジンアミンおよびその誘導体 |
| TW530047B (en) | 1994-06-08 | 2003-05-01 | Pfizer | Corticotropin releasing factor antagonists |
| JP2891544B2 (ja) * | 1994-06-16 | 1999-05-17 | ファイザー・インコーポレーテッド | ピラゾロおよびピロロピリジン類 |
| AU716993B2 (en) | 1995-05-12 | 2000-03-16 | Neurogen Corporation | Novel deazapurine derivatives; a new class of CRF1 specific ligands |
| FR2735777B1 (fr) | 1995-06-21 | 1997-09-12 | Sanofi Sa | Derives de 4-phenylaminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
| JP2000507552A (ja) | 1996-03-26 | 2000-06-20 | デュポン ファーマシューティカルズ カンパニー | アリールオキシおよびアリールチオ縮合ピリジン、アリールオキシおよびアリールチオ縮合ピリミジン、およびそれらの誘導体 |
| US6107300A (en) | 1996-03-27 | 2000-08-22 | Dupont Pharmaceuticals | Arylamino fused pyrimidines |
| US6326368B1 (en) | 1996-03-27 | 2001-12-04 | Dupont Pharmaceuticals Company | Aryloxy- and arylthiosubstituted pyrimidines and triazines and derivatives thereof |
| ZA973884B (en) | 1996-05-23 | 1998-11-06 | Du Pont Merck Pharma | Tetrahydropteridines and pyridylpiperazines for treatment of neurological disorders |
| EP0915880B1 (en) | 1996-07-24 | 2007-10-10 | Bristol-Myers Squibb Pharma Company | Azolo triazines and pyrimidines |
| ATE232863T1 (de) | 1996-08-06 | 2003-03-15 | Pfizer | Substituierte pyrido- oder pyrimidogruppen enthaltende 6,6- oder 6,7-bicyclische derivate |
| TW477787B (en) | 1996-08-27 | 2002-03-01 | Pfizer | Pyrido six-membered nitrogen-containing cyclic ring derivatives having corticotropin releasing factor antagonist activity and pharmaceutical composition containing same |
| AU735401B2 (en) | 1996-08-28 | 2001-07-05 | Pfizer Inc. | Substituted 6,5-hetero-bicyclic derivatives |
| EP0927171B1 (en) | 1996-09-16 | 2002-02-20 | Du Pont Pharmaceuticals Company | Pyrazinones and triazinones and their derivatives thereof |
| FR2754258B1 (fr) | 1996-10-08 | 1998-12-31 | Sanofi Sa | Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
| US5760225A (en) | 1996-11-15 | 1998-06-02 | Neurogen Corporation | Certain pyrazole derivatives as corticotropin-releasing factor receptor CRF1 specific ligands |
| US5723608A (en) | 1996-12-31 | 1998-03-03 | Neurogen Corporation | 3-aryl substituted pyrazolo 4,3-d!pyrimidine derivatives; corticotropin-releasing factor receptor (CRF1) specific ligands |
| US6187777B1 (en) | 1998-02-06 | 2001-02-13 | Amgen Inc. | Compounds and methods which modulate feeding behavior and related diseases |
| PT1129091E (pt) * | 1998-11-12 | 2003-02-28 | Neurocrine Biosciences Inc | Antagonistas de receptor de crf e metodos relacionados |
-
1999
- 1999-11-12 PT PT99960363T patent/PT1129091E/pt unknown
- 1999-11-12 NZ NZ510955A patent/NZ510955A/xx unknown
- 1999-11-12 EP EP99960363A patent/EP1129091B1/en not_active Expired - Lifetime
- 1999-11-12 ES ES99960363T patent/ES2180338T3/es not_active Expired - Lifetime
- 1999-11-12 IL IL14289399A patent/IL142893A0/xx unknown
- 1999-11-12 US US09/439,840 patent/US6514982B1/en not_active Expired - Lifetime
- 1999-11-12 JP JP2000581024A patent/JP2002529465A/ja active Pending
- 1999-11-12 KR KR1020017005924A patent/KR20010080990A/ko not_active Application Discontinuation
- 1999-11-12 DK DK99960363T patent/DK1129091T3/da active
- 1999-11-12 AT AT99960363T patent/ATE225349T1/de not_active IP Right Cessation
- 1999-11-12 DE DE69903333T patent/DE69903333T2/de not_active Expired - Lifetime
- 1999-11-12 WO PCT/US1999/027054 patent/WO2000027846A2/en not_active Application Discontinuation
- 1999-11-12 CN CN998131717A patent/CN1217945C/zh not_active Expired - Fee Related
- 1999-11-12 CA CA002350642A patent/CA2350642A1/en not_active Abandoned
- 1999-11-12 AU AU17258/00A patent/AU755552B2/en not_active Ceased
-
2001
- 2001-05-03 NO NO20012194A patent/NO20012194L/no not_active Application Discontinuation
-
2002
- 2002-01-29 HK HK02100690.1A patent/HK1038926B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ510955A (en) | 2003-01-31 |
| DK1129091T3 (da) | 2002-11-04 |
| NO20012194D0 (no) | 2001-05-03 |
| WO2000027846A3 (en) | 2000-11-16 |
| JP2002529465A (ja) | 2002-09-10 |
| AU755552B2 (en) | 2002-12-12 |
| DE69903333T2 (de) | 2003-08-07 |
| ES2180338T3 (es) | 2003-02-01 |
| US6514982B1 (en) | 2003-02-04 |
| AU1725800A (en) | 2000-05-29 |
| IL142893A0 (en) | 2002-04-21 |
| WO2000027846A2 (en) | 2000-05-18 |
| ATE225349T1 (de) | 2002-10-15 |
| EP1129091B1 (en) | 2002-10-02 |
| KR20010080990A (ko) | 2001-08-25 |
| CA2350642A1 (en) | 2000-05-18 |
| EP1129091A2 (en) | 2001-09-05 |
| HK1038926B (zh) | 2003-07-18 |
| CN1217945C (zh) | 2005-09-07 |
| CN1328559A (zh) | 2001-12-26 |
| DE69903333D1 (de) | 2002-11-07 |
| HK1038926A1 (en) | 2002-05-10 |
| PT1129091E (pt) | 2003-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |