NO20011211L - Multippel enhet for kontrollert mateffektuavhengig frigivelse av farmasöytiske preparater og fremgangsmåter for fremstilling avsamme - Google Patents
Multippel enhet for kontrollert mateffektuavhengig frigivelse av farmasöytiske preparater og fremgangsmåter for fremstilling avsammeInfo
- Publication number
- NO20011211L NO20011211L NO20011211A NO20011211A NO20011211L NO 20011211 L NO20011211 L NO 20011211L NO 20011211 A NO20011211 A NO 20011211A NO 20011211 A NO20011211 A NO 20011211A NO 20011211 L NO20011211 L NO 20011211L
- Authority
- NO
- Norway
- Prior art keywords
- methods
- pharmaceutical preparations
- multiple unit
- food effect
- dependent release
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 2
- 238000013019 agitation Methods 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nonmetallic Welding Materials (AREA)
- General Preparation And Processing Of Foods (AREA)
Abstract
Foreliggende oppfinnelse angår oralt administrerbare multi-enhets vedvarende frigivelses doseformer som har kontrollert agitasjonsuavhengig frigivelse av aktiv forbindelse og fremgangsmåter for deres fremstilling ved anvendelse av en utvalgt eroderbar hydrofil polymer (HPC) og en begrensning av maksimumstørrelsen for aktiv forbindelse-inneholdende polymerpartikler på < 3 mm.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19842753A DE19842753A1 (de) | 1998-09-18 | 1998-09-18 | Agitationsunabhängige pharmazeutische Retardzubereitungen und Verfahren zu ihrer Herstellung |
PCT/EP1999/006882 WO2000016748A1 (de) | 1998-09-18 | 1999-09-17 | Agitationsunabhängige pharmazeutische multiple-unit-retardzubereitungen und verfahren zu ihrer herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20011211L true NO20011211L (no) | 2001-03-09 |
NO20011211D0 NO20011211D0 (no) | 2001-03-09 |
Family
ID=7881376
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20011211A NO20011211D0 (no) | 1998-09-18 | 2001-03-09 | Multippel enhet for kontrollert mateffektuavhengig frigivelse av farmasøytiske preparater og fremgangsmÕter for fremstilling av samme |
Country Status (29)
Country | Link |
---|---|
US (1) | US6805881B1 (no) |
EP (1) | EP1113787B1 (no) |
JP (1) | JP2002526437A (no) |
KR (1) | KR100660072B1 (no) |
CN (1) | CN1178650C (no) |
AT (1) | ATE260645T1 (no) |
AU (2) | AU5861499A (no) |
BG (1) | BG105325A (no) |
BR (1) | BR9913839A (no) |
CA (1) | CA2344372C (no) |
DE (2) | DE19842753A1 (no) |
DK (1) | DK1113787T3 (no) |
EE (1) | EE04700B1 (no) |
ES (1) | ES2215404T3 (no) |
HK (1) | HK1040932B (no) |
HR (1) | HRP20010198A2 (no) |
HU (1) | HUP0103669A3 (no) |
ID (1) | ID28735A (no) |
IL (2) | IL141532A0 (no) |
NO (1) | NO20011211D0 (no) |
NZ (1) | NZ510563A (no) |
PL (1) | PL195543B1 (no) |
PT (1) | PT1113787E (no) |
RU (1) | RU2235540C2 (no) |
SK (1) | SK285099B6 (no) |
TR (1) | TR200100756T2 (no) |
UA (1) | UA73097C2 (no) |
WO (2) | WO2000016747A1 (no) |
ZA (1) | ZA200101485B (no) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19962924A1 (de) * | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
DE10026698A1 (de) | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
US20020044962A1 (en) * | 2000-06-06 | 2002-04-18 | Cherukuri S. Rao | Encapsulation products for controlled or extended release |
DE10129725A1 (de) * | 2001-06-20 | 2003-01-02 | Bayer Ag | Kombinationstherapie substituierter Oxazolidinone |
AR034813A1 (es) † | 2001-07-20 | 2004-03-17 | Novartis Ag | Composiciones farmaceuticas y uso de las mismas |
DE10300111A1 (de) * | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid |
US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
DE10355461A1 (de) | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung |
DE102004062475A1 (de) * | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
RU2401125C2 (ru) | 2004-12-27 | 2010-10-10 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Способ стабилизации лекарственного средства против деменции |
US20070129402A1 (en) * | 2004-12-27 | 2007-06-07 | Eisai Research Institute | Sustained release formulations |
EP1685841A1 (en) | 2005-01-31 | 2006-08-02 | Bayer Health Care Aktiengesellschaft | Prevention and treatment of thromboembolic disorders |
DE102005012561B4 (de) | 2005-03-18 | 2008-06-19 | Christian Beer | Verfahren zum Betrieb eines Werkstück-Transfersystems |
DE102005045518A1 (de) * | 2005-09-23 | 2007-03-29 | Bayer Healthcare Ag | 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung |
DE102005047561A1 (de) | 2005-10-04 | 2007-04-05 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung |
CA2624310C (en) | 2005-10-04 | 2014-01-07 | Bayer Healthcare Ag | Polymorphic form of 5-chloro-n-({5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide |
DE102005047558A1 (de) * | 2005-10-04 | 2008-02-07 | Bayer Healthcare Ag | Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen |
CN100448432C (zh) * | 2006-10-26 | 2009-01-07 | 徐竹青 | 高溶出度尼莫地平分散片的制备方法 |
DE102006051625A1 (de) * | 2006-11-02 | 2008-05-08 | Bayer Materialscience Ag | Kombinationstherapie substituierter Oxazolidinone |
US7952167B2 (en) * | 2007-04-27 | 2011-05-31 | Taiwan Semiconductor Manufacturing Company, Ltd. | Scribe line layout design |
ES2525648T3 (es) * | 2009-01-28 | 2014-12-26 | Novartis Ag | Formulaciones galénicas que comprenden Aliskiren |
US20100247646A1 (en) * | 2009-03-26 | 2010-09-30 | Ranbaxy Laboratories Limited | Extended release tablets of nisoldipine |
TR201802207T4 (tr) | 2010-03-29 | 2018-03-21 | Astellas Pharma Inc | Kontrollü Salımlı Farmasötik Bileşim. |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5482525A (en) | 1977-12-13 | 1979-06-30 | Aisan Ind Co Ltd | Exhaust gas recirculation system |
US4226849A (en) * | 1979-06-14 | 1980-10-07 | Forest Laboratories Inc. | Sustained release therapeutic compositions |
US4327725A (en) | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
US4369172A (en) * | 1981-12-18 | 1983-01-18 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
US4449983A (en) | 1982-03-22 | 1984-05-22 | Alza Corporation | Simultaneous delivery of two drugs from unit delivery device |
US4389393A (en) * | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
GB8514665D0 (en) * | 1985-06-11 | 1985-07-10 | Eroceltique Sa | Oral pharmaceutical composition |
DE3612212A1 (de) | 1986-04-11 | 1987-10-15 | Basf Ag | Verfahren zur herstellung von festen pharmazeutischen formen |
DE3612211A1 (de) | 1986-04-11 | 1987-10-15 | Basf Ag | Kontinuierliches verfahren zum tablettieren |
DE3720757A1 (de) | 1987-06-24 | 1989-01-05 | Bayer Ag | Dhp-manteltablette |
DE3830353A1 (de) | 1988-09-07 | 1990-03-15 | Basf Ag | Verfahren zur kontinuierlichen herstellung von festen pharmazeutischen formen |
JPH03145418A (ja) | 1989-10-27 | 1991-06-20 | Sumitomo Pharmaceut Co Ltd | 塩基性薬物塩酸塩の徐放性製剤 |
WO1992018106A1 (en) | 1991-04-16 | 1992-10-29 | Nippon Shinyaku Co., Ltd. | Method of manufacturing solid dispersion |
DE4138513A1 (de) | 1991-11-23 | 1993-05-27 | Basf Ag | Feste pharmazeutische retardform |
DE4413350A1 (de) | 1994-04-18 | 1995-10-19 | Basf Ag | Retard-Matrixpellets und Verfahren zu ihrer Herstellung |
SE9402422D0 (sv) * | 1994-07-08 | 1994-07-08 | Astra Ab | New beads for controlled release and a pharmaceutical preparation containing the same |
FR2725624B1 (fr) | 1994-10-14 | 1997-01-17 | Jouveinal Inst Rech | Procede de preparation de formes pharmaceutiques a liberation controlee |
DE19504831A1 (de) | 1995-02-14 | 1996-09-05 | Basf Ag | Feste Wirkstoffzubereitungen enthaltend Hydroxypropylcellulose |
-
1998
- 1998-09-18 DE DE19842753A patent/DE19842753A1/de not_active Withdrawn
-
1999
- 1999-09-08 WO PCT/EP1999/006608 patent/WO2000016747A1/de active Application Filing
- 1999-09-08 AU AU58614/99A patent/AU5861499A/en not_active Abandoned
- 1999-09-17 ID IDW20010651A patent/ID28735A/id unknown
- 1999-09-17 UA UA2001042576A patent/UA73097C2/uk unknown
- 1999-09-17 WO PCT/EP1999/006882 patent/WO2000016748A1/de active IP Right Grant
- 1999-09-17 EP EP99948770A patent/EP1113787B1/de not_active Expired - Lifetime
- 1999-09-17 NZ NZ510563A patent/NZ510563A/xx unknown
- 1999-09-17 AU AU61918/99A patent/AU750617B2/en not_active Ceased
- 1999-09-17 ES ES99948770T patent/ES2215404T3/es not_active Expired - Lifetime
- 1999-09-17 IL IL14153299A patent/IL141532A0/xx not_active IP Right Cessation
- 1999-09-17 TR TR2001/00756T patent/TR200100756T2/xx unknown
- 1999-09-17 HU HU0103669A patent/HUP0103669A3/hu unknown
- 1999-09-17 EE EEP200100161A patent/EE04700B1/xx not_active IP Right Cessation
- 1999-09-17 CA CA002344372A patent/CA2344372C/en not_active Expired - Fee Related
- 1999-09-17 SK SK372-2001A patent/SK285099B6/sk unknown
- 1999-09-17 PT PT99948770T patent/PT1113787E/pt unknown
- 1999-09-17 RU RU2001110355/15A patent/RU2235540C2/ru not_active IP Right Cessation
- 1999-09-17 AT AT99948770T patent/ATE260645T1/de not_active IP Right Cessation
- 1999-09-17 DK DK99948770T patent/DK1113787T3/da active
- 1999-09-17 DE DE59908764T patent/DE59908764D1/de not_active Expired - Lifetime
- 1999-09-17 CN CNB998110299A patent/CN1178650C/zh not_active Expired - Fee Related
- 1999-09-17 KR KR1020017003495A patent/KR100660072B1/ko not_active IP Right Cessation
- 1999-09-17 JP JP2000573709A patent/JP2002526437A/ja not_active Ceased
- 1999-09-17 US US09/787,229 patent/US6805881B1/en not_active Expired - Fee Related
- 1999-09-17 BR BR9913839-5A patent/BR9913839A/pt not_active Application Discontinuation
- 1999-09-17 PL PL99346535A patent/PL195543B1/pl unknown
-
2001
- 2001-02-20 IL IL141532A patent/IL141532A/en unknown
- 2001-02-22 ZA ZA200101485A patent/ZA200101485B/en unknown
- 2001-03-09 BG BG105325A patent/BG105325A/bg unknown
- 2001-03-09 NO NO20011211A patent/NO20011211D0/no not_active Application Discontinuation
- 2001-03-16 HR HR20010198A patent/HRP20010198A2/hr not_active Application Discontinuation
-
2002
- 2002-04-11 HK HK02102756.8A patent/HK1040932B/zh not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |