HUP0401429A2 - Lumirakoxibot tartalmazó gyógyszerkészítmény - Google Patents
Lumirakoxibot tartalmazó gyógyszerkészítményInfo
- Publication number
- HUP0401429A2 HUP0401429A2 HU0401429A HUP0401429A HUP0401429A2 HU P0401429 A2 HUP0401429 A2 HU P0401429A2 HU 0401429 A HU0401429 A HU 0401429A HU P0401429 A HUP0401429 A HU P0401429A HU P0401429 A2 HUP0401429 A2 HU P0401429A2
- Authority
- HU
- Hungary
- Prior art keywords
- treatment
- cyclooxygenase
- mediated diseases
- lumiracoxib
- pharmaceutical composition
- Prior art date
Links
- KHPKQFYUPIUARC-UHFFFAOYSA-N lumiracoxib Chemical compound OC(=O)CC1=CC(C)=CC=C1NC1=C(F)C=CC=C1Cl KHPKQFYUPIUARC-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000994 lumiracoxib Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 102000010907 Cyclooxygenase 2 Human genes 0.000 abstract 2
- 108010037462 Cyclooxygenase 2 Proteins 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 2
- 229920002785 Croscarmellose sodium Polymers 0.000 abstract 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 229960001681 croscarmellose sodium Drugs 0.000 abstract 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 229940057948 magnesium stearate Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 1
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 1
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A találmány készítményre vonatkozik ciklooxigenáz-2 által közvetítettbetegségek kezelésére, és az eljárásra a ciklooxigenáz-2 általközvetített betegségek kezelésére. A találmány szerinti készítménykörülbelül 65 tömeg% 5-metil-2-(2'klór-6'-fluor-anilino)-fenil-ecetsavhatóanyagot vagy sóját, és segédanyagokként polivinilpirrolidont,croscarmellose-nátriumot, magnézium-sztearátot és mikrokristályoscellulózt tartalmaz. A kezelést napi egy, azonnal felszabadulótablettával végzik, amely körülbelül 400 mg hatóanyagot tartalmaz. Abeadás orálisan történik. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31638901P | 2001-08-31 | 2001-08-31 | |
PCT/EP2002/009701 WO2003020261A1 (en) | 2001-08-31 | 2002-08-30 | Pharmaceutical composition comprising lumiracoxib |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP0401429A2 true HUP0401429A2 (hu) | 2004-11-29 |
Family
ID=23228840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0401429A HUP0401429A2 (hu) | 2001-08-31 | 2002-08-30 | Lumirakoxibot tartalmazó gyógyszerkészítmény |
Country Status (30)
Country | Link |
---|---|
US (2) | US20030114527A1 (hu) |
EP (1) | EP1425005B1 (hu) |
JP (1) | JP4636796B2 (hu) |
KR (1) | KR100895551B1 (hu) |
CN (1) | CN100406008C (hu) |
AR (1) | AR036312A1 (hu) |
AT (1) | ATE324883T1 (hu) |
AU (1) | AU2002331094B2 (hu) |
BR (1) | BR0212155A (hu) |
CA (1) | CA2456604C (hu) |
CO (1) | CO5560554A2 (hu) |
CY (1) | CY1106137T1 (hu) |
DE (1) | DE60211183T2 (hu) |
DK (1) | DK1425005T3 (hu) |
EC (1) | ECSP044986A (hu) |
ES (1) | ES2263813T3 (hu) |
HK (1) | HK1087336A1 (hu) |
HU (1) | HUP0401429A2 (hu) |
IL (1) | IL160375A0 (hu) |
MX (1) | MXPA04001933A (hu) |
MY (1) | MY137516A (hu) |
NO (1) | NO20040860L (hu) |
NZ (1) | NZ531342A (hu) |
PE (1) | PE20030323A1 (hu) |
PL (1) | PL367464A1 (hu) |
PT (1) | PT1425005E (hu) |
RU (1) | RU2329801C2 (hu) |
SI (1) | SI1425005T1 (hu) |
WO (1) | WO2003020261A1 (hu) |
ZA (1) | ZA200400877B (hu) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20020351A1 (es) * | 2000-09-11 | 2002-06-14 | Novartis Ag | Composiciones farmaceuticas que comprenden acido 5-metil-2-(2'-cloro-6'-fluoroanilino)fenilacetico como inhibidor de la ciclooxigenasa-2 |
GB0201520D0 (en) * | 2002-01-23 | 2002-03-13 | Novartis Ag | Pharmaceutical uses |
AU2003227039B2 (en) * | 2002-03-07 | 2007-04-19 | Novartis Ag | Pharmaceutical compositions |
US8148414B2 (en) | 2008-08-19 | 2012-04-03 | Xenoport, Inc. | Prodrugs of methyl hydrogen fumarate, pharmaceutical compositions thereof, and methods of use |
US20140093563A1 (en) * | 2011-06-13 | 2014-04-03 | Ranbaxy Laboratories Limited | Febuxostat compositions |
ES2903149T3 (es) | 2012-05-14 | 2022-03-31 | Shionogi & Co | Preparación que contiene derivado de 7-carbamoilmorfinano 6,7-insaturado |
US10945984B2 (en) | 2012-08-22 | 2021-03-16 | Arbor Pharmaceuticals, Llc | Methods of administering monomethyl fumarate and prodrugs thereof having reduced side effects |
US20140056973A1 (en) | 2012-08-22 | 2014-02-27 | Xenoport, Inc. | Oral Dosage Forms Having a High Loading of a Methyl Hydrogen Fumarate Prodrug |
EA018867B1 (ru) * | 2012-11-01 | 2013-11-29 | Лаборатория Тютор С.А.С.И.Ф.И.А. | Способ получения фармацевтической композиции и продукт способа |
WO2014160633A1 (en) | 2013-03-24 | 2014-10-02 | Xenoport, Inc. | Pharmaceutical compositions of dimethyl fumarate |
US9302977B2 (en) | 2013-06-07 | 2016-04-05 | Xenoport, Inc. | Method of making monomethyl fumarate |
WO2014205392A1 (en) | 2013-06-21 | 2014-12-24 | Xenoport, Inc. | Cocrystals of dimethyl fumarate |
EP3041467A1 (en) | 2013-09-06 | 2016-07-13 | XenoPort, Inc. | Crystalline forms of (n,n-diethylcarbamoyl)methyl methyl (2e)but-2-ene-1,4-dioate, methods of synthesis and use |
ES2750323T3 (es) * | 2014-01-10 | 2020-03-25 | Johnson & Johnson Consumer Inc | Método para la fabricación de un comprimido mediante radiofrecuencia y partículas recubiertas con pérdida |
US9999672B2 (en) | 2014-03-24 | 2018-06-19 | Xenoport, Inc. | Pharmaceutical compositions of fumaric acid esters |
EP3162362A1 (de) * | 2015-10-30 | 2017-05-03 | Dr. Falk Pharma Gmbh | Optimierte mesalazinhaltige hochdosistablette |
US10493026B2 (en) | 2017-03-20 | 2019-12-03 | Johnson & Johnson Consumer Inc. | Process for making tablet using radiofrequency and lossy coated particles |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE246515T1 (de) * | 1993-06-08 | 2003-08-15 | Novartis Pharma Gmbh | Verfahren zur herstellung von oralen dosierungsformulierungen enthaltend diclofenac |
TR199802345T2 (xx) * | 1996-05-17 | 1999-03-22 | Merck & Co., Inc. | Siklooksijenaz-2-arac�l� hastal�klarda g�nde bir kez tatbikat i�in bile�imler. |
CO4960662A1 (es) * | 1997-08-28 | 2000-09-25 | Novartis Ag | Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados |
SA99191255B1 (ar) * | 1998-11-30 | 2006-11-25 | جي دي سيرل اند كو | مركبات سيليكوكسيب celecoxib |
PE20020351A1 (es) * | 2000-09-11 | 2002-06-14 | Novartis Ag | Composiciones farmaceuticas que comprenden acido 5-metil-2-(2'-cloro-6'-fluoroanilino)fenilacetico como inhibidor de la ciclooxigenasa-2 |
-
2002
- 2002-08-29 PE PE2002000832A patent/PE20030323A1/es not_active Application Discontinuation
- 2002-08-29 US US10/231,438 patent/US20030114527A1/en not_active Abandoned
- 2002-08-29 AR ARP020103257A patent/AR036312A1/es unknown
- 2002-08-30 AU AU2002331094A patent/AU2002331094B2/en not_active Ceased
- 2002-08-30 ES ES02767455T patent/ES2263813T3/es not_active Expired - Lifetime
- 2002-08-30 PT PT02767455T patent/PT1425005E/pt unknown
- 2002-08-30 SI SI200230367T patent/SI1425005T1/sl unknown
- 2002-08-30 CN CNB02816895XA patent/CN100406008C/zh not_active Expired - Fee Related
- 2002-08-30 IL IL16037502A patent/IL160375A0/xx unknown
- 2002-08-30 NZ NZ531342A patent/NZ531342A/en not_active IP Right Cessation
- 2002-08-30 DK DK02767455T patent/DK1425005T3/da active
- 2002-08-30 EP EP02767455A patent/EP1425005B1/en not_active Expired - Lifetime
- 2002-08-30 RU RU2004109920/15A patent/RU2329801C2/ru not_active IP Right Cessation
- 2002-08-30 KR KR1020047002925A patent/KR100895551B1/ko not_active IP Right Cessation
- 2002-08-30 HU HU0401429A patent/HUP0401429A2/hu unknown
- 2002-08-30 CA CA2456604A patent/CA2456604C/en not_active Expired - Fee Related
- 2002-08-30 PL PL02367464A patent/PL367464A1/xx not_active Application Discontinuation
- 2002-08-30 MX MXPA04001933A patent/MXPA04001933A/es active IP Right Grant
- 2002-08-30 JP JP2003524569A patent/JP4636796B2/ja not_active Expired - Fee Related
- 2002-08-30 WO PCT/EP2002/009701 patent/WO2003020261A1/en active IP Right Grant
- 2002-08-30 MY MYPI20023252A patent/MY137516A/en unknown
- 2002-08-30 BR BR0212155-7A patent/BR0212155A/pt not_active IP Right Cessation
- 2002-08-30 DE DE60211183T patent/DE60211183T2/de not_active Expired - Lifetime
- 2002-08-30 AT AT02767455T patent/ATE324883T1/de active
-
2004
- 2004-02-03 ZA ZA200400877A patent/ZA200400877B/en unknown
- 2004-02-25 CO CO04016658A patent/CO5560554A2/es not_active Application Discontinuation
- 2004-02-25 EC EC2004004986A patent/ECSP044986A/es unknown
- 2004-02-26 NO NO20040860A patent/NO20040860L/no not_active Application Discontinuation
-
2006
- 2006-07-10 HK HK06107694.8A patent/HK1087336A1/xx not_active IP Right Cessation
- 2006-08-03 CY CY20061101093T patent/CY1106137T1/el unknown
-
2007
- 2007-05-17 US US11/804,284 patent/US20070231382A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |