NO20006257L - Artemisininderivater, fremgangsmåte ved fremstilling derav samt farmasöytiske sammensetninger inneholdende slike - Google Patents

Artemisininderivater, fremgangsmåte ved fremstilling derav samt farmasöytiske sammensetninger inneholdende slike

Info

Publication number
NO20006257L
NO20006257L NO20006257A NO20006257A NO20006257L NO 20006257 L NO20006257 L NO 20006257L NO 20006257 A NO20006257 A NO 20006257A NO 20006257 A NO20006257 A NO 20006257A NO 20006257 L NO20006257 L NO 20006257L
Authority
NO
Norway
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
artemisinin derivatives
artemisinin
Prior art date
Application number
NO20006257A
Other languages
English (en)
Other versions
NO20006257D0 (no
Inventor
Ying Li
Feng Shan
Jin Ming Wu
Guangshao Wu
Jian Ding
Jianxian Han
Ghanem Atassi
Pierre Renard
Original Assignee
Adir
Shanghai Inst Materia Medica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir, Shanghai Inst Materia Medica filed Critical Adir
Publication of NO20006257D0 publication Critical patent/NO20006257D0/no
Publication of NO20006257L publication Critical patent/NO20006257L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/20—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20006257A 1998-06-17 2000-12-08 Artemisininderivater, fremgangsmåte ved fremstilling derav samt farmasöytiske sammensetninger inneholdende slike NO20006257L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN98114788A CN1084333C (zh) 1998-06-17 1998-06-17 新的青蒿素化合物,其制备方法以及含有它们的药物组合物
PCT/FR1999/001359 WO1999065914A1 (fr) 1998-06-17 1999-06-09 Derives de l'artemisinine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
NO20006257D0 NO20006257D0 (no) 2000-12-08
NO20006257L true NO20006257L (no) 2001-02-19

Family

ID=5224325

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20006257A NO20006257L (no) 1998-06-17 2000-12-08 Artemisininderivater, fremgangsmåte ved fremstilling derav samt farmasöytiske sammensetninger inneholdende slike

Country Status (14)

Country Link
US (1) US6307068B1 (no)
EP (1) EP1086107A1 (no)
JP (1) JP2002518398A (no)
CN (2) CN1084333C (no)
AU (1) AU748798B2 (no)
BR (1) BR9911274A (no)
CA (1) CA2342990A1 (no)
HK (1) HK1036985A1 (no)
HU (1) HUP0102599A3 (no)
NO (1) NO20006257L (no)
NZ (1) NZ508388A (no)
PL (1) PL344984A1 (no)
WO (1) WO1999065914A1 (no)
ZA (1) ZA200007070B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0129215D0 (en) * 2001-12-06 2002-01-23 Ufc Ltd Trioxane derivatives
CA2469224A1 (en) * 2001-12-06 2003-06-12 Ufc Limited Trioxane derivatives
US20050070595A1 (en) * 2001-12-06 2005-03-31 O'neil Paul Michael Trioxane derivatives as antimalaria or anticancer compounds
RU2325156C2 (ru) * 2002-06-06 2008-05-27 Юниверсити Оф Вашингтон Ковалентные конъюгаты между родственными артемизинину эндопероксидами и железосодержащими белками и способы применения
ES2377002T3 (es) * 2002-06-06 2012-03-21 University Of Washington Conjugados covalentes entre los endoperóxidos relacionados con la artemisinina y las proteínas transportadoras de hierro y procedimientos de utilización
US6677463B1 (en) * 2002-12-10 2004-01-13 Council Of Scientific And Industrial Research Single pot conversion of artemisinin to artesunic acid
CN1327842C (zh) * 2003-02-12 2007-07-25 沈恒 一种新型的抗肿瘤药物复方制备方法
WO2006002105A1 (en) 2004-06-21 2006-01-05 University Of Mississippi Anticancer and antiprotozoal dihydroartemisinene and dihydroartemisitene dimers with desirable chemical functionalities
CN1814601A (zh) * 2005-02-04 2006-08-09 中国科学院上海药物研究所 具有免疫抑制作用的青蒿素衍生物及药物组合物
FR2899586B1 (fr) 2006-04-11 2008-06-20 Sanofi Aventis Sa Dimeres de derives d'artemisinine, leur preparation et leur application en therapeutique
ITMI20071915A1 (it) * 2007-10-04 2009-04-05 Lachifarma Srl Lab Chimico Far Derivati dell'artemisinina per il trattamento del melanoma
GB0720967D0 (en) * 2007-10-25 2007-12-05 Protophama Ltd Anti-material pharmaceutical composition
GB2469791B (en) * 2009-04-23 2011-12-14 Londonpharma Ltd Transmucosal formulation of compounds providing dihydroartemesinin for use in the treatment of neoplastic disease
US8815942B2 (en) 2010-10-20 2014-08-26 The Royal Institution For The Advancement Of Learning/Mcgill University Combination therapy and uses thereof for treatment and prevention of parasitic infection and disease
CN103570738B (zh) * 2012-08-07 2016-04-13 中国科学院上海生命科学研究院 新型青蒿素衍生物及其制法和应用
EP3450549B1 (en) 2012-10-29 2020-09-30 University Of Rochester Artemisinin derivatives, methods for their preparation and their use as antimalarial agents
CN117695222B (zh) * 2024-02-06 2024-04-26 山东百奥生物医药有限公司 一种用于改善皮肤问题的青蒿素壬二酸酯-聚乙二醇二胺胶束及制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916204A (en) * 1987-07-31 1990-04-10 Massachusetts Institute Of Technology Pure polyanhydride from dicarboxylic acid and coupling agent
CN1049435A (zh) * 1990-08-16 1991-02-20 中国对外贸易运输总公司 电传线路自动转换开关
US5219880A (en) * 1991-03-29 1993-06-15 Dermatologic Research Corporation Treatment of viral tumors and hemorrhoids with artemisinin and derivatives
CN1038416C (zh) * 1992-12-04 1998-05-20 中国科学院上海药物研究所 新型青蒿素衍生物及其制备方法
CN1049435C (zh) * 1994-11-09 2000-02-16 中国科学院上海药物研究所 含苯基和杂环基的青蒿素衍生物及其制备方法
US5578637A (en) * 1995-05-03 1996-11-26 University Of Washington Methods of inhibition or killing cancer cells using an endoperoxide
US5677468A (en) 1995-06-29 1997-10-14 Hauser, Inc. Artemisinin dimer compounds having anticancer activity

Also Published As

Publication number Publication date
CN1305482A (zh) 2001-07-25
NZ508388A (en) 2003-07-25
ZA200007070B (en) 2001-10-18
PL344984A1 (en) 2001-11-19
AU748798B2 (en) 2002-06-13
JP2002518398A (ja) 2002-06-25
US6307068B1 (en) 2001-10-23
EP1086107A1 (fr) 2001-03-28
WO1999065914A1 (fr) 1999-12-23
BR9911274A (pt) 2001-10-23
CA2342990A1 (fr) 1999-12-23
CN1084333C (zh) 2002-05-08
CN1239097A (zh) 1999-12-22
NO20006257D0 (no) 2000-12-08
AU4047499A (en) 2000-01-05
HUP0102599A2 (hu) 2001-11-28
HUP0102599A3 (en) 2003-03-28
CN1111162C (zh) 2003-06-11
HK1036985A1 (en) 2002-01-25

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application